• 한국정보과학회논문지:소프트웨어및응용
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• 제31권9호
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• pp.1226-1232
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• 2004

차세대 보안 시장을 이끌어갈 신기술로 생체 인증 기술이 부상하고 있으나, 기존 시스템들은 대부분 생체 특징에 따라 개별 단위의 인증 방식을 제공하고 있다. 최근에는 이러한 개별 시스템들을 통합할 수 있도록 표준화하기 위한 연구가 활발히 이루어지고 있다. 본 논문에서는 생체 인증 기술의 표준화를 위해서 BioAPI 협회에서 발표한 BioAPI 명세서를 따르면서, 필기 서명이라는 단일 생체측정에 대해 함수적, 매개변수적, 구조적 접근법의 서로 다른 세 가지 검증기를 적용한 웹기반 인증 시스템을 제안한다. 시스템은 클라이언트-서버 구조이고, 클라이언트와 서버는 각각 BioAPI 규격에 따라 크게 세 계층으로 구성된다. 제안한 웹기반 단일 생체측정의 다중 인중 시스템은 사용자의 인증 거부율이 다소 증가되더라도 별도의 여러 생체측정을 요구하지 않으면서도 인증의 신뢰도를 크게 향상시킬 수 있다. 즉 세가지 서명 검증기를 결합한 경우, 사용자의 인증 거부율(FRR)이 약 2.7배 증가하였지만 오류 승인률(FAR)은 4만분의 1로 감소하는 것으로 나타났다. 따라서 제안한 방법은 개방형 네트워크인 인터넷에서의 효과적인 신원확인 방법으로 활용될 수 있으며, 또한 다양한 생체측정을 이용하는 시스템으로 쉽게 확장될 수 있다.

• Clinical and Experimental Pediatrics
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• 제50권9호
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• pp.862-867
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• 2007

목 적 : IOS는 호흡 노력을 요하지 않으며 호흡기 저항을 측정하는 비침습적인 방법이다. IOS를 이용하여 국내 학동기 소아에서의 표준치를 알아보고자 하였다. 방 법 : 7-12세의 건강한 소아 92명을 대상으로 IOS를 시행하였다. IOS 결과 값과 키, 몸무게, 체표 면적, 신체 질량 지수 및 나이 등의 연관성에 대하여 선형 회귀 분석을 시행하였다. 결 과 : IOS 성공률은 92.4%였다. 키, 몸무게, 체표 면적, 신체 질량 지수, 나이 등 5가지 변수값과 Rrs 및 Xrs를 분석한 결과, 키가 의미 있는 예측 인자였으며, 5가지 변수 모두 적용한 경우 가장 설명력이 높았다. 각각의 주파수에 따라 회귀 곡선 공식을 구하였으며, 이는 이전 연구들의 표준 공식과 비슷하였다. 결 론 : IOS의 표준치를 구하였으며 이를 활용하여 다양한 호흡기 질환의 진단에 활용될 수 있을 것이라 여겨진다.

• Clinical and Experimental Pediatrics
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• 제54권2호
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• pp.64-68
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• 2011

Purpose: The normal values for lung resistance and lung capacity of children, as determined by impulse oscillometry (IOS), are different for children of different ethnicities. However, reference values there is no available reference value for Korean preschool children have yet to be determined. The aim of the present study was to determine the normal ranges of IOS parameters in Korean preschool children. Methods: A total of 133 healthy Korean preschool children were selected from 639 children (aged 3 to 6 years) who attended kindergarten in Seongnam, Gyeonggi province, Korea. Healthy children were defined according to the European Respiratory Society (ERS) criteria. All subjects underwent lung function tests using IOS. The relationships between IOS value (respiratory resistance (Rrs) and reactance (Xrs) at 5 and 10 Hz and resonance frequency (RF)) and age, height, and weight were analyzed by simple linear and multiple linear regression analyses. Results: The IOS success rate was 89.5%, yielding data on 119 children. Linear regression identified height as the best predictor of Rrs and Xrs. Using stepwise multiple linear regressions based on age, height, and weight, we determined regression equations and coefficients of determination ($R^2$) for boys ($Rrs_5=1.934-0.009{\times}Height$, $R^2$=12.1%; $Xrs_5=0.774+0.006{\times}Height-0.002{\times}Age$, $R^2$=20.2% and for girls $(Rrs_5=2.201-0.012{\times}Height$, $R^2$=18.2%; $Xrs_5=-0.674+0.004{\times}Height$, $R^2$=10.5%). Conclusion: This study provides reference values for IOS measurements of normal Korean preschool children. These provide a basis for the diagnosis and monitoring of preschool children with a variety of respiratory diseases.

