• Title/Summary/Keyword: migration model

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WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation

  • Hu, JiSheng;Pi, ShangJing;Xiong, MingRui;Liu, ZhongYing;Huang, Xia;An, Ran;Zhang, TongCun;Yuan, BaiYin
    • Molecules and Cells
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    • v.43 no.8
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    • pp.749-762
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    • 2020
  • The migration, dedifferentiation, and proliferation of vascular smooth muscle cells (VSMCs) are responsible for intimal hyperplasia, but the mechanism of this process has not been elucidated. WD repeat domain 1 (WDR1) promotes actin-depolymerizing factor (ADF)/cofilin-mediated depolymerization of actin filaments (F-actin). The role of WDR1 in neointima formation and progression is still unknown. A model of intimal thickening was constructed by ligating the left common carotid artery in Wdr1 deletion mice, and H&E staining showed that Wdr1 deficiency significantly inhibits neointima formation. We also report that STAT3 promotes the proliferation and migration of VSMCs by directly promoting WDR1 transcription. Mechanistically, we clarified that WDR1 promotes the proliferation and migration of VSMCs and neointima formation is regulated by the activation of the JAK2/STAT3/WDR1 axis.

A Political Economic Analysis of Korean Reunification, Migration and Income Redistribution (남북통일과 이주 및 재분배정책에 대한 정치경제학 분석)

  • Moon, Weh-Sol
    • Economic Analysis
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    • v.26 no.1
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    • pp.34-83
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    • 2020
  • This paper examines two different reunification regimes and investigates the decision making problems on tax and income transfers in a political economy model. The first reunification regime is the South-Driven regime under which the majority of South Korea choose the tax rate, the amount of transfers and the size of migration. The second is the North-Participation regime under which there is no limit on migration and the majority of Unified Korea choose the tax rate and the amount of transfers. In both regimes, Northern residents' migration decisions are endogenous and those who decide not to migrate to the Southern region have an alternative to declare fiscal independence of income redistribution taking place within the North independently. This paper shows that there is no income redistribution in a politico-economic equilibrium under the South-Driven regime. Given that, those remaining in the Northern region decide to declare fiscal independence. On the other hand, the North-Participation regime delivers an equilibrium supporting income redistribution and no fiscal independence.

A Predictive Virtual Machine Placement in Decentralized Cloud using Blockchain

  • Suresh B.Rathod
    • International Journal of Computer Science & Network Security
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    • v.24 no.4
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    • pp.60-66
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    • 2024
  • Host's data during transmission. Data tempering results in loss of host's sensitive information, which includes number of VM, storage availability, and other information. In the distributed cloud environment, each server (computing server (CS)) configured with Local Resource Monitors (LRMs) which runs independently and performs Virtual Machine (VM) migrations to nearby servers. Approaches like predictive VM migration [21] [22] by each server considering nearby server's CPU usage, roatative decision making capacity [21] among the servers in distributed cloud environment has been proposed. This approaches usage underlying server's computing power for predicting own server's future resource utilization and nearby server's resource usage computation. It results in running VM and its running application to remain in waiting state for computing power. In order to reduce this, a decentralized decision making hybrid model for VM migration need to be proposed where servers in decentralized cloud receives, future resource usage by analytical computing system and takes decision for migrating VM to its neighbor servers. Host's in the decentralized cloud shares, their detail with peer servers after fixed interval, this results in chance to tempering messages that would be exchanged in between HC and CH. At the same time, it reduces chance of over utilization of peer servers, caused due to compromised host. This paper discusses, an roatative decisive (RD) approach for VM migration among peer computing servers (CS) in decentralized cloud environment, preserving confidentiality and integrity of the host's data. Experimental result shows that, the proposed predictive VM migration approach reduces extra VM migration caused due over utilization of identified servers and reduces number of active servers in greater extent, and ensures confidentiality and integrity of peer host's data.

