• 멤브레인
• /
• 제29권4호
• /
• pp.231-236
• /
• 2019

본 연구에서는 보습오일 및 천연유화제를 포함한 하이드로젤 비드 및 고강도 하이드로젤 매트릭스로 구성된 알지네이트 기반의 하이드로젤 멤브레인을 제조하고 용출 특성을 평가하였다. 실험 결과, 하이드로젤 비드 및 고강도 하이드로젤의 조성을 조절하여 보습오일 성분의 용출 속도를 원하는 범위로 제어할 수 있음을 확인하였다. 특히 상호 침투 고분자 네트워크 구조를 가지고 있는 고강도 하이드로젤과 하이드로젤 비드를 결합함으로써 멤브레인의 물리적 안정성을 높이고 동시에 보습오일의 용출 속도를 더욱 세밀하게 제어할 수 있음을 확인하였다.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
• /
• pp.149-162
• /
• 2003

Moisturizing the skin is one of the most important functions of skincare cosmetics, because water plays a significant role in keeping the skin healthy. There are various humectants including polyol (glycerin and 1,3-butylene glycol), water-soluble polymers, and botanical extracts. It is well known that the increased amount of polyol in lotion for obtaining high moisturizing effect gives a sticky feeling to the skin. Therefore, a few humectants that can give high moisturizing effect without a sticky feeling for lotion formula is available. On the other hand, oil-based lipstick is well known to have a difficulty to contain a large amount of hydrophilic humectants, because the humectants is unable to be mixed well into oil-based lipsticks and give the lips a peculiar taste. There are newly developed humectants, polyoxyethylene/polyoxypropylene dimethyl ether (EPDME) that can solve these problems describable above. EPDME is a random copolymer of ethylene oxide and propylene oxide. EPDME gives a low sticky feeling with a high moisturizing effect when it is used in lotion. As a remarkable character, EPDME can show not only a preventing effect on rough and dry skin, but also a improving effect upon the use for 1-4 weeks. EPDME can show a synergistic effect with glycerin on preventing to rough and dry skin. Since EPDME can be dissolved in oil-based formulation and used as an ingredient of lipsticks, EPDME can give a moisturizing effect that allows lip to be healthy condition. EPDME can also give no peculiar taste even upon the use of a large amount. EPDME is a useful cosmetic ingredient that can show a good skin care effect in both water-based formula and oil-based formula. EPDME of which polarity can be controllable is expected to be used for various cosmetic applications in near future.

• 한국응용과학기술학회지
• /
• 제40권2호
• /
• pp.309-321
• /
• 2023

편백나무(Chamaecyparis obtusa)는 측백나무과에 속하며 우리나라 남쪽 지역에서 주로 잘 자생한다. 편백나무의 목재는 재질이 우수하여 가구로서의 활용이 높으며 남은 목재, 가지, 잎은 정유 추출에 사용되고 있다. 편백 정유는 항염, 향균, 탈취, 진정 효능이 탁월한 것으로 알려져 있다. 본 연구는 이러한 편백나무의 잎에서 추출한 오일이 주름 개선, 피부 장벽 및 보습능에 미치는 영향을 평가하고자 하였다. 먼저, DPPH assay와 ABTS assay를 통해 항산화 활성을 평가한 결과, 편백 오일은 두 가지 라디칼을 농도 의존적으로 유의하게 소거하였다. 그리고 주름 생성 억제 효능 평가를 위해 elastase 활성을 측정한 결과, 편백 오일은 elastase 활성을 직접적으로 억제시킴을 확인하였다. 다음으로는 real-time PCR을 통해 유전자 발현을 확인한 결과, 편백 오일은 인간섬유아세포에서 MMP-1 유전자 발현을 유의하게 감소시켰다. 또한, 편백 오일에 의해 각질형성세포에서 filaggrin과 HAS-2 유전자 발현이 유의하게 증가함을 확인하였다. 이러한 결과를 종합해보면, 편백 오일은 주름 개선과 피부 장벽 및 보습능 강화에 도움을 주어 항노화 화장품의 기능성 원료로서 활용될 수 있을 것으로 기대된다.

