Objectives: Through using of the strong research method like a Randomized Controlled Trial: RCT, we have to heighten quality of Medical Education study. I'd like to introduce "CONSORT", which stands for Consolidated Standards of Reporting Trials. Contents: Preventive Service Task Force(200l) in USA proposed Levels of evidence for enlarging evidence-based Practice: EBP. And the CONSORT was introduced, which encompasses various initiatives developed by the CONSORT Group to alleviate the problems arising from inadequate reporting of randomized controlled trials (RCTs). the CONSORT has 13 guides like these: 1. How participants were allocated to interventions 2. Scientific background and explanation of rationale 3. Eligibility criteria for participants. The settings and locations where the data were collected. 4. Precise details of the interventions intended for each group and how and when they were actually administered 5. Specific objectives and hypotheses 6. Clearly defined primary and secondary outcome measures, When applicable. any methods to enhance the quality of measurements (e.g., multiple observations, training of assessors) 7. How sample size was determined. When applicable, explanation of any interim analyses and stopping rules 8. Method used to generate the random allocation sequence, Details of any restriction [of randomization] 9. Method used to implement the random allocation sequence 10. Who generated the allocation sequence, who enrolled participants. and who assigned participants to their groups 11. Whether or not participants, those administering the interventions, and those assessing the outcomes were blinded to group assignment. If done, how the success of blinding was evaluated 12. Statistical methods used to compare groups for primary outcome(s), Methods for additional analyses, such as subgroup analyses and adjusted analyses 13. Flow of participants through each stage (a diagram is strongly recommended) Specifically, for each group report the numbers of participants randomly assigned. receiving intended treatment, completing the study protocol. and analyzed for the primary outcome. Results and Conclusion: Randomized Controlled Trial: RCT guided of CONSORT will contribute to do stronger evidence-based medical studies.
Purpose: The purpose of this study was to investigate the effect of the number of measurement points on the calculation of transverse relaxation time (T2) with a focus on muscle T2. Materials and Methods: This study assumed that muscle T2 was comprised of a single component. Two phantom types were measured, 1 each for long ("phantom") and short T2 ("polyvinyl alcohol gel"). Right calf muscle T2 measurements were conducted in 9 healthy male volunteers using multiple-spin-echo magnetic resonance imaging. For phantoms and muscle (medial gastrocnemius), 5 regions of interests were selected. All region of interest values were expressed as the mean ${\pm}$ standard deviation. The T2 effective signal-ratio characteristics were used as an index to evaluate the magnetic resonance image quality for the calculation of T2 from T2-weighted images. The T2 accuracy was evaluated to determine the T2 reproducibility and the goodness-of-fit from the probability Q. Results: For the phantom and polyvinyl alcohol gel, the standard deviation of the magnetic resonance image signal at each echo time was narrow and mono-exponential, which caused large variations in the muscle T2 decay curves. The T2 effective signal-ratio change varied with T2, with the greatest decreases apparent for a short T2. There were no significant differences in T2 reproducibility when > 3 measurement points were used. There were no significant differences in goodness-of-fit when > 6 measurement points were used. Although the measurement point evaluations were stable when > 3 measurement points were used, calculation of T2 using 4 measurement points had the highest accuracy according to the goodness-of-fit. Even if the number of measurement points was increased, there was little improvement in the probability Q. Conclusion: Four measurement points gave excellent reproducibility and goodness-of-fit when muscle T2 was considered mono-exponential.
Kim, Jung-Ho;Yi, Myeong-Jong;Cho, Chang-Soo;Suh, Jung-Hee
Geophysics and Geophysical Exploration
/
v.10
no.4
/
pp.314-321
/
2007
Recently, multi-dimensional joint inversion of geophysical data based on fundamentally different physical properties is being actively studied. Joint inversion can provide a way to obtaining much more accurate image of the subsurface structure. Through the joint inversion, furthermore, it is possible to directly estimate non-geophysical material properties from geophysical measurements. In this study, we developed a new algorithm for jointly inverting dc resistivity and seismic traveltime data based on the multiple constraints: (1) structural similarity based on cross-gradient, (2) correlation between two different material properties, and (3) a priori information on the material property distribution. Through the numerical experiments of surface dc resistivity and seismic refraction surveys, the performance of the proposed algorithm was demonstrated and the effects of different regularizations were analyzed. In particular, we showed that the hidden layer problem in the seismic refraction method due to an inter-bedded low velocity layer can be solved by the joint inversion when appropriate constraints are applied.
