• Proceedings of the Korean Operations and Management Science Society Conference
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• 2000.04a
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• pp.189-192
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• 2000

생산성 향상, 재고의 최소화, 납기일의 준수, 자원의 최대활용등을 위해 그동안 많은 생산관리 기법이 제시되어 왔으며 그중 GT, MRP, JIT 기법이 가장 많이 사용되고 있다. 각각의 시스템은 모두 장단점을 가지고 있기 때문에 이들 시스템을 혼합하면 상호간의 단점을 보완할 수 있을 것이다. GT 기법은 부품의 유사성을 이용한 기존자료의 검색 및 그룹가공을 통한 생산성 향상에 유용하며, MRP 기법은 기초자료를 이용하여 생산 및 자재계획을 동시에 수립할 수 있기 때문에 계획수립에 유용하며, JIT 기법은 낭비의 제거, 재고의 제로화, 간판을 이용한 현장관리 등을 할 수 있기 때문에 실시단계에 유용하다. 본 연구에서는 GT, MRP, JIT 기법을 비교 분석하고 이를 상호 보완할 수 있는 알고리즘을 개발하여 GT, MRP, JIT 혼합 생산시스템의 모델을 제시하고자 한다.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.23 no.58
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• pp.89-100
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• 2000

There use many production management systems for increasing productivity, minimizing inventory, keeping due dates and maximizing use of resources. MRP, GT and JIT are popular among these systems. There use many production management systems for increasing productivity, minimizing inventory, keeping due dates and maximizing use of resources. MRP, GT and JIT are popular among these systems. In this study, we had designed mixed production system which integrated searching and grouping function of GT, purchasing function of JIT and based on MRP and developed related algorithms and applied systems. The developed system was based on appling renewed algorithms for existing MRP system. To test efficiency operated real-data but we have tested renewed algorithms using sample-data because of massive real-data.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2285-2289
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• 2012

Multidrug resistance (MDR) is a main cause of failure in the chemotherapeutic treatment of malignant disorders. One of the well-known genes responsible for drug resistance encodes the multidrug resistance-associated protein (MRP1). The association of MRP1 with clinical drug resistance has not systematically been investigated in Iranian pediatric leukemia patients. We therefore applied real-time RT-PCR technology to study the association between the MRP1 gene and MDR phenotype in Iranian pediatric leukemia patients. We found that overexpression of MRP1 occurred in most Iranian pediatric leukemia patients at relapse. However, no relation between MRP1 mRNA levels and other clinical characteristics, including cytogenetic subgroups and FAB subtypes, was found.

• Proceedings of the Safety Management and Science Conference
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• 2004.05a
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• pp.299-302
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• 2004

Today, several manufacture enterprises are endeavoring constantly to receive order winners of subsidiary company product. There are tendencies to occupy competitive advantage in high position in price competition and in quality etc. But, it is not easy to keep it even if price has been cheap recently. Also, it is hard to be competitive advantage element more, because production smoothing was made much even if there is in quality. To keep or improve present competitive power, the due date rate is becoming importance. Several techniques with MRP, MRP II appeared in the 1970s by method to improve the these due date rate. These techniques have some defects to due date. Therefore, in this paper, MRP wishes to receive the due date rate that is improved more by supplementing having these defect by DBR of TOC.

• Korean Management Science Review
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• v.5 no.2
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• pp.42-47
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• 1988

본 논문은 범용 시스템으로서의 MRP에 대한 대안으로서 SNS를 소개하고, 두 시스템에 대한 비교 분석을 목적으로 한다. 이를 위해서 2장에서 MRP시스템의 문제점을 분석하고 3장에서 SNS의 기본원리를 소개한 후 4장에서 두 시스템을 비교 분석하였다.

