• Title/Summary/Keyword: mixture 모델

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Simultaneous Spectrophotometric Determination of Copper, Nickel, and Zinc Using 1-(2-Thiazolylazo)-2-Naphthol in the Presence of Triton X-100 Using Chemometric Methods (화학계량학적 방법을 사용한 Triton X-100이 함유된 1-(2-Thiazolylazo)-2-Naphthol을 사용한 구리, 니켈과 아연의 동시 분광광도법적 정량)

  • Low, Kah Hin;Zain, Sharifuddin Md.;Abas, Mhd. Radzi;Misran, Misni;Mohd, Mustafa Ali
    • Journal of the Korean Chemical Society
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    • v.53 no.6
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    • pp.717-726
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    • 2009
  • Multivariate models were developed for the simultaneous spectrophotometric determination of copper (II), nickel (II) and zinc (II) in water with 1-(2-thiazolylazo)-2-naphthol as chromogenic reagent in the presence of Triton X-100. To overcome the drawback of spectral interferences, principal component regression (PCR) and partial least square (PLS) multivariate calibration approaches were applied. Performances were validated with several test sets, and their results were then compared. In general, no significant difference in analytical performance between PLS and PCR models. The root mean square error of prediction (RMSEP) using three components for $Cu^{2+}$, $Ni^{2+}$ and $Zn^{2+}$ were 0.018, 0.010, 0.011 ppm, respectively. Figures of merit such as sensitivity, analytical sensitivity, limit of detection (LOD) were also estimated. High reliability was achieved when the proposed procedure was applied to simultaneous determination of $Cu^{2+}$, $Ni^{2+}$ and $Zn^{2+}$ in synthetic mixture and tap water.

Development of Low-fat Meat Processing Technology Using Interactions between Meat Proteins and Hydrocolloids- I Optimization of Interactions between Meat Proteins and Hydrocolloids by Model Study (식육단백질과 친수성 콜로이드의 상호결합 특성을 이용한 저지방 육제품 제조기술 개발 - I 모델연구를 이용한 상호반응의 최적화)

  • Chin, Koo-Bok;Chung, Bo-Kyung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.3
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    • pp.438-444
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    • 2002
  • Interactions between meat proteins and hydrocolloids in a model system may play an important role for the improvement of textural properties in low-fat sausage mixtures. The objective of this study was to determine gel properties as affected by the type and level of hydrocolloid, various pH values of meat protein-hydrocolloid mixture before cooking, and internal cooking temperatures. The desirable heat-induced gels (HIGs) were formed at least pH values above 6.0. The addition of konjac flour (KF), kappa-carrageenan (CN) and locust bean gum (LBG) to extracted salt soluble proteins (2%) improved the gel strength with increased levels (0.5∼1.5%) and HIGs containing CN had the highest (p<0.05) gel strength. The increase of cooking temperature increased gel strength, depending on pH and type of hydrocolloid. However, the minimun internal cooking temperature to make viscoelastic HIGs was 70$^{\circ}C$. These results indicated that desirable HIGs were manufactured with each hydrocolloid concentration of 1% and minimum cooking temperature of 70$^{\circ}C$ with pH values higher than 6.0.

Fracture and Hygrothermal Effects in Composite Materials (복합재의 파괴와 hygrothermal 효과에 관한 연구)

  • Kook-Chan Ahn;Nam-Kyung Kim
    • Journal of the Korean Society of Safety
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    • v.11 no.4
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    • pp.143-150
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    • 1996
  • This is an explicit-Implicit, finite element analysis for linear as well as nonlinear hygrothermal stress problems. Additional features, such as moisture diffusion equation, crack element and virtual crack extension(VCE ) method for evaluating J-integral are implemented in this program. The Linear Elastic Fracture Mechanics(LEFM) Theory is employed to estimate the crack driving force under the transient condition for and existing crack. Pores in materials are assumed to be saturated with moisture in the liquid form at the room temperature, which may vaporize as the temperature increases. The vaporization effects on the crack driving force are also studied. The Ideal gas equation is employed to estimate the thermodynamic pressure due to vaporization at each time step after solving basic nodal values. A set of field equations governing the time dependent response of porous media are derived from balance laws based on the mixture theory Darcy's law Is assumed for the fluid flow through the porous media. Perzyna's viscoplastic model incorporating the Von-Mises yield criterion are implemented. The Green-Naghdi stress rate is used for the invariant of stress tensor under superposed rigid body motion. Isotropic elements are used for the spatial discretization and an iterative scheme based on the full newton-Raphson method is used for solving the nonlinear governing equations.

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Waveform Decomposition of Airborne Bathymetric LiDAR by Estimating Potential Peaks (잠재적 피크 추정을 통한 항공수심라이다 웨이브폼 분해)

  • Kim, Hyejin;Lee, Jaebin;Kim, Yongil;Wie, Gwangjae
    • Korean Journal of Remote Sensing
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    • v.37 no.6_1
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    • pp.1709-1718
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    • 2021
  • The waveform data of the Airborne Bathymetric LiDAR (ABL; LiDAR: Light Detection And Ranging) system provides data with improved accuracy, resolution, and reliability compared to the discrete-return data, and increases the user's control over data processing. Furthermore, we are able to extract additional information about the return signal. Waveform decomposition is a technique that separates each echo from the received waveform with a mixture of water surface and seabed reflections, waterbody backscattering, and various noises. In this study, a new waveform decomposition technique based on a Gaussian model was developed to improve the point extraction performance from the ABL waveform data. In the existing waveform decomposition techniques, the number of decomposed echoes and decomposition performance depend on the peak detection results because they use waveform peaks as initial values. However, in the study, we improved the approximation accuracy of the decomposition model by adding the estimated potential peak candidates to the initial peaks. As a result of an experiment using waveform data obtained from the East Coast from the Seahawk system, the precision of the decomposition model was improved by about 37% based on evaluating RMSE compared to the Gaussian decomposition method.

A development of multivariate drought index using the simulated soil moisture from a GM-NHMM model (GM-NHMM 기반 토양함수 모의결과를 이용한 합성가뭄지수 개발)

  • Park, Jong-Hyeon;Lee, Joo-Heon;Kim, Tae-Woong;Kwon, Hyun Han
    • Journal of Korea Water Resources Association
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    • v.52 no.8
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    • pp.545-554
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    • 2019
  • The most drought assessments are based on a drought index, which depends on univariate variables such as precipitation and soil moisture. However, there is a limitation in representing the drought conditions with single variables due to their complexity. It has been acknowledged that a multivariate drought index can more effectively describe the complex drought state. In this context, this study propose a Copula-based drought index that can jointly consider precipitation and soil moisture. Unlike precipitation data, long-term soil moisture data is not readily available so that this study utilized a Gaussian Mixture Non-Homogeneous Hidden Markov chain Model (GM-NHMM) model to simulate the soil moisture using the observed precipitation and temperature ranging from 1973 to 2014. The GM-NHMM model showed a better performance in terms of reproducing key statistics of soil moisture, compared to a multiple regression model. Finally, a bivariate frequency analysis was performed for the drought duration and severity, and it was confirmed that the recent droughts over Jeollabuk-do in 2015 have a 20-year return period.

Numerical Study of Combustion Characteristics by Pressure and Oxygen Concentration in Counter-Flow Diffusion Flame Model (대향류 확산 화염 모델에서의 압력 및 산소분율에 따른 연소 특성 변화에 관한 수치해석 연구)

  • Park, Jinje;Lee, Youngjae
    • Clean Technology
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    • v.27 no.1
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    • pp.93-103
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    • 2021
  • As the seriousness and necessity of responding to climate change and reducing carbon emissions increases, countries around the world are continuing their efforts to reduce greenhouse gases. Among various efforts, research on CCUS, capturing and utilizing carbon dioxide generated when using carbon-based fuels, is actively being conducted. Studies on pressurized oxy-fuel combustion (POFC) that can be used with CCUS are also being conducted by many researchers. The purpose of this study is to analyze basic information related to the flame structure and pollutant emissions of pressurized oxy-fuel combustion. For this, a counter-flow diffusion flame model was used to analyze the combustion characteristics according to pressure and oxygen concentration. As the pressure increased, the flame temperature increased and the flame thickness decreased due to a reaction rate improvement caused by the activation of the chemical reaction. As oxygen concentration increased, both the flame temperature and the flame thickness increased due to an improvement to the reaction rate and diffusion because of a change in oxidizer momentum. Analyzing the related heat release reaction by dividing it into three sections as the oxygen concentration increased showed that the chemical reaction from the oxidizer side was subdivided into two regions according to the mixture fraction. In addition, the emission index of NO classified according to the NO formation mechanism was analyzed. The formation trend of NO according to each analysis condition was presented.

Evaluation of the efficacy of modified Samultang in female menopausal animal models using ovarian resection rats (난소절제 랫드를 이용한 여성갱년기 동물모델에서 변형 사물탕의 효능평가)

  • Hwang, Seonghee;Park, Sunyoung;Shin, Yong Kook
    • Journal of the Korea Convergence Society
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    • v.13 no.4
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    • pp.573-582
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    • 2022
  • In order to develop samultang with reduced side effects, modified samultang using omija was oral administered to rats with ovarian resection, and changes in evaluation indicators of functional efficacy in women's menopause were measured. In weight gain, relative weight of uterus and vagina, blood lipid-related indicators, and changes in blood estradiol, there was no statistically significant improvement effect in modified Samultang compared to the control group. However, the expression of estrogen receptor alpha and beta in intrauterine tissue tended to increase, and the expression of phosphorylated ERK, which is known to be involved in estrogen receptor signaling, showed a significant increase in activation in ERK and AKT. The expression amount of phosphorylation AKT was not significant, but showed an increasing tendency. Even though the test substance was administered in a relatively small dose, it is judged that the test substance modified Samultang has the ability to activate estrogen receptor. In the future, it is expected that it can be used as a useful natural mixture to show the efficacy of samultang with fewer gastrointestinal disorders.

Numerical Study of Heat Flux and BOG in C-Type Liquefied Hydrogen Tank under Sloshing Excitation at the Saturated State (포화상태에 놓인 C-Type 액체수소 탱크의 슬로싱이 열 유속과 BOG에 미치는 변화의 수치적 분석)

  • Lee, Jin-Ho;Hwang, Se-Yun;Lee, Sung-Je;Lee, Jang Hyun
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.35 no.5
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    • pp.299-308
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    • 2022
  • This study was conducted to predict the tendency for heat exchange and boil-off gas (BOG) in a liquefied hydrogen tank under sloshing excitation. First, athe fluid domain excited by sloshing was modeled using a multiphase-thermal flow domain in which liquid hydrogen and hydrogen gas are in the saturated state. Both the the volume of fluid (VOF) and Eulerian-based multi-phase flow methods were applied to validate the accuracy of the pressure prediction. Second, it was indirectly shown that the fluid velocity prediction could be accurate by comparing the free surface and impact pressure from the computational fluid dynamics with those from the experimental results. Thereafter, the heat ingress from the external convective heat flux was reflected on the outer surfaces of the hydrogen tank. Eulerian-based multiphase-heat flow analysis was performed for a two-dimensional Type-C cylindrical hydrogen tank under rotational sloshing motion, and an inflation technique was applied to transform the fluid domain into a computational grid model. The heat exchange and heat flux in the hydrogen liquid-gas mixture were calculated throughout the analysis,, whereas the mass transfer and vaporization models were excluded to account for the pure heat exchange between the liquid and gas in the saturated state. In addition, forced convective heat transfer by sloshing on the inner wall of the tank was not reflected so that the heat exchange in the multiphase flow of liquid and gas could only be considered. Finally, the effect of sloshing on the amount of heat exchange between liquid and gas hydrogen was discussed. Considering the heat ingress into liquid hydrogen according to the presence/absence of a sloshing excitation, the amount of heat flux and BOG were discussed for each filling ratio.

Operating Optimization and Economic Evaluation of Multicomponent Gas Separation Process using Pressure Swing Adsorption and Membrane Process (압력 순환 흡착과 막 분리공정을 이용한 다성분 기체의 분리공정 조업 최적화 및 경제성 평가)

  • Kim, Hansol;Lee, Jaewook;Lee, Soobin;Han, Jeehoon;Lee, In-Beum
    • Korean Chemical Engineering Research
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    • v.53 no.1
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    • pp.31-38
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    • 2015
  • At present, carbon dioxide ($CO_2$) emission, which causes global warming, is a major issue all over the world. To reduce $CO_2$ emission directly, commercial deployment of $CO_2$ separation processes has been attempted in industrial plants, such as power plant, oil refinery and steelmaking plant. Besides, several studies have been done on indirect reduction of $CO_2$ emission from recycle of reducing gas (carbon monoxide or hydrogen containing gas) in the plants. Unlike many competing gas separation technologies, pressure swing adsorption (PSA) and membrane filtration are commercially used together or individually to separate a single component from the gas mixture. However, there are few studies on operation of sequential separation process of multi-component gas which has more than two target gas products. In this paper, process simulation model is first developed for two available configurations: $CO_2$ PSA-CO PSA-$H_2$ PSA and $CO_2$ PSA-CO PSA-$H_2$ membrane. Operation optimization and economic evaluation of the processes are also performed. As a result, feed gas contains about 14% of $H_2$ should be used as fuel than separating $H_2$, and $CO_2$ separation should be separated earlier than CO separation when feed gas contains about 30% of $CO_2$ and CO. The simulation results can help us to find an optimal process configuration and operation condition for separation of multicomponent gas with $CO_2$, CO, $H_2$ and other gases.

Cerebrolysin Attenuates Astrocyte Activation Following Repetitive Mild Traumatic Brain Injury: Implications for Chronic Traumatic Encephalopathy (만성외상성뇌병증과 관련된 반복적 경도 외상성뇌손상(rmTBI)모델에서 cerebrolysin의 별아교 세포활성 억제효과)

  • Kang, Hyun Bae;Kim, GiHun;Kim, HyunJoong;Han, Sa Rang;Chae, Dong Jin;Song, Hee-Jung;Kim, Dong Woon
    • Journal of Life Science
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    • v.23 no.9
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    • pp.1096-1103
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    • 2013
  • Chronic traumatic encephalopathy (CTE), which is common in athletes, is a progressive neurodegenerative disease and a long-term consequence of repetitive closed head injuries. CTE is regarded as a chronic brain syndrome due to the effects of repetitive traumatic brain injury (TBI). Because neurotrophic factors are neuroprotective in models of brain and spinal cord injuries, we examined the effects of cerebrolysin, a mixture of various neurotrophic factors, on brain pathology in a mouse model of repetitive mild TBI (rmTBI), which is a good model of CTE. Five groups were created and treated as follows: groups 1 and 2: rmTBI for 4 weeks following cerebrolysin injection for 4 weeks; groups 3 and 4: rmTBI for 8 weeks with or without cerebrolysin injection for 4 weeks; group 5: control. We found that p-tau expression was increased in the pyramidal layer of the cortex and hippocampus, particularly the CA3 region, but not in the CA1 region and the dentate gyrus (DG). Intra-tail vein administration of cerebrolysin ($10{\mu}l$ of 1 mg/ml) after/during rmTBI treatment reduced p-tau expression in both the cortex and hippocampus. Histological analysis revealed mild astrocyte activation (increased expression of glial fibrillary acidic protein (GFAP)) but not microglia activation (ionized calcium binding adaptor molecule 1 (iba-1) expression) and peripheral macrophage infiltration (CD45). Additionally, administration of cerebrolysin after rmTBI resulted in reduced astrocyte activation. These observations in rmTBI demonstrated that cerebrolysin treatment reduces phosphorylation of tau and astrocyte activation, attenuates brain pathology, and mitigates function deficits in TBI. Taken together, our observations suggest that cerebrolysin has potential therapeutic value in CTE.