• International Journal of Advanced Culture Technology
• /
• 제8권1호
• /
• pp.236-242
• /
• 2020

In this paper, we present the improvement in low moisturizing ability and stability that existing skin softeners have due to the low oil content, by developing skin softener using nanoemulsion of phospholipid liposome, based on the properties of nanoemulsion in cosmetic formulation. In this study, two types of oil; dimethicone (DC 200/6cs) or medium chain triglyceride (MCT), and two kinds of lecithin; unsaturated or saturated were respectively applied to produce nanoemulsion. In the particle size analysis of nanoemulsion, the droplet size of nanoemulsion containing DC200/6cs and unsaturated lecithin was the smallest, and all nanoemulsion showed high stability in the measurement of zeta potential. Therefore, with the smallest particle size and high stability, moisture contents and trans epidermal water loss(TEWL) were measured using the skin softener of DC200/6cs and unsaturated lecithin contained nanoemulsion, and the measurement was compared with the non-oil skin softener and the skin softener with only small amount of oil. The results showed that the moisture content of the skin softener using nanoemulsion increased greatly than other two skin softeners, showing high hydration ability and water retention capacity, and TEWL decreased greatly, therefore preventing the evaporation of moisture from the skin. As a result, the oil content and stability of the skin softener was improved by utilizing nanoemulson based of phospholipid liposome, and it is expected to be used in various ways in cosmetic industry.

• 한국응용과학기술학회지
• /
• 제20권2호
• /
• pp.101-109
• /
• 2003

Provitamin $B_5$ liquid crystal ($PVB_5$-LC) was the new emulsion system to enhance moisturizing activity on the skin. In this study, it should be mentioned that PVB5-LC could be prepared with the main compound of hydrogenated lecithin (HL) in oil-in water (O/W) emulsion. The key ingredient of humectants was contained 2% of provitamin $B_5$ ($PVB_5$) into the $PVB_5$-LC. The best suitable compositions of $PVB_5$-LC were made from 4.0 wt% of HL, 4.0 wt% of cetostearyl alcohol (CSA) as emulsifier and gelling agent, 3.0 wt% of 1,3-butylene glycol (1,3-BG) and 2.0 wt% of glycerin as moisturizers, 3.0 wt% of cyclomethicone (CMC), 3.0 wt% of isononanoate (ININ), 3.0 wt% of capric/caprylic triglyceride (CCTG), 3.0 wt% of macadamia nut oil (MNO) as emollients. As the analytical result of $PVB_5$-LC, it could know that the distribution range of particle size was 0.14 to 12.37 m level (mean size 3.24 m). It was certified the multi lamellar phase around the droplet of liquid crystal when observed the droplet particles through a polarization microscope. And it clinically was tested the effectiveness of moisturizing activity (in-vivo) compared with control sample (O/W emulsion). The effectiveness of moisturizing activity of $PVB_5$-LC with Skincon-200EX after 6 hours went up 49.0% (p<0.05, n=20) whereas the effectiveness of moisturizing activity of generally O/W emulsion cream was 25.7% (p<005, n=20). Also, in case of Comeometer CM-825, the moisturizing activity of $PVB_5$-LC after 6 hours rose 36.6% (p<0.05, n=20) whereas the effectiveness of moisturizing activity of generally O/W emulsion cream was 10.8%. Therefore, it was known that the effectiveness moisturizing activity of $PVB_5$-LC with HL was remarkably superior compared with O/W emulsion cream.

• 한국콘텐츠학회논문지
• /
• 제15권1호
• /
• pp.324-330
• /
• 2015

초음파 전파 매개물은 초음파의 손실 없는 투과력을 위한 1차적인 목적 이외에 피부위에서 탐촉소자의 부드러운 이동을 위한 부가적인 목적이 있다. 본 연구는 진단용 초음파의 고분자 수화젤, 에멀전, 오일젤의 제형이 다른 초음파 전파매개물이 갖는 피부 윤활성, 피부 보습성, 건조속도 등의 초음파 매개물의 특징을 측정하여 이미 상용화 된 기성품과 비교하였다. 마찰계수는 고점도 에멀전에서 가장 높았으며 저점도 에멀전에서는 고분자 수화젤의 평균 마찰계수와 큰 차이를 보이지 않았다. 제제의 건조속도는 고분자 수화젤이 가장 높았으며 오일 함유량이 많을수록 수분증발이 나타나지 않았다. 피부수분함량에서는 저점도 에멀전이 높은 수분함량을 나타냈으며 수분함량 감소 정도가 가장 완만히 나타났다. 오일성분을 적절히 사용한 에멀전 형태의 초음파 전파매개물은 피부 보습효과, 피부 유연작용의 피부 건강측면과 피부-탐촉소자간의 피부 윤활성면에서 효과적인 제형임을 알 수 있었다.

