• YAKHAK HOEJI
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• v.15 no.1
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• pp.1-7
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• 1971

When a large quantity of insoluble drugs was added into a solution containing a small amount of soluble drugs, the latter was adsorbed to the former. Their adsorption was expected to alter the drug activity. Berberine hydrochloride (BH) was selected as a soluble drug and tested with frequently combined insoluble drugs and antacids for their adsorption phenomena in prufied water, gastric and intetinal fluid test solutions, respectively. The adsorption isotherms of kaolin and natural anuminum silicate with BH in the three media fitted the Langmuir (LM) equation, and that of talc in purified water and gastric fluid fitted it, but in intestinal fluid it fitted the Freudlich quation. The adsorption isotherm of aluminum hydroxide fitted the LM equation only in intestinal fluid. The degree of adsorption of BH in purified water and gastric fluid is in the following order: magnesium trisilicate, kaolin, natural aluminum silicate and talc; in intestinal fluid: magnesium trisilicate, kaolin, talc, natural aluminum silicate and aluminum hydroxide. Magnesium stearate did not adsorb BH.

• International Commerce and Information Review
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• v.1 no.1
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• pp.87-105
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• 1999

A objective of this study is to examine a commercial practices and analyze a trade environment for a successful launch of Indonesian market. In general, Indonesian trade environment is composed of a natural environment, religious peculiarity, history and politic, an economic prospect. In order to understand a commercial practice exactly and then be possible a favorable business achievement, a natural character, a mode of living, custom of a meal and invitation, custom of gift, religious taboo, a human relationship, commercial power, a tendency of product preference should be recognized. The results of the study indicate mostly that even though an excellent brand image, a good Quality and an efficient sales network are a basic factor for making of a successful business. However practically it is more important to understand a business custom and a natural character of Indonesian. Because business is made up of through relation between human being eventually.

• Journal of Contemporary Eastern Asia
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• v.15 no.2
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• pp.177-190
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• 2016

One of the main objectives of this paper is to provide insight to understand the effect of natural disasters on local government finance. That is, to analyze local governments' sales tax revenues after Hurricane Ike. Three Texas cities are examined: League City, Pearland, and Sugarland. Based on data collected from the Texas Comptroller's Office and the US Census, we found local governments experience a short-term increase in sales tax revenues and a long-term decline after the hurricane strike the region. On average, a major hurricane has a two-year impact on local government economy. The findings are essential for practitioners because in order to have a prosperous recovery after natural disasters, public managers have to prepare financially for short term changes in their sales tax revenues.

• Proceedings of the KIEE Conference
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• 1998.07g
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• pp.2530-2532
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• 1998

Micro gold electroplating structure is fabricated by surface micromachining process. The made structure is clamped-clamped beam and its 1st natural frequency is measured by resonance method. In order to find residual stress, first natural frequency of beam which has tensile stress inside is analysed using Rayleigh's method. Elastic modulus and residual stress are estimated from the measured natural frequency.

• Journal of the Optical Society of Korea
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• v.19 no.2
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• pp.199-205
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• 2015

We investigated the effects of the thickness and doping concentration in p- and n-type poly-Si layers on the performance of a solar cell based on a carbon fiber in order to improve the energy conversion efficiency of the cell. The short-circuit current density and open-circuit voltage of the carbon fiber-based solar cell were significantly influenced by the thickness and doping concentration in the p- and n-type poly-Si layers. The solar cell efficiency was successfully enhanced to ~10.5%.

• Journal of the Korea Safety Management & Science
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• v.13 no.1
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• pp.1-9
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• 2011

It is a significant issue for several country including Korea, where the natural and the weather conditions are severe, to keep the safety against disasters which occur frequently every year, especially in urban region crowded with population. In order to implement suitable and effective measures against various disasters in such area, development of method for evaluation of disaster prevention performance based on various disaster risks and effective disaster damage mitigation technologies is independable. In this paper, methods for hazard evaluation, vulnerability evaluation and loss evaluation, and damage technologies are proposed targetting man-made disaster and natural one like flood, earthquake and tsunami and so on. The method proposed in this paper is based on the research of USA and Japan for man-made disaster and natural disaster. The proposed method will be developed in detail in four years during research period funded by government.

• Journal of Korean Association for Spatial Structures
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• v.17 no.1
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• pp.93-100
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• 2017

With increasing number construction of high-rise building which has about 40 to 60 floors there have been many kinds of problem which related with usage from vibration. To predict response acceleration, it is important to assess correct natural frequency. However, due to the noise of MEMS sensor, it is difficult to measure dynamic characteristic such as natural frequency when measuring ambient vibration using MEMS sensor within cell phone. Therefore, a comparative analysis on vibration measuring applications was performed after measuring ambient vibration of 2 skyscrappers which have height between 133.5~244.3m that are located in Seoul and Observation tower using I-jishin APP with noise reduction function of MEMS sensor in order to verify the effectiveness of low noise type vibration measurement APP.

• Korean Journal of Plant Resources
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• v.5 no.2
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• pp.95-103
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• 1992

Present anticancer drugs in the clinical side have not showed a conclusive effect of the chemotherapy for cancer patients. In order to find much more efficient antitumor agents fromnatural resources, various screening methods vivo and in vitro have been developed by manyresearchers. The intention of this paper is to provide an outline of some background on the tumorsystem in drug development of natural products, to review some screening programs for theevaluation of antitumor activity and to introduce the practical procedures of some antitumorscreening methods in vivo and in vitro. At the end of this paper, the current literatures related toantitumor natural products from higher plants at our laboratory are described.Key words'anticancer drugs, screening methods.

• YAKHAK HOEJI
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• v.28 no.4
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• pp.231-235
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• 1984

Active principles for the anti-fatigue activity of Panax ginseng were studied in mice using the swimming performance method. Ginseng water extract maximized the prolongation of swimming time 18 hours after administration. The potencies of anti-fatigue activities were found as in the order of ether soluble fraction and butanol soluble fraction as those of antioxidant activities previously determined. The anti-oxidant components, maltol, salicylic acid and vanillic acid isolated from the ether soluble fraction of Panax ginseng strongly exhibited the antifatigue activities, where as highly purified crystalline ginsenoside $4Rb_1$, Re and $4Rg_1$ did not.

• Development and Reproduction
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• v.21 no.4
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• pp.449-456
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• 2017

The germline stem cells of the Drosophila ovary continuously produce eggs throughout the life-span. Intricate regulation of stemness and differentiation is critical to this continuous production. The translational regulator Nos is an intrinsic factor that is required for maintenance of stemness in germline stem cells. Nos expression is reduced in differentiating cells at the post-transcriptional level by diverse translational regulators. However, molecular mechanisms underlying Nos repression are not completely understood. Through three distinct protein-protein interaction experiments, we identified specific molecular interactions between translational regulators involved in Nos repression. Our findings suggest a model in which protein complexes assemble on the 3' untranslated region of Nos mRNA in order to regulate Nos expression at the post-transcriptional level.