• 지구물리와물리탐사
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• 제20권1호
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• pp.12-17
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• 2017

동아시아 지역에 대한 지각과 상부맨틀의 속도구조를 파악하기 위해서, 레일리파 분산곡선에서 측정한 군속도 값을 사용하여 SV파 토모그래피 역산을 수행하였다. 한국, 일본, 그리고 중국에 설치된 253개의 광대역 관측소에 기록된 321개의 지진자료를 사용하였다. 다중필터기법(multiple filtering technique)을 사용하여, 3 ~ 150초 사이의 주기 범위에 대하여, 5,167개의 레일리파 분산 곡선을 획득한 후, 역산을 수행하여 깊이 10 ~ 100 km에 대한 SV파 토모그래피 모델을 얻었다. 다른 지역과는 다르게 동해지역 하부의 깊이 10 km에서 고속도 이상이 관찰되며 깊이 15 ~ 20 km에서는 강한 고속도 이상이 관측되는데, 이는 맨틀물질의 존재를 나타내는 것으로 생각된다. 따라서 모호면의 깊이가 주변지역에 비해 얕다는 것으로 추정되며, 이를 바탕으로 동해지역의 지각 두께는 10 ~ 20 km 사이로 판단된다. 고속도 이상의 존재 여부로 판단할 때, 한반도 지역의 모호면은 35 km 깊이 부근에 존재하는 것으로 생각된다. 일본열도 북동쪽 지역에서 좁은 범위지만 태평양판의 섭입이 관찰된다. 강원도 연안 하부의 100 km 깊이에서 강한 저속도 이상이 보이며, 이는 울릉도와 울릉분지 형성에 영향을 끼친 용융체의 존재로 생각된다. 또한, 야마토 분지 하부의 100 km 깊이에서 강한 저속도 이상체가 관찰되며, 이는 유체탈수(dehydration) 작용으로 인해 태평양판으로부터 유체가 빠져 나온 후 상승하면서 생성된 저속도 이상체로 해석된다.

• Journal of Preventive Medicine and Public Health
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• 제39권6호
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• pp.477-484
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• 2006

Objectives : This study was conducted to examine the association between the carotid artery intima-media thickness (IMT), plaque and cardiovascular risk factors according to gender and age. Methods : The data used for this study were obtained from 1,507 subjects (691 men, 816 women), aged 20-74 years, who participated in 'Prevalence study of thyroid diseases' in two counties of Jeollanam-do Province during July and August of 2004. The body mass index (BMI) and waist hip ratio (WHR) were calculated by anthropometry The blood pressure, pulse rate, pulse pressure, total cholesterol, triglyceride, HDL cholesterol and fasting blood sugar level were also measured. Ultrasonography was used to measure the carotid artery IMT and plaque. IMT measurements were performed at 6 sites, including both common carotid arteries, and the bulb and internal carotid arteries. The definition of the 'mean IMT' was mean value obtained from these 6 sites. Results : The ${\pm}$ standard deviation IMT values were $0.65{\pm}0.14\;and\;0.60{\pm}0.13mm$ in men and women (p<0.001), respectively. The data were analyzed according to gender and the 50 year age groups. In a multiple linear regression analysis, age and hypertension were positively associated with the mean IMT in both men and women, aged<50 years. Age, total cholesterol and smoking (current) were positively associated with the mean IMT in men $(\geq50\;years)$. Age was positively associated with the mean IMT in women $(\geq50\;years)$, but the HDL cholesterol level was negatively associated. The prevalence of plaques was 44.2%(196/443) in men and 19.4%(89/459) in women, for those greater than 50 years of age. In a multiple logistic regression analysis, age (OR=1.090, 95%CI=1.053-1.129), HDL cholesterol (OR=0.964, 95%CI=0.944-0.984), total cholesterol (OR=1.009, 95%CI=1.002-1.017)and BMI (OH=0.896, 95%CI=0.818-0.983) were independently associated with plaques in men; whereas, age (OR=1.057, 95%CI=1.012-1.103), HDL cholesterol (OR=0.959, 95%CI=0.932-0.986), pulse pressure (OR=1.029, 95%CI=1.007-1.050) and triglycerides (OR=0.531, 95%CI=0.300-0.941) were independently associated with plaques in women. Conclusions: There were significant gender and aging differences in the association between the IMT, plaque and cardiovascular risk factors. Therefore, for the prevention of atherosclerosis, selective approaches should be considered with regard to gender and age factors.

