• 제목/요약/키워드: nerve sheath neoplasm

검색결과 17건 처리시간 0.025초

수지첨부에 발생한 신경초 점액종 (A Case of Nerve Sheath Myxoma on the Fingertip)

  • 이용석;김철한;강상규;탁민성
    • Archives of Plastic Surgery
    • /
    • 제37권1호
    • /
    • pp.67-70
    • /
    • 2010
  • Purpose: Nerve sheath myxoma is a rare cutaneous neoplasm originating from the peripheral nerve sheath and divided into three groups : myxoid, cellular and mixed type. There is a controversy on it's origin whether schwannian cell or perineurial differentiation, or anything else. Myxoid nerve sheath myxoma is asymptomatic, soft, papule or nodule in middle-age adults. We report a case of myxoid nerve sheath myxoma on the fingertip. Methods: A 53-year-old woman presented with a painful, $0.4{\times}0.4{\times}0.6\;cm $sized, corn shaped nodule on the left 3rd fingertip. We put into surgical excision and studied it by histopathologically and specific immnohistochemical stain. Results: The tumor has well defined nodules separated by thin fibrous connective tissue with abundant myxoid stroma and were positively stainded for S-100 protein, NSE and GFAP. After surgical treatment it was healed without recurrence. Conclusion: Nerve sheath myxoma is rare neoplasm and located mainly on face, but very rarely on the fingertip. We report a case of painful myxoid nerve sheath myxoma located on the 3rd fingertip.

Concurrence of Malignant Peripheral Nerve Sheath Tumor at the Site of Complex Regional Pain Syndrome Type 1 - A Case Report -

  • Jeong, Yeong Ho;Choi, Eun Joo;Nahm, Francis Sahngun
    • The Korean Journal of Pain
    • /
    • 제26권2호
    • /
    • pp.160-163
    • /
    • 2013
  • Malignant peripheral nerve sheath tumors (MPNSTs) are very rare sarcomas derived from various cells in the peripheral nerve sheath. Malignant peripheral nerve sheath tumors have a known association with neurofibromatosis type 1. Diagnosis of MPNSTs is difficult in patients with chronic pain, when MPNST occurs at an overlapping area of chronic pain. Therefore, the diagnosis can be missed unless clinicians pay attention to the possibility of this disease. Here in, we report a case of concurrent malignant peripheral nerve sheath tumor with complex regional pain syndrome type 1. A 44-year female patient, who was diagnosed with complex regional pain syndrome (CRPS) type 1 in her left ankle, visited our clinic because of aggravated pain. The cause of the aggravated pain was revealed as concurrent MPNST in the left common peroneal nerve territory, which overlapped the site of pain from CRPS.

Soft tissue sarcoma in neurofibromatosis type 1: A rare case of malignant peripheral nerve sheath tumor of the skin

  • Chung, Young Hun;Jang, Jin Woo;Cho, Jae Young
    • Archives of Plastic Surgery
    • /
    • 제47권1호
    • /
    • pp.92-96
    • /
    • 2020
  • Malignant peripheral nerve sheath tumor (MPNST) is a rare and often aggressive soft tissue sarcoma originating from the sheaths of peripheral nerves. Approximately 50% of MPNSTs occur in patients with neurofibromatosis (NF). These tumors often present as deep soft tissue lesions, arising from the nerve plexuses of the extremities or from the nerves extending from the trunk. They rarely occur in the skin, especially in patients with NF. Herein, we report our experience with an MPNST of the skin in a patient with NF.

