A Clinical Analysis of Peripheral Nerve Sheath Tumors in the Head and Neck Region

두경부 말초신경초종의 임상적 고찰

  • Kang, Seok-Young (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University) ;
  • Shin, Myung-Chul (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University) ;
  • Yoo, Han-Seok (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University) ;
  • Lee, Yong-Seop (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University) ;
  • Park, Chul-Won (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University) ;
  • Tae, Kyung (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University)
  • 강석영 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 신명철 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 유한석 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 이용섭 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 박철원 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 태경 (한양대학교 의과대학 이비인후-두경부외과학교실)
  • Published : 2008.11.30

Abstract

Background and Objectives:Peripheral nerve sheath tumors(PNSTs) are uncommon neoplasm in the head and neck region. The treatment of PNSTs is surgical removal, but excision cause neurologic complications. This study was performed to evaluate the proper diagnosis and treatment of PNSTs with our experiences. Subjects and Method:During the period from October 1994 to July 2007, 58 patients were diagonised with PNSTs in head and neck region. We reviewed medical records and imaging study retrospectively. Result:95%(55/58) of the PNSTs in head and neck were benign;5%(3/58) were malignant peripheralnerve sheath tumors(MPNSTs). 63%(37/58) were neurilemoma, 20%(17/20) were neurofibroma, 2%(1/58) was perineuroma. 55 patients underwent surgery. 80%(45/55) of cases were treated with excision. Enucleation was performed in 7(14%) patients. All cases of benign neurogenic tumors showed no recurrence. Among 3 of MPNSTs 2 patients were Von Recklinghausen’s disease and expired with regional recurrence and lung metastasis. Conclusion:The benign PNSTs can be treated with enucleation if possible and observation can be another choice to minimize neurologic sequele.

Keywords

References

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