• Title/Summary/Keyword: moderate effect

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Effects of Dietary Animal Protein and Plant Protein on Iron Bioavailability in Young Korean Women (동물성과 식물성단백질이 한국인 젊은여성의 체내 철분이용도에 미치는 영향)

  • 곽충실
    • Journal of Nutrition and Health
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    • v.27 no.5
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    • pp.451-459
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    • 1994
  • This study was performed to investigate the effect of sources of protein on iron bioavailability in 10 healthy young Korean women. The 18-day metabolic study consisted of a 6-day adaptation period, 6-day moderate protein(60g protein/day, 18mg Fe/day) and 6-day high protein period(90g protein/day, 18mg Fe/day). During the moderate and high protein period, 5 subjects were fed the high plant protein meals(80% plant protein). Fecal excretion of dietary iron was significantly higher(p<0.05) in high protein high plant diet group(HPP, 9.48$\pm$1.61mg/day) than in high protein high animal diet group (HPA, 14.40$\pm$0.89mg/day). Apparent absorption and bioavailability of iron was also significantly higher(p<0.10) in HPA(40.7$\pm$5.3%, 6.46$\pm$1.61mg/day) than in HPP(14.4$\pm$5.3%, 2.39$\pm$0.89mg/day). But there was no significant difference between the high animal protein group and high plant protein group in moderate protein period. Serum iron concentration and transferrin saturation increased as animal protein intake increased, from 106.0$\pm$5.1ug/이 and 30.6$\pm$1.5% for MPA to 129.1$\pm$6.7ug/이 and 37.1$\pm$1.3% for HPA. Statistically positive correlations were shown not only between the level of dietary heme iron and apparent absorption(r=0.95, p<0.05), but also between serum iron concentration and apparent absorption(r=0.64, p<0.05). Negative iron balance was shown in two subjects fed the moderate protein meals. These results suggest that recommanded dietary allowances of iron may be under the need to maintain the positive balance, and iron bioavaliability increase by only high level of animal protein intake.

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The Effect of Social Capital of Wage Workers with Acquired Disabilities on Organizational Commitment: Focusing on the Comparison of Degree of Disability (중도장애인 임금근로자의 사회적 자본이 조직몰입에 미치는 영향: 장애정도 비교 중심으로)

  • Kim, Soung-Wan
    • The Journal of the Korea Contents Association
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    • v.21 no.12
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    • pp.546-558
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    • 2021
  • This study aims to analyze the effects of the social capital of wage workers with acquired disabilities on organizational commitment, depending on the degree of their disabilities. The survey included 187 people with severe acquired disabilities and 606 people with moderate acquired disabilities, who participated in the 8th (2015) panel survey of employment for the disabled. Multiple regression analysis was performed: the results identified that the official network activity increased for people with both severe and moderate acquired disabilities and contributed to the improvement of organizational commitment. Further, women had a significant influence on organizational commitment. In the case of people with severe acquired disabilities, it was also found that, as social participation increased, organizational commitment decreased. In the case of people with moderate acquired disabilities, individuals who were healthier, more regular workers, and had higher qualifications had a greater positive the impact on the organizational commitment. Based on the results of this study, ways to increase social capital and organizational commitment of wage earners with severe and moderate acquired disabilities are suggested.

Effect of High Fat Diet and Calorie-restricted Diet on Protein Kinase C Activity in Mouse Epidermal Cell (고지방식이와 열량제한식이가 백서상피세포의 Protein Kinase C 활성에 미치는 영향)

  • Choe, Myeon
    • Journal of Nutrition and Health
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    • v.24 no.3
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    • pp.149-156
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    • 1991
  • To determine the effect of dietary fat and calorie level on protein kinase C(PKC) activity in mouse epidermal cells, female BALB/C mice (4weeks of age) were placed on high (24.6% ), moderate(5%) fat or calorie-restricted diets for at least 4 weeks. Diets were formulated on a nutrient/kcal basis such that the mice consumed the same amounts of protein. vitamins, minerals and fiber per kcal. PKC was assayed by the procedure of Wise et at. An apparent increase of PKC activity was observed from the aminal fed high fat diet when compared with the aminal fed moderate fat diet. PKC activity was decreased 40% by calorie restriction. In summary levels of dietary fat may contribute to mechanism of tumor promotion by increasing PKC activity in the mouse skin model.

