• Journal of Life Science
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• v.23 no.11
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• pp.1388-1396
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• 2013

This study used an S-180 cell-injected mouse model to evaluate the antitumor effects of the acute and subacute toxicity of Keumsa (Phellinus linteus) extract intravenously administrated in ICR mice. When administered intravenously (31.3-250 mg/kg body weight), Keumsa (Phellinus linteus) extract significantly inhibited the growth of the solid tumor cell. The antitumor activity of Keumsa (Phellinus linteus) extract increased in a dose-dependent manner. The highest dose (250 mg/kg body weight) was highly effective, reducing tumor formation by 42.7% compared with the control group. In the acute toxicity test, $LD_{50}$ of the Keumsa (Phellinus linteus) extract showed 632.84 mg/kg (♂) and 814.48 mg/kg (♀) after intravenous administration. In addition, liver and spleen weight were increased in a dose-dependent manner. In the subacute toxicity test, the mice were intravenously administered over the course of 28 days. The $LD_{50}$ of the Keumsa (Phellinus linteus) extract showed 355.41 mg/kg (♂) and 383.53 mg/kg (♀) after intravenous administration. The liver and spleen weight also increased in a dose-dependent manner. In the case of the group that received more than 125 mg/kg of intravenous administration, exercise capacity, such as jumping ability and agility, were significantly increased. These results suggest that Keumsa (Phellinus linteus) extract can be regarded as a potent enhancer of the innate immune response, and it can be considered as a new natural product with low toxicity that may be used as a candidate for antitumor action.

• Korean Journal of Food Science and Technology
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• v.34 no.3
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• pp.505-509
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• 2002

In the course of screening program for VHR DS-PTPase (dual-specificity protein tyrosine phosphatase) from natural sources, Gastrodia elata was selected. One compound showing potent inhibitory activity was isolated by the solvent extraction and column chromatography including silica gel, ODS RP-18, Sephades LH-20, and HPLC. This compound was identified as baicalein by several NMR techniques such as $^1H-NMR$, $^{13}C-NMR$, and DEPT. Baicalein showed selective inhibitory activity against VHR DS-PTPase with $IC_{50}=2.4\;{\mu}M$, and showed cytotoxicity against several human cancer cell lines with an $GI_{50}$ of $5.26{\sim}12.93\;{\mu}g/mL$ range, including, melanoma (LOX-IMVI), lung cancer (NCI H23 and A549), colon cancer (HCT 116 and SW 620), prostate cancer (PC-3), and leukemia (MOLT 4F).

• Women's Health Nursing
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• v.9 no.1
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• pp.39-49
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• 2003

This study is an attempt to provide fundamental information on how to manage menstruation discomforts by surveying the subjective viewpoint s on menstruation from female college students. Utilizing 40 Q-samples in Seoul between May 1 and June 30, 2001, data has been collected from 30 randomized P-samples. Data analysis involves the PC QUANL Program, Q-factor analysis, and Principal Component Analysis. The result of the data analysis gives four types of categorizat ion as follows : The first is the "inconvenience-recognizing" type that includes 10 subjects out of 30. During menstruation, this type of subject usually complained of physical discomfort such as pain in the lower back and abdomen. Even though they considered menstruation to be troublesome, they did nothing about the in convenience. The second is the "positively-accepting" type that includes 7 subjects out of 30. This type of subject takes menstruation as natural and even a privilege for a woman. They think they are blessed to conceive a new life through their biological cycle. Therefore unlike other types, they rarely complained of any physical and psychological discomfort caused by menstruation. The third is the "destined course" type that includes 6 subjects out of 30. This type of subject endures the discomfort caused by menstruation with out any medication or medical treatment. They appeared to take menstruation a s fate without having any specially negative or positive attitude. The fourth is the "negatively-accepting" type that includes 7 out 30. This type of subject takes menstruation as negative, even if it is unavoidable for a woman. Menstruation, very negatively taken, felt uncomfortable and caused them to have pain in the lower back and abdomen and an oversensitive nervous system. The four types of attitude towards menstruation show their own characteristic features in dealing with menstruation. Understanding these features in detail will enhance nursing implementation which is related to menstruation. This study is intended to provide fundamental information with which nurses can deal with menstruation problems by investigating subjective viewpoints about menstruation. This study is a stepping stone on which further study on this subject can build to develop an effective and efficient way to deal with menstruation discomforts.

