• Title/Summary/Keyword: modifying factors

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Task Load Analysis of KTX Operation by Using NASA-TLX Method (NASA-TLX 방법에 의한 KTX 운전 직무부하 분석)

  • Jung, Won-Dea;Ko, Jong-Hyun;Park, Jin-Kyun;Kwak, Sang-Log;Lim, Seoung-Su
    • Proceedings of the KSR Conference
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    • 2006.11b
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    • pp.1082-1087
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    • 2006
  • Human factors still plays a significant role in railway accidents. The accidents often resulted from multiple causes of hardware failures and human errors. So to ensure the safety of railway operations, human error should be effectively prevented and managed. Among several factors influencing human performance, task load (or task complexity) is well known as a major contributor to human error. In order to reduce the potential of human error, a systematic analysis should be undertaken to evaluate task load and to reduce it by modifying task process and/or education&training. In this paper, we proposed a systematic framework for railway industry to perform task analysis and to evaluate task load, and applied it to KTX operational tasks. According to the application study, we identified 14 generic task types of KTX operation. And also this paper shows the quantitative task load of those generic tasks which were analyzed by NASA-TLX method.

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Post-Translational Modifications in Transcription Factors that Determine T Helper Cell Differentiation

  • Kim, Hyo Kyeong;Jeong, Mi Gyeong;Hwang, Eun Sook
    • Molecules and Cells
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    • v.44 no.5
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    • pp.318-327
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    • 2021
  • CD4+ T helper (Th) cells play a crucial role in the modulation of innate and adaptive immune responses through the differentiation of Th precursor cells into several subsets, including Th1, Th2, Th17, and regulatory T (Treg) cells. Effector Th and Treg cells are distinguished by the production of signature cytokines and are important for eliminating intracellular and extracellular pathogens and maintaining immune homeostasis. Stimulation of naive Th cells by T cell receptor and specific cytokines activates master transcription factors and induces lineage specification during the differentiation of Th cells. The master transcription factors directly activate the transcription of signature cytokine genes and also undergo post-translational modifications to fine-tune cytokine production and maintain immune balance through cross-regulation with each other. This review highlights the post-translational modifications of master transcription factors that control the differentiation of effector Th and Treg cells and provides additional insights on the immune regulation mediated by protein argininemodifying enzymes in effector Th cells.

The Determinants of a Health Promoting Lifestyle in High school students (고등학생의 건강증진 생활양식과 관련 요인)

  • Hong, Woi-Hyun;Kim, Chung-Nam
    • Research in Community and Public Health Nursing
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    • v.10 no.2
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    • pp.330-346
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    • 1999
  • This descriptive correlational study was conducted to identify the variables related to a health promoting lifestyle in high school students. 304 high school students and 189 vocational high school students living in Taegu city were selected by a convenience sampling method. The data were collected by self-reported questionnaires from August 24 to September 4, 1998. Pender and others' Health Promoting Lifestyle Profile, Shere et al's. Self-Efficacy scale, Wallston et al.'s Internal Health Locus of Control scale, Wares' Health self rating scale and Cohen & Hoberman's Social support scale were used. The data were analyzed by using descriptive statistics, Pearson correlation coefficient, t-test, MANOVA, ANOVA. Tukey verification and Stepwise multiple regression with an SAS program. The results of this study were as follows: 1. The average score of a health promoting lifestyle performance was 2.38(SD=.36) of a 4 point scale .Self-actualization (mean = 2.80. SD = .60). interpersonal support(mean = 2.73, SD=.47), health responsibility (mean=1.53, SD=.47), nutrition(mean=2.64, SD=.63), exercise(mean=2.71. SD=.72) and stress management(mean=2.37, SD=.58) were also analyzed. 2. The combination of self-efficacy, social-support, internal health locus of control. father's educational level and perceived health status explained 37.97% of the variance in health promoting lifestyles. 3. A Health promoting lifestyle showed significant positive correlations with self efficacy(r=.5173. p=.0011), perceived health status(r=.254, p=.001) and internal health locus of control(r=.321. p=.001). 4. According to sex(t=7.38. p=.006). economic state(F=6.62, p=.00l), Father's educational level(F=4.25, p=.005), mother's educational level(F=6.94. p=.000l), the grade of educational performance(F=3.74, p=.024), sleeping hours(F=3.47. p=.032) and social support(F=40.76, p=.0001). there were significant differences and modifying factors in health promoting lifestyles. On the basis of the above findings. self-efficacy in cognitive factors, and social support in modifying factors were identified as the variables which explained most of Pender's health-promotion model. Nursing strategies enhancing self-efficacy and social support which have a more significant effect on health promoting lifestyles should be developed. Further research is required to find out the factors influencing health pormoting lifestyle of high school students.

