• Animal Bioscience
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• 제36권10호
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• pp.1488-1498
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• 2023

Objective: α_S1-Casein is more closely associated with milk allergic reaction than other milk protein components. microRNA (miRNA) is a class of small non-coding RNAs that modulate multiple biological progresses by the target gene. However, the post-transcriptional regulation of α_S1-casein expression by miRNA in ruminants remains unclear. This study aims to explore the regulatory roles of miR-380-3p on α_S1-casein synthesis in goat mammary epithelial cells (GMEC). Methods: α_S1-Casein gene and miR-380-3p expression was measured in dairy goat mammary gland by quantitative real-time polymerase chain reaction (qRT-PCR). miR-380-3p overexpression and knockdown were performed by miR-380-3p mimic or inhibitor in GMEC. The effect of miR-380-3p on α_S1-casein synthesis was detected by qRT-PCR, western blot, luciferase and chromatin immunoprecipitation assays in GMEC. Results: Compared with middle-lactation period, α_S1-casein gene expression is increased, while miR-380-3p expression is decreased during peak-lactation of dairy goats. miR-380-3p reduces α_S1-casein abundance by targeting the 3'-untranslated region (3'UTR) of α_S1-casein mRNA in GMEC. miR-380-3p enhances β-casein expression and signal transducer and activator of transcription 5a (STAT5a) activity. Moreover, miR-380-3p promotes β-casein abundance through target gene α_S1-casein, and activates β-casein transcription by enhancing the binding of STAT5 to β-casein gene promoter region. Conclusion: miR-380-3p decreases α_S1-casein expression and increases β-casein expression by targeting α_S1-casein in GMEC, which supplies a novel strategy for reducing milk allergic potential and building up milk quality in ruminants.

• Education of Primary School Mathematics
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• 제26권3호
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• pp.199-217
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• 2023

Affective characteristics have been consistently emphasized in mathematics education, but students' confidence or interest in mathematics has not changed significantly. This study analyzes the factors affecting the affective characteristics according to students' academic achievements, which have not been studied so far. The study was surveyed 593 students in the 5th and 6th grades, divided into school mathematics education and social-environmental factors. As a result of the study, students cited 'mathematics class at school' as the factor that had the most influence on their affective characteristics, regardless of academic achievement. Excluding 'mathematics classes at school', upper level students said that 'private education' and 'college entrance exams and jobs', had the most influence on their affective characteristics. Middle level students said that 'assessment at school' and 'private education' had the most influence on their affective characteristics. Lower-level students said that 'school evaluation' and 'mathematics textbook' had the most influence on the affective characteristics. In particular, as the academic achievement level decreased, students' participation in classes decreased rapidly. Most students said that the mathematics content they were learning was too difficult for that reason. Considering these research results, it would be effective to apply methods according to students' academic achievement to some extent in order to improve affective characteristics.

• Korean Journal of Culture and Social Issue
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• 제22권1호
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• pp.119-135
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• 2016

We tried to develop the school violence prevention program which focuses on the bystanders. In the context of school violence, most students are bystanders. They can either reinforce the violence or stop the violence. We hypothesized that the students who know their own temperament dimensions such as novelty seeking, harm avoidance, and reward dependence (Cloninger, 1994) will show more tendencies to defend victims from school violence when they learned the methods to prevent school violence in accordance to their temperament dimensions. 351 Korean middle school students participated the 4 sessions of school violence prevention program. The students completed the questionnaires to identify their own behavior in school violence situations. In the experimental group(temperament group), students learned the methods to help the victims that suits with their own temperaments. Whereas, the comparison group just attend the class regardless of their temperaments. Both groups showed significant increase in the trend of defending the victims. However, the temperament group showed more tendency to protect/defend the victims than the comparison group when they faced with school violence. These results show that students can learn the methods of defending victims from school violence more easily by knowing their own temperament dimensions, and can be the prepared and the effective defenders.