Kim, Eun-Kyung;Han, Won-Jeong;Choi, Jin-Woo;Battulga, Bulgan
Imaging Science in Dentistry
/
v.48
no.1
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pp.21-30
/
2018
Purpose: To calculate the effective doses of cone-beam computed tomography (CBCT) using personal computer-based Monte Carlo (PCXMC) software (Radiation and Nuclear Safety Authority, Helsinki, Finland) and to compare the calculated effective doses with those measured using thermoluminescent dosimeters (TLDs) and an anthropomorphic phantom. Materials and Methods: An Alphard VEGA CBCT scanner (Asahi Roentgen Ind. Co., Kyoto, Japan) with multiple fields of view (FOVs) was used for this study. The effective doses of the scout and main projections of CBCT using 1 large and 2 medium FOVs with a height >10 cm were calculated using PCXMC and PCXMCRotation software and then were compared with the doses obtained using TLD-100 LiF and an anthropomorphic adult human male phantom. Furthermore, it was described how to determine the reference points on the Y- and Z-axes in PCXMC, the important dose-determining factors in this software. Results: The effective doses at CBCT for 1 large ($20.0cm{\times}17.9cm$) and 2 medium FOVs ($15.4cm{\times}15.4cm$ and $10.2cm{\times}10.2cm$) calculated by the PCXMC software were 181, 300, and $158{\mu}Sv$, respectively. These values were comparable (16%-18% smaller) to those obtained through TLD measurements in each mode. Conclusion: The use of PCXMC software could be an alternative to the TLD measurement method for effective dose estimation in CBCT with large and medium FOVs.
Osteoprotegerin (OPG) plays a core role in bone reformation by antagonizing the effect of receptor activator of nuclear factor ${\kappa}$-B ligand (RANKL), and mediates vascular calcification in cardiovascular disease patients. Thus, we aimed to examine the relationship between serum OPG levels and cardiovascular factors and inflammatory markers in metabolic syndrome patients (MS). This cross-sectional study included 96 men who visited the diet clinic between May and July 2011. Patients were classified into 2 groups based on NCEP-ATP guidelines: normal and with MS (n = 50 and 46, respectively). Physical measurements, biochemical assay were measured. Serum OPG and IL-6, diponectin and hs-CRP were assessed. MS were aged $50.02{\pm}10.85$ years, and normal patients $52.07{\pm}9.56$ years, with no significant differences. Significant differences were not observed in BMI between the 2 groups. Moreover, significant differences were not observed in serum OPG, however, the serum OPG level ($4.41{\pm}1.86pmol/L$) differed significantly between an overweight MS (BMI > 25) and normal patients. OPG was correlated to age (r = 0.410, p = 0.000), HDL-cholesterol (r = 0.209, p = 0.015), and log adiponectin (r = 0.175, p = 0.042). Multiple regression analyses using the enter method showed that age (${\beta}$ = 0.412, p = 0.000) and BMI (${\beta}$ = 0.265, p = 0.000) considerably affected OPG. In conclusion, out study showed that serum OPG levels are correlated with cardiovascular risk factors, such as BMI, HDL-cholesterol and adiponectin in MS and adiponectin, suggesting that serum OPG has potential as a cardiovascular disease indicator and predictor.
Kim, Hee-Kyung;Kim, Sung-Hun;Lee, Jai-Bong;Han, Jung-Suk;Yeo, In-Sung;Ha, Seung-Ryong
The Journal of Advanced Prosthodontics
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v.8
no.1
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pp.37-42
/
2016
PURPOSE. This study investigated the effect of amount of thickness reduction on color and translucency of dental monolithic zirconia ceramics. MATERIALS AND METHODS. One-hundred sixty-five monolithic zirconia specimens ($16.3mm{\times}16.3mm{\times}2.0mm$) were divided into 5 groups (Group I to V) according to the number of A2-coloring liquid applications. Each group was then divided into 11 subgroups by reducing the thickness up to 1.0 mm in 0.1-mm increments (Subgroup 0 to 10, n=3). Colors and spectral distributions were measured according to CIELAB on a reflection spectrophotometer. All measurements were performed on five different areas of each specimen. Color difference (${\Delta}E^*{^_{ab}}$) and translucency parameter (TP) were calculated. Data were analyzed using one-way ANOVA and multiple comparison $Scheff{\acute{e}}$ test (${\alpha}=.05$). RESULTS. There were significant differences in CIE $L^*$ between Subgroup 0 and other subgroups in all groups. CIE $a^*$ increased (0.52<$R^2$<0.73), while CIE $b^*$ decreased (0.00<$R^2$<0.74) in all groups with increasing thickness reduction. Perceptible color differences (${\Delta}E^*{^_{ab}}$>3.7) were obtained between Subgroup 0 and other subgroups. TP values generally increased as the thickness reduction increased in all groups ($R^2$>0.89, P<.001). CONCLUSION. Increasing thickness reduction reduces lightness and increases a reddish, bluish appearance, and translucency of monolithic zirconia ceramics.
