• Title/Summary/Keyword: new health technology

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A New Method of Producing a Natural Antibacterial Peptide by Encapsulated Probiotics Internalized with Inulin Nanoparticles as Prebiotics

  • Cui, Lian-Hua;Yan, Chang-Guo;Li, Hui-Shan;Kim, Whee-Soo;Hong, Liang;Kang, Sang-Kee;Choi, Yun-Jaie;Cho, Chong-Su
    • Journal of Microbiology and Biotechnology
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    • v.28 no.4
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    • pp.510-519
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    • 2018
  • Synbiotics are a combination of probiotics and prebiotics, which lead to synergistic benefits in host welfare. Probiotics have been used as an alternative to antibiotics. Among the probiotics, Pediococcus acidilactici (PA) has shown excellent antimicrobial activity against Salmonella Gallinarum (SG) as a major poultry pathogen and has improved the production performances of animals. Inulin is widely used as a prebiotic for the improvement of animal health and growth. The main aim of this study was to investigate the antimicrobial activity of inulin nanoparticle (IN)-internalized PA encapsulated into alginate/chitosan/alginate (ACA) microcapsules (MCs) for future in vivo application. The prepared phthalyl INs (PINs) were characterized by DLS and FE-SEM. The contents of phthal groups in the PINs were estimated by $^1H-NMR$ measurement as 25.1 mol.-%. The sizes of the PINs measured by DLS were approximately 203 nm. Internalization into PA was confirmed by confocal microscopy and flow cytometry. The antimicrobial activity of PIN-internalized probiotics encapsulated into ACA MCs was measured by coculture antimicrobial assays on SG. PIN-internalized probiotics had a higher antimicrobial ability than that of ACA MCs loaded with PA/inulin or PA. Interestingly, when PINs were treated with PA and encapsulated into ACA MCs, as a natural antimicrobial peptide, pediocin was produced much more in the culture medium compared with other groups with inulin-loaded ACA MCs and PA encapsulated into ACA MCs.

Comparison of silkworm powder from 3 Bombyx mori varieties on alcohol metabolism in rats

  • Lee, Da-Young;Cho, Jae-Min;Yun, Sun-Mi;Hong, Kyung-Sook;Ji, Sang-Deok;Son, Jong-Gon;Kim, Eun-Hee
    • International Journal of Industrial Entomology and Biomaterials
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    • v.35 no.1
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    • pp.22-29
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    • 2017
  • Increased alcohol consumption is a burden on the world because it is associated with various health problems. However, the effects of silkworms on alcohol metabolism have not been studied yet. The hard-to-eat mature silkworms have become easier to ingest recently due to the development of technology, steam-lyophilising mature silkworm larvae. In this study, we investigated and compared the effects of SMSPs from three silkworm varieties, Baekokjam, Golden-silk and Yeonnokjam weaving white, golden, and light green cocoons on alcohol metabolism in vivo. Sprague-Dawley rats pretreated with three SMSPs (0.1 g/kg or 1 g/kg body weight) or normal diet (AIN-76A) for 2 weeks were subjected to intragastric administration of absolute ethanol (3 g/kg body weight, 3 h). Three SMSPs did not affect the final body weight and liver weight. All 3 SMSPs were effective to reduce the enzymes in alcohol metabolism, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), and liver damage and enzymes involved in liver damage, aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Among SMSP from 3 varieties of silkworm, preadministration of 1 g/kg Baekokjam SMSP showed the most effective suppressive effect on the activities of ADH, ALDH, AST and ALT. The Baekokjam SMSP contained higher amounts of beneficial amino acids than Golden-silk or Yeonnokjam SMSP. These results suggest that Baekokjam SMSP might be used as a new and promising candidate for improving alcohol metabolism and liver injury through promoting rapid alcohol metabolism.

Use of Defibrillator(AED) on Prehospital Cardiac Arrests (심정지 환자 이송 시 구급대원의 자동제세동기 사용현황)

  • Koh, Bong-Yeun;Choi, Yong-Chul;Lee, Jae-Youl
    • The Korean Journal of Emergency Medical Services
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    • v.10 no.2
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    • pp.53-62
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    • 2006
  • Purpose: There has been an increase in the number of prehospital cardiac arrests due to the increasing number of cardiovascular diseases and the increase in the average age of the population. We performed this study to identify the proper resuscitation technique and AED to be used to increase the survival rate in prehospital cardiac arrests. Methods: This studied 159 victims with prehospital cardiac arrests(VF or VT rhythm) by EMT's Reports from January to August, 2005. Results: 108 of 159 victims(67.9%) were shocked by AED. Eighty of 159 victims(50.9%) were recorded with AED shock in prehospital cardiac arrests. A number of shocks is averaged 2.19; 46.2% of one-shock and 86.1% of 1-3 shock. EMS first-tier response interval from time of dispatch to scene arrival was 5.88 minutes, from scene arrival to scene start was 7.36 minutes, from scene start to hospital admission was 9.91 minutes and from scene arrival to AED shock was 6.84 minutes. EMT provided advanced care to prehospital cardiac arrests: 97.5% in CPR, 10.1% in advanced airway management, 67.9% in AED shock. Conclusion: With the increase in cardiovascular disease and old age, the number of prehospital cardiac arrests has risen gradually. However, there were lack of CPR by bystander, defibrillation and advanced cardiac life support(ACLS) in prehospital stage. To improve the adequacy of basic life support and to increase the performance of ACLS, especially AED, we must create challenges to develop new protocols in prehospital care.