• Korean Journal of Heritage: History & Science
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• v.51 no.3
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• pp.54-71
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• 2018

This year marks the 40th anniversary of the first inscription of 12 UNESCO World Heritage sites in 1978. Based on an overview of the implementation of the 'Convention Concerning the Protection of the World Cultural and Natural Heritage', this article examines the current issues of the inscription of cultural heritage over the past 40 years. In particular, this paper focuses on the case study of 'Sacred Island of Okinoshima and Munakata Region' nominated by Japan, which was inscribed on the World Heritage List at the 41st World Heritage Committee in 2017. Also, it demonstrates the recent trend and investigates the issues of imbalances in the evaluation and the decisions among relevant actors in the nomination process of World Heritage. Furthermore, this article attempts to derive feasible implications and lessons, and to generate heritage discourse by examining Japan's management in 'heritage diplomacy' of the World Heritage Convention, which is rapidly changing in the course of its nearly half a century of implementation. In conclusion, the research is expected to provide Korea with strategic guidance marking the 30th anniversary of its entry into the Convention, and to steer the future direction for the inscription and conservation of cultural heritage.

• Korean Journal of Heritage: History & Science
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• v.49 no.4
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• pp.126-155
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• 2016

This article deals with some issues with respect to the Mahan pottery excavated from the tombs. Pedestal jars with cover, small round-bottom jars, cylindrical pottery etc. had appeared in the interaction with the northern region in the dimension of the southern Korean peninsula. Especially, these relics had an important role at the route connecting the midwest region, Chungcheong(忠淸) inland and Yeongnam(嶺南) region. By this stage, the iron culture was similar to each other in the southern Korean peninsula. In addition to the inland route, the coastal passage along the west coast seems to have been used. Such signs are found in cylindrical pottery and Pedestal jars with cover. It was probably a natural phenomenon that the most powerful forces of Mahan appeared at this crossroad of cultural exchange. The unique style of Mahan pottery such as double-rim pottery had been established since the third century. After the third century, Mahan pottery varied by region depending on the tomb style. The difference roughly matches with the variations of the tomb style. But at the region of Bungumyo(mounded tomb), specific pottery such double-rim pottery had been prevalent than in other regions. And a specific style had been used in a narrow range. The pottery spread to the neighboring regions in the course of interaction and were also used in ritual practices.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.29 no.4
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• pp.182-197
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• 2011

This research was carried out to investigate the history and development process of the Bansu(泮水) which appeared uniquely at the Chinese 'temple-school(廟學)', Confucian schools as the common and necessary facility through the literature reviews and field surveys. The earliest record about the Bansu was shown in "The Book of Odes(詩經)". Originally Bansu was the water system which flowed near the 'Banpalace(泮宮)', but, in the following time, Bansu has become the symbol of the school which was built by the feudal lords and a very important element in the temple-school landscape. Temple-schools were started at Song(宋) Dynasty and at that time there was no certain form of Bansu, just the natural water course near the structure. Until Ming Dynasty, the "Picture of the Feudal lords' Ban-su" in the book "Samjedohoe(三才圖會)" that compiled by Wang-Xi(王圻), the form of Bansu was appeared to be transformed as the half-round pond. And the half-round pond as called Banji(泮池) of today's form was all rebuilt after Ming Dynasty. The half-moon pond appeared at the private houses, shrines, temples and villages were influenced by the book. From this research we can get the conclusions that Banji seemed one of the sacred one and used in the space arrangement formally for the various functions. This research has found the cultures of half-moon ponds which were used uniquely in China.