• Journal of Digital Convergence
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• 제22권2호
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• pp.21-28
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• 2024

This study analyzed the current status of care policies and senior citizen issues in Korea, which has entered a super-aging society, and attempted to suggest improvement measures for desirable convergence policies. The problems of the elderly in Korea have emerged as health problems, poverty problems, loss of roles, and care problems due to changes in the concept of family, values, and socioeconomic structure. In addition, poor seniors need jobs and employment policies, and healthy middle-class seniors need policy development to enable leisure activities and volunteer activities. In particular, it is necessary to establish policies to enable people to spend the rest of their lives in elderly care facilities and elderly care hospitals through community care policies. The super-aging society accounts for more than 20% of the total population among those aged 65 or older, and according to the National Statistical Office, it is expected to become a super-aging society by 2025. Elderly welfare policies must provide various programs and the needs and services of elderly care, and in the future, a super-aging society will need to secure a lot of financial resources and maintain a productive population to cover the financial resources. In other words, the human life cycle is from birth to death, and when the ratio of natural deaths of the elderly and infants born is appropriate, the society and the country can be seen as stable, vibrant, and healthy societies.

• Journal of The Korean Association For Science Education
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• 제29권1호
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• pp.116-136
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• 2009

Since there are differences in the content, structure and functions of interpersonal communication during the practice of school science classes, it needs to articulate the difference of the modality of pedagogical practice in order to understand science teaching in detail. These characteristics of science teaching can be investigated by further insightful analysis on language in the science classroom. In this study, classroom discourse language codes using Bernstein's code theory were analyzed in the case of a middle school science class on the unit of minerals. The discourse language code was identified by the value of classification, which revealed power relations to the contexts of discourse and participants of discourse. It was also identified by the value of framing, which showed hierarchical relation between teacher and students as discourse subjects, and discursive control on the initiative of discourse. The results addressed that six types of discourse language codes were constructed and that those language codes reflected diverse modalities of science teaching from student-centered instruction to teacher-centered instruction in relation to classroom discourse. The modality of science teaching according to the transition tendencies of discourse language code showed dynamic variations of 'controlled student-centeredness inducing teaching' - 'positional student-centeredness permissive teaching' - 'controlled students' participation permissive teaching' - 'controlled student-centeredness facilitative teaching' - 'student-centeredness enhancing teaching'. In addition, results released that discursively and hierarchically weak control of discourse is necessary for enhancing student-centeredness of science teaching. Moreover, teaching practice enhancing student-centeredness can be accomplished by the harmony of a teacher's perception of discourse language code and his/her orientation to constructivist teaching and student-centered teaching.

• Journal of The Korean Association For Science Education
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• 제26권3호
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• pp.367-375
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• 2006

This study investigated the effects of varying visuals in drawing and writing as methods to assist students in connecting and integrating multiple external representations provided in learning the particulate nature of matter. Seventh graders (N=233) at a coed middle school were assigned to control, static drawing (SO), dynamic drawing (DD), static writing (SW), and dynamic writing (DW) groups. The students were taught about "Boyle's Law" and "Charles's Law" for two class periods. Two-way ANCOVA results revealed that the scores of a conception test for the two drawing (SD, DD) groups and the two writing (SW, DW) groups were significantly higher than those for the control group. Within the writing groups, students of lower spatial visualization ability in the DW group scored significantly higher than those in the SW group. However, no significant differences were found in the scores of the conception test for the two drawing (SD, DD) groups regardless of students' visualization ability. Researchers also found that most students in both DD and DW groups had respectively positive perceptions of dynamic visuals in drawing or writing.

• Journal of The Korean Association For Science Education
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• 제26권2호
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• pp.191-199
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• 2006

This study investigated the influence of time to draw students' mental models and students' field dependence-independence on learning the particulate nature of matter with multiple representations. Seventh graders (N=295) at two middle schools were assigned to control, after-drawing, and before-drawing groups. The students learned "Boyle's Law" and "Charles's Law" for two class periods. Results revealed that the scores of a test on conceptual understanding for the two drawing groups were significantly higher than those for the control group. However, there was no significant interaction between the instruction and students' field dependence-independence in the scores of the test on conceptual understanding. In 'novelty' on a situational interest test, field independent students in the two drawing groups scored significantly higher than those in the control group. The scores for field independent students in each group were similar, while field dependent students in the before-drawing group scored lower than those in the control and after-drawing groups in 'attention demand' on the situational interest test. It was found that most students positively perceived after-drawing or before-drawing, but field independent students in the before-drawing group were more apprehensive about the activities than those in the after-drawing group.

• Journal of The Korean Association For Science Education
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• 제29권6호
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• pp.741-750
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• 2009

Modem science education was introduced to Korea in the enlightenment period. The science textbooks which were published at that time were important to modem science education in Korea. Therefore, the translators and publishers of science textbooks were the leader of the science education in the enlightenment period. Hyun Chae and his son as a translator were one of the leaders in science education at that time. Hyun Chae was born to a Middle class (中人)family and succeeded to pass the national examination for translators (譯科). He worked as a translator and author at the Ministry of Education (學部). Also, he was the associate teacher in a foreign school and the Hansung normal school (漢城師範學校). He published 26 books. One of them, Rikwa (理科) as the science textbook covering all the areas of science, physics, chemistry, biology and earth science. That presented the knowledge, which students should know by proper method, induced students' interest and included various experiments. Hyun Chae's activity in science education as the author and translator of science textbooks was an important role on the forming science education in the enlightenment period because it was caught short of science textbooks. The author, translator, and publisher of science textbooks was of great significance to make science popular, which was the new culture. Therefore, the role and activities in science education of Hyun Chae was a part of the history of science education, he knew a foreign language and was the leader in facilitating exchange with foreign countries.

• Journal of The Korean Association For Science Education
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• 제27권1호
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• pp.28-36
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• 2007

This study investigated the influences of small group discussion and students' visual learning style in learning chemical concepts with drawing and writing as methods to assist students in connecting and integrating multiple external representations. Seventh graders (N=449) at a coed middle school were assigned to individual drawing (ID), pair drawing (PD), individual writing (IW), and pair writing (PW) groups. All students learned "Boyle's Law" and "Charles's Law" for two class periods. Analyses of the results revealed that the students in the PD group, regardless of students' visual learning style, scored significantly higher than those in the ID group in a conception test. The scores of the students with strong visual learning preference in the PW group were significantly higher than those in the IW group in the conception test, while the scores of the students with weak visual learning preference were not significantly different between the two groups. Although the conception test scores of the PD group were higher than those of the PW group, the difference was relatively small. It was found that most students in both PD and PW groups perceived pair drawing and pair writing positively upon cognitive and motivational aspects.

• Journal of The Korean Association For Science Education
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• 제28권2호
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• pp.120-129
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• 2008

In this study, 17 formative assessments using cartoon were developed for studying 'genetics and evolution' chapter in textbook of third grade of junior high school. And those were applied to 73 students in experimental group and 78 students in control group. We investigated if there was positive effect on students' perception, attitude about assessment and scholastic achievement. As a result, we could find the formative assessments using cartoon were effective to change students' negative perception and attitude to positive one. Especially, those were effective to make students to understand usefulness of assessment (p<.05), and to decrease a feeling of uneasiness about assessment (p<.01). Also, we could find the developed formative assessments using cartoon had more positive effect on raising scholastic achievement than formative assessment using descriptive passage (p<.05). It was considered that this was because the abstract concepts of 'genetics and evolution' chapter were described in pictures, so contexts of textbook and assessment questions became easier to understand. So, we could conclude that formative assessment using cartoon contributed to increