• Korean Journal of Head & Neck Oncology
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• v.17 no.2
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• pp.210-215
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• 2001

Objectives: Salivary gland neoplasms are a diverse group of benign and malignant tumors with a wide range of biologic behaviors. The surgeon must understand the pathologic behavior of each tumor type to develop an appropriate treatment plan. The authors planned this study to evaluate our clinical experiences and establish a new treatment strategy. Materials and Methods: From Sep. 1997 to June 2001, 25 cases of major salivary gland tumors which were underwent surgery were evaluated retrospectively. Results: 20 cases were benign and 5 were malignant. Most(17) of benign cases were pleomorphic adenoma and they showed wide distribution in age. Also we experienced other benign such as warthin's tumor, oncocytoma. In malignant, there were 2 cases of carcinoma ex-pleomorphic adenoma, 2 cases of adenoid cystic carcinoma, and one lymphoma. In carcinoma ex-pleomorphic adenoma, one showed dismal prognosis in spite of multimodality and the other were recurrent to be salvaged. Conclusion: We concluded that salivary gland neoplasms are challenging because of their relative infrequency, inconsistent classification, and highly variable biologic behavior. We need to establish new effective strategies with the regard of factors influencing survival.

• Journal of Yeungnam Medical Science
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• v.21 no.1
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• pp.120-126
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• 2004

Sinonasal Undifferentiated Carcinoma (SNUC) is a very rare, highly aggressive malignant tumor of the nasal cavity and paranasal sinuses. SNUC tends to present with advanced-stage disease, often with intracranial invasion. It requires an aggressive multimodality therapy that includes surgical resection. A cure rate of less than 20% is generally reported in the literature, with most patients dying within 1 year of onset of the disease. Three patients diagnosed as SNUC were treated at the Yeungnam University Medical Center between the years 2000 and 2003 were analyzed retrospectively. All patients presented with the disease very advanced. The three cases were given chemotherapy or chemotherapy with radiotherapy. Two patients died of the disease, surviving only 6 and 11 months following treatment, respectively. We did a follow-up on just the one remaining case with incomplete controlled disease for 27 months. The overall prognosis of SNUC is very poor. We consider that more intensive multimodality therapies are recommended for all patients with SNUC.

• Journal of Convergence for Information Technology
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• v.11 no.3
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• pp.174-184
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• 2021

The present study intends to understand how multimodality can be implemented in a content course curriculum and how students perceive multimodal tasks. Twenty-eight students majoring in English were engaged in a digital storytelling assignment as a part of the content curriculum. Findings from the questionnaire and reflective essays that investigated students perceptions of digital storytelling showed that students felt that the assignment helped them engage in the task and felt motivated. In comparison to traditional writing tasks, students perceived digital storytelling to be more engaging and motivating, but felt that the assignment required more mental effort and caused more anxiety. By supporting students to explore technology and implement multimodal aspects in the learning process, digital storytelling can encourage engagement and autonomous learning to create meaningful works that are purposeful and enjoyable.

• Tuberculosis and Respiratory Diseases
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• v.42 no.4
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• pp.502-512
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• 1995

Background: One quarter to one third of patients with NSCLC present with primary tumors that although confined to the thorax are too extensive for surgical resection. Until resently standard treatment for these patients had been thoracic radiation, which produces tumor regression in most patients but few cures and dismal 5-year survival rate. The fact that death for most patients with stage III tumors is caused by distant metastases has promped a reevaluation of combined modality treatment approaches that include systemic chemotherapy. Therefore, we report the results observed in a study to evaluate the effect of multimodality treatment in locally advanced non-small cell lung cancer from 1/91 to 8/93 in CNUH. Method: We grouped the patients according to the treatment modalities and evaluated response rate, median survival and the effect of prognostic variables. Among 67 patients evaluated, twenty seven patients classified with group A, received cisplatin and etoposide containing combination chemotherapy alone, eighteen patients, classified with group B, received chemotherapy and radiotherapy, fifteen patients, group C, received neoadjuvant or adjuvant chemotherapy and surgery with/without radiation therapy, seven patients, group D, received only supportive care. Result: The major response rate for group A and B was 37% and 61% respectively. There was no statistically significant difference in response rate between A and B groups(p=0.97). The analysis of prognostic factors showed that differences of age, sex, pathology, blood type, smoking year, stage and ECOG performance did not related to improvement in survival. Median survival time was 8.6 months for group A, 13.4 months for group B, 19.2 months for group C, and 5.4 months for group D, respectively and there was statistically significant difference(p=0.003), suggesting that multimodality therapy was associated with signigicant improvement in survival. Subset survival analysis showed a significant therapeutic effect for earlier stage and good performance state(p=0.007, 0.009, respectively). A possible survival advantages were observed for major response groups. Conclusion: It was suggested that multimodality therapy for the management of patients who had stage III disease, has yielded good median survival and long survival for seleted patients. But, it is necessory to validate above result with further investigation in large scale and in prospective randomized trials.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2000.04b
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• pp.449-457
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• 2000