• Journal of Legislation Research
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• no.54
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• pp.111-154
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• 2018

The protection of fundamental rights of people is a natural duty of a state. Since Constitutional Law declare that a state is obliged to protect the fundamental rights of people obviously, it is reasonable to postulate that a state has a duty to protect every person's right much more positively. Of course, it is true that whereas right of freedom is much more important in modern states, the social right becomes more important currently. Nevertheless, we have no choice but to put an emphasis on the importance of the right of freedom like modern states. Thus states are still bound to try to protect the right of people, specific duty of behavior for the sake of right of freedom belongs to states. In particular, due to the fact that lifts are essential to our comfortable life and the demage from the accident concerning with the lifts is fatal, the strategy for securing the safety of using the lifts is significant to some extent. And because it is true that the experience of UK that put an emphasis on the role of civil actors is meaningful to us, there seems implications for us. Accordingly, it is possible to consider the material components such as the check of safety before installation for the sake of safety enhancement, quality control for lifts parts, specification of check criterion and variation of check cycle etc. and personal ones such as specification of qualification of competent persons, guarantee of competent person's independence, variation of obligator's duty and variation of user's obligation etc. However, as the situation of UK is one thing and that of Korea is another, we don't have to adhere to the policy and the experience of UK strictly. Rather, we had better apply the policy and experience of UK to ours appropriately.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.15 no.1
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• pp.56-61
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• 2022

In this paper, we classify and present AI algorithms and natural language processing methods used in chatbots. A framework that can be used to implement a chatbot is also described. A chatbot is a system with a structure that interprets the input string by constructing the user interface in a conversational manner and selects an appropriate answer to the input string from the learned data and outputs it. However, training is required to generate an appropriate set of answers to a question and hardware with considerable computational power is required. Therefore, there is a limit to the practice of not only developing companies but also students learning AI development. Currently, chatbots are replacing the existing traditional tasks, and a practice course to understand and implement the system is required. RNN and Char-CNN are used to increase the accuracy of answering questions by learning unstructured data by applying technologies such as deep learning beyond the level of responding only to standardized data. In order to implement a chatbot, it is necessary to understand such a theory. In addition, the students presented examples of implementation of the entire system by utilizing the methods that can be used for coding education and the platform where existing developers and students can implement chatbots.

• Journal of the Korean Society of Earth Science Education
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• v.14 no.1
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• pp.21-32
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• 2021

The recognition for future global environment was studied targeting the university students who will be grown as general public composing our society in this study. The rate recognizing as the complex space of natural objects and artifacts is very low for non-science majored university students. Also, the rate recognizing global environment change from now to the future as negative. The environment recognition should be changed as that the university students can imagine the human live together with the nature in the image of future global environment. The environment education find out and practice the method that human can co-exist together to the direction of co-exist with the nature. Also, the rate internalizing future global environment as the space the human amends for non-science majored university students. This result is interpreted as shown the point of view that the global environment can be improved by the human activity, and it suggests the direction of environment education the university should supply. The environment education direction should be converted from the eduction of environment or the eduction from environment to the education for environment. The opportunity for global environment education should be provided to all university students without the discrimination on the major in the university education course. Sustainable global environment eduction is necessary for our son and daughter live on the earth continuously.

• The Journal of the Convergence on Culture Technology
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• v.8 no.5
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• pp.497-502
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• 2022

Information delivery among young generation has a distinct tendency to prefer visual to text as means of information distribution and sharing recently, and it is natural to distribute information through Youtube or one-man broadcasting on Internet. That is, young generation usually get their information through this kind of distribution procedure. Many young generation are also drastic and more aggressive for decorating themselves very uniquely. It tends to create personal characteristics freely through drastic expression and attempt of face makeup, hair styling and fashion coordination without distinction of sex. Especially, face makeup becomes an object of major concern among males nowadays, and female of course, then it is the major means to express their personality. In this study, to meet the demands of the times, we design and implement the intellectual smart mirror application that efficiently retrieves and recommends the related videos among Youtube or one-man broadcastings produced by famous professional makeup artists to implement the face makeup congruous with our face shape, hair color & style, skin tone, fashion color & style in order to create the face makeup that represent our characteristics. We also introduce the AI technique to provide optimal solution based on the learning of user's search patterns and facial features, and finally provide the detailed makeup face images to give the chance to get the makeup skill stage by stage.