• 한국지구과학회지
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• 제26권5호
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• pp.436-442
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• 2005

한반도 남동부 경상분지의 동부에 위치한 언양 지역 일대에서 양산 단층대에 대한 물리 탐사를 수행하였다. 본 연구에 사용된 물리 탐사의 종류는 중력과 전기비저항 탐사이며 한국지질자원연구원에서 수행된 항공자력탐사자료를 분석하였다. 양산 단층대 중 언양 지역을 가로지르는 2개의 측선을 따라 총 71개 측점에서 중력을 측정하였으며, 동일한 위치에서 쌍극자배열을 이용한 전기비저항 탐사를 수행하였다. 또한, 이 지역의 광역적인 지질구조를 살펴보기 위하여 항공 자력 탐사자료를 분석하였다. 탐사 결과는 예상 단층선을 따라 동서지역의 전기 비저항, 밀도 및 자력의 분포가 서로 다른 양상으로 발달하여 있음을 보여주고 있다. 탐사 지역을 가로지르는 단층의 모습은 수직으로 잘 발달되어 있으며, 단층선을 따라 파쇄대가 자리 잡고 있음을 알 수 있는데 이는 선행 연구의 결과와 일치하고 있다. 또한 중력 자료의 경우 탐사지역의 북쪽에 비해 남쪽에서 단층 반응의 크기가 커짐을 확인할 수 있다. 본 연구의 성과는 앞으로 양산단층의 특성을 연구하는 다른 연구들의 기초 자료로 사용될 수 있을 것이다.

• Asian-Australasian Journal of Animal Sciences
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• 제28권6호
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• pp.862-869
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• 2015

The current study was designed to estimate the pork quality traits using metabolites from exsanguination blood and postmortem muscle simultaneously under the Korean standard pre- and post-slaughter conditions. A total of 111 Yorkshire (pure breed and castrated male) pigs were evaluated under the Korean standard conditions. Measurements were taken of the levels of blood glucose and lactate at exsanguination, and muscle glycogen and lactate content at 45 min and 24 h postmortem. Certain pork quality traits were also evaluated. Correlation analysis and multiple regression analysis including stepwise regression were performed. Exsanguination blood glucose and lactate levels were positively correlated with each other, negatively related to postmortem muscle glycogen content and positively associated with postmortem muscle lactate content. A rapid and extended postmortem glycolysis was associated with high levels of blood glucose and lactate, with high muscle lactate content, and with low muscle glycogen content during postmortem. In addition, these were also correlated with paler meat color and reduced water holding capacity. The results of multiple regression analyses also showed that metabolites in exsanguination blood and postmortem muscle explained variations in pork quality traits. Especially, levels of blood glucose and lactate and content of muscle glycogen at early postmortem were significantly associated with an elevated early glycolytic rate. Furthermore, muscle lactate content at 24 h postmortem alone accounted for a considerable portion of the variation in pork quality traits. Based on these results, the current study confirmed that the main factor influencing pork quality traits is the ultimate lactate content in muscle via postmortem glycolysis, and that levels of blood glucose and lactate at exsanguination and contents of muscle glycogen and lactate at postmortem can explain a large portion of the variation in pork quality even under the standard slaughter conditions.

• Toxicological Research
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• 제30권1호
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• pp.7-11
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• 2014

Malondialdehyde (MDA), used as an oxidative stress marker, is commonly assayed by measuring the thiobarbituric acid reactive substances (TBARS) using HPLC, as an indicator of the MDA concentration. Since the HPLC method, though highly specific, is time-consuming and expensive, usually it is not suitable for the rapid test in large-scale environmental epidemiologic surveys. The purpose of this study is to develop a simple and rapid method for estimating TBARS levels by using a multiple regression equation that includes TBARS levels measured with a microplate reader as an independent variable. Twelve hour urine samples were obtained from 715 subjects. The concentration of TBARS was measured at three different wavelengths (fluorescence: ${\lambda}-_{ex}$ 530 nm and ${\lambda}-_{em}$ 550 nm; ${\lambda}-_{ex}$ 515 nm and ${\lambda}-_{em}$ 553 nm; and absorbance: 532 nm) using microplate reader as well as HPLC. 500 samples were used to develop a regression equation, and the remaining 215 samples were used to evaluate the validity of the regression analysis. The induced multiple regression equation is as follows: TBARS level (${\mu}M$) = -0.282 + 1.830 ${\times}$ (TBARS level measured with a microplate reader at the fluorescence wavelengths ${\lambda}-_{ex}$ 530 nm and ${\lambda}-_{em}$ 550 nm, ${\mu}M$) -0.685 ${\times}$ (TBARS level measured with a microplate reader at the fluorescence wavelengths ${\lambda}-_{ex}$ 515 nm and ${\lambda}-_{em}$ 553 nm, ${\mu}M$) + 0.035 ${\times}$ (TBARS level measured with a microplate reader at the absorbance wavelength 532 nm, ${\mu}M$). The estimated TBARS levels showed a better correlation with, and are closer to, the corresponding TBARS levels measured by HPLC compared to the values obtained by the microplate method. The TBARS estimation method reported here is simple and rapid, and that is generally in concordance with HPLC measurements. This method might be a useful tool for monitoring of urinary TBARS level in environmental epidemiologic surveys with large sample sizes.