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Genetic Polymorphisms and Cancer Susceptibility of Breast Cancer in Korean Women

  • Kang, Dae-Hee
    • BMB Reports
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    • v.36 no.1
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    • pp.28-34
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    • 2003
  • Breast cancer is the most prevalent cancer among women in Western countries, and its prevalence is also increasing in Asia. The major risk factor for breast cancer can be traced to reproductive events that influence the lifetime levels of hormones. However, a large percentage of breast cancer cases cannot, be explained by these risk factors. The identification of susceptibility factors that predispose individuals to breast cancer (for instance, if they are exposed to particular environmental agents) could possibly give further insight into the etiology of this malignancy and provide targets for the future development of therapeutics. The most interesting candidate genes include those that mediate a range of functions. These include carcinogen metabolism, DNA repair, steroid hormone metabolism, signal transduction, and cell cycle control. We conducted a hospital-based case-control study in South Korea to evaluate the potential modifying role of the genetic polymorphisms of selected low penetrance genes that are involved in carcinogen metabolisms (i.e., CYP1A1, CYP2E1, GSTM1/T1/P1, NAT1/2, etc.), estrogen synthesis and metabolism (i.e., CYP19, CYP17, CYP1B1, COMT, ER-$\alpha$, etc.), DNA repair (i.e., XRCC1/3, ERCC2/4, ATM, AGT, etc.), and signal transduction as well as others (i.e., TGF-$\beta$, IGF-1, TNF-$\beta$, IL-1B, IL-1RN, etc.). We also took into account the potential interaction between these and the known risk factors of breast cancer. The results of selected genes will be presented in this mini-review.

Factors Related to the Output of Health Centers (보건소의 사업성과에 관련된 요인)

  • 차병준;박재용
    • Health Policy and Management
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    • v.6 no.1
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    • pp.29-58
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    • 1996
  • This study was conducted to identify the factors that affect the output of health conters. An analystical model employed in this study was developed by modifying 'input-output model' and 'organizational behavior model'. Data were collected form two source; the 1995 report of thealth center which was submitted to the Ministry of Health and Welfare and a mail survey questionary of officers at health center, including 66 directors and 1,768 staffs of the health centers in southern region. The major findings are as follows: That analysis has identified the factors associated with dependent variables: medical services provided by the health center and health program performance(HPP). The number of primary medical facilities was negatively associated with health center performance while the number of staffs, job satisfaction, and professional background of health center directors were positively associated. These independent variables accounted for 40.1% of the variance of dependent variables. The variance of HPP was significantly explained by the number of health subcenter and primary health post, priority level of public health program by hief executive officers(CEOs) and legislator. A significant relationship was found between leadership types of health center directors and the performance of maternal and child health program. Considering these results, the authors suggested that the role in medical care service of health center in the should be rearranged at local level because medical care service of the health center is competing with primary medical facilities in the same region. It is also suggested that educational efforts be made to improve leadership of the health center directors and concern with public health program by the CEOs and legislators of local governments.

