• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2001년도 추계학술발표대회
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• pp.815-818
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• 2001

수계 미생물의 세포 농도 정도를 DST와 spectrophotometer를 이용하여 간편하고 빠르게 측정할 수가 있었다. 기존의 MPN와 MF의 방법은 노동집약적이며 false positive나 false negative의 확률이 높고 검출 시간도 하루이상 소요되는 단점이 있었다. 그러나, 세포 성장거동과 DST의 원리를 웅용하여 간편한 검출 시스템을 정량적으로 기술함으로써 쉽고 빠르게 수계 미생물의 농도를 측정하는 방법을 제시하였다.

• 대한수의학회지
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• 제32권4호
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• pp.579-583
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• 1992

A total of 113 Staphylococcus hyicus subsp. hyicus which had been isolated from healthy and diseased pigs were examined for their ability to produce staphylococcins. For selection of staphylococcin indicator strains, 80 strains were randomly selected from 113 strains, and were tested as indicator and as donator. The 8 indicators were chosen and used to type all of the strains. The ability to produce staphylococcin could be demonstrated in 43 strains (38.1%) of 113 Staph hyicus subsp. hyicus. The frequency of activity was higher in diseased pig strains (44.4%) than in healthy pig strains(36.8%). 43 staphylococcin producer strains were differentiated into 10 reaction types. The inhibitory effects of the staphylococcin (N27 and R 3) on other staphylococci differed by the staphylococcal species tested. All the gram-negative species were completely resistant to the three producing strains.

• 감성과학
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• 제2권1호
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• pp.1-25
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• 1999

The differentiation of emotions by means of psychophysiological measures has been only moderately successful so far. A major reason for this dilemma may be the lack of appropriate neurophysiological modeling for the various autonomic nervous system based measures being used in emotion research. The aim of the present article is to provide such a neurophysiological background for electrodermal activity which has been frequently used as an indicator of emotional processes. First, the literature is reviewd with respect to the usability of electrodermal measures as an indicators of emotion. second, the neurophysilogical sources of electrodermal phenomena in general are described. Electrodermal activity has different origins in the central nervous system, a limbic-hypothalamic source that dominates during negative emotions as opposed to a premotor and basal ganglia source being predominantly active during positive emotions. Panksepp's model of four basic emotive systems is adopted for demonstrating subcortical structures and pathways possibly involved in the elicitation of both kinds of electrodermal activity in comparison with cardiovascular in dicators of emotional processes.

• Journal of Gastric Cancer
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• 제10권2호
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• pp.55-62
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• 2010

Purpose: We evaluated the clinicopathological charicterics and prognostic impacts of lymphatic vessel invasion in gastric cancer without lymph node involvement. Materials and Methods: Among 1,795 patients who underwent gastric surgery with gastric cancer at the department of surgery, Hanyang university college of medicine from June 1992 to March 2009, we retrospectively evaluated 890 patients with lymph node negative gastric cancer. Results: The lymphatic vessel invasion correlated significantly with tumor stage, age, tumor size, perineural invasion and operation method. The survival rates were only significantly different between the patients with and without lymphatic vessel invasion in patients with stage Ia (P=0.036). Univariate and multivariate analysis demonstrated that blood vessel invasion and preoperative serum CEA level were significant factor influencing the survival rate in lymph node negative gastric cancer patients with lymphatic invasion. Conclusions: In patients with lymph node negative gastric cancer, the survival rate is significantly lower in those with lymphatic vessel invasion than in those without. Especially, in patients with stage Ia gastric cancer, the survival rates is significantly different between those with and those without lymphatic vessel invasion. Blood vessel invasion and preoperative serum CEA level is an adverse prognostic indicator in patients with stage Ia gastric cancer with lymphatic invasion. Thus we should consider further adjuvant therapies in case of need and need to show more concern to identify gastric cancer patients early at risk for recurrence.