The paper describes the study of global approximate optimization utilizing soft computing techniques such as genetic algorithms (GA's), neural networks (NN's), and fuzzy inference systems(FIS). GA's provide the increasing probability of locating a global optimum over the entire design space associated with multimodality and nonlinearity. NN's can be used as a tool for function approximations, a rapid reanalysis model for subsequent use in design optimization. FIS facilitates to handle the quantitative design information under the case where the training data samples are not sufficiently provided or uncertain information is included in design modeling. Properties of soft computing techniques affect the quality of global approximate model. Evolutionary fuzzy modeling (EFM) and adaptive neuro-fuzzy inference system (ANFIS) are briefly introduced for structural optimization problem in this context. The paper presents the success of EFM depends on how optimally the fuzzy membership parameters are selected and how fuzzy rules are generated.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1998.06a
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• pp.713-718
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• 1998

The paper is part of an investigation by the authors on development of a knowledge based frame work for multimodal medical image in collaboration with the All India Institute of Medical Science, new Delhi. After presenting the key aspects of the Dempster-Shafer Evidence theory we have presented implementation of registration and fusion of T₁and T₂ weighted MR images and CT images of the brain of an Alzheimer's patient for minimising the uncertainty and increasing the reliability for dianostics and therapeutic planning.

• Proceedings of the Korean Information Science Society Conference
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• 2003.04c
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• pp.286-288
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• 2003

모멘트 기반 정합은 전처리 과정을 통하여 수행되는 정합 대상기관의 형태정보를 추출하여, 이를 기반으로 대상기관의 무게중심 및 주축을 계산하고 이들 모멘트 정보를 일치시킴으로써 서로 다른 3차원 영상에 대한 정합을 유도하는 기법이다. 표면정보 기반 영상정합은 대상기관에서 추출된 표면정보를 기반으로 변환을 추정하여 서로 다른 영상의 전형적 형태의 유사성 정도를 최대화함으로써 정합을 수행하는 방법이다. 본 연구에서는 서로 다른 모달리티 영상에 대한 정합을 위하여 모멘트 기반 정합기법과 표면정보기반정합기법을 각기 구현하고 이들 방법에 대한 성능 및 문제점을 비교 분석하였다.

• Journal of Korean Neurosurgical Society
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• v.45 no.3
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• pp.133-142
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• 2009

The advent of endovascular therapy for intracranial aneurysms and the rapid advances in that field have supplanted microsurgical treatment for many intracranial aneurysms. Applying current outcome data and other parameters, nuances of selecting the modality of treatment for intracranial aneurysms are reviewed. Patient factors, such a age, co-morbidities, vasospasm and other medical conditions, are addressed. A custom-tailored multimodality treatment paradigm for the management of ruptured and unruptured aneurysms will maximize the favorable results seen in this difficult patient population.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.101.4-101
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• 2001

Evolutionary algorithm has been receiving a remarkable attention due to the model-free and population-based parallel search attributes and much successful results are coming out. However, there are some problems in most of the evolutionary algorithms. The critical one is that it takes much time or large generations to search the global optimum in case of the objective function with multimodality. Another problem is that it usually cannot search all the local optima because it pays great attention to the search of the global optimum. In addition, if the objective function has several global optima, it may be very difficult to search all the global optima due to the global characteristics of the selection methods. To cope with these problems, at first we propose a preprocessing process, grid-filtering algorithm(GFA), and propose a new distributed evolutionary ...

• Journal of Korea Multimedia Society
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• v.23 no.4
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• pp.603-614
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• 2020

Analyzing various works of Nam June Paik who pioneered the world of video art, we can find a number of audiovisual art pieces - in a broad sense - with the characteristics of "intermedia" that are not clearly identified as one genre. Especially, his career as a musician becomes an important clue for us to discuss the unique originality found in Paik's works. Nevertheless, examples of research that specifically explore how Paik's musicality is reflected in his artistry and could be deeply understood is still rare. This article examines Paik's audiovisual art world, and reviews how his musicality is expressed through the characteristics of media and form, as well as contributed to the ultimate technical and aesthetic realizations of his pieces from the perspective of musical synesthesia. The fact that Paik expanded the concept of music through technology, and fused different media to visualize music, is an important achievement in the context of aesthetic, synesthetic music in the field of audiovisual art.