복부에 발생한 악성 말초신경초종양 (Malignant Peripheral Nerve Sheath Tumor of Abdomen)

  • 소규섭;임영국;홍용택;김훈남
    • Archives of Plastic Surgery
    • /
    • 제38권6호
    • /
    • pp.886-889
    • /
    • 2011
  • Purpose: Malignant peripheral nerve sheath tumor without neurofibromatosis type 1 is very rare neoplasm. Development in the superficial soft tissue is exremely rare. Authors experienced one rare case of primary malignant peripheral nerve sheath tumor developed on abdomen. The clinical and histologic findings were described. Methods: An 83-year-old man visited hospital with an $11{\times}6.5{\times}4.5$ cm sized ulcerated and hemorrhagic mass on abdomen. The tumor was localized in abdominal skin and started growing 3 years ago. Results: Wide excision with safety margin of 2 cm and limberg flap was done. The postoperative biopsy revealed a malignant peripheral nerve sheath tumor. There was no evidence of recurrence of tumor for 16 months. Conclusion: Malignant peripheral nerve sheath tumor is an aggressive malignant tumor. An abrupt enlargement of size, ulceration and bleeding are suggestive of malignant chnages of the tumor. We recommand early wide excision with enough safety margin as treatment of malignant peripheral nerve sheath tumor.

구개골에 발생한 악성 Peripheral Nerve Sheath Tumor의 증례보고 (MALIGNANT PERIPHERAL NERVE SHEATH TUMOR ON PALATE: A CASE REPORT)

  • 권민수;이현상;김현창;고승오;신효근
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • 제30권3호
    • /
    • pp.228-233
    • /
    • 2004
  • Summary: The malignant peripheral nerve sheath tumor(MPNST) is an aggressive neoplasm and can either arise independently or result from malignant change in preexisting neurofibromatosis (von Recklinghausen's disease). Its histologic characteristics remain controversial, but currently it is believed that the schwann cell is the origin of the peripheral nerve sheath tumors. MPNST is an uncommon neoplasm of the head and neck region, and its presentation in the oral cavity is quite rare. In this study, we report a patient with a rare case of a MPNST involving the maxilla. A case report: A 29-year-old female presented with a chief complaint of painless swelling with bleeding tendency on the left maxillary tuberosity area 2 months ago. Clinical examination showed a $5.0{\times}3.0cm^2$ sized, indurative swelling on the site. Conventional radiographs showed a relatively well-defined soft tissue mass involving the left maxillary sinus, and destruction of the anterior, posterolateral walls of the left maxillary sinus. Subtotal maxillectomy and split-thickness skin graft from thigh were undertaken. In histochemical and immunohistochemical studies, the specimen revealed positive reactivities to Vimentin and S-100 protein. Final diagnosis was made as MPNST.

Superficial malignant peripheral nerve sheath tumor from recurrent neurofibroma in the abdominal wall of a patient without neurofibromatosis type 1

  • Jung, Chang Yeon;Bae, Jung Min;Choi, Joon Hyuk;Jung, Ki Hoon
    • Journal of Yeungnam Medical Science
    • /
    • 제36권1호
    • /
    • pp.63-66
    • /
    • 2019
  • Malignant peripheral nerve sheath tumor (MPNST) is rare, accounting for 5-10% of all soft tissue sarcomas. MPNST is characteristically aggressive and has a poor prognosis. Fifty percent of patients with MPNST have neurofibromatosis type 1 (NF1). NF-associated MPNST occurs more often at younger ages than sporadic MPNST, but the survival difference is controversial. Superficial MPNST from a recurrent neurofibroma is extremely rare and only a limited number of cases have been reported in the literature. Herein, we report an unusual case of superficial MPNST from a recurrent neurofibroma in a patient without NF1.

흉벽에 발생한 악성 신경초종 -1례 보고- (Malignant Schwannoma on the Right Chest Wall -1 Case Report-)

  • 황의두;황경환
    • Journal of Chest Surgery
    • /
    • 제30권10호
    • /
    • pp.1051-1053
    • /
    • 1997
  • 악성신경초종은 Schwan cell 또는 신경초 세포(nerve sheath cell)에서 발생하는 아주 드문 종양으로 빈번히 신경섬유종증(Von Rechlinghausen's disease)과 연관되어 있다. 환자는 64세 남자로 우측 가슴에 내원 2개월전부터 있던 무통성 종물을 주소로 내원하였으며 신경섬유종 증과의 동반은 없었다 전산화 단층촬영상 종물의 크기는 6 $\times$ 6 cm였으며, 11번 늑골과 횡경막을 침범하였 고 우신을 앞쪽으로 밀고 있었다. 본 교실에서는 흉벽에 발생한 악성신경초종을 경험하였기에 문헌고찰과 함께 보고한다.

