• Title/Summary/Keyword: nano-tech

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Two-Dimensional Arrays of Gold Nanoparticles for Plasmonic Nanosensor

  • Sim, Brandon;Monjaraz, Fernando;Lee, Yong-Joong;Park, So-Yeun
    • Korean Journal of Materials Research
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    • v.21 no.10
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    • pp.525-531
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    • 2011
  • Two dimensional (2D) arrays of noble metal nanoparticles are widely used in the sensing of nanoscale biological and chemical events. Research in this area has sparked considerable interest in many fields owing to the novel optical properties, e.g., the localized surface plasmon resonance, of these metallic nanoarrays. In this paper, we report successes in fabricating 2D arrays of gold nano-islands using nanosphere lithography. The reproducibility and the effectiveness of the nano-patterning method are tested by means of spin coating and capillary force deposition. We found that the capillary force deposition method was more effective for nanospheres with diameters greater than 600 nm, whereas the spin coating method works better for nanospheres with diameters less than 600 nm. The optimal deposition parameters for both methods were reported, showing about 80% reproducibility. In addition, we characterize gold nano-island arrays both geometrically with AFM as well as optically with UV-VIS spectrometry. The AFM images revealed that the obtained nano-arrays formed a hexagonal pattern of truncated tetrahedron nano-islands. The experimental and theoretical values of the geometric parameters were compared. The 2D gold nano-arrays showed strong LSPR in the absorption spectra. As the nano-islands increased in size, the LSPR absorption bands became red-shifted. Linear dependence of the plasmon absorption maximum on the size of the gold nano-islands was identified through the increment in the plasmon absorption maximum rate for a one nanometer increase in the characteristic length of the nano-islands. We found that the 2D gold nano-arrays showed nearly seven-fold higher sensitivity of the absorption spectrum to the size of the nano-islands as compared to colloidal gold nano-particles.

A Study of 17×17 LED Dot Matrix for offring Various Contents (다양한 콘텐츠 제공을 위한 17×17 LED 도트 매트릭스 제작 및 연구)

  • Bae, Ye-Jeong;Kwon, Jong-Man;Jeong, Sun-Ho;Park, Goo-Man;Cha, Jae-Sang
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2016.11a
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    • pp.197-198
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    • 2016
  • 최근 RGB LED 조명은 다양한 장점으로 이를 활용한 연구가 진행되고 있으며 단순 조명이 아닌 정보전달 및 공간연출의 디자인적 요소의 역할을 이행하기도 한다. RGB의 혼합으로 다양한 색상이 표현 가능한 LED를 사용하여 개별적으로 LED를 제어해 여러 가지 색상 및 모양이 표현 가능한 LED 도트 매트릭스를 제작하였으며, 이를 활용해 다양한 콘텐츠를 출력하고자 한다. 다양한 모양의 콘텐츠에선 개별적으로 LED를 제어하고, 그 외의 콘텐츠에선 원하는 LED를 그룹지어 제어한다. 본 논문에서 제작한 LED 도트 매트릭스는 많은 정보를 전달 할 수 있으며, 다양한 콘텐츠 제공으로 인한 상업화 및 효율성의 확대를 꾀할 수 있다.

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A study on the Band Gap Energy Measurement of Liquid Phase Photocatalytic Sols (액상 광촉매 졸의 밴드갭 에너지 측정 연구)

  • Yoon, Cho-Rong;Qamar, Mohamad;Oh, Hyo-Jin;Hwang, Jong-Seon;Kim, Sun-Jae
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.12a
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    • pp.39-42
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    • 2006
  • Titania sols or powders were are very promising materials for environment as photocatalyst. The band gap energy of $TiO_2$ has been known to be 2.8 to 3.2 eV. But the measuring system of its band gap is usually depend on absorption properties. Thus, in this study, absorption properties of $TiO_2$ sols prepared by hydrothermal process were researched with the effect of various particle sizes and concentrations. The mean particle size in $TiO_2$ sols increased as 15 nm to 60 nm, absorption graph measured by UV-Vis spectrometer shows to move red-shift. When dilute solution added with $2^n$ in $TiO_2$, the band gap energy increases as linear function.