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Study on the character of the old aged pulsation (고령자의 맥상 특성에 대한 맥파분석적인 연구)

  • Kim, Gyeong-Cheol;Lee, Jeong-Won;Ryu, Gyeong-Ho;Gang, Hui-Jeong;Cho, Sang-Won;Park, Young-Jae;Kim, Min-Yong;Oh, Hwan-Sup;Park, Young-Bae
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.12 no.2
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    • pp.1-7
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    • 2008
  • Objectives: The basis research of aged people's healthcare technology is very important, because our nation goes into an aged society rapidly. Especially in traditional medicine, pulse shapes of aged people were supposed to weak and empty pulse until now, but any objective measurement and compare research do not taken. Methods and Results: Therefore in this study we design observation study to find characteristic of pulse between younger group (age $20{\sim}30$) and elder group (age $43{\sim}80$) in Busan area. We used 3-dimensional pulse analyzer '3-D MAC' (Daeyomedi Co., Ltd.). And major parameters for comparison are 1) pulse height (h1), 2) applied pressure, 3) pulse power (energy), 4) high pressure duration (w) and 5) R-AI. Conclusions: According to analysis result, elder people's pulse has more large value in pulse height, applied pressure and pulse power than younger's that. It reveals that elder people in modernized lifestyle has Yang symptoms as well Yin symptoms. Consequently we need new method to care elder people's health, and this means more important direction than old text book. From now on verification research with objective diagnosis device like 3-D MAC, must be activated to build of evidence in traditional medicine. Cause traditional medicine's spirit of care and prevention is suitable to care elder people's cardiac and cerebral vascular disease those are have close relation with elder people.

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A Study on the Regulation Improvement Measures for Activation of Internet of Things and Big Data Convergence (사물 인터넷과 빅데이터 융복합 활성화를 위한 규제 개선 방안에 관한 연구)

  • Kim, Ki-Bong;Cho, Han-Jin
    • Journal of the Korea Convergence Society
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    • v.8 no.5
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    • pp.29-35
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    • 2017
  • Korea has been showing a high interest in convergence centered on information and communication technologies for the past 10 years. However, with successful convergence of broadcasting and telecommunication sectors, successful convergence cases such as IPTV have been excluded. In some fields, The performance that citizens can experience is limited. In addition, the combination of the Internet of things and the big data shows that infinite data in the natural and social environment surrounding service users can be created and utilized to create better services. However, the division between departments and departments, And the limitations of policies and systems that can promote convergence of information and communication technologies. Therefore, in order to create new industries through the fusion of the Internet of things and big data, it is necessary to investigate what kind of inhibitory enzymes are present, to investigate the problems, to solve the problems, to develop technologies for activating the Internet and big data, And suggests ways to utilize the policy to promote convergence of related technologies.

The Development of Remote Monitoring System for Storm Overflow Chamber Device (우수토실 일체형 하수유량조절장치 원격관리시스템 개발)

  • Jeon, In-Jae;Kim, Ki-Bong
    • Journal of the Korea Convergence Society
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    • v.9 no.6
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    • pp.61-68
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    • 2018
  • This paper propose the remote monitoring system using LoRa networks about storm overflow chamber, which is a device designed to discharge rainwater directly to a sewage treatment plant when it reaches a certain amount of rainfall during precipitation. In this system, when the information produced by the sensor is transmitted to the LoRa network server and updated, the application server can automatically receive data through the implemented communication interface. The application server carries out management functions of storm overflow chamber devices and subscription information, collects measured flow rate and opening-closing information, and provides statistical information using the collected data. The android app performs a firebase-based notification function to prompt the user of malfunctioning of the storm overflow chamber device.

A Study on Factors Affecting the Intention of Using IoT-Based Fitness Tracker (IoT기반 피트니스 트래커의 사용의도에 영향을 미치는 요인에 관한 연구)

  • Cho, Dug Yun;Han, Kyeong Seok
    • Journal of Digital Contents Society
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    • v.19 no.9
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    • pp.1717-1726
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    • 2018
  • This study is for looking into Factors affecting the Intention of using about Fitness Tracker based on IoT by Flow Theory and UTAUT Model. The independent variables of the IoT-based fitness tracker have been selected as Challenge, Skill Factors used in the Flow experience theory and selected the personal characteristics of health perception, enjoyment, Social Influence, and Facilitating Conditions. In addition UTAUT theory was used as parameter of Performance Expectancy and Effort Expectancy and intention of Use behavior was selected as a dependent variable. For verifying research hypothesis, This study collected 126 surveys data and carried out a statistical analysis by Smart PLS. The result shows that new Flow Experience and Personal Characteristic Factors with key variables in the UTAUT Model affect significantly to Intention of using about Fitness Wearable environment based IoT.