  • PDF

폐정맥의 원발성 악성 말초신경초종: 증례 보고 (Primary Malignant Peripheral Nerve Sheath Tumor of the Pulmonary Vein: A Case Report)

  • 우현;권혜영;김진환;김성수;박형규;이연주;박재형
    • 대한영상의학회지
    • /
    • 제84권6호
    • /
    • pp.1384-1390
    • /
    • 2023
  • 심장과 대혈관 기원의 원발성 종괴는 매우 드물다. 그중에서도 악성 말초신경초종은 더 드물게 보고되었다. 76세 남성에서 발견된 흉수의 원인 평가를 위해 시행한 조영증강 컴퓨터단층촬영에서 우폐정맥과 좌심방을 침범하는 저음영의 종괴가 발견되었고 초음파상 우폐정맥에서 기인한 종괴로 의심되었다. 종괴는 수술적 절제를 통해 폐정맥 기원의 악성 말초신경초종으로 최종 진단되었다. 저자들은 국내에서 보고된 바가 없는 드문 증례인 폐정맥 기원의 원발성 악성 말초신경초종을 보고하고, 종괴가 폐정맥 기원임을 시사하는 영상의학적 소견에 대해 고찰하고자 한다.

부인강에서 발생한 설하신경의 신경초종 1례 (A Case of Parapharyngeal Neurilemmoma Arising from Hypoglossal Nerve)

  • 이성욱;은상용;박성준;이상훈
    • 대한두경부종양학회지
    • /
    • 제16권1호
    • /
    • pp.69-72
    • /
    • 2000
  • The neurilemmoma is a relatively uncommon benign neoplasm which is known to be originated from the schwann sheath of the nerve fiber. Parapharyngeal neurilemmomas may originate from any nerve traversing this space, but the vast majority arise from the vagus nerve and sympathetic chain. The neurilemmomas arising from the extracranial portion of the hypoglossal nerve are extremely rare. To our knowledge, the case we present is the ninth one to be reported occurring in the parapharyngeal space. Recently we experienced a case of parapharyngeal neurilemmoma arising from the hypoglossal nerve and so we report our case with a brief review of literatures.

  • PDF

두경부 말초신경초종의 임상적 고찰 (A Clinical Analysis of Peripheral Nerve Sheath Tumors in the Head and Neck Region)

  • 강석영;신명철;유한석;이용섭;박철원;태경
    • 대한두경부종양학회지
    • /
    • 제24권2호
    • /
    • pp.174-178
    • /
    • 2008
  • Background and Objectives:Peripheral nerve sheath tumors(PNSTs) are uncommon neoplasm in the head and neck region. The treatment of PNSTs is surgical removal, but excision cause neurologic complications. This study was performed to evaluate the proper diagnosis and treatment of PNSTs with our experiences. Subjects and Method:During the period from October 1994 to July 2007, 58 patients were diagonised with PNSTs in head and neck region. We reviewed medical records and imaging study retrospectively. Result:95%(55/58) of the PNSTs in head and neck were benign;5%(3/58) were malignant peripheralnerve sheath tumors(MPNSTs). 63%(37/58) were neurilemoma, 20%(17/20) were neurofibroma, 2%(1/58) was perineuroma. 55 patients underwent surgery. 80%(45/55) of cases were treated with excision. Enucleation was performed in 7(14%) patients. All cases of benign neurogenic tumors showed no recurrence. Among 3 of MPNSTs 2 patients were Von Recklinghausen’s disease and expired with regional recurrence and lung metastasis. Conclusion:The benign PNSTs can be treated with enucleation if possible and observation can be another choice to minimize neurologic sequele.