To effectively maintain manufacturing collaboration, the development of effective performance measurements for the collaboration is required. Most existing key performance indicators however were developed to measure the performances of internal activities or outsourcing of a company. For that reason, it is necessary to devise new key performance indicators that the partners participating in the collaboration can arrange and compromise with each other to reflect their common goals. In this paper, we propose collaborative Key Performance Indicators(cKPIs), which is used to measure the collaboration work of multiple manufacturing partners on the basis of the Supply Chain Operations Reference(SCOR) model. Also, a modified Sigmoid function is devised as a desirability function to reflect the characteristics of Service Level Agreement(SLA) between two partners. The proposed indicators and the desirability functions can be utilized to perform and maintain the successful collaboration by providing a way to the quantitative measurement.
Fixed Electromagnetic Wave Surface Velocimetry (Fixed EWSV) has been started to be used to measure flood discharge in the mountain stream, since it has various advantages such that it works well to continuously measure stream discharge even in the night time as well as very strong weather. On the contrary, the Fixed EWSV only measures single point surface velocity, thus it does not consider varying feature of the transverse velocity profile in the given stream cross-section. In addition, a conventional value of 0.85 was generally used as the ratio for converting the measured surface velocity into the depth-averaged velocity. These aspects could bring in error for accurately measuring the stream discharge. The capacity of the EWSV for capturing rapid flow velocity was also not properly validated. This study aims at conducting error analysis of using the EWSV by: 1) measuring transverse velocity at multiple points along the cross-section to assess an error driven by the single point measurement; 2) figuring out ratio between surface velocity and the depth-averaged velocity based on the concurrent ADCP measurements; 3) validating the capacity of the EWSV for capturing rapid flow velocity. As results, the velocity measured near the center by the fixed EWSV overestimated about 15% of the cross-sectional mean velocity. The converting ratio from the surface velocity to the depth-averaged velocity was 0.8 rather than 0.85 of a conventional ratio. Finally, the EWSV revealed unstable velocity output when the flow velocity was higher than 2 m/s.
A fundamental principle in clasp selection for a specific abutment is the reduction of the transmission of excessive forces to the abutment tooth. Those forces include tilting, tipping, and stress on the abutment tooth. The flexibility of a clasp was believed to directly affect the reduction of such forces. Opinions have been expressed concerning the proper type of clasp to be used to prevent stress on periodontium. In order to evaluate and compare the various designs of a clasp system, it is necessary to measure these forces. This study compared the average measurements of forces required to dislodge three kinds of circumferential clasps having different amount of undercuts : the first with a round retentive arm, the second with a half round retentive arm, the third with a wrought wire retentive arm under tensile load. Three commonly used undercuts( 0.01, 0.02, 0.03 inch) were created on nine cast crowns, premolars and molars. The test was run six times for a same clasp. The means of tensile load required to dislodge each of the different clasps were compared statistically using the ANOVA test and multiple range test (Duncan test). The results were as follows. 1. The amount of tensile load of the wrought wire clasp was significantly different from the cast round or half round clasp (p<0.05). 2. The more amount of the undercut, the more tensile load was needed to dislodge the clasps. There were significant differences among them (p<0.05). 3. The molar showed higher tensile load than the premolar, and there was significant difference (p<0.05). 4. The means of tensile load according to clasp types showed significant differences at the molar between wrought wire clasp and cast clasp (p<0.05), but did not at the premolar.
Ji, Shengyue;Chen, Wu;Zhao, Chunmei;Ding, Xiaoli;Chen, Yongqi
Proceedings of the Korean Institute of Navigation and Port Research Conference
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v.1
/
pp.179-184
/
2006
Rapid and high-precision positioning with a Global Navigation Satellite System (GNSS) is feasible only when very precise carrier-phase observations can be used. There are two kinds of mathematical models for ambiguity resolution. The first one is based on both pseudorange and carrier phase measurements, and the observation equations are of full rank. The second one is only based on carrier phase measurement, which is a rank-defect model. Though the former is more commonly used, the latter has its own advantage, that is, ambiguity resolution will be freed from the effects of pseudorange multipath. Galileo will be operational. One of the important differences between Galileo and current GPS is that Galileo will provide signals in four frequency bands. With more carrier-phase data available, frequency combinations with long equivalent wavelength can be formed, so Galileo will provide more opportunities for fast and reliable ambiguity resolution than current GPS. This paper tries to investigate phase only fast ambiguity resolution performance with four Galileo frequencies for short baseline. Cascading Ambiguity Resolution (CAR) method with selected optimal frequency combinations and LAMBDA method are used and compared. To validate the resolution, two tests are used and compared. The first one is a ratio test. The second one is lower bound success-rate test. The simulation test results show that, with LAMBDA method, whether with ratio test or lower bound success rate validation criteria, ambiguity can be fixed in several seconds, 8 seconds at most even when 1 sigma of carrier phase noise is 12 mm. While with CAR method, at least about half minute is required even when 1 sigma of carrier phase noise is 3 mm. It shows that LAMBDA method performs obviously better than CAR method.
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