• The Korean Journal of Pain
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• 제34권1호
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• pp.94-105
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• 2021

Background: Many patients with complex regional pain syndrome (CRPS) have been known to be at risk of suicide, due to severe pain and its comorbid conditions. The risk of suicide may be associated with affective instability, which is an indicator of emotional dysregulation. Particularly, unstable shifts in negative emotions are difficult to cope with, which may result in individuals feeling uncontrollable, hopeless, and entrapped. This study aimed to examine the role of affective instability in the relationship between pain intensity and suicide risk (suicidal ideation and impulsivity) in patients with CRPS, by employing a daily diary. Methods: Twenty-three patients registered at the CRPS Association in Korea were asked to complete a day-to-day routine for 15 days, followed by a diary composed of pain intensity, suicidal ideation, impulsivity, and positive and negative affects. Results: Results showed that the interactions between negative affective instability and daily pain intensity were statistically significant on daily suicidal ideation (coefficient = 0.41, t (21) = 2.56, P < 0.050) and daily impulsiveness (coefficient = 1.20, t (19) = 3.35, P < 0.010). However, those between positive affective instability and daily pain intensity were not. Conclusions: This study is the first attempt to investigate the role of affective instability on the relationship between daily pain intensity and daily suicide risk in patients with CRPS. Our findings suggest that health professionals pay considerable attention to the instability of negative affects when assessing and managing patients with CRPS at risk of suicide.

• 재활간호학회지
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• 제9권2호
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• pp.134-144
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• 2006

Purpose: This study was done to investigate correlations among Health Promoting Lifestyles, Health Risk Indicators, Activities of Daily Living, and Depression of the in-house stroke patients. Method: The subjects were 58 in-house stroke patients in a health center and two welfare centers. Data was collected using questionnaires and measuring health risk indicators such as blood pressure, total cholesterol, triglyceride, blood sugar, body fat rate. Data was analyzed using descriptive statistics, t-test, ANOVA, and Pearson correlation coefficients. Result: The health promoting lifestyle performance showed a significant negative correlation with health risk indicators and depression. There was a significant negative correlation between activities of daily living and depression. Conclusion: Health promoting lifestyle which focus on regular physical check-up, medication, diet management, exercise, smoking cessation, drinking abstinence, and stress management should be developed to improve health risk indicator and depression of the in-house stroke patients.

• 기술혁신연구
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• 제19권1호
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• pp.55-78
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• 2011

과학기술의 사회적 파급력이 갈수록 높아지고 있는 현대에 기술영향평가가 갖는 의미는 작지 않다. 특히 행정부에 의하여 제도화되어 수행되는 우리나라의 공식적 기술영향평가는 그 결과를 직접 과학기술 정책에 반영하도록 되어 있기 때문에 과학기술에 의한 부정적 효과나 사회적 논란에 미리 대비할 수 있게 해주는 장치가 된다. 사회적 평가를 중요시하는 기술영향평가 자체의 특징이나 매년 한 개 정도의 기술만을 대상으로 하는 제도적 기술영향평가의 운영 형태, 기술의 특징에 따라서 결정되는 평가의 내용 및 방법 등을 고려했을 때 대상기술의 선정은 다양한 관점을 고려하여 신중하게 이뤄져야 할 것이다. 그러나 지금까지 진행된 기술영향평가에서 대상기술의 선정 방식은 다양한 의견을 반영하지 못 하거나, 기술영향평가에 대한 이해보다는 정성적 토론 및 투표에 의하여 도출되는 경우가 많았다. 이 논문에서는 요인분석을 통하여 기술영향평가의 대상기술을 선정함에 있어 고려해야 할 지표들을 개발하였다. 개발된 지표는 사회적 합의의 필요성, 사회/문화적 파급효과 등 5가지로 구성되어 있으며, 각 지표들에 대한 가중치 역시 AHP 방법을 이용하여 도출하였다. 개발된 지표와 가중치를 이용하여 실제 어떻게 적용될 수 있는지를 예시를 통해 보여주었으며, 제도적 기술영향평가에 직접 적용할 때 고려해야 할 제언 또한 도출하였다. 향후 본 연구에서 도출된 지표를 활용함으로써, 제도적 기술영향평가에 적절한 대상기술을 선정할 수 있을 것이며 그를 통하여 기술영향평가 결과의 활용이 사회적 정책적으로 강화될 수 있을 것으로 전망된다.