• Annals of Surgical Treatment and Research
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• v.95 no.5
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• pp.249-257
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• 2018

Purpose: Multidrug resistance-associated protein (MRP) 2 is a glutathione conjugate in the canalicular membrane of hepatocytes. Early graft damage after liver transplantation (LT) can result in alteration of MRP2 expression. The purpose of this study was to evaluate the relationship between the pattern of MRP2 alteration and graft outcome. Methods: Forty-one paraffin-embedded liver graft tissues obtained by protocol biopsy within 2 months after LT; these were stained using monoclonal antibodies of MRP2. We selected 15 live donor biopsy samples as a control, that showed homogenous canalicular staining for MRP2. The pattern of canalicular MRP2 staining of graft was classified into 3 types: homogenous (type C0), focal (type C1), and no (type C2,) staining of the canaliculi. Results: In total, 17.1% graft tissues were type C0, 36.6% were type C1, and 46.3% were type C2. The median operation time was longer in patients with type C2 (562.6 minutes) than in patients with type C0 (393.8 minutes) (P = 0.038). The rates of posttransplant complications were higher in patients with type C2 (100%) than in patients with type C0 (42.9%) and C1 (73.3%) (P < 0.001). Conclusion: MRP2 expression pattern was altered in 82.9% after LT. The pattern of MRP2 alteration was associated with longer operation time and higher rates of post-LT complications.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.43 no.4
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• pp.133-141
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• 2020

Up to date cosmetic OEM/ODM (original equipment manufacturing/original development manufacturing) industry receives attention as a future growth engine due to steady growth. However, because of limited research and development capability, many companies have employed commercial management platforms specialized for large-sized companies; thus, overall system effectiveness and efficiency is low. Especially, MRP (material requirement planning) system introduced originally in 1970s is employed to calculate the requirement of the parts. However, dynamic nature of production lead time usually results in incorrect requirements. In addition, its algorithm does not consider the capability of the production resources. Also, because the commercial MRP system calculates all subcomponent for fixed period, the more goods have subcomponent, the slower calculation is. Therefore, conventional MRP system cannot respond complicated situation in time. In this study, we will suggest a new method that can respond to complicated situations resulting from short lead time and urgent production order in Korean cosmetic market. In particular, a distributed MRP system is proposed, that consists of multi-functional and operational modules, based on the characteristic of the BOM (bill of material). The distributed MRP system divides components (i.e. products and parts) into several fields and decrease the problem size; thus, we can respond to dynamically changed data any time. Through this solution, we can order components quickly, adjust schedules and planned quantity, and manage stocks reasonably. In addition, a prototype of the distributed MRP system is presented in this paper, in which ERP (enterprise resource planning) sever data is associated with an excel spreadsheet via MSsql. System user interface is implemented by a VBA (visual basic for applications) tool. According to a case study, response rate for delivery and planning achievement rate were enhanced about 20%, and inventory turnover was also decreased. Consequently, the proposed system improves overall profit.

• Journal of the Korea Society of Computer and Information
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• v.4 no.1
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• pp.54-61
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• 1999

The MRP, OPT and JIT systems have the respective limitations to become the suitable production management systems of the future. Therefore it is highly requested to develop an integrated production management system by the hybridization of those production systems. Accordingly, this study has focused its hybrid model using MRP, JIT and OPT. There has been many efforts in comparing and analyzing the usefulness and the limitations of those production systems and applying the usefulness to the maximum which improving and supplementing the weakpoints of respective systems. In this respect, this study develop the hybrid simulation model, and this hybrid model are evaluated and compared with MRP(Push system) and JIT(Pull system) by using a simulation.

• Korean Management Science Review
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• v.5 no.2
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• pp.57-70
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• 1988

This paper examines both MRP and JIT for reducing WIP(Work In Process). The MRP/JIT system is suitable for multi-model, small-production manufacturing comparies in Korea because of the short delivery distance and low risk of accident during delivery. The objective of this paper is to manage vendors effectively by informing supply points and quantity of parts of vendors with MRP and JIT.

• Proceedings of the Safety Management and Science Conference
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• 2001.05a
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• pp.185-188
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• 2001

Many production management systems for increasing productivity, minimizing inventory, keeping due dates and maximizing use of resources have been proposed, and GT, MRP and JIT are frequently used among these systems. The three systems have merits and demerits through comparing with each other. Because each system has mutual dependence, a hybrid production system is necessary for using their merits maximally. In this study, a hybrid production system is designed by combining GT, MRP and JIT, which is suitable in the domestic production system.