• The KIPS Transactions:PartA
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• v.10A no.5
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• pp.571-578
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• 2003

The appearnace of web technology has accelerated the development of the multimedia technology, the computer communication technology and the multimedia application contents. Researches on WBI(Web-based Instruction) system have combined the technology of the digital library and LOD,. REcently WBI(Web-based Instruction) model which is based on web has been proposed in the part of the new activity model of teaching-learning. As the demand of the customized coursewares from the lwarners is increased, the needs of the efficient and automated education agents in the web-based instruction are recognized. In this paper we propose a system monitors learner's behaviors constantly, evaluates them, and calculates his accomplishment. And the system offers suitable course to learner applying this accomplishment degree to agent's schedules. Therefore, the learner achieves an active and complete learning from the repeated and suitable course semantic-based retrieval.

• Journal of Korea Game Society
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• v.15 no.5
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• pp.89-98
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• 2015

The artificial intelligence (AI) of Non-Player Companions (NPC), especially opponents, is a key element to adjust the level of games in game design. Smart opponents can make games more challenging as well as allow players for diverse experiences, even in the same game environment. Since game users interact with more than one opponent in most of today's games, collaboration control of opponent characters becomes more important than ever before. In this paper, we introduce a cooperative strategy based on the A* algorithm for enemies' AI in the Pac-Man game. A survey from 17 human testers shows that the levels with our collaborative opponents are more difficult but interesting than those with either the original Pac-Man's personalities or the non-cooperative greedy opponents.

• Journal of Haehwa Medicine
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• v.19 no.2
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• pp.145-151
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• 2011

Backgrounds: Multidisciplinary approaches including surgery, chemotherapy, and radiation therapy are currently being performed to target various cancers in Western Medicine. However, some cancers still remain difficult to battle, which has long attracted many scientists for the discovery of new agents to fight cancers. Ginseng is one of the herbs used in Oriental Medicine including Korea, China and Japan. We have further investigated ginseng for its anticancer effect. Objective: This is a comprehensive review summary of anticancer effect of ginseng and ginsenoids as a possible agent for future cancer treatment. Methods: Data were retrieved from two web sites; www.pubmed.com and www.riss.kr, and authorized texts concerning anticancer effects of ginseng. From collected data, information on anticancer effect of ginseng was thoroughly sorted, restructured, then assessed. Results: Panax Ginseng C.A. Meyer belongs to Araliaceae Panax family, a perennial prairie plant with its root known as Ginseng Radix. Ginseng induces anticancer effect through cell cycle arrest, acceleration of apoptosis, anti-angiogenesis, and suppression of metastasis. Anticancer effect of ginseng may be due to single compound or multi-compound actions. Many studies report involvement of immune mechanisms of cytokines, Natural Killer (NK) cells, macrophages and some antibodies in enhancing anticancer effect of ginseng. In near future, possibility of applying these mechanisms into clinical trials is convinced. There were some important findings on saponin in ginsenoids in reviewing for this article; First, eradication of metastatic tumors were influenced by macrophage activation. Second, suppression of malignant melanoma cell metastasis to lung were induced by macrophage and NK cell activation in spleen with red ginseng acidic polysaccharide (RGAP). Third, final metabolites of M1, M4 had exerted anticancer effect of ginseng. Conclusion: Unknown anticancer mechanisms of ginseng have been studied for many years up until now. Ginseng is comprised of multiple bio-chemical compounds that create complex pharmaceutical interactions. Therefore, for its proper usage and safe prescription, studies on different types of ginseng and patients' susceptibility to ginseng according to their constitution and stages of the disease should be further pursued. More efforts are needed to understand the anticancer mechanisms of ginseng as well.

