• Journal of the Korean Society of Safety
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• v.38 no.3
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• pp.93-101
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• 2023

The COVID-19 pandemic has significantly impacted how people work, resulting in a massive shift towards working from home or remotely. Work from home has played a critical role in reducing the transmission of COVID-19 by limiting in-person interactions and reducing the density of people in office buildings. It also enabled businesses and organizations to continue operating while keeping their employees safe and healthy. The COVID-19 pandemic accelerated the adoption of work from home in business and organizational sectors worldwide, and it is likely to continue as a preferred mode of work even after the pandemic is over. This shift towards working from home has not only impacted the way people work but also has significant implications for urban development, transportation, and the environment. This study intends to develop measures for addressing potential physical and mental health issues among remotely working employees. Additionally, it identifies the major influencing factors of home workers' health hazards and proposes improvement measures that can be applied to working from home, along with existing laws and prevention methods.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.20 no.5
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• pp.593-604
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• 2007

Although composite construction has more mechanical advantages compared to noncomposite construction, the design of noncomposite construction for skew bridges with large skew angels has been often checked because composite construction may cause large stresses in the bridge deck. In this study, the analytical model considered dynamic behaviors for noncomposite skew bridges was proposed. Using the proposed analytical model, the validity of the application of noncomposite construction to skew bridges was checked. Also, the effects of interactions between the concrete deck and steel girders such as composite construction, partial composite construction, and noncomposite construction on the dynamic characteristics and dynamic behaviors of simply supported skew bridges were investigated. A series of parametric studies for the total 27 skew bridges was conducted with respect to parameters such as girder spacing, skew angle, and deck aspect ratio. Although the slip at the interfaces between the concrete deck and steel girders results in the reduction of seismic total base shear in the transverse direction due to period elongation, it causes an undesirable behavior of skew bridges by the modification in mode shapes and distributions of stiffness. Shear connectors placed by minimum requirements for partial composite action have an effect on reducing the girder stresses and deck stresses; except case of some skew bridges, the magnitude of the girder stresses and deck stresses obtained from partial composite skew bridges is similar to or slightly more than those acquired from composite skew bridges.

• The Journal of the Convergence on Culture Technology
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• v.10 no.4
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• pp.563-574
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• 2024

While the integration of chatbot and the simplification of financial terminology in Financial services' apps are increasingly common, automotive finance apps often show lower user satisfaction for complex terminol- ogy and rigid content. This study investigates the effects of chatbot interaction modes and the simplification of financial terminology on user experience in automotive finance apps. We developed prototypes for car lease tasks under different conditions: the type of user interaction channel (chatbot vs menu-based), and the usage of financial terminology. A 2 x 2 experimental survey was conducted to measure perceptions of friendliness, read- ability, trust, and accuracy. The findings revealed that chatbot interactions significantly enhance friendliness more than menu-based interactions, and simplifying terminology significantly improves readability and friendliness. However, no significant differences were observed in trust and accuracy between the conditions. Furthermore, nosignificant interaction effects were found between the two conditions across all variables. This study contributes by quantitatively assessing the impacts of chatbot consultation modes and terminology sim- plification on customer experience in financial services.

• Journal of Korea Entertainment Industry Association
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• v.13 no.1
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• pp.47-57
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• 2019

The end of the 20th century, along with the popularity of new media technology and the rise of new media art, dance as a visual art, and body language art, has the features of more and more rich and changeful. In today's Internet booming new media environment, many different fields, such as film and theater, computer technology, digital art, etc.) with its commonness and characteristics of all kinds of interaction between the creation, produced a new interdisciplinary research with theoretical model. When cross-border interactions between various areas become a hot topic at the same time, the traditional form of dance performances are also seeking new breakthrough. Canada's famous social psychologist McLuhan believes that modern is retrieving lost over a long period of time "overall" feel, return to a feeling of equilibrium. The audience how to have the characteristics of focus on details of visual art back to the "overall" feel worthy of study. At the same time, the new media in today's digital dance teaching in colleges and universities dancing education remains to be perfect and popular, if continue to use the precept of the traditional teaching way blindly, so it is difficult to get from the development of the current domestic dance overall demand. In this paper, the main body is divided into two parts, the first chapter is the study of image device dance performance art, the second chapter is the research of digital dance teaching application system, thus further perspective of media technology to explore dance art crossover practice under the new media environment and mode of transmission.