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A Study on Image Distortion Correction for Gobo Lighting Optical System (고보 조명 광학계의 이미지 왜곡 보정에 관한 연구)

  • Gyu-Ha Kim;Ji-Hwan Lee;Chang-Hun Lee;Mee-Suk Jung
    • Korean Journal of Optics and Photonics
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    • v.34 no.2
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    • pp.61-65
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    • 2023
  • This paper studies a method of applying pre-distortion to the image mask of the gobo illumination optical system to correct an irradiated image and irradiate a clear image. In the case of the gobo illumination optical system, since it is generally irradiated with a tilt, distortion in the upper and lower directions occurs severely in the image. To solve this problem, the correction coordinates of the image were derived using a proportional equation, and the distortion was corrected by applying them to the image mask. As a result, it was confirmed that the distortion was reduced by 64.5% compared to the case of using the existing image mask.

Tissue Engineered Catilage Reconstruction with Alginate Sponge Containing Demineralized Bone Particles (탈미네랄골분이 첨가된 알지네이트 스펀지에서 조직공학적 연골 재건)

  • Kim, Hye Min;Park, Jin Young;Kim, Eun Young;Song, Jeong Eun;Kwon, Soon Yong;Chung, Jin Wha;Khang, Gilson
    • Polymer(Korea)
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    • v.38 no.3
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    • pp.278-285
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    • 2014
  • Demineralized bone particles (DBP) and alginate hybrid sponges were fabricated at 10, 20, 40 and 80% DBP/alginate hybrid ratios for seeding chondrocyte. Cell proliferation was measured via MTT assay. Morphological observation, histology, biological assay and RT-PCR were performed at each time point 1, 2 and 3 weeks. The cell viability was better in 20% DBP/alginate sponges than in other sponges. SEM results showed that more attached and more proliferated cells in the 20% DBP/alginate sponges with the lapse of time. Finally, histochemical assay results showed that the phenotype of chondrocyte was well maintained and both acidic mucopolysaccharide and type II collagen was well formed at 20% sponges. This study suggested that DBP/alginate sponge may serve as a potential cell delivery vehicle and a structural basis for tissue engineered articular cartilage.

Regeneration of Intervertebral Disc Using Poly(lactic-co-glycolic acid) Scaffolds Included Demineralized Bone Particle In Vivo (In vivo 상에서 탈미네랄화된 골분이 함유된 PLGA 지지체를 이용한 추간판 디스크 재생)

  • Jang, Ji Eun;Kim, Hye Yoon;Song, Jeong Eun;Lee, Dongwon;Kwon, Soon Yong;Chung, Jin Wha;Khang, Gilson
    • Polymer(Korea)
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    • v.37 no.6
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    • pp.669-676
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    • 2013
  • Demineralized bone particle (DBP) is a biomaterial used widely in the field of tissue engineering. In this study, in order to study the effect of DBP/poly(lactic-co-glycolic acid) (PLGA) scaffold on disc regeneration in vivo environment, we prepared the porous DBP/PLGA hybrid scaffold. Disc defect was induced by removing the nucleus pulposus tissue after incision the annulus fibrosus tissue in half and scaffolds were transplanted. After 1, 2 and 3 months later, the extracted discs were confirmed by collagen synthesis and glycosaminoglycan (sGAG). We conducted histology (H&E, Safranin-O, Alcian blue, Type I Collagen, Type II Collagen). From the results, it was confirmed that collagen and sGAG content were high in DBP/PLGA scaffold, and the regeneration of intervertebral disc was possible.

Inflammatory Responses to Hydroxyapatite/Poly(lactic-co-glycolic acid) Scaffolds with Variation of Compositions (하이드록시아파타이트/락타이드 글리콜라이드 공중합체 지지체 조성에 따른 염증 완화 효과)

  • Jang, Ji Eun;Kim, Hye Min;Kim, Hyeongseok;Jeon, Dae Yeon;Park, Chan Hum;Kwon, Soon Yong;Chung, Jin Wha;Khang, Gilson
    • Polymer(Korea)
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    • v.38 no.2
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    • pp.156-163
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    • 2014
  • Hydroxyapatite has osteoconductivity, biocompatibility and noninflammatory, and it has been used clinically as artificial bone. In this study, we prepared hydroxyapatite/poly(lactic-co-glycolic acid) (PLGA) scaffolds using 0, 10, 20, 40 and 60 wt% of hydroxyapatite. We analyzed compressive strength, SEM analysis and FTIR for mechanical property of 3D hydroxyapatite/PLGA scaffolds. For biocompatibility tests, cell proliferation and viability were measured via MTT assay and SEM. We analyzed RT-PCR, FACS, histology (H&E, ED-1) for anti-inflammatory effect. This study showed that hydroxyapatite hybrid scaffolds have low inflammatory reaction compared with the PLGA. This result has a potential for the application of artificial bone graft material.

Effect of PLGA Scaffold Containing Demineralized Bone Solution for Articular Cartilage Tissue Engineering: In Vitro Test (조직공학적 연골재생을 위한 In Vitro 환경에서의 탈미네랄화 골분용액을 함유한 PLGA 지지체의 효과)

  • Ahn, Woo-Young;Kim, Hye-Lin;Song, Jeong-Eun;Lee, Dong-Won;Khang, Gil-Son
    • Polymer(Korea)
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    • v.35 no.6
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    • pp.499-504
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    • 2011
  • Articular cartilage has an intrinsic difficulty in recovering damages, which requires its tissue engineering treatment. Demineralized bone particle (DBP) contains various bioactive molecules. It is widely used biomaterials in the field of tissue engineering. We developed the synthetic/natural hybrid scaffolds with poly(lactide-co-glycolide) (PLGA) and solution of DBP. The chondrocytes were seeded on the PLGA-DBP scaffolds and MTT assay, morphological observation, biological assay for collagen, sGAG, and RT-PCR were performed to analyze the effect of the DBP on cell viability and extracellular matrix secretion. In SEM observation, we observed that PLGA-DBP scaffolds had uniform porosity. As MTT assay showed scaffolds containing DB solution had higher cell viability then only PLGA scaffolds. The PLGA-DBP scaffolds had better ECM production than PLGA scaffold. It was proven by the higher specific mRNA expression in the PLGA-DBP scaffold than that in PLGA scaffold. These results indicated that PLGA-DBP scaffolds might serve as potential cell delivery vehicles and structural bases for in vitro tissue engineered articular cartilage.

Effect of Ratio of Demineralized Bone Powder with Alginate Microcapsules on Articular Cartilage Regeneration (탈미네랄 골분이 비율별로 포접된 알지네이트 미세캡슐을 이용한 조직공학적 연골재생)

  • Kim, A Ram;Kim, Hye Min;Lee, Jung Keun;Lee, Ji Hye;Song, Jeong Eun;Yoon, Kun Ho;Lee, Dongwon;Khang, Gilson
    • Polymer(Korea)
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    • v.36 no.6
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    • pp.768-775
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    • 2012
  • Alginate, obtained from the seaweeds, is a widely used biomaterial for cell transplantation, since its positive effect on viability of capsulized cells and its easier encapsulation capability of living cells. Demineralized bone powder (DBP), derived from the natural bone tissue, is widely applied for clinical trials for its low rate of reaction and antigenicity. A chondrocyte was seeded into an alginate with DBP of different contents, and a microcapsule was produced. The adhesion and proliferation of cells was observed through the MTT analysis, and the PCR was applied to estimate the content of the glycosaminoglycan (sGAG) and collagen, and confirm the specific genetic pattern of the chondrocytes. Also, the alginate microcapsule where the chondrocyte is seeded was extracted after transplantation under the skin of a nude mouse, and was immunochemically stained. The experimental result confirmed that the alginate microcapsule containing 1% of DBP not only showed the highest proliferation of cell but had a positive effect of chondrocytes by the interaction between the alginates and the growth factor in DBP. It can be expected that the microcapsule with application of the alginates and DBP might be an appropriate scaffold for tissue engineering.