A Proposal for Improving Techniques of GTS Utilization Based on WBAN (WBAN 기반의 GTS 채널 이용률 향상기법 제안)

  • Park, Joo-Hee;Jung, Won-Soo
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.10
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    • pp.73-81
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    • 2011
  • The WBAN(Wireless Body Area Network) technology is a short distance wireless network which provides each device's interactive communication by connecting devices inside and outside of body located within 3 meters. Standardization on the physical layer, data link layer, network layer and application layer is in progress by IEEE 802.15.6 TG BAN. The The WBAN servides consists of both medical and non-medical applications. The medical application service uses the sensor that transfer the periodic traffic and have different data rates. It uses GTS method to guarantee QoS. In this paper, a new method is proposed, which are suitable design for MAC Protocol. Firstly, MAC frame structure and a primitive based on the WBAN are proposed. Secondly, we proposed the GTS algorithm improved the channel utilization based on the WFQ(Weighted Fair Queuing). The proposed scheduling method is improved channel utilization compared with i-Game(Round Robin scheduling method).

Bio-Composite Materials Precursor to Chitosan in the Development of Electrochemical Sensors: A Critical Overview of Its use with Micro-Pollutants and Heavy Metals Detection

  • Sarikokba, Sarikokba;Tiwari, Diwakar;Prasad, Shailesh Kumar;Kim, Dong Jin;Choi, Suk Soon;Lee, Seung-Mok
    • Applied Chemistry for Engineering
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    • v.31 no.3
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    • pp.237-257
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    • 2020
  • The role of nano bio-composites precursor to chitosan are innumerable and are known for having different applications in various branches of physical sciences. The application to the sensor development is relatively new, where only few literature works are available to address the specific and critical analysis of nanocomposites in the subject area. The bio-composites are potential and having greater affinity towards the heavy metals and several micro-pollutants hence, perhaps are having wider implications in the low or even trace level detection of the pollutants. The nano-composites could show good selectivity and suitability for the detection of the pollutants as they are found in the complex matrix. However, the greater challenges are associated using the bio-composites, since the biomaterials are prone to be oxidized or reduced at an applied potential and found to be a hinderance for the detection of target pollutants. In addition, the materials could proceed with a series of electrochemical reactions, which could produce different by-products in analytical applications, resulting in several complex phenomena in electrochemical processes. Therefore, this review addresses critically various aspects of an evaluation of nano bio-composite materials in the electrochemical detection of heavy metals and micro-pollutants from aqueous solutions.

A study on standardization & completion of transfer consultation record for patients transferred to emergency medical center (응급의료센터로 전원된 환자의 진료의뢰서 표준화 및 충실도에 관한 연구)

  • Yoou, Soonkyu;Kim, Kwang Hwan;Cho, Hae Kyung
    • The Korean Journal of Emergency Medical Services
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    • v.5 no.1
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    • pp.177-198
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    • 2001
  • The purpose of this research which was conducted by surveying the transfer consultation records from 360 medical institutions such as general hospitals, hospitals, clinics to the Emergency Medical Center at E University Hospital for six months(Jan. 1, 2000 - Jun. 30, 2000) are to standardize & complete transfer consultation record of hospitals at the 1st & 2nd referral level and to give patients transferred emergency medical center medical information services on a better quality. The conclusions and suggestions from this study were summarized as follows; (1) Examing the distribution of the referral medical consultation(transfer) sheet type, surgery part local clinic sheet types were 34.4%, medical part local clinic sheet types were 26.7%, undifferentiated local clinic sheet types were 23.9% and hospital level sheet types were 15.0%. (2) The items of the transfer consultation records had been standardized more than 75% in the order of patient's name, date, doctor's name, diagnosis, patient's status, impressions. (3) That the degree of recording completion on these items is in the order of patient's name, date, diagnosis, impressions was revealed. (4) Because the standardization and the degree of recording completion are very low in the patient's gender, age, address, electronic recording system was needed for more perfect input of initial patient informations. (5) This standardizing & complete recording on examination and medication will prevent re-examination and abuse of medication for patients transferred emergency medical center. (6) EMT Transfer System should be fixed in all medical institute for the standardizing & complete recording on care period and departure time will give many emergency patients the proper treatments at the proper time. (7) It was revealed that developing new standardized transfer consultation record & using electronic recording system are needed. (8) The complete recording & Fast Track System were needed for higher rate of bed operation at emergency medical center and more hospital profit.

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