• 제목/요약/키워드: national food

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애기외톨개모자반 (Myagropsis yendoi) 추출물의 항균활성 (Antimicrobial Activity of Myagropsis yendoi Extract)

  • 박나비;송유진;김꽃봉우리;이청조;정지연;곽지희;최문경;김민지;남기완;안동현
    • 한국수산과학회지
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    • 제43권6호
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    • pp.642-647
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    • 2010
  • This study examined the antimicrobial activity of Myagropsis yendoi (MY). The antimicrobial activity of ethanol and aqueous MY extracts were measured using a paper disc assay. The MY ethanol extract had the best antimicrobial activity. It inhibited the growth of Candida tropicalis and Gram-positive bacteria such as Bacillus subtilis, Listeria innocua, L. monocytogenes, and Staphylococcus aureus at 4 mg/mL. The minimum inhibitory concentration (MIC) of the MY ethanol extract ranged from 0.1 to 0.5%. The MY ethanol extract inhibited the growth of B. subtilis and L. innocuaat concentrations of 0.15% and 0.1%, respectively. The antimicrobial activity of the MY ethanol extract was not affected by heating at $121^{\circ}C$ for 15 min or pH 2.10. Therefore, the main substances responsible for the antimicrobial activity of the MY ethanol extract are believed to be stable with changing heat and pH.

생물학적제제의 치메로살 함량 정량을 위한 가열기화 아말감 흡광도법의 확립 및 검증 (Establishment and Validation of Gold Amalgamation Method for the Quantitation of Thimerosal in Biological Products)

  • 김병철;김도근;홍성화;김연희;임종미;원윤정;김석환;홍지영;윤영민;김재옥
    • 약학회지
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    • 제55권4호
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    • pp.284-288
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    • 2011
  • The test method for biologics of lot release system is based on 'Test procedure and specification for biological products,' generally, thimerosal content is measured by chemical analysis using O.D. In this study, the comparative analysis was carried out using the gold amalgamation method for thimerosal content was compared to the existing methods, which are described above. The gold amalgamation method, which uses atomic absorption spectrophotometry, was meets all the method validation acceptance criteria. It is considered to be proper as the assay and identification test for thimerosal. In this study, the comparative analysis was performed three times. As a result, gold amalgamation method is more convenient and easy to perform as this assay doesn't have pre-treatment procedure. Also this assay showed good precision and reproducibility compared to the conventional method. Therefore, it is appropriate to alternate the assay method of thimerosal from the conventional chemical analysis to gold amalgamation method to improve the credibility of lot release system and the quality control of biologics, by standardizing test method.

INHIBITION OF NEURITE OUTGROWTH AND TRANSCRIPTION FACTOR ACTIVATION BY OCHRATOXIN A IN CULTURED PC-12 CELLS

  • Hong, Jin-Tae;Oh, Jae-Ho;Jung, Kyoung-Mi;Lee, Eun-Hee;Park, Ki-Sook;Song, Chi-Won;Jung, Hai-Kwan;Lee, Myung-Koo;Yang, Ki-Hwa;Chung, Soo-Youn
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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    • pp.168-168
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    • 2001
  • The mycotoxin, ochratoxin A (OTA) has been known to induce microcephaly in animals and in vitro whole embryo. Cytotoxic effect and inhibition of cell differentiation were proposed as underlying mechanisms responsible for OTA-induced microcephaly.(omitted)

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Retraction: Saccharomyces cerevisiae 와 Hanseniaspora uvarum 효모 혼합발효를 이용한 증류식 소주의 휘발성 향기성분 및 아미노산 함량 변화 (Retraction: Changes in the volatile aromatic compounds and amino acid contents of distilled soju using co-fermentation by Saccharomyces cerevisiae and Hanseniaspora uvarum yeasts)

김(Pyropia yezoensis) 물 추출 천연 색소의 첨가에 의한 수리미 혼합물의 특성 변화 (Properties of a Fish Surimi Mixture for Using Pigments from Laver Pyropia yezoensis)

  • 박예린;한현수;강유석;박정철;서훈서;최예희;김수형;우가은;이가혜;안동현
    • 한국수산과학회지
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    • 제55권6호
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    • pp.802-807
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    • 2022
  • We investigated the physical properties and color values of surimi mixtures with added natural red pigments from laver Pyropia yezoensis. After adding the natural red pigment from seaweed extract to surimi, the hardness, gumminess, and chewiness of the surimi decreased compared to the negative controls. The L* color value was lower for the surimi mixture than the negative controls, but the a* and b* color values were higher. After cold storage for 7 days, the unheated surimi mixture showed increased firmness, but decreased adhesiveness. Moreover, the gumminess and chewiness of the surimi mixture stored after heating were increased compared to the pre-storage values. These results indicate that seaweed extract pigments may be used as additives for surimi, to increase the color preference, with little effect on the physical properties.

건강기능식품 부작용 원인분석을 위한 알고리즘 (Algorithms for Causality Evaluation of Adverse Events from Health/Functional Foods)

  • 이경진;박경식;김정훈;이영주;윤태형;노기미;박미선;임동길;윤창용;정자영
    • 한국식품위생안전성학회지
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    • 제26권4호
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    • pp.302-307
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    • 2011
  • One of the most important objectives of post-marketing monitoring of dietary supplements is the early detection of unknown and unexpected adverse events (AEs). Several causality algorithms, such as the Naranjo scale, the RUCAM scale, and the M & V scale are available for the estimation of the likelihood of causation between a product and an AE. Based on the existing algorithms, the Korea Food & Drug Administration has developed a new algorithm tool to reflect the characteristics of dietary supplements in the causality analysis. However, additional work will be required to confirm if the newly developed algorithm tool has reasonable sensitivity and not to generate an unacceptable number of false positives signals.