• 한국게임학회 논문지
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• 제17권6호
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• pp.189-198
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• 2017

본 연구의 목적은 흡연을 주제로 하는 기능성 게임에 따른 흡연 태도의 차이점을 규명하고, 흡연태도와 심리생리학적인 변인 간의 영향관계를 살펴본 뒤, 금연 활동에 도움이 될 수 있는지를 알아보는데 목적이 있다. 이를 위해 흡연에 대한 부정적 태도를 종속변인으로 설정하고 부정적 태도에 영향을 미칠 수 있는 심리적 저항, 심리적 디스트레스, 뇌파(Left Brain ${\theta}$, Right Brain ${\theta}$)를 독립변인으로 설정하여 회귀분석을 실시하였다. 연구결과 흡연에 대한 부정적 태도에 심리적 저항은 부정적으로 영향을 미치고 있었으며, 심리적 디스트레스는 정적으로 영향을 미치고 있었다. 그리고 ${\theta}$파의 경우 좌뇌에서는 부정적으로 영향을 미치고 있었고, 우뇌에서는 정적으로 영향을 미치고 있음이 확인되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권8호
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• pp.3735-3737
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• 2016

Background: The purpose of this study is to evaluate if there is a relation between platelet: lymphocyte ratio (PLR) and neutrophil lymphocyte ratio (NLR) values and tumour histology and spread in bladder cancer cases. Materials and Methods: Bladder cancer patients undergoing TUR-M operation, with histopathologically verified diagnosis, followed-up and treated at the Private Medical Park Gaziantep Hospital between 2010 and 2015, have were included in the study. NLR and PLR values were calculated using complete blood count data obtained at the first presentation. Results: A total of 99 patients were included in the study, 7 (7.1%) women and 92 men (92.9%). When NLR was used as the indicator of systemic inflammatory response (SIR), it was determined that, 52 (52.5%) of the patients were SIR negative and 47 (47.5%) SIR positive. No significant relation could be detected between NLR and tumour grade and muscle invasion (p=0.948, p=0.480). When PLR was used as SIR indicator, it was determined that 71 (71.7%) of the patients were found as negative and 28 (28.3%) as positive. No significant relation could be detected between PLR and tumour grade and muscle invasion (p=0.651, p=0.494). Conclusions: In our study we did not detected a relation between tumour histological behavior and PLR and NLR in bladder cancer. However, NLR and PLR are easily calculated, accessible, inexpensive and simple-to-use laboratory data from whole blood counts.

• 한국융합학회논문지
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• 제8권10호
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• pp.231-238
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• 2017

본 연구에서는 융합 시대를 맞이하여 국내 수출에 영향을 미치는 지표들을 찾고자 금리와 원/달러, 원/엔, 원/위안화를 선정하였다. 지난 2000년 1월 이후 210개월 동안 상관관계와 회귀분석, 지표분석, 모형분석 등을 시도하였다. 분석결과 상관분석에서는 수출이 원/달러, 원/위안화, 원/엔 환율과 음(-)의 관계를 보여 서로 방향성이 다르게 나타났다. 회귀분석에서는 수출에 대해 금리와 원/달러만 통계적으로 유의하게 나타났다. Coefficient가 금리는 양(+)의 값으로, 원/달러는 음(-)의 값으로 산출되었다. 원/달러 하락이 수출 증가에 긍정적으로 작용하는 것으로 추정되었다. 본 연구에서 원/달러 환율이 하락하면 수출이 증가하는 것으로 나타나 기존 선행연구와 다르게 나타났다. 그래서 시간차에 의한 선후행 관계를 다시 살펴볼 필요성이 제기되었다. 우리나라는 수출에 대한 의존도가 높은 편이다. 따라서 수출 증가를 위해 수출에 영향을 미치는 지표들에 관한 연구가 지속되어야 할 것이다.