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The Effect of an Exercise Program for Preventing Urinary Incontinence among Community-Dwelling Elderly Females Living Alone (일개 시 지역사회 거주 독거여성노인의 요실금예방 운동프로그램 중재효과)

  • Song, Mi Sook;Boo, Sunjoo
    • Journal of Korean Public Health Nursing
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    • v.30 no.2
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    • pp.247-258
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    • 2016
  • Purpose: The purpose of this study was to evaluate the effects of a comprehensive exercise program for the prevention of urinary incontinence (UI), frailty, and depression, as well as the promotion of physical function in community-dwelling elderly female living alone. Methods: A nonequivalent control group pretest-posttest design was employed. The participants were 76 vulnerable elderly female with a mild-to-moderate urinary incontinence. The exercise group completed 12 weeks of a moderate intensity, comprehensive exercise program. Descriptive statistics, independent t-tests and ANCOVA were used for data analysis with SPSS. Results: Upon the completion of the 12-week exercise program, significant improvements for UI symptoms (p=.001), timed up and go (p<.001), frailty (p=.006), and depression (p<.001) were observed, but not for hand grip strength (p=.053). Conclusion: The findings of this study indicate that the 12-week comprehensive exercise program for the prevention of urinary incontinence had positive effects on improving UI symptoms, physical function, levels of frailty and depression in elderly women living alone. More prolonged exercise programs with other types of exercise should be developed for these vulnerable elderly women, and future studies are encouraged to confirm the effect of the comprehensive exercise program in other settings.

Dietary Docosahexaenoic Acid Decreases Plasma Triglycerides with Mixed Effects on the Indices of $\beta$-oxidation

  • Cha, Youn-Soo
    • Journal of Nutrition and Health
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    • v.30 no.9
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    • pp.1067-1072
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    • 1997
  • One known effect of long chain n-3 polyunsaturated fatty acids is their ability to decrease plasma triglycerides. However, identification of the specific n-3 fatty acids and the underlying mechanisms responsible for this change remains uncertain. This present study was designed to evaluate the effects of moderate levels of dietary docosahexaenoic acid (22 :6(n-3)) on modulating plasma triglyderides. Male CD-1 mice were maintained for 15 days on identical diets containing either docosahexahexaenoic acid ethyl ester(1.5%, w/w) or linoleic acid(18 : 2(n-6)) ethyl ester (1.5%, w/w) . Plasma triglycerides were 40% lower in the docosahexaenoic acid group than in the linoleic acid group. Hepatic carnitine palmitoyltransferase activity (a key regulatory enzyme for mitocondria $\beta$-oxidation) was not significantly different between the dietary groups. However, plasma acid soluble acylcarnitine levels (which increase with increasing $\beta$-oxidation )were significantly higher in the decosahexaenoic acid group. This data suggests that plasma triglyceride levels are lower in mice fed diets containing moderate levels of docosahexaenoic acid compared to linoleic acid, but this effect on plasma triglycerides is not modulated through an augmentation of mitochondrial $\beta$-oxidation.

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Comparison of Breeding System Between Single Population and Two Sub-population Scheme by Computer Simulation II. Different genetic level for Sub-populations

  • Oikawa, T.;Matsura, Y.;Sato, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.4
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    • pp.428-434
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    • 1997
  • The effect of genetic diversity in sub-populations on breeding efficiency was examined with prospect of potential crossbreeding. Simulation study of selection was performed for 20 generations with 20 replications each, comparing average breeding values and inbreeding coefficients between the two breeding systemes; single population scheme and two population scheme. The different genetic levels were assumed to be caused by different gene frequencies. Phenotypes of two traits generated polygenic effect with additive 36 loci and residuals distributed normally were selected by selection index procedure. High genetic gain with less inbreeding was clearly recognized in the single population scheme, independently of difference in genetic level, economic weight and genetic correlation. Genetic correlation after selection in the single population scheme was lower than the two population scheme. When crossbreeding between the sub-population was taken into account, superiority of the two population scheme was suggested under those restrictions; difference in genetic level is moderate, selection criterion for the two traits is not far from even economic weight, and genetic correlation is positive with low to moderate value. The use of complementarity increased the possibility of the two population scheme.

An Experimental and Numerical Study on the Oxy-MILD Combustion at Pilot Scale Heating Capacity (Pilot급 산소 MILD 연소에 관한 실험 및 수치해석적 연구)

  • Cha, Chun-Loon;Lee, Ho-Yeon;Hwang, Sang-Soon
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.28 no.7
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    • pp.275-282
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    • 2016
  • MILD (Moderate and Intense Low-oxygen Dilution) combustion using oxygen as an oxidizer is considered as one of the most promising combustion technologies for high energy efficiency and for reducing nitrogen oxide and carbon dioxide emissions. In order to investigate the effects of nozzle angle and oxygen velocity conditions on the formation of oxygen-MILD combustion, numerical and experimental approaches were performed in this study. The numerical results showed that the recirculation ratio ($K_V$), which is an important parameter for performing MILD combustion, was increased in the main reaction zone when the nozzle angle was changed from 0 degrees to 15 degrees. Also, it was observed that a low and uniform temperature distribution was achieved at an oxygen velocity of 400 m/s. The perfectly invisible oxy-MILD flame was observed experimentally under the condition of a nozzle angle of $10^{\circ}$ and an oxygen velocity of 400 m/s. Moreover, the NOx emission limit was satisfied with NOx regulation of less than 80 ppm.