Prediction for the Spatial Distribution of Occupational Employment by Applying Markov Chain Model (마르코프 체인 모형을 이용한 직종별 취업자의 공간적 분포 변화 예측)

  • Park, So Hyun;Lee, Keumsook
    • Journal of the Korean Geographical Society
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    • v.51 no.4
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    • pp.525-539
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    • 2016
  • This study attempts to predict the changes in the spatial distribution of occupational employment in Korea by applying Markov Chain Model. For the purpose we analyze the job-related migration pattern and estimate the transition probability with the last six years job-related migration data. By applying the Chapman-Kolmogorov equation based on the transition probability, we predict the changes in the spatial distribution of occupational employment for the next ten years. The result reveals that the employment of professional jobs is predicted to increase at every city and region except Seoul, while the employment of elementary labor jobs is predicted to increase slightly in Seoul. In particular, Gangwon-do and Chuncheongdo are predicted to increase in the employment of all occupational jobs.

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Empirical Analysis on Potential Labor Migration between Countries Implemented by Harris-Todaro Model: Result from Korea, China, and Japan (Harris-Todaro 모형에 의한 국가간 잠재적 노동인구 이동에 관한 실증분석: 한-중-일 3국을 중심으로)

  • Rhee, Hyun-Jae
    • The Journal of the Korea Contents Association
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    • v.15 no.6
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    • pp.421-431
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    • 2015
  • This study aims to examine potential labor migration between Korea, China, and Japan by Harris-Todaro model which is enhanced in the presence of expected income differential. The results suggest that Korean labor forces are bi-directionally migrated to China and Japan, simultaneously, and Chinese labor forces have been switched from inflow to outflow. On the other hand, Japanese labor markets are characterized by inflow from Korea, and outflow to China. The nature of labor markets in Northeast Asia have been largely transformed such that inflow of immigrants is gradually intimidated. This is mainly due to the fact that the labor markets are gradually homogenized in this region. To this end, it could be tentatively concluded that the labor markets in Northeast Asia seem to be operated by substitutionary rather than complementary natures.

Oviposition Time of Overwintered Females and Migration of Crawlers of Pseudaulacaspis prunicola (Homoptera: Diaspididae) on Cherry Trees in Jeju Island (제주도 벚나무에 발생하는 벚나무깍지벌레 월동성충의 산란시기 및 부화약충 이동시기)

  • Kim, Dong-Soon
    • Korean journal of applied entomology
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    • v.44 no.3 s.140
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    • pp.231-235
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    • 2005
  • This study was conducted to obtain the optimal spray time for Pseudaulacaspis prunicota (Maskell) (Homoptera: Diaspididae) in early seaon in Jeju. Oviposition time of overwintered females and activity of hatched nymphs of P. prunicola were monitored, and the phenology data were compared with the outputs estimated by a degree-days model of P. pentagona (Targioni-Tozzetti)). Overwintered females of P. prunicola began to lay eggs from mid to late April, and the eggs started to hatch from early May followed by the active migration of the hatched nymphs during mid May. The phenological events of P. prunicola in early season were likely comparable with those of P. pentagona reported in southern Korea and in central Japan. A degree-day model, which predicts the proportion of >50% hatched egg batches of P. pentagona (y=1[exp(-(-a+bx))]; y, proportion; x, degree-days based on $10.5^{\circ}C$ from 1 January; a=-18.80 and b=0.073), accurately described the migration time of P. prunicola hatched nymphs. Thus, it is considered that the degree-day model can be used for predicting the optimal spray time for P. prunicola in early season.

Interrelationship Between Regional Population Migration, Crop Area, and Foreign Workers (지역 간 인구이동, 경지면적, 외국인 근로자의 관계 분석)

  • Seojin Cho;Heeyeun Yoon
    • Journal of the Korean Regional Science Association
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    • v.40 no.2
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    • pp.21-38
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    • 2024
  • Understanding the interrelationship between regional population dynamics and cultivated land is crucial for promoting regional economic vitality and enhancing food security. While prior research often addressed population migration and changes in crop area separately, this study employs a Panel Vector Auto Regression Model to examine the dynamic interaction between regional population shifts, changes in crop area, and the influx of foreign workers in agriculture. The results reveal a reciprocal relationship between population influx and crop area, indicating a negative impact on each other. Moreover, the analysis demonstrates that an expansion in crop area, particularly in field cultivation, significantly correlates with an increase in foreign workers. These findings underscore the mutual influence of labor shortages and diminished land availability in agriculture, with the influx of foreign workers potentially offering a positive impact on addressing structural challenges in rural areas.

