• 가정과삶의질연구
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• 제25권4호
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• pp.197-216
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• 2007

The Purpose of this research is to perform survey on employees of Non-Government Consumer Organization and interview with ADR personnel from Korean Consumer Protection Board to have thorough grasp of problems among consumer ADR. Also come up with plan that will activate Non-Government Consumer organization ADR. Result of this research states following remarks as solution First, consumers from Seoul and Gyeonggi area is the only people who use ADR in Non-Government Consumer organization, so other local governments need to concentrate on consumers from rural area to take advantage of the service. Second, low activity of ADR and legal procedure support compare to other services provide from Non-Government Consumer organization. Third, statistic shows that employees from Non-Government Consumer organization recognize importance of consumer's ADR and government's support as well as enforcement of law. Forth, the preparation of Consumer ADR in Non-Government Consumer organization, selecting committee is the most important procedures are reinforce human resource, improvement of organization structure. Fifty, order to establish Consumer ADR in Non-Government Consumer organization, recruit professional manpower is the priority and financial support is also important. All these result would help improve the activity of ADR in Non-Government Consumer organization, which will lead the organization to be more professionalize, globalize and able to segment the market. Further more, Non-Government Consumer organization would develop better ways to take itself to another level to provide better service. Also, create an institution that will help consumer's dispute and legal procedure. It will prevent future victims and protect consumer's right.

• Clinical Psychopharmacology and Neuroscience
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• 제16권4호
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• pp.449-460
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• 2018

Objective: Prior functional magnetic resonance imaging (fMRI) work has revealed that children/adolescents with disruptive behavior disorders (DBDs) show dysfunctional reward/non-reward processing of non-social reinforcements in the context of instrumental learning tasks. Neural responsiveness to social reinforcements during instrumental learning, despite the importance of this for socialization, has not yet been previously investigated. Methods: Twenty-nine healthy children/adolescents and 19 children/adolescents with DBDs performed the fMRI social/non-social reinforcement learning task. Participants responded to random fractal image stimuli and received social and non-social rewards/non-rewards according to their accuracy. Results: Children/adolescents with DBDs showed significantly reduced responses within the caudate and posterior cingulate cortex (PCC) to non-social (financial) rewards and social non-rewards (the distress of others). Connectivity analyses revealed that children/adolescents with DBDs have decreased positive functional connectivity between the ventral striatum (VST) and the ventromedial prefrontal cortex (vmPFC) seeds and the lateral frontal cortex in response to reward relative to non-reward, irrespective of its sociality. In addition, they showed decreased positive connectivity between the vmPFC seed and the amygdala in response to non-reward relative to reward. Conclusion: These data indicate compromised reinforcement processing of both non-social rewards and social non-rewards in children/adolescents with DBDs within core regions for instrumental learning and reinforcement-based decision-making (caudate and PCC). In addition, children/adolescents with DBDs show dysfunctional interactions between the VST, vmPFC, and lateral frontal cortex in response to rewarded instrumental actions potentially reflecting disruptions in attention to rewarded stimuli.

• 융합정보논문지
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• 제10권11호
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• pp.185-194
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• 2020

제 4차 산업혁명 시대에 포스트휴먼적 존재들의 등장은 인간중심적인 근대 휴머니즘에서 탈피하여 인간 아닌 존재들과의 새로운 관계에 대한 성찰의 필요하다는 인식론적 변화를 야기했다. 이러한 성찰을 위해서 주변 세계를 공감하고 이해할 수 있는 포스트휴먼 감수성이 요구되며, 이러한 감수성 함양을 위해 포스트휴먼 시대를 사유하고 경험할 수 있는 미술작품 사례를 포스트휴머니즘 연구자인 브라이도티가 제시한 '동물-되기', '지구-되기', '기계-되기' 기준을 바탕으로 분석하여 제시하였다. 미술작품은 시대정신을 반영하고 있기에 포스트휴먼 시대를 성찰하고 체험해 볼 수 있는 텍스트라는 긍정적인 측면을 확인하였다. 본 연구는 포스트휴먼 감수성 함양을 위해 미술교육에서 활용할 수 있는 미술작품들을 제시하여 기초연구로서 의의가 있다.

• Journal of Applied Biological Chemistry
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• 제61권2호
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• pp.119-124
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• 2018

두충(Eucommia ulmoides Oliver)잎 아세톤 추출물의 in vitro 항암 및 항산화 활성을 조사하였다. 두충잎 아세톤 추출물의 수율은 $1.13{\pm}0.033%$ (w/w)이었고, 총 페놀성 화합물 함량은 $36.7{\pm}1.96mg$ gallic acid equivalents/g-추출물로 나타났다. 세포증식을 절반 억제하는 추출물의 농도인 $GI_{50}$값은 사람의 암세포인 비소세포폐암세포(A549)에서 $53.4{\mu}g/mL$, 결장암세포(SNU-C4)에서 $53.8{\mu}g/mL$ 및 자궁경부암세포(HeLa)에서 $88.3{\mu}g/mL$이었고, 사람의 정상세포인 배아 폐 상피세포(L132)에서는 $153.9{\mu}g/mL$로 나타났다. 두충잎 아세톤 추출물은 사람의 정상세포에는 낮은 독성을 나타내면서 농도에 비례하여 사람의 비소세포폐암세포(A549)와 결장암세포(SNU-C4)의 증식을 효과적으로 억제하였다. DPPH 유리라디칼을 절반 소거하는 추출물의 농도인 $EC_{50}$값은 2 mg/mL 정도로 높게 나타났고, 환원력의 $EC_{50}$값은 $275.8{\mu}g/mL$, 지질과산화를 절반 저해하는 농도인 $EC_{50}$값은 $257.9{\mu}g/mL$이었다. 유근피 아세톤 추출물은 농도에 비례하여 우수한 환원력 및 지질과산화 억제활성을 보여주었다.