Anti-inflammatory Activity of Flavonoids from Populus davidiana

  • Zhang, XinFeng;Hung, Tran Manh;Phuong, Phuong Thien;Ngoc, Tran Minh;Min, Byung-Sun;Song, Kyung-Sik;Seong, Yeon-Hee;Bae, Ki-Hwan
    • Archives of Pharmacal Research
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    • v.29 no.12
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    • pp.1102-1108
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    • 2006
  • An in vitro bioassay-guide revealed that the methanol (MeOH) extract of the stem bark of Populus davidiana showed considerable inhibitory activity against cyclooxygenase (COX-1, COX-2). Continuous phytochemical study of the MeOH extract of this plant led to the isolation of ten flavonoids; sakuranetin (1), rhamnocitrin (2), 7-O-methylaromadendrin (3), naringenin (4), eriodictyol (5), aromadendrin (6), kaempferol (7), neosakuranin (8), sakuranin (9) and sakurenetin-5,4'-di-${\beta}$-D-glucopyranoside (10). Their structures were identified on the basis of their physicochemical and spectroscopic analyses. The isolated compounds, 1-10, were tested for their inhibitory activities against COX-1 and COX-2. Compound 7 was found to have potent inhibitory effect on COX-1 and a moderate effect on COX-2, meanwhile, compounds 1-6 showed moderate inhibition against COX-1 only. Moreover, compounds 5-8 exhibited suppressive effects on xanthine oxidase (XO). These results may explain, in part, the traditional uses of P. davidiana in ethnomedicine.

The Effect of Heparin on Prevention of Pericardial Adhesion - Experimental Study - (헤파린의 심막유착 방지효과에 관한 실험적 연구)

  • Song, In-Seok;Lee, Hong-Gyun
    • Journal of Chest Surgery
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    • v.19 no.1
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    • pp.12-17
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    • 1986
  • The pericardial adhesions following the first open heart surgery pose a major problem that can increase the morbidity and mortality in cases of reoperation because of the danger of damaging the heart, great vessels or grafts. The purpose of this study was to determine the effect of intrapericardial infusion of 5% dextrose solution and heparin on experimental pericardial adhesions. The 15 white rabbits were divided into three treatment groups of 5 animals each: group 1 [control group], group 2[5% dextrose group] and group 3 [heparin group]. At 4 weeks, all animals were sacrificed and the pericardial adhesions were graded as follows: 1[none], ll[mild], Ill[moderate] and IV[severe]. Histological examination was performed on a subset of each group. The difference of adhesion between control and heparin group was evaluated by Chi-square analysis. The results were as follows: 1. Pericardial adhesions developed in 80% of animals in group 1 and 2. 2. Only 40%> of animals in group 3 had mild to moderate pericardial adhesions. This was significantly different from the control group [P=0.01]. 3. Histological examination showed that the pericardium with adhesion was thickened with fibrosis, while that without adhesion was thin, normal appearance. 4. In group 3, there was no evidence of hemorrhage or hemorrhagic tendency in the pericardium.

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Does minimally invasive canal preparation provide higher fracture resistance of endodontically treated teeth? A systematic review of in vitro studies

  • Sila Nur Usta;Emmanuel Joao Nogueira Leal Silva;Seda Falakaloglu;Mustafa Gundogar
    • Restorative Dentistry and Endodontics
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    • v.48 no.4
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    • pp.34.1-34.12
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    • 2023
  • This systematic review aimed to investigate whether minimally invasive root canal preparation ensures higher fracture resistance compared to conventional root canal preparation in endodontically treated teeth (ETT). A comprehensive search strategy was conducted on the "PubMed, Web of Science, and Scopus" databases, alongside reference and hand searches, with language restrictions applied. Two independent reviews selected pertinent laboratory studies that explored the effect of minimally invasive root canal preparation on fracture resistance, in comparison to larger preparation counterparts. The quality of the studies was assessed, and the risk of bias was categorized as low, moderate, or high. The electronic search yielded a total of 1,767 articles. After applying eligibility criteria, 8 studies were included. Given the low methodological quality of these studies and the large variability of fracture resistance values, the impact of reduced apical size and/or taper on the fracture resistance of the ETT can be considered uncertain. This systematic review could not reveal sufficient evidence regarding the effect of minimally invasive preparation on increasing fracture resistance of ETT, primarily due to the inherent limitations of the studies and the moderate risk of bias.