• Title/Summary/Keyword: national pandemic

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Differential Signaling and Virus Production in Calu-3 Cells and Vero Cells upon SARS-CoV-2 Infection

  • Park, Byoung Kwon;Kim, Dongbum;Park, Sangkyu;Maharjan, Sony;Kim, Jinsoo;Choi, Jun-Kyu;Akauliya, Madhav;Lee, Younghee;Kwon, Hyung-Joo
    • Biomolecules & Therapeutics
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    • v.29 no.3
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    • pp.273-281
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    • 2021
  • Severe acute respiratory syndrome CoV-2 (SARS-CoV-2) is responsible for the current coronavirus disease 2019 (COVID-19) pandemic. Signaling pathways that are essential for virus production have potential as therapeutic targets against COVID-19. In this study, we investigated cellular responses in two cell lines, Vero and Calu-3, upon SARS-CoV-2 infection and evaluated the effects of pathway-specific inhibitors on virus production. SARS-CoV-2 infection induced dephosphorylation of STAT1 and STAT3, high virus production, and apoptosis in Vero cells. However, in Calu-3 cells, SARS-CoV-2 infection induced long-lasting phosphorylation of STAT1 and STAT3, low virus production, and no prominent apoptosis. Inhibitors that target STAT3 phosphorylation and dimerization reduced SARS-CoV-2 production in Calu-3 cells, but not in Vero cells. These results suggest a necessity to evaluate cellular consequences upon SARS-CoV-2 infection using various model cell lines to find out more appropriate cells recapitulating relevant responses to SARS-CoV-2 infection in vitro.

Consumption Changes during COVID-19 through the Analysis of Credit Card Usage : Focused on Jeju Province

  • YOON, Dong-Hwa;YANG, Kwon-Min;OH, Hyeon-Gon;KIM, Mincheol;CHANG, Mona
    • The Journal of Economics, Marketing and Management
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    • v.9 no.5
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    • pp.39-50
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    • 2021
  • Purpose: This study is to analyze the changes of consumption patterns to diagnose the economic impacts on consumers' market during COVID-19, and to suggest implications to overcome the new social and economic crisis of Jeju Island. Research design, data, and methodology: We collected a set of credit card transaction records issued by BC Card Company from merchants in Jeju Special Self-Governing Province for past 4 years from 2017 to 2020 from the Jeju Data Hub run by Jeju Special Self-Governing Province. The big data contains details of approved credit card transactions including the approval numbers, amount, locations and types of merchants, time and age of users, etc. The researchers summed up amount in monthly basis, transforming big data to small data to analyze the changes of consumption before and after COVID-19. Results: Sales fell sharply in transportation industries including airlines, and overall consumption by age group decreased while the decrease in consumption among the seniors was relatively small. The sales of Yeon-dong and Yongdam-dong in Jeju City also fell significantly compared to other regions. As a result of the paired t-test of all 73 samples in Jeju City, the p-value of the mean consumption of the credit card in 2019 and 2020 is significant, statistically proven that the total consumption amount in the two years is different. Conclusions: We found there are sensitive spots that can be strategically approached based on the changes in consumption patterns by industry, region, and age although most of companies and small businesses have been hit by COVID-19. It is necessary for local companies and for the government to be focusing their support on upgrading services, in order to prevent declining sales and job instability for their employees, creating strategies to retain jobs and prevent customer churn in the face of the crisis. As Jeju Province is highly dependent on the tertiary industry, including tourism, it is suggested to create various strategies to overcome the crisis of the pandemic by constantly monitoring the sales trends of local companies.

Latent Profile Analysis of Medical Students' Use of Motivational Regulation Strategies for Online Learning (온라인 학습에서 의과대학생의 동기조절 프로파일 유형에 따른 인지학습과 학습몰입 간 관계 분석)

  • Yun, Heoncheol;Kim, Seon;Chung, Eun-Kyung
    • Korean Medical Education Review
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    • v.23 no.2
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    • pp.118-127
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    • 2021
  • Due to the coronavirus disease 2019 pandemic, the new norm of online learning has been recognized as core to medical institutions for academic continuity, and students are expected to be motivated and engaged in learning while maintaining distance from other peers and educators. To facilitate students' and educators' newly defined roles in online medical education settings, it is crucial to understand how students are actively motivated and engaged in learning. Hence, this study explored medical students' motivational regulation profiles and examined the effects of motivational regulation strategies (MRS) on cognitive learning and learning engagement for online learning. Data were collected after the end of the first semester in 2020 from a sample of 334 medical students enrolled at a public university school of medicine. Latent profile analysis indicated three subgroups with different motivational regulation profiles: the low-profile, medium-profile, and high-profile groups. Regarding different MRS patterns in the high-profile group, mastery self-talk, performance approach self-talk, and the self-consequating strategy appeared to be most applicable for regulating learners' motivation. Analysis of variance showed that the profile groups with higher levels of MRS use were connected to a higher willingness to use cognitive learning strategies and a higher degree of engagement in online learning. The findings of this study emphasize the use of specific sets of MRS to support learning motivation and the need to design effective self-regulated learning environments in online medical education settings.

Home ICTs environment for distance learning contexts: A longitudinal comparison of household smart devices (원격수업 시대, 가정의 ICTs 환경 적합성: 가구 및 가구원 수별 스마트기기 보유 단기 종단적 비교)

  • Chin, Meejung;Bae, Hanjin;Kwon, Soonbum
    • Journal of Digital Convergence
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    • v.19 no.1
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    • pp.11-22
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    • 2021
  • The COVID-19 pandemic has led to distance learning in primary and secondary school. Little has been known whether home ICTs environment is appropriate for the distance learning. This paper aims to assess the current state of ICTs environment at home for the distance learning of children. Using 2012 and 2019 Korean Media Panel Survey, we investigated the number of smart devices owned by households and found differences in ownership by household characteristics. The results showed that the majority of household owned more than one smart devices per child. However, the difference in the proportion of households with less than one device per child varied depending on whether smartphone was included in smart devices. These results imply that public intervention is needed to prevent educational inequality caused by the home ICTs environment for the distance learning.

ICT-oriented Training of Future HEI Teachers: a Forecast of Educational Trends 2022-2024

  • Olena, Politova;Dariia, Pustovoichenko;Hrechanyk, Nataliia;Kateryna, Yaroshchuk;Serhii, Nenko
    • International Journal of Computer Science & Network Security
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    • v.22 no.4
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    • pp.387-393
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    • 2022
  • The article reflects short-term perspectives on the use of information and communication technologies in the training of teachers for higher education. Education is characterized by conservatism, so aspects of systematic development of the industry are relevant to this cluster of social activity. Therefore, forecasting the introduction of innovative elements of ICT training is in demand for the educational environment. Forecasting educational trends are most relevant exactly in the issues of training future teachers of higher education because these specialists are actually the first to implement the acquired professional skills in pedagogical activities. The article aims to consider the existing potential of ICT-based learning, its implementation in the coming years, and promising innovative educational elements that may become relevant for the educational space in the future. The tasks of scientific exploration are to show the optimal formats of synergy between traditional and innovative models of learning. Based on already existing experience, extrapolation of conditions of educational process organization with modeling realities of using information and communication technologies in various learning dimensions should be carried out. Educational trends for the next 3 years are a rather tentative forecast because, as demonstrated by the events associated with the COVID-19 pandemic, the socio-cultural space is very changeable. Consequently, the dynamism of the educational environment dictates the need for a value-based awareness of the information society and the practical use of technological advances. Thus, information and communication technologies are a manifestation of innovative educational strategies of today and become an important component along with traditional aspects of educational process organization. Future higher education teachers should develop a training strategy taking into account the expediency of the ICT component.

The Relationship between Learning Behavior and Academic Achievements of Pre-service Teachers in Online Learning Using LMS (LMS를 활용한 온라인 강의 환경에서 예비교사의 학습행태와 성취도의 상관관계)

  • Choi, Youngmi;Park, Namje;Kim, Chul
    • Journal of The Korean Association of Information Education
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    • v.26 no.2
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    • pp.85-95
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    • 2022
  • This paper sought to find significant learning behavioral indicators and their correlation with the academic achievements of elementary teacher candidates engaged in an online course using MS Teams during the COVID-19 pandemic. Focused on variables such as the number of visiting days to MS Teams, on-time online assignments, conversation activities, posts, and replies, MS Insights data in the LMS environment were collected in the fall term of the 2020 academic year and analyzed in Pearson correlation and multiple regression. The number of visiting days and on-time online assignments were significantly correlated with their grades, whereas the indicators including average weekly conversation activity, posts, and replies did not have a significant effect on the achievements. Furthermore, the results revealed that the subject's behavioral intention to submit on-time assignments significantly predicted learner achievements.

Confirming the Continued Representativeness of an Online/Telephone Panel Using Equivalence Testing

  • Cho, Sung Kyum;LoCascio, Sarah Prusoff;Kim, Sungjoong
    • Asian Journal for Public Opinion Research
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    • v.9 no.2
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    • pp.188-211
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    • 2021
  • Decreasing response rates to traditional survey methods, like face-to-face and telephone interviews, have led survey practitioners around the world to seek new ways of conducting surveys in recent years." The COVID-19 pandemic exacerbated this problem because it made conducting face-to-face interviews even more difficult than before. For example, it made conducting face-to-face surveys infeasible in 2020 in South Korea, and so the Korean Academic Multimode Open Survey (KAMOS) was unable to conduct a planned face-to-face survey to recruit new panel members. The entire 8,514-member panel, established via two-stage probability-based sampling from 2016 to 2019, was invited to take three online/telephone surveys in 2020. Of these panel members, 1,352 responded to at least one survey in 2020. To test to what extent the panel remained representative of the adult South Korean population, we compared the two groups of panel members: those who responded to at least one survey in 2020 and those who did not. After weighting both groups on the basis of age, sex, and geographical area, we analyzed their responses to some of the questions that were asked during multiple rounds of the face-to-face panel-recruiting interviews. Using Cohen's d for survey items that could be analyzed numerically and Cramér's V for categorical items, we were able to conclude that the respondents to the 2020 surveys were equivalent to the non-respondents in terms of both demographics and in the answers they originally gave to substantive questions on a variety of topics related to social science or public opinion research, including questions about quality of life, societal issue, and politics (Cohen's d items <0.2, 95% CI; Cramér's V items <0.1, 95% CI). This analysis may provide a model for others who wish to test the continued representativeness of their panel or who would like to use a different survey mode or change some other aspect of their methodology and test whether it is equivalent to their former methodology. Our success in building a panel that retained its representativeness may be useful to those in other countries where face-to-face surveys had previously been the norm but are becoming increasingly difficult to conduct.

An Analysis Method and Environment for Team Project-Based Learning in Non-Face-to-Face Situation for Student Evaluation (비대면 팀 프로젝트 기반 수업 평가를 위한 분석 방법 및 평가환경)

  • Lee, Jaiyun;Han, Seyoung;Choi, Changbeom
    • Journal of Engineering Education Research
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    • v.25 no.3
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    • pp.3-10
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    • 2022
  • An educator may utilize various pedagogies such as hands-on practice, practicum, and project-based learning to enhance a student's competency. Among various pedagogies, project-based learning is one of the well-known pedagogies that may provide similar on-the-job experience. In general, an educator may divide the students into small groups and assign tasks to check students' cooperation skills and achievements during project-based learning. However, an educator may experience difficulties operating project-based learning due to the COVID-19 pandemic. Most of the team activities are done in non-face-to-face meetings, and as a consequence, the educator may not find an underachieving team easily and cannot intervene appropriately. This study introduces a rigorous analysis method to evaluate team activities to analyze individual students' participation and contributions. First, this study develops evaluation rubrics by conducting questionnaires to professors and students to find an appropriate weight value for the evaluation scale. Then, this research introduces an analysis environment to evaluate students automatically. The analysis environment collects dialog data from social network services and measures interactions among students in a team. After measuring interactions, the environment generates a report to visualize the team activities. We applied the proposed method and environment to the capstone design course to show the effectiveness of the method and environment. Based on the case study, the environment showed that the analysis method could easily indicate the teams' activities and check the level of participation.

Youth Audience Development in the Non-face-to-Face Era: An Action Research of National Theater Company's (비대면 시대의 청소년 관객개발 - 국립극단 어린이청소년극 <영지> 실행연구 -)

  • Jung, Yong Sung;Chang, WoongJo
    • Korean Association of Arts Management
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    • no.56
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    • pp.217-242
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    • 2020
  • At a moment in which the entire culture and arts field is in crisis due to the Covid-19 pandemic, the audience development strategies practiced by arts organizations require significant adaptation. In this paper we consider the theater for young audiences, Youngji, produced by the TYA(Theater for Young Audiences) Research Center(TYARC) of the National Theater Company of Korea (NTCK). We examine how an arts organization develops youth audiences and creates a participatory culture when normal non-face-to-face engagement is not possible. We applied an Action Research methodology to our research filed, which allowed us to track continuous change based on the evolving practices and contingencies of one arts sector organization. Using Brown and Novak-Leonard's (2011) audience involvement spectrum, Koste's (1995) concept of creative drama, and Moore's (1993) transactional distance theory, we explored the possibility of active audience development by analyzing the ways in which NTCK's arts education has adapted its approach to audience development. We find that, even in this non-face-to-face era, it is possible to effectively develop youth audiences through a dramatic play that continues from play to drama.

A Study on IKE v2 Analysis Method for RealTime (NIKEv2 AR : IKE v2 실시간 분석 기술 연구)

  • Park, Junghyung;Ryu, Hyungyul;Ryou, Jaecheol
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.32 no.4
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    • pp.661-671
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    • 2022
  • Due to the COVID-19 pandemic, remote working, e-learning, e-teaching and online collaboration have widely spread and become popular. Accordingly, the usage of IPsec VPN for security reasons has also dramatically increased. With the spread of VPN, VPN vulunerabilities are becoming an important target of attack for attackers, and many studies have been conducted on this. IKE v2 analysis is an essential process not only for developing and building IPsec VPN systems but also for security analysis. Network packet analysis tools such as Wireshark and Tcpdump are used for IKE v2 analysis. Wireshark is one of the most famous and widely-used network protocol analyzers and supports IKE v2 analysis. However Wireshark has many limitations, such as requiring system administrator privileges for IKE v2 analysis. In this paper, we describe Wireshark's limitations in detatil and propose a new analysis method. The proposed analysis method can analyze all encrypted IKE v2 messages in real time from the session key exchange In addition, the proposed analysis method is expected to be used for dynamic testing such as fuzzing as packet manipulation.