• Archives of Pharmacal Research
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• 제23권1호
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• pp.42-45
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• 2000

6-Arylamino-7-halo-5,8-quinolinediones (4a-4k, 5a-5b) were tested for in vitro cytotoxicity against human solid tumor cell lines such as A 549 (non-small cell lung). SK-OV-3 (ovarian), SK-MEL-2 (melanoma), HCT-15 (colon) and XF 498 (CNS) by SRB assay. The arylamino-7-chloro-5,8-quinolinediones 4 were also evaluated for cyclin-dependent kinase (CDK2 and CDK4) inhibitory effect. Among them, the 5,8-quinolinediones 4a and 5a with 7-(4-fluorophenyl) amino group were found to be potent cytotoxic against HCT 15, SKOV-3 and XF 498, and the compounds 4f and 4i showed inhibitory activities for the CDK4.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2009년도 추계학술대회 논문집
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• pp.643-646
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• 2009

This study was conducted to simulate the influence of vibration associated with cycling on the body. In this simulation the human model that the riding on a bicycle which have suspension and non-suspension front forks was used. And to arouse impact two kind of bump, 50mm height of radical raised spot and 150mm height of slow raised spot, were used. The vertical displacement of head, the vertical acceleration of head and the torque of neck joint were analysed. The results say that the function of shock absorbing was grater when passing though a 50mm height of radical raised spot then a 150mm height of slow raised spot.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.717-722
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• 2003

A driving simulator is a computer-controlled tool to study an interface between a driver and vehicle response by enabling the driver to participate in judging vehicle characteristics. Using the driving simulator, human factor study, vehicle system development and other research can be effectively done under controllable, reproducible and non-dangerous conditions. An Adaptive Cruise Control (ACC) system is generally regarded as a system that can be achieved in the near future without the demanding infrastructure components and technologies. ACC system is an automatic vehicle following system with no human engagement in the longitudinal vehicle direction. And the influence of the driver is substantial in developing the system. Driving characteristic is very different according to the accident riskiness, gender, age and so on. In this research, experiments have been carried out to investigate driving characteristics with the ACC system, using a driving simulator. Participants are 21 male and 19 female. Driving characteristics such as preferred headway-time, lane keeping ability, eye direction, and head movement have been observed and compared between the driving with ACC and the driving without ACC.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 하계종합학술대회 논문집(4)
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• pp.222-225
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• 2000

Human frequently communicate non-linguistic information with gesture. So, we must develop efficient and fast gesture recognition algorithms for more natural human-computer interaction. However, it is difficult to recognize gesture automatically because human's body is three dimensional object with very complex structure. In this paper, we suggest a method which is able to detect key frames and frame changes, and to classify image sequence into some gesture groups. Gesture is classifiable according to moving part of body. First, we detect some frames that motion areas are changed abruptly and save those frames as key frames, and then use the frames to classify sequences. We symbolize each image of classified sequence using Principal Component Analysis(PCA) and clustering algorithm since it is better to use fewer components for representation of gestures. Symbols are used as the input symbols for the Hidden Markov Model(HMM) and recognized as a gesture with probability calculation.

• 한국안전학회지
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• 제32권1호
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• pp.33-40
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• 2017

This paper addresses the assessment methods used to evaluate the magnetic exposure of a human to ELF EMF (Extremely Low Frequency Electromagnetic Field) which is caused by the process of power delivery from 60 Hz commercial power. These days the main concern is primarily focused on the magnetic field. For the exposure assessment, both numerical studies and laboratory experiments were studied and the results of the two compared for methodological suitability. The numerical analyses employ the Impedance Method (IM), Boundary Element Method (BEM), and Finite Element Method (FEM) and the laboratory experiments used various human phantom models made with conductivities congruent to human organs and then exposed to uniform/non-uniform magnetic fields to produce eddy currents. Under these conditions a number of examples have been evaluated and the reliability assessed to present the pros and cons of each methodology.

• Journal of Periodontal and Implant Science
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• 제26권3호
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• pp.681-688
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• 1996

Periodontal regeneration requires the migration and proliferation of gingival fibroblasts and periodontal ligament cells. These cellular events are influenced and regulated by growth factors and some drugs. The purpose of this study is to examine the effect of Rhizoma coptidis and Centella asiatica extracts on human gingival fibroblasts. Gingival fibroblasts were primarily cultured from extracted premolar with non-periodontal diseases. Cells were cultured with ${\alpha}-MEM$ at $37^{\circ}C$, 5% $CO_2$, 100% humidity incubator for 2 or 3 days, as a measure of cell proliferation potential, it was examined that the DNA synthesis using $[^3H]-thyrnidine$ incorporation, the cell numbers (with or without dye), and cell viabilities. Rhizoma coptidis is increased the proliferation of gingival fibroblasts at concentration of $10^{-9}g/ml$, but Centella asiatica is decreased the proliferation at all concentrations. This study demonstrated that Rhizoma coptidis is a potential mitogen for human gingival fibroblasts in vitro, and we can expect the usefulness of this drug in periodontal regeneration.