Computational analysis of cancer angiogenesis using two dimensional model (2차원 모델을 이용한 암의 혈관생성에 대한 수치적 연구)

  • Shim Eun Bo;Ko Hyung Jong;Deisboeck Thomas
    • Proceedings of the KSME Conference
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    • 2002.08a
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    • pp.709-710
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    • 2002
  • Cancer angiogenesis is simulated using a two dimensional model. Governing equation of angiogenesis is a TAE (Tumor angiogenesis factor) conservation equation in time and space. A stochastic process model is utilized to simulate vessel formation, proliferation, and migration to a cancer pellet. Numerical results are presented especially in case of growing cancer.

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Effects of Climate-Changes on Patterns of Seasonal Changes in Bird Population in Rice Fields using a Prey-Predator Model (포식자-피식자 모델을 이용하여 기후변화가 논습지를 이용하는 조류 개체군 동태에 미치는 영향 예측)

  • Lee, Who-Seung
    • Korean Journal of Environmental Agriculture
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    • v.32 no.4
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    • pp.294-303
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    • 2013
  • BACKGROUND: It is well known that rice-fields can provide excellent foraging places for birds including seasonal migrants, wintering, and breeding and hence the high biodiversity of rice-fields may be expected. However, how environmental change including climate-changes on life-history and population dynamics in birds on rice-fields has not been fully understood. In order to investigate how climate-change affects population migratory patterns and migration timing, I modeled a population dynamics of birds in rice-fields over a whole year. METHODS AND RESULTS: I applied the Lotka-Volterra equation to model the population dynamics of birds that have been foraging/visiting rice-fields in Korea. The simple model involves the number of interspecific individuals and temperature, and the model parameters are periodic in time as the biological activities related to the migration, wintering and reproduction are seasonal. As results, firstly there was a positive relationship between the variation of seasonal population sizes and temperature change. Secondly, the reduced lengths of season were negatively related to the population size. Overall, the effects of the difference of lengths of season on seasonal population dynamics were higher than the effects of seasonal temperature change. CONCLUSION(S): Climate change can alter population dynamics of birds in rice-fields and hence the variation may affect the fitness, such as reproduction, survival and migration. The unstable balances of population dynamics in birds using paddy rice field as affected by climate change can reduce the population growth and species diversity in rice fields. The results suggest that the agricultural production is partly affected by the unstable balance of population in birds using rice-fields.

Study of the Calendar Aging of Lithium-Ion Batteries Using SEI Growth Models (SEI 성장 모델을 이용한 리튬 이온 배터리의 캘린더 노화 연구)

  • Dong Hyup Jeon;Byungman Chae;Sangwoo Lee
    • Applied Chemistry for Engineering
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    • v.35 no.1
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    • pp.48-53
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    • 2024
  • We predicted the calendar aging and long-term lifetime of lithium-ion batteries using an electrochemical-based SEI growth model. Numerical simulation was carried out employing the four different long-term SEI growth models (i.e., solvent diffusion limited model, electron migration limited model, Li-interstitial diffusion limited model, reaction limited model), and we calculated the capacity fade and loss of lithium inventory during calendar aging. The result showed that the electron migration limited model and Li-interstitial diffusion limited model showed lower capacity fade, while the solvent diffusion limited model and reaction limited model reached 80% of capacity fade within 10 years. During calendar aging, the lower storage temperature showed less capacity fade due to the hindrance of SEI growth rate. During cycling, the higher C-rate showed a shorter life cycle; however, the differences were not significant.