A Procedure for Computing Conduction Time Series Factors for Walls and Roofs with Large Thermal Capacity by Finite Difference Method (열용량이 큰 벽체나 지붕재의 전도시계열 계수를 유한차분법으로 구하는 과정)

  • Byun, Ki-Hong
    • Journal of the Korean Solar Energy Society
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    • v.38 no.5
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    • pp.27-36
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    • 2018
  • The purpose of this paper is to apply the numerical solution procedure to compute conduction time series factors (CTSF) for construction materials with large thermal capacities. After modifying the procedure in Ref. [9], it is applied to find the CTSF for the wall type 19 and the roof type 18 of ASHRAE. The response periods for one hr pulse load are longer than 24hrs for these wall and roof. The CTSF generated using modified procedure agree well with the values presented in the ASHRAE handbook. The modified procedure is a general procedure that can be applied to find CTSF for materials with complex structures. For the large thermal capacity materials, it should be checked whether thermal response period of the material is over 24hr or not. With suggested solution procedure, it is easy to check the validity of the CTSF based on 24hr period.

Analysis of the Characteristics of an Attendee in an Elderly Nutrition Education Program -Using the Factors of Health Promotion Model- (노인영양교육프로그램 참여자의 특성 분석-건강증진모델의 요인을 중심으로-)

  • 임경숙
    • Korean Journal of Community Nutrition
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    • v.3 no.4
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    • pp.609-621
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    • 1998
  • Although many people initially enroll in health education programs, there are many instances of erratic participation and dropouts. Inconsistent participation in intervention programs minimizes their impact on health promotion. Therefore, a theoretical understanding of factors influencing participation in these programs can potentially enhance the effectiveness of its educational strategy. This study used the Pender's Health Promotion Model to examine specific factors influencing incentives to participate in an elderly nutrition education program. The Elderly Nutrition Counseling and Education Program was conducted with 147 volunteers (76 males, 71 females), aged 60 to 87, at 5 separate community elderly centers, by public health dietitians from February to April 1997. Some participants dropped out during the program. Overall, 61 people(18 males, 43 females) finished all 7 steps over 2 months. Pre-intervention data were collected by trained dietitians. This data included individual cognitive-perceptual factors(perceived benefits of nutrition improvement, importance of health, perceived control over health by multidimensional health locus of control, self esteem, perceived health status, concern about health, depression scale and social health scale), which were known to influence the likelihood of health behavior, and modifying factors(socioeconomic variables, biological characteristics, behavioral factors, such as smoking, alcohol drinking and exercise). Male finalists had a significantly lower chance for health locus of control, and better social health status with their children and grandchildren, compared to males who dropped out. Female finalists had a significantly higher locus of control regarding food behavior, higher self-esteem, better recognized nutritional status, worse self-recognized health status and lower concern about health than those who dropped out. There was no significant difference between the attendees and dropouts in age, BMI$(kg/m^2)$, Nutritional Risk Index, depression scale and daily nutrient intake. These results suggest that elderly nutrition intervention plans should focus on the individual cognitive and perceptual factors, with interpersonal influences, to increase participation in nutrition in nutrition improvement programs.

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Characteristics of Employment and Factors Affecting the Employment of Individuals with Brain Disorder (뇌병변장애인 고용특성 및 취업 영향요인)

  • Park, Ju-Young
    • The Journal of the Korea Contents Association
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    • v.19 no.5
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    • pp.542-552
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    • 2019
  • This study aimed to analyze characteristics of employment and factors affecting of employment of person with Brain disorder. Participants were 317 individuals with brain disorders. Data were analyzed using Chi-square test, regression analyses. according to the Panel Survey of Employment for the Disabled in Korea. These factors were classified into disability and health factors, employment related factors, and household related factors. First, The employment group showed significantly severe disorder, higher health status, absent of daily life helper, absent of assistive devices, higher level education, licenses, public employment service, job arrangement of acquaintance, find a job oneself, married, absent of basic living security assistance, greater supports of family compared to the unemployed group. Second, Factors affecting employment of individuals with brain disorders included daily life helper, education level, job arrangement of acquaintance, married, basic living security assistance. Base on these results, developing dailylife and education system and social supported system and modifying the benefit system can promote employment acquisition of individuals with brain disorder.

Fast Food Consumption and Related Factors among University Students in Daejeon (대전 일부지역 대학생의 패스트푸드 이용 및 이와 관련된 요인)

  • Kim, Kyung-Won;Ahn, Yun;Kim, Hyung-Mee
    • Korean Journal of Community Nutrition
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    • v.9 no.1
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    • pp.47-57
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    • 2004
  • The study purpose was to investigate the factors related to fast food consumption of university students. Factors were identified using the Theory of Planned Behavior. Based on the pilot study, 18 behavioral beliefs, 7 normative beliefs and 19 control beliefs were identified. Data (n = 269) were analyzed using analysis of variance or $X^2$,/TEX> tests. Subjects were categorized into non-users (27.9%), users (42%) and frequent users ( $\geq$ 2 times/week, 30.1%). Regarding behavioral beliefs, users or frequent users responded more positively on advantages of eating fast foods including ‘taste’ (p < 0.001), ‘making me feel full’(p < 0.001), ‘diverse menus’(p < 0.05) than non-users. Compared to users, non-users responded more positively on the item that eating fast foods leads to eat vegetables less (p < 0.05), and negatively on ‘making me eat more salt’(p < 0.05). Most of the referent groups, parents (p < 0.001), sisters/brothers (p < 0.01), relatives (p < 0.01), friends (p < 0.05), boy/girl friends (p < 0.05) were important sources of influence regarding subjects' fast food consumption. Users or frequent users felt less control over factors or situations that make it consume fast foods (9 out of 19 control beliefs). These factors included; availability issues (p < 0.001), ‘not having other foods on hand’(p < 0.01), ‘others eating together like fast foods’, ‘convenience’, ‘social increase in fast food use’, ‘easy to get fast foods anytime’(p < 0.05). In addition, users of fast foods were more likely to eat fast foods when they don't have time, when they do not like to cook, when they feel hungry (p < 0.05). These results suggest that interventions for university students include strategies to moderate fast food use by modifying behavioral beliefs, suggesting alternative menus and behavior modification techniques, increasing perception of control, and eliciting social support.

Factors Influencing the Health Examination in Unmarried Women (고연령 미혼여성의 건강검진에 영향을 미치는 요인)

  • Ha, Ju Young;Youn, Ji Hyang;Lee, Yeong Suk;Lee, Hyun Jung
    • Women's Health Nursing
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    • v.20 no.1
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    • pp.92-104
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    • 2014
  • Purpose: This study was to investigate factors that influence health examination for unmarried women. Methods: A correlation study was carried out with 144 unmarried women with an age range of 35~49 years through selfadministered questionnaires. This questionnaire included Health Belief Model modifying factors (demographic.sociological, structural, and cues to action variables). Data were analyzed using descriptive statistics, $x^2$-test, multiple logistic regression. Results: The mean age of participants was $37.2{\pm}2.67$ years. Rates for breast cancer, cervical cancer and comprehensive health examination were each 34.7%, 38.2% and 94%. In multiple logistic regression analysis, influencing factors on physical examination were age(OR=0.06, 95% CI: 0.02~0.26), personal medical insurance (OR=6.30, 95% CI: 1.60~24.82), housemate (OR=7.63, 95% CI: 2.58~22.52), exercise (OR=3.72, 95% CI: 1.37~10.12) in breast cancer examination, and age (OR=0.08, 95% CI: 0.02~0.34; OR=0.07, 95% CI: 0.01~0.85), personal medical insurance (OR=14.17, 95% CI: 2.94~68.23), sexual experiences (OR=3.38, 95% CI: 1.28~8.91), drinking (OR=2.92, 95% CI: 1.14~7.49) in cervical cancer examination. Conclusion: The results emphasize the necessity of preparing nursing education and intervention in consideration of associated factors which influence on the health examination in unmarried women.