Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Sinonasal Undifferentiated Carcinoma

부비강미분화암종 3예

  • Kim, Yong-Dae (Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University) ;
  • Kwak, Dong-Suk (Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University) ;
  • Lee, Hyung-Joong (Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University) ;
  • Sin, Jae-Heun (Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University) ;
  • Bai, Chang-Hoon (Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University) ;
  • Song, Si-Yeon (Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University)
  • 김용대 (영남대학교 의과대학 이비인후-두경부외과학교실) ;
  • 곽동석 (영남대학교 의과대학 이비인후-두경부외과학교실) ;
  • 이형중 (영남대학교 의과대학 이비인후-두경부외과학교실) ;
  • 신재흔 (영남대학교 의과대학 이비인후-두경부외과학교실) ;
  • 배창훈 (영남대학교 의과대학 이비인후-두경부외과학교실) ;
  • 송시연 (영남대학교 의과대학 이비인후-두경부외과학교실)
  • Published : 2004.06.30
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Abstract

Sinonasal Undifferentiated Carcinoma (SNUC) is a very rare, highly aggressive malignant tumor of the nasal cavity and paranasal sinuses. SNUC tends to present with advanced-stage disease, often with intracranial invasion. It requires an aggressive multimodality therapy that includes surgical resection. A cure rate of less than 20% is generally reported in the literature, with most patients dying within 1 year of onset of the disease. Three patients diagnosed as SNUC were treated at the Yeungnam University Medical Center between the years 2000 and 2003 were analyzed retrospectively. All patients presented with the disease very advanced. The three cases were given chemotherapy or chemotherapy with radiotherapy. Two patients died of the disease, surviving only 6 and 11 months following treatment, respectively. We did a follow-up on just the one remaining case with incomplete controlled disease for 27 months. The overall prognosis of SNUC is very poor. We consider that more intensive multimodality therapies are recommended for all patients with SNUC.

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