Browse > Article

MALIGNANT PERIPHERAL NERVE SHEATH TUMOR ON PALATE: A CASE REPORT  

Kwon, Min-Su (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University)
Lee, Hyun-Sang (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University)
Kim, Hyun-Chang (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University)
Ko, Seung-O (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University)
Shin, Hyo-Keun (Department of Oral & Maxillofacial Surgery, School of Dentistry, Institute of Oral Bio-Science, Chonbuk National University)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.30, no.3, 2004 , pp. 228-233 More about this Journal
Abstract
Summary: The malignant peripheral nerve sheath tumor(MPNST) is an aggressive neoplasm and can either arise independently or result from malignant change in preexisting neurofibromatosis (von Recklinghausen's disease). Its histologic characteristics remain controversial, but currently it is believed that the schwann cell is the origin of the peripheral nerve sheath tumors. MPNST is an uncommon neoplasm of the head and neck region, and its presentation in the oral cavity is quite rare. In this study, we report a patient with a rare case of a MPNST involving the maxilla. A case report: A 29-year-old female presented with a chief complaint of painless swelling with bleeding tendency on the left maxillary tuberosity area 2 months ago. Clinical examination showed a $5.0{\times}3.0cm^2$ sized, indurative swelling on the site. Conventional radiographs showed a relatively well-defined soft tissue mass involving the left maxillary sinus, and destruction of the anterior, posterolateral walls of the left maxillary sinus. Subtotal maxillectomy and split-thickness skin graft from thigh were undertaken. In histochemical and immunohistochemical studies, the specimen revealed positive reactivities to Vimentin and S-100 protein. Final diagnosis was made as MPNST.
Keywords
Malignant peripheral nerve sheath tumor; MPNST; Subtotal maxillectomy;
Citations & Related Records
연도 인용수 순위
  • Reference
1 MJ Bullock, YC Bedard, RS Bell, R Kandel : Intraosseous Malignant Peripheral Nerve Sheath Tumor. Report of a Case and Review of the Literature. Arch Pathol Lab Med 1995;119:367-370
2 A Piatelli, A Angelone, G Pizzicannella, M Piatelli : Malignant schwannoma of the tongue: Report of a Case and Review of the literature. Acta Stomatol Belg 1984;81:213-225
3 AT Al-Otieschan, MB Manohar, K Gangopadhyay, A Tulbah : Cellular Schwannoma of the Paranasal Sinuses: Initial Report of a Case. ENT J 2002;81:281-284
4 MR Wick, PE Swanson, BW Scheithauer, KC Manivel : Malignant Peripheral Nerve Sheath Tumor. An Immunohistochemical Study of 62 Cases. Am J Clin Pathol 1987;87:425-433
5 AG John, KP Minu, AB Henry, JW Michael, KDG Tapas : Soft Tissue Sarcomas of the Adult Head and Neck. Cancer 1985;56:820-824   DOI   ScienceOn
6 F Enzinger, SW Weiss : Malignant Tumors of Peripheral Nerves. in: Soft Tissue Tumors. 2nd Ed. Mosby, St. Louis 1988
7 PP Sordillo, L Helson, SI Hajdu, GB Magill, C Kosloff, RB Golbey, EJ Beattie : Malignant Schwannoma-Clinical Characteristics, Survival, and Response to Therapy. Cancer 1981;47:2503-2509   DOI   ScienceOn
8 CJ Lyons, AA McNab, A Garner, JE Wright : Orbital Malignant Peripheral Nerve Sheath Tumors. Br J Ophthalmo 1989;73:731-738   DOI   ScienceOn
9 M MacCollin, W Woodfin, D Kronn, MP Short : Schwannomatosis: a Clinical and Pathologic Study. Neurology 1996;46:1072-1079   DOI
10 HL Hammon & RG Calderwood : Malignant Peripheral Nerve Sheath Tumors of the Oral Cavity. Review of the literature and Report of a case. Oral Surg Oral Med & Oral Pathol 1969;28:97-105   DOI   ScienceOn
11 C Colmenero, T Rivers, M Patron, I Sierra, C Gamallo : Maxillofacial Malignant Peripheral Nerve Sheath Tumors. J Craniomaxillofac Surg 1991;19:40-46   DOI
12 BS Ducatman, BW Scheithauer, DG Piepgras, HM Reiman, DM Ilstrup : Malignant Peripheral Nerve Sheath Tumors. A Clinicopathologic Study of 120 Cases. Cancer 1986;57:2006-2021   DOI   ScienceOn
13 M DiCerbo, JJ Sciubba, WC Sordill, DM DeLuke : Malignant Schwannoma of the Palate: a Case Report and Review of the Literature. J Oral Maxillofac Surg 1992;50:1217-1221   DOI   ScienceOn
14 K Leroy, V Dumas, N Martin-Garcia, MC Falzone, MC Voisin, J Wechsler, J Revuz, A Creange, E Levy, L Lantieri, J Zeller, P Wolkenstein : Malignant Peripheral Nerve Sheath Tumors Associated with Neurofibromatosis Type 1. Arch Dermatol 2001;137:908-913
15 RS Weber, RS Benjamin, LJ Peters, JY Ro, O Achon, H Goepfert : Soft Tissue Sarcomas of the Head and Neck in Adolescents and Adults. Am J Surg 1986;152:386-392   DOI   ScienceOn
16 H Matsunou, T Shimoda, S Kakimoto, H Yamashita, E Ishikawa, M Mukai : Histopathologic and Immunohistochemical Study of Malignant Tumors of Peripheral Nerve Sheath (Malignant Schwannoma). Cancer 1985;56:2269-2279   DOI   ScienceOn