• Journal of the Korea Computer Industry Society
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• v.7 no.5
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• pp.521-536
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• 2006

The Blended Learning of K-12 education can he complimented to exceed the limits of the traditional face-to-face instructional method and can help learners have experiences with both various interactions and different learning experiences. Specifically, in K-12 education blended learning has a strength in being able to integrate on-line instruction with off-line instruction and actively help learners emerge with a breadth of knowledge gained collaboratively.<중략>For the objective of the study, that is, an investigation by a literature review process, the mode) of the process of collaboratively emerging knowledge as well as the alternative model of the concept can be applied as a developmental research method, which can improve practical procedure, process, and prescription. For overcoming the model and the real situation, this study was applied with Checkland(1999)'s soft system methodology, using$\square$the comparison of the model and real situations$\square$part and$\square$defining the alternatives$\square$of Checkland(1999)'s methods. In conclusion, analyzing the conceptual model and real situation helps in the development of a model which can minimize the discrepancy between the conceptual model and the real situation within K-12 education.

• Proceedings of the Korean Society of Plant Pathology Conference
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• 2003.10a
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• pp.122-123
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• 2003

Apple stem grooving virus (ASGV) belongs to Capillovirus and infects pome fruits. Transmission mode of ASGV is known by grafting and mechanical inoculation into susceptible hosts, not by any other natural vectors. But we have observed the spread of ASGV in the field without mechanical inoculation or grafting. Transmission seems to be occurred from tree-to-tree and tree-to-susceptible herbaceous plants along but not across ditches in the field. In order to ascertain this possibility, various fungi were isolated and cultured from ASGV-infected plants and 69 isolates were characterized. By means of RNA dot-blot hybridization and PCR analysis, 3 isolates were sorted out for further studies. The isolates were identified to Tataromyces sp. and belonged to Phenicillium by morphological characteristics and molecular markers. As an experimental host, 10 kidney beans (Phaseolus vulgaris) were screened and Kyunggi-5 was selected for virus amplification and symptom development. Kyunggj-5 infected by fungi which seemed to carry ASGV showed the typical disease symptoms and viral coat protein genes were detected from all tested plants. To confirm the Koch's rule, fungi cultured from inoculation origins of kidney bean were grown on PDA media and re-inoculated to hosts. The fungi isolated from inoculation origins induced the typical disease symptoms on hosts. However virus free fungi did not induce any symptom on the experimental hosts. This bioassay showed that these typical symptoms were caused by virus, not fungi.

• CELLMED
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• v.4 no.1
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• pp.6.1-6.12
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• 2014

Anthrax is the deadly disease for human being caused by Bacillus anthracis. Instantaneous research work on the mode of infection of the organism revealed that different proteases are involved in different steps of pathogenesis. Present study reports the in silico characterization and the detection of pathogenic proteases involved in anthrax infection through protein-protein interaction. A total of 13 acid, 9 neutral, and 1 alkaline protease of Bacillus anthracis were selected for analysing the physicochemical parameter, the protein superfamily and family search, multiple sequence alignment, phylogenetic tree construction, protein-protein interactions and motif finding. Among the 13 acid proteases, 10 were found as extracellular enzymes that interact with immune inhibitor A (InhA) and help the organism to cross the blood brain barrier during the process of infection. Multiple sequence alignment of above acid proteases revealed the position 368, 489, and 498-contained 100% conserved amino acids which could be used to deactivate the protease. Among the groups analyzed, only acid protease were found to interact with InhA, which indicated that metalloproteases of acid protease group have the capability to develop pathogenesis during B. anthracis infection. Deactivation of conserved amino acid position of germination protease can stop the sporulation and germination of B anthracis cell. The detailed interaction study of neutral and alkaline proteases could also be helpful to design the interaction network for the better understanding of anthrax disease.

• Composites Research
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• v.18 no.1
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• pp.23-29
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• 2005

In this work, the effect of ozone treatment of montmorillonite (MMT) on the surface characteristics of montmorillonite and the thermal stability of MMT/polypropylene (PP) nanocomposites was investigated. The surface properties of MMT were determined by X-ray diffraction (XRD), Fourier transform infrared (FT-IR), and X-ray photoelectron spectroscopy (XPS). Also, the thermal stability of nanocomposites was investigated in thermogravimetric analysis (TGA). As a result, it was found that the silicate interlayers of the organically modified MMT (D-MMT) were increased by about 11${\AA}$, as compared with the MMT. Also, FT-IR showed that a new peaks at $2800\~2900\;cm^{-1}$ appeared due to the $CH_2$ mode in the D-MMT The ozone treatment of the MMT led to an increase of SiO or $SiO_2$ groups on MMT surfaces, resulting in increasing the oxygen-containing functional groups on MMT. The ozonized MMT had higher thermal stability than that of untreated nanocomposites. This was due to the improvement of interfacial bonding strengths, resulting from the acid-base interfacial interactions between PP and MMT.

• Biomolecules & Therapeutics
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• v.21 no.5
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• pp.371-380
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• 2013

Doxorubicin is still main drug in chemotherapy with limitation of use due to adverse drug reaction. Increased oxidative stress and alteration of nitric oxide control have been involved in cardiotoxicity of doxorubicin (DOX). A Disintegrin And Metalloproteinase (ADAMs) are transmembrane ectoproteases to regulate cell-cell and cell-matrix interactions, but role in cardiac disease is unclear. The aim of this study was to determine whether DOX activates peroxynitrite and ADAM 10 and thus ADAM and matrix metalloproteinase (MMP) induce cardiac remodeling in DOX-induced cardiomyopathy. Adult male Sprague-Dawley rats were subjected to cardiomyopathy by DOX (6 times of 2.5 mg/kg DOX over 2-weeks), and were randomized as four groups. Then followed by 3, 5, 7, and 14 days after cessation of DOX injection. DOX-injected animals significantly decreased left ventricular fractional shortening compared with control by M-mode echocardiography. The expressions of cardiac nitrotyrosine by immunohistochemistry were significant increased, and persisted for 2 weeks following the last injection. The expression of eNOS was increased by 1.9 times (p<0.05), and iNOS was marked increased in DOX-heart compared with control (p<0.001). Compared to control rats, cardiac ADAM10- and MMP 9- protein expressions increased by 20 times, and active/total MMP 9 proteolytic activity showed increase tendency at day 14 after cessation of DOX injection (n=10, each group). DOX-treated $H_9C_2$ cell showed increased ADAM10 protein expression with dose-dependency (p<0.01) and morphometric changes showed the increase of ventricular interstitial, nonvascular collagen deposition. These data suggest that activation of cardiac peroxynitrite with increased iNOS expression and ADAM 10-dependent MMP 9 expression may be a molecular mechanism that contributes to left ventricular remodeling in DOXinduced cardiomyopathy.

• Microbiology and Biotechnology Letters
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• v.33 no.1
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• pp.9-15
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• 2005

Chitin deacetylase (CDA; EC 3.5.1.41) catalyzes the hydrolysis of N-acetamide bonds of chitin, converting it to chitosan. Chitosan has several applications in areas such as biomedicine, food ingredients, cosmetics, pharmaceuticals, and agriculture. In this paper, occurrence, assay and purification protocols, enzymatic characteristics, substrate specificity, and mode of action of microbial CDAs have been described. Several lines of evidence have substantiated the biological roles involved in cell wall formation and plant-pathogen interactions for fungal CDAs. The gene structure of CDAs has been compared with other family 4 carbohydrate esterases which deacetylate a wide variety of acetylated poly/oligo-saccharides. The use of CDAs for the conversion of chitin to chitosan, in contrast to the presently used chemical procedure, offers the possibility of a controlled, non-degradable process, resulting in the production of well-defined chitosan oligomers and polymers. Insect pathogen that can secrete high levels of chitin-metab­olizing enzymes including CDA can be a possible alternative for new pest management tools.