• 한국산업보건학회지
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• 제24권3호
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• pp.310-320
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• 2014

Backgrounds: Endotoxin, which found in the outer membrane of the gram-negative bacteria cell wall, makes up almost all of the lipopolysaccharide(LPS). When people are exposed to endotoxin,it can result in diverse health effects such as an airway irritation and inflammation, fever, malaise, bronchitis, allergic asthma, toxic pneumonitis, hypersensitivity lung disease. Cases among the elderly, children or pregnant can occur more frequently than a healthy adult if they are repeatedly exposed to the existing endotoxin. Therefore, we investigated and assessed the environmental characteristics associated with the airborne endotoxin concentration level in six hospital lobbies. Method: Endotoxin from indoor air in six hospital lobbies was measured by an area sampling method and analyzed according to American Society for Testing and Materials International(ASTM international) E2144-01. Total suspended particulate(TSP), carbon dioxide($CO_2$), temperature and humidity were also measured by using direct reading measurements or airborne sampling equipment at the same time. Environmental characteristics were appropriately divided into two or three groups for a statistics analysis. One-way analysis variable(one-way ANOVA) was used to examine a difference of the endotoxin concentration, depending on the environmental characteristics. In addition, only variables with p-value(p<0.25) were eventually designed to the best model by using multiple regression analysis. Results: The correlation analysis result indicated that TSP(p=0.003) and $CO_2$(p<0.0001) levels were significantly associated with endotoxin concentration levels. In contrast, temperature(p<0.068) and humidity(p<0.365) were not associated with endotoxin concentration. Levels of endotoxin concentration were statistically different among the environmental characteristics of Service time(p=0.01), Establishment of hospital(p<0.001), Scale of hospital(p=0.01), Day average people using hospital(p=0.03), Cleaning time of lobby(p=0.05), Season(p<0.001), and Cleaning of ventilation system(p<0.001) according to ANOVA. Finally, the best model(Adjusted R-square=72%) that we designed through a multiple regression test included environmental characteristics related to Service time, Area of lobby, Season, Cleaning of ventilation system, and Temperature. Conclusions: According to this study, our result showed a normal level of endotoxin concentration in the hospital lobbies and found environmental management methods to reduce the level of endotoxin concentration to a minimum. Consequently, this study recognized to be requirement for the management of ventilation systems and an indoor temperature in order to reduce the level of endotoxin concentration in the hospital lobbies.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 1995년도 가을 학술발표회 논문집
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• pp.15.2-22
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• 1995

Evaluating stiffness of near-surface materials has been one of the critically important tasks in many civil engineering works. It is the main goal of geotechnical characterization. The so-called deflection-response method evaluates the stiffness by measuring stress-strain behavior of the materials caused by static or dynamic load. This method, however, evaluates the overall stiffness and the stiffness variation with depth cannot be obtained. Furthermore, evaluation of a large-area geotechnical site by this method can be time-consuming, expensive, and damaging to many surface points of the site. Wave-propagation method, on the other hand, measures seismic velocities at different depths and stiffness profile (stiffness change with depth) can be obtained from the measured velocity data. The stiffness profile is often expressed by shear-wave (S-wave) velocity change with depth because S-wave velocity is proportional to the shear modulus. that is a direct indicator of stiffiiess. The crosshole and downhole method measures the seismic velocity by placing sources and receivers (geophones) at different depths in a borehole. Requirement of borehole installation makes this method also time-consuming, expensive, and damaging to the sites. Spectral-Analysis-of-Surface-Waves (SASW) method places both source and receivers at the surface, and records horizontally-propagating surface waves. Based upon the theory of surfacewave dispersion, the seismic velocities at different depths are calculated by analyzing the recorded surface-wave data. This method can be nondestructive to the sites. However, because only two receivers are used, the method requires multiple measurements with different field setups and, therefore, the method often becomes time-consuming and labor-intensive. Furthermore. the inclusion of noise wavefields cannot be handled properly, and this may cause the results by this method inaccurate. When multi-channel recording method is employed during the measurement of surface-waves, there are several benefits. First, usually single measurement is enough because multiple number (twelve or more) of receivers are used. Second, noise inclusion can be detected by coherency checking on the multi-channel data and handled properly so that it does not decrease the accuracy of the result. Third, various kinds of multi-channel processing techniques can be applied to f1lter unwanted noise wavefields and also to analyze the surface-wavefields more accurately and efficiently. In this way, the accuracy of the result by the method can be significantly improved. Fourth, the entire system of source, receivers, and recording-processing device can be tied into one unit, and the unit can be pulled by a small vehicle, making the survey speed very fast. In all these senses, multi-channel recording of surface waves is best suited for a routine method for geotechnical characterization in most of civil engineering works.