• The Korean Journal of Physiology and Pharmacology
• /
• 제19권6호
• /
• pp.543-547
• /
• 2015

We investigated the combined moisturizing effect of liposomal serine and a cosmeceutical base selected in this study. Serine is a major amino acid consisting of natural moisturizing factors and keratin, and the hydroxyl group of serine can actively interact with water molecules. Therefore, we hypothesized that serine efficiently delivered to the stratum corneum (SC) of the skin would enhance the moisturizing capability of the skin. We prepared four different cosmeceutical bases (hydrogel, oil-in-water (O/W) essence, O/W cream, and water-in-oil (W/O) cream); their moisturizing abilities were then assessed using a $Corneometer^{(R)}$. The hydrogel was selected as the optimum base for skin moisturization based on the area under the moisture content change-time curves (AUMCC) values used as a parameter for the water hold capacity of the skin. Liposomal serine prepared by a reverse-phase evaporation method was then incorporated in the hydrogel. The liposomal serine-incorporated hydrogel (serine level=1%) showed an approximately 1.62~1.77 times greater moisturizing effect on the skin than those of hydrogel, hydrogel with serine (1%), and hydrogel with blank liposome. However, the AUMCC values were not dependent on the level of serine in liposomal serine-loaded hydrogels. Together, the delivery of serine to the SC of the skin is a promising strategy for moisturizing the skin. This study is expected to be an important step in developing highly effective moisturizing cosmeceutical products.

• 한국응용과학기술학회지
• /
• 제35권4호
• /
• pp.1243-1249
• /
• 2018

세라마이드는 일반적으로 화장품 산업에서 피부의 보습 및 피부장벽강화에 도움을 주는 성분으로 많은 연구와 개발이 활발하게 이루어지고 있다. 이번 연구에서는 일반적인 합성 세라마이드가 아닌 달맞이꽃오일에서 얻은 천연 세라마이드를 함유한 보습크림이 피부의 보습 및 경피수분손실량의 변화에 어떤 영향을 미치는지를 확인하였다. 세라마이드를 함유한 보습크림이 세라마이드들 함유하지 않은 보습크림과 비교하여 피부보습력과 경피수분손실량에서 우수한 결과 값을 나타내었음을 확인하였다.

• 한국응용과학기술학회지
• /
• 제24권2호
• /
• pp.99-108
• /
• 2007

The cosmetic and toiletries are necessary health care & household for common life. However we need antiseptic which is effecting harmlessly to the human body. There are propolis, Lavender, Lemon, essential oil in the natural antiseptic materials. This work proceeded design Natural-antiseptic system with three materials as above-mentioned. Natural-antiseptic system was accomplished with propolis (2%), Lavender essential oil (0.3%), Lemon essential oil (0.3%) safety out of Polysorbate 20 (0.5%), Polysorbate 80 (0.5%), PEG (60) hydrogenated castor oil (0.45%), ethanol (5%). The antimicrobial test was experimented on E. coli and Bacillus stearothermophilus. In this antimicrobial test, we found that the effect of antisepsis against E. coli and Bacillus stearothermophilus with propolis 0.3%, Lavender essential oil 0.045% and Lemon essential oil 0.045% was improved. Therefore could expect Natural-antiseptic system product for moisturizing skin toner for face, nourishing essence and wet tissue for clean other things.

• 펄프종이기술
• /
• 제48권2호
• /
• pp.91-98
• /
• 2016

Cellulose nanofibrils (CNF) was made from oil palm trunk (OPT) with soda-anthraquinone pulping, chlorine dioxide bleaching, carboxymethylation, followed by mechanical grinding. Size of this CNF was 16-40 nm of width confirmed by TEM. To evaluate CNF from OPT as cosmetics raw materials for moisturizing component, water holding properties was compared with hyaluronic acid and collagen. CNF from OPT had better water holding property than collagen or hyaluronic acid whether phenoxyethanol was added as antiseptic or without additive.