• Journal of Soil and Groundwater Environment
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• v.15 no.2
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• pp.47-54
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• 2010

Although the demands for the dredging work have been increasing due to social and industrial reasons including national plan for restoration of four major rivers, environmental standards or management guidelines for the dredged river sediment are limited. The suggested environmental standard for the beneficial use of dredged river sediment consists of two levels, recyclable and concern, and includes eight contaminants such as metals and organic contaminants. The systematic approach to remediate dredged river sediment is also suggested. The system consists of both washing and stabilization processes with continuous multi particle separation. In the early stage, the sediments are separated into two particle sizes. The coarse-grained sediment over 0.075 mm, generally decontaminated with less trouble, follows normal washing steps and is sent for recycling. The fine-grained sediments under 0.075 mm are separated again at 0.025 mm. The particles bigger than this second separation point are treated in two ways, advanced washing for highly contaminated sediments and stabilization for less. The lab test results show that birnessite and apatite are most effective stabilizing agents among tested for Cd and Pb. The most fine residues, down-sized by continuous particle separation, are finally sent for disposal. The system is tested for metals in this study, but is expected to be effective for organic contaminants included in the environmental standard, such as PAH and PCE. The feasibility test on the field site will be followed.

• Journal of Korea Multimedia Society
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• v.6 no.6
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• pp.1111-1119
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• 2003

The research of science and engineering needs the latest information from internet resources. But it is a complex and repeated procedure to search and filter web documents from the huge Internet resources. In this paper, we propose the PREA system, which can organize the research paper databases and search World Wide Web documents that the user is interested in. It observes the usage of the local Paper databases and presented web documents and then constructs a profile intelligently. However, to make a profile, we used the modified spreading activation network(MSAN) so that the PREA can search and filter web documents by semantic meaning of user's interest in realtime. The system constructed in multi-agents manner that can cooperate together effectively. The results show the effectiveness of our system to search web documents compared with a commercial search engine.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.26 no.2
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• pp.137-145
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• 2000

Carcinogenesis is a multi-stage process that generally consists of at least three steps; initiation, promotion, and progression. If one of these carcinogenic steps were suppressed or delayed, the cancer could be prevented. Cancer chemoprevention is defined to be inhibition or reversal of the carcinogenic process by the specific chemical agents and is a novel approach to cancer management alternative to conventional chemotherapy. Chlorophylln(CHL), a water-soluble derivative of chlorophyll, containing sodium and copper, has been known to be strong antimutagen in several test systems, but its mechanism of antimutagenic action is unknown. In the present experiment, the possibility of CHL as chemopreventive drugs on 7,12-dimethylbenz[a]anthracene(DMBA)-induced hamster buccal pouch carcinogenesis was investigated by mutagenicity test, carcinogenicity test, and frequency or spectrum of H-ras mutations in the both of DMBA-induced and chlorophylln-pretreated-DMBA induced tumor by polymerase chain reaction and non-isotopic restriction fragment length polymorphism. The treatment of CHL reduced the yields and multiplicity of the 0.5% DMBA-induced tumor, 86% to 62.5% and $3.7{\pm}0.6$ to $1.4{\pm}0.3$, respectively. The occurrence of histidine revertant by $20{\mu}mole$ DMBA was inhibited 25.6 to 81.7% by 1 to $5{\mu}M$ CHL in a dose-dependent manner. The mutation rates of H-ras gene in DMBA-induced and CHL-pretreated-DMBA induced tumor were 96%, 94% of which the most mutations were in codon 12/13. These results suggest that CHL inhibits the carcinogenic action of DMBA by the formation of complex between CHL and DMBA or the inhibition of the activation of DMBA in vivo. But CHL did not affect the mutation rates or its spectrum in already formed tumor.

• Journal of KIISE:Computing Practices and Letters
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• v.6 no.2
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• pp.254-264
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• 2000

The billing techniques to support multiple services in an ATM based broadband access network have been rarely developed. In fact, the management techniques including accounting management have only focused on a single service environment such as PSTN thus far. In this paper, we present an accounting management system, called rtFAMS, designed and implemented to provide multiple Value Added Service Providers (VASPS) the charging records for the multiple services in a broadband access network. The architecture is based on OSI system management infrastructure and TMN Q3 interface to acquire accounting information from agents in the ATM cross-connecters as well as to process the billing mechanisms in the manager. This system Is designed to actively adopt the rapidly changing service environments and B-ISDN network management techniques. It also provides real-time accounting information to users using Web in addition to supplying the billing records to VASPs.

• The KIPS Transactions:PartA
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• v.13A no.5 s.102
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• pp.455-464
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• 2006

In multi-regional mobile agent computing environments, spatial replication-based approach may be used as a representative mobile agent fault-tolerance technique because it allows agent execution to make progress without blocking even in case of agent failures. However, to apply this approach to real mobile agent-based computing systems, it is essential to minimize the overhead of locating and managing mobile agents replicated on each stage. This paper presents a new mobile agent location management protocol SRLM to solve this problem. The proposed protocol allows only the primary among all the replicated workers of each stage to register with its regional server and then, significantly reduces its location updating and message delivery overheads compared with the previous protocols. Also, the protocol addresses the location management problem incurred by electing the new primary among the remaining workers at a stage in case of the primary worker's failure.

• Archives of design research
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• v.9
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• pp.801-810
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• 1994

Design Problems are often both multidimensional and highly interactive. Very rarely does any part of a designed thing serve only one purpose. The activity of designing is thus a goal-directed activity and normally a goal-directed problem-solving activity. This means, problem solving is finding a way to get from some initial situation to a desired goal. Designers are transforming agents within a society whose goals are to improve the human condition through physical metamorphosis. Many theorist have agreed that designing involves problem solving or decision making. Accordingly evaluation plays an essential role in design activity. The evaluation factors include all attributes that have levels specified by quantitative and qualitative objectives Alternatives in multi-objective decision prOblems generally possess numerous attributes by which they can be described and compared. The evaluation factors include all attributes that have levels specified by quantitative and qualitative objectives. However since qualitative factors are difficult to quantify as numeral estimates, these factors have tended to be ignored without regard for their importance to human content. We adapted the Accumulative Evaluation Model as an evaluation algorithm for IDES. Industrial Design Evaluation System (IDES) consists of 3 major modules ( 1 Design Element, 2.Matrix, 3.Evaluation). It is intended to be an aid for design evaluation. The luther thinks IDES is a new design evaluation approach which could provide effective rating of design values to make value judgements. It is an attempt to provide industrial designers with access to design evaluation. The author's aim is to produce an Object-Oriented Evaluation System which can guide the designers and decision makers under complex design projects. It uses\ulcorner an Object-Oriented Programming for this prototype, Because of managing complexity (Flexibility and Reusability) and improving productivity(Extensibility & Maintainability and Programming by User) in software development process. The author has chose the C++ because it is a hybrid, rather than pure Object-Oriented Language.

• Korean Journal of Veterinary Service
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• v.36 no.3
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• pp.171-180
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• 2013

This study was carried out to investigate the antimicrobial resistance pattern and distribution of resistance gene in 44 Enterobacteriaceae and 21 Pseudomonas (P) aeruginosa isolated from hospitalized dogs and cats in animal hospital from 2010 to 2011 in Daegu. Among Enterobacteriaceae, Escherichia (E) coli was highly resistant to ampicillin (56.7%), followed by tetracycline (53.3%), cephalothin, streptomycine, sulfamethoxazole/trimethoprim, gentamicin and norfloxacin (40.0~43.3%). The remaining isolates of Enterobacteriaceae had high resistance to ampicillin (64.3%) and streptomycin (42.9%). Whereas, P. aeruginosa was low resistant to all antimicrobials tested (less than 15%). int I 1 gene was detected in 20 (57.1%) of 35 antimicrobial resistant Enterobacteriaceae and 2 (9.5%) of 21 P. aeruginosa., but int I 2 gene was not detected in all isolates. The eight resistance genes were found either alone or combination with other gene (s): $bla_{TEM}$, aadA, strA-strB, clmA, tetA, tetB, sul I and sul II. About 78% of integron-positive isolates were resistance to more than four antimicrobial agents. The findings suggest that class I integrons are widely distributed in E. coli among Enterobacteriaceae from dogs and cats and multi-drug resistance related to the presence of class I integrons. The prudent use of antimicrobials and continuous monitoring for companion animals are required.