Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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INHIBITION OF NEURITE OUTGROWTH AND TRANSCRIPTION FACTOR ACTIVATION BY OCHRATOXIN A IN CULTURED PC-12 CELLS

  • Hong, Jin-Tae (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Oh, Jae-Ho (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Jung, Kyoung-Mi (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Lee, Eun-Hee (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Park, Ki-Sook (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Song, Chi-Won (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Jung, Hai-Kwan (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Lee, Myung-Koo (College of Pharmacy, Chungbuk National University) ;
  • Yang, Ki-Hwa (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
  • Chung, Soo-Youn (National Institute of Toxicological Research, Korea Food and Drug Administration)
  • Published : 2001.05.01
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Abstract

The mycotoxin, ochratoxin A (OTA) has been known to induce microcephaly in animals and in vitro whole embryo. Cytotoxic effect and inhibition of cell differentiation were proposed as underlying mechanisms responsible for OTA-induced microcephaly.(omitted)

Keywords