• 한국잠사곤충학회지
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• 제40권1호
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• pp.13-16
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• 1998

From mulberry root bark of 13 various varieties, ${\gamma}$-Aminnobutyric acid(GABA) contents were examined on HPLC analyzer. GABA contents in mulberry root bark were affected by genotypes. Average GABA content of the 13 mulberry varieties was 2.19 mg/gDW. GABA content of the varieties ranged from 1.70 to 2.62 mg/gDW. Among the three genotypes, GABA content of the Morus Lhou was higher than the other genotype. In GABA content Hongolppong was the highest with 2.62 mg/gDW on the 13 varieties of mulberry root bark.

• 대한의생명과학회지
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• 제11권3호
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• pp.383-388
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• 2005

This study reports that the effect of Mori radicis cortex, Mulberry root-bark, on the lipid peroxidation products formation in the liver, blood serum and atherosclerosis of hypercholesterolemia rabbits fed Mulberry root-bark for eight weeks. The rabbits were permitted a fixed quantity to extract of Mulberry root-bark mixed hypercholesterol fodder. The lipid peroxidation products, malondialdehyde (MDA) was significantly diminished. Total cholesterol in serum worthily decreased. Also, triglyceride and high density lipoproteins (HDLs) increased after feeding Mori radicis cortex. Besides, thicky atheromatous plaque on the wall of aorta of rabbits fed on hypercholesterol diet were markedly attenuated by Mulberry root-bark extract. These results support and substantiate the extract of Mulberry root-bark as protection against lipid peroxidation in the liver, blood serum and atherosclerosis.

• 생약학회지
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• 제12권1호
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• pp.1-4
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• 1981

The root-bark of the mulberry tree has been used as a medicine with antitussive, antiphlogistic, diuretic etc. in Korea. Among many kinds of mulberry trees, Morus Lhou has been widely cultivated in our country. In this experiment, three substances were obtained from the root-bark of Morus Lhou removed its cork layer by column chromatography of methanol extract. One of the substances was supposed as ${\alpha}$-amyrin acetate, another was alyceride, the other was confirmed as ${\beta}$-sistosterol by chemical and physical methods.

• International Journal of Industrial Entomology and Biomaterials
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• 제44권1호
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• pp.21-27
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• 2022

Different parts of the mulberry plant are described to be potential sources of polyphenolics exhibiting strong antioxidant activity. In this study, we prepared various aqueous extracts of mulberry root bark by subjecting to steam at different temperatures and time intervals (45℃, 15 h; 70℃, 15 h; 95℃, 6 h and 95℃, 15 h) followed by extracting at 80℃ for 1 h. The total polyphenolic content ranged from 66.82-101.20 mg gallic acid equivalent (GE)/g of extract whereas the flavonoids were in the range of 13.03-25.23 mg catechin equivalent (CE)/g of extract. The extracts also exhibited strong antioxidant activities (0.99-1.66 mg trolox equivalent (TE)/g of extract in DDPH assay and 10.65-16.26 mg TE/g of extract in ABTS assay). This study clearly showed an improvement in the antioxidant activity of the water extract of mulberry root bark by the steam treatment, which can be used as a tea or health-promoting materials.

• International Journal of Industrial Entomology and Biomaterials
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• 제38권1호
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• pp.6-13
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• 2019

In the present study, we investigated the antifungal activity of methanol and ethanol extracts of different parts (leaves, twigs, and root bark) of mulberry plant against Alternaria alternata and Fusarium sp. Among them, the methanol and ethanol extracts of mulberry root bark exerted the highest inhibitory activity against the mycelial growth of A. alternata ($70.6{\pm}1.6$ to $80.8{\pm}6.7%$ and $58.7{\pm}0.0$ to $80.8{\pm}6.7%$, respectively) and Fusarium sp. ($15.5{\pm}2.7$ to $39.3{\pm}3.4%$ and $26.4{\pm}2.7$ to $47.6{\pm}4.8%$, respectively). In contrast, the methanol and ethanol extracts from mulberry leaves and twigs did not suppress the mycelial growth of these fungal species. Importantly, the methanol and ethanol extracts of mulberry leaves tended to even accelerate the mycelial growth of A. alternata and Fusarium sp. Therefore, the results of this study indicate that methanol and ethanol extracts of mulberry root bark can be used as control agents against A. alternata and Fusarium sp.

• International Journal of Industrial Entomology and Biomaterials
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• 제41권2호
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• pp.36-44
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• 2020

Mulberry root bark is one of potential plant sources for antioxidant materials which can be used for the relief of oxidative stress. To explore the effects of solvent type and temperature on the structural characteristics and antioxidant activity of the root bark extracts, we prepared various extracts of mulberry root bark (Morus alba L.) using 0 - 100 % ethanol (EtOH) at RT - 100℃. EtOH concentration and temperature critically affected the extraction yields, the content of bioactive components, and antioxidant activity of the extracts. Use of high content of EtOH solvent and low temperature resulted in the low extraction yield. Meanwhile, it was revealed that the extract prepared using absolute EtOH at room temperature contained polyphenols and flavonoids with the highest contents among other extracts. Interestingly, the temperature differently affected the polyphenol and flavonoid contents according to the solvent types. In the case of 30% EtOH solvent, polyphenol and flavonoid contents increased with an increase in temperature, whereas in the case of 70 and 100 % EtOH, these contents decreased. Using the radical scavenging assay, it was confirmed that the 100% EtOH extracts had higher antioxidant activity compared to distilled water (DW) extracts regardless of temperature. Also, heating might extract more antioxidant components from the root bark. Especially, the extract prepared using 30% EtOH solvent at 100℃ showed the highest antioxidant activity. Taken together, these experimental results imply that the extraction parameters should be designed carefully considering the productivity, the extracted bioactive components, and antioxidant activity.

• 대한임상검사과학회지
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• 제37권2호
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• pp.129-137
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• 2005

This study was performed to investigate the anti-obesitic effect of mulberry root-bark on male and female Zucker FA/FA or FA/fa rats. Obesity in the rats was induced by feeding high-lipid diet contained 3% corn oil and 1% cholesterol. Experimental groups in male and female rats were assigned to normal diet group (normal control), high-lipid diet group(positive control) and 3% mulberry root-bark powder in high-lipid diet group (MRC). The mulberry treated-group showed decreases of body weight, FER (food efficiency ratio) value and lipid peroxidation in the liver and increase of high density lipoprotein cholesterol (HDL-C) value, compared with positive control groups. Our findings suggest that mulberry root-bark has a potential role in preventing or improving obesity from the following points of view, body weight, serum lipids and antioxidant enzyme activities.

• Journal of Applied Biological Chemistry
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• 제57권4호
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• pp.295-299
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• 2014

뽕나무(Morus alba L.) 뿌리껍질을 실온에서 80% MeOH 수용액으로 추출하고 이 추출물을 EtOAC 분획, n-BuOH 분획, $H_2O$ 분획으로 나누었다. EtOAc 분획에 대하여 silica gel과 ODS column chromatography를 반복 실시하여 5종의 triterpenoid를 분리, 정제하였다. NMR, IR, 및 EI/MS 등을 해석하여, ${\alpha}$-amyrin (1), ${\alpha}$-acetyl amyrin (2), lupeol (3), betulinic acid (4) 그리고 glutinol (5)로 구조동정 하였다. 화합물 중 a-amyrin (1), lupeol (3) 그리고 glutinol (5)은 상백피로부터는 이번 실험에서 처음으로 분리되었다.

• 한국잠사곤충학회지
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• 제32권2호
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• pp.79-84
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• 1990

뽕나무 묘목의 지조 및 뿌리피부의 저장물질량이 생육에 미치는 영향을 알기 위하여 묘목의 청수부 위 3cm 부분의 가지 직경을 측정하여 7.0-7.9mm, 9.0-9.9mm 및 11.0-11.9mm의 3수준으로 구분하고, 시비구와 무시비구로 나누어 폿트에 식재재배하여 경시적으로 건물중, 신초생장, 뽕잎 생산량, 엽록소 함량, 탄수화물 함량의 변화를 조사하였다. 1. 신초가 생장함에 따라 지조 및 뿌리피부의 건물중은 식재후 5주에 최저치를 보인 후 증가하였다. 건물중의 최대 감소비율은 지조피부에서 17.5-20.1%, 뿌리 피부에서 20.1-24.6%로, 뿌리 피부의 감소율이 높았으나, 식재 후 3주까지의 초기 생장기간에는 지조피부의 감소율이 높았다. 2. 저장물질에 의존하는 생장의 한계는 식재 후 6-7주로 생각된다. 무시비구의 신초장은 식재후 6-7주에 최대를 보인 후 감소하였으나 시비구에서는 계속 생장하였다. 3. 묘목의 직경이 클수록 뽕잎 건물생산량이 많았으며, 식재후 3주에는 시비유무에 관계없이 같은 묘목굵기에서는 거의 같은 경향이었으나, 3주 이후에는 시비구가 무시비구보다 높았다. 4. 뽕잎의 엽\ulcorner소함량은 묘목이 굵을수록 높았으며, 시비구가 무시비구보다 높았다. 5. 묘목굵긷와 지조 및 뿌리피부의 건물중당 탄수화물함량간에는 일정한 경향이 없었다. 전당함량은 식재후 3주까지 일시 증가한 후 5주까지 계속 감소하였다. 그 후 시비구에서는 다시 증가하였으나, 무시비구에서는 계속 감소하였다. 환원당은 시비구 및 무시비구 모두 식재후 3주까지 증가하였으나 그 후 감소하였다. 지조 및 뿌리피부의 전분함량은 시비구 및 무시비구에서 식재 후 5주까지 감소 후 증가하였다.

• 한국잠사곤충학회지
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• 제31권1호
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• pp.12-19
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• 1989

추기 된서리로 인한 자연낙엽에 관계없이 상묘를 굴취할 수 있도록 하기 위하여 1985년부터 2년간 전국 각도 9개 지역에서 9월 30일부터 11월 20일까지 10일 간격으로 6회에 걸쳐 굴취하여 묘질을 분석한 결과 다음과 같았다. 1. 묘목의 굵기는 10월 30일까지 다소의 증가를 보였다. 2. 조기굴취는 그루당 새순의 수와 길이를 떨어뜨렸으며, 10월 30일 굴취구에서 생육이 가장 양호하였다. 3. 10월 20일 이후는 자연낙엽에 관계없이 굴취하여도 활착율과 생육에 영향을 주지 않았다. 4. 굴취시기를 늦을수록 체내에 전실소와 P함량이 증가되는 반면 K는 감소하였으며 Ca는 일정하지 않았다. 5. 전실소, P, Ca 등은 뿌리껍질에서 보다 줄기껍질에 함량이 높았으며 K는 일정하지 않았다.