• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2006년도 추계 학술발표회 논문집
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• pp.909-912
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• 2006

This paper examined the applicability of convex hull, which is defined as the minimal convex polygon including all points, to assessment model for effective region. In order to validate the applicability of the convex hull to assessment model for effective region, a genetic algorithm was adopted as a optimum technique, and an artificial neural network was adopted as a prediction model for material properties. The mix-proportion obtained from the proposed technique is more reasonable than that obtained from previous work.

• IMMUNE NETWORK
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• 제12권6호
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• pp.269-276
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• 2012

The anti-tumor effect of monocyte-derived DC (MoDC) vaccine was studied in lung cancer model with feasible but weak Ag-specific immune response and incomplete blocking of tumor growth. To overcome this limitation, the hematopoietic stem cell-derived DC (SDC) was cultured and the anti-tumor effect of MoDC & SDC was compared in mouse lung cancer minimal residual model (MRD). Therapeutic DCs were cultured from either $CD34^+$ hematopoietic stem cells with GM-CSF, SCF and IL-4 for 14 days (SDC) or monocytes with GM-CSF and IL-4 for 7 days (MoDC). DCs were injected twice by one week interval into the peritoneum of mice that are inoculated with Lewis Lung Carcinoma cells (LLC) one day before the DC injection. Anti-tumor responses and the immune modulation were observed 3 weeks after the final DC injection. CD11c expression, IL-12 and TGF-${\beta}$ secretion were higher in SDC but CCR7 expression, IFN-${\gamma}$ and IL-10 secretion were higher in MoDC. The proportion of $CD11c^+CD8a^+$ cells was similar in both DC cultures. Although both DC reduced the tumor burden, histological anti-tumor effect and the frequencies of IFN-${\gamma}$ secreting $CD8^+$ T cells were higher in SDC treated group than in MoDC. Conclusively, although both MoDC and SDC can induce the anti-tumor immunity, SDC may be better module as anti-tumor vaccine than MoDC in mouse lung cancer.

• 한국수학사학회지
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• 제21권3호
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• pp.1-30
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• 2008

뉴턴의 중력이론의 성공은 수학물리학을 태동시키는 바, 최초로 19세기 초의 분자력의 모델성립에 중요한 요소로 등장하였다. 라플라스는 여기서 회전타원체의 작용이라는 모델을 이용하였고 회전타원체의 작용은 이계편미분방정식으로 표현이 되었다. 이것을 풀어서 유체를 담은 용기의 기하학적 모습과 와 유체와 고체의 접촉각에 대응시켰다. 알 수 없는 분자간거리는 추상적이고 미지의 힘 함수 $\varphi(f)$를 써서 표현하여, 분자 작용반경이라는 개념을 도입하여 이론적인 포텐셜 함수의 이론적인 토대를 구축하였다. 뉴턴의 중력이론은 라플라스이론에서 완성을 이루었고, 이후 분자력의 모델로서 작용을 하였다. 라플라스-영의 모세관이론은 수학적으로는 극소 곡면론에서 물리학적으로는 표면장력현상으로 설명이 된다.

• 인터넷정보학회논문지
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• 제7권1호
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• pp.121-130
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• 2006

차세대 무선 네트워크에서는 응용들이 실시간 선불 서비스를 제공해야 하며, 최종 사용자에게 서비스를 제공하기 이전에 요청된 서비스에 대해 신용을 사전 체크하여야 한다. 또한 선불서비스를 효과적으로 제공하기 위해서는 신용제어 기능이 최소한의 지연만을 가져야 한다. 본 논문에서는 모바일 IPv6 환경에서 실시간 신용제어가 가능한 권한검증 구현 모델을 제안하였다. 제안한 모델은 일반적인 신용제어 권한검증 절차와 모바일 IPv6 인증 절차를 통합한 구조를 갖는다. 지연을 최소화하기 위해 제안한 모델을 싱글 서버 내에 구현하였으며, 이 시스템은 권한검증과 인증을 동시에 수행한다. 구현한 시스템의 구현구조를 소프트웨어 기능 블록과 유니트 형태로 제시하였다. 구현한 모델의 feasibility를 검증하기 위해서 구현한 시스템의 지연을 측정하였으며 측정 시, 몇 가지 인증 확장 프로토콜 (EAP)을 적용하였다. 측정된 결과에 따르면 신용제어 권한검증과 인증이 분리된 기존 모델과 비해서 제안한 통합 모델이 상대적으로 지연시간이 적었다.

• 산업경영시스템학회지
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• 제41권2호
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• pp.24-31
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• 2018

As a system complexity increases and technology innovation progresses rapidly, leasing the equipment is considered as an important issue in many engineering areas. In practice, many engineering fields lease the equipment because it is an economical way to lease the equipment rather than to own the equipment. In addition, as the maintenance actions for the equipment are costly and need a specialist, the lessor is responsible for the maintenance actions in most leased contract. Hence, the lessor should establish the optimal maintenance strategy to minimize the maintenance cost. This paper proposes two periodic preventive maintenance policies for the leased equipment. The preventive maintenance action of policy 1 is performed with a periodic interval, in which their intervals are the same until the end of lease period. The other policy is to determine the periodic preventive maintenance interval minimizing total maintenance cost during the lease period. In addition, this paper presents two decision-making models to determine the preventive maintenance strategy for leased equipment based on the lessor's preference between the maintenance cost and the reliability at the end of lease period. The structural properties of the proposed decision-making model are investigated and algorithms to search the optimal maintenance policy that are satisfied by the lessor are provided. A numerical example is provided to illustrate the proposed model. The results show that a maintenance policy minimizing the maintenance cost is selected as a reasonable decision as the lease term becomes shorter. Moreover, the frequent preventive maintenance actions are performed when the minimal repair cost is higher than the preventive maintenance cost, resulting in higher maintenance cost.

• 한국신뢰성학회지:신뢰성응용연구
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• 제7권1호
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• pp.13-22
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• 2007

A preventive maintenance model, caller FNBM (${\alpha},{\delta},{\gamma}$) model, is proposed to decide an optimal repair number under achieved availability requirements (r) along with taking two types of failures (repairable or irrepairable) into account. In this model, the current system is replaced by a new one in case when it doesn't meet the achieved availability requirement, even though it is repairable failure; Othewise it is replaced in time of the first irrepairable failure. Assumed that the j-th failure is repairable with probability ${\alpha}_j$ minimal repairs are allowed for repairable failure between replacements. Expected cost rate for preventive maintenance model is developed using NHPP (Non - Homogeneous Poisson Process) in order to de term in the optimal number $n^*$, also numerical examples are shown in order to explain the proposed model. Since the proposed FNBM (${\alpha},{\delta},{\gamma}$) model includes Park FNBM model (1979) and Nakagawa FNBM (p) model (1983) m this proposed model is thought to be better than previous model, especially for weapon system which requires availability as primary parameter.

• Communications for Statistical Applications and Methods
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• 제25권2호
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• pp.131-157
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• 2018

We propose a robust event date model to estimate the date of a target event by a combination of individual dates obtained from archaeological artifacts assumed to be contemporaneous. These dates are affected by errors of different types: laboratory and calibration curve errors, irreducible errors related to contaminations, and taphonomic disturbances, hence the possible presence of outliers. Modeling based on a hierarchical Bayesian statistical approach provides a simple way to automatically penalize outlying data without having to remove them from the dataset. Prior information on individual irreducible errors is introduced using a uniform shrinkage density with minimal assumptions about Bayesian parameters. We show that the event date model is more robust than models implemented in BCal or OxCal, although it generally yields less precise credibility intervals. The model is extended in the case of stratigraphic sequences that involve several events with temporal order constraints (relative dating), or with duration, hiatus constraints. Calculations are based on Markov chain Monte Carlo (MCMC) numerical techniques and can be performed using ChronoModel software which is freeware, open source and cross-platform. Features of the software are presented in Vibet et al. (ChronoModel v1.5 user's manual, 2016). We finally compare our prior on event dates implemented in the ChronoModel with the prior in BCal and OxCal which involves supplementary parameters defined as boundaries to phases or sequences.

• 대한한방부인과학회지
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• 제20권4호
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• pp.123-131
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• 2007

Purpose: To find the correlation between ambient temperature change and the efficacy of acupuncture on the postmenopausal hot flash. Methods: 52 patients entered a randomized clinical trial which was to verify the efficacy of acupuncture on postmenopausal hot flash. Participants were treated with optimal/minimal acupuncture in the course of 13 weeks. 34 of 52 visited for the temperature-rising period(Group 1), while 18 of 52 for the temperature-falling period(Group 2), 100mm hot flash VAS and average temperature were taken 18 times from each person. Linear mixed effects model was used to find the correlation between temperature and hot flash VAS score(p-value<0.05). Group1/2, optimal/minimal acupuncture, age, age of menarche, height, weight, percent body fat, BMI, waist-hip ratio, past history of hysterectomy and HRT were also examined. Results: Period of treatment had influence on the hot flash VAS. As time went by, hot flash decreased(p<.0000). Participants who underwent minimal acupuncture showed higher hot flash VAS(p=0.0479) and as waist-hip ratio rose, hot flash increased(p<.0000). As the temperature rose, hot flash VAS score became lower(p=0.0143) and it was because 34 of 52 participants were treated for the temperature-rising period. Group 1/2 had no interrelation with hot flash(p=0.5741). Conclusion: Hot flash diminished as participants were treated with acupuncture, independently of whether the ambient temperature rises or falls.

• International Journal of Control, Automation, and Systems
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• 제3권4호
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• pp.631-639
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• 2005

In this paper, we propose a constructive realization procedure for 2D systems which may lead to a Fornasini-Marchesini local state-space model with much lower order than the existing realization procedure given by Bisiacco et al. Nontrivial examples are illustrated and the conditions for minimal realization are also discussed.

• 한국자동차공학회논문집
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• 제5권5호
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• pp.51-66
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• 1997

A heat transfer model of the intake valve in a spark ignition engine is presented, which is calibrated with a number of the valve temperature profiles measured during engine warm-up for the gaseous fuel(propane). The valve is divided into four identical elements for which the assumption of lumped thermal mass is applied. The calibration is made so that the difference between the measued and simulated valve temperatures becomes minimal. Then the model is applied to the cases of the liquid fuel(indolene) to estimate the amount of the liquid fuel vaporized from the intake valve by assuming that fuel evaporation accounts for the deficit of the heat balance budget. The results of the model show quantitative contribution of each heat transfer source to the heat balance. The behavior of the calculated mass fraction of the fuel vaporized from the intake valve explains how the liquid fuel evaporate during engine warm-up. The mass fraction at warmed-up condition is closely related with the fraction directly targeted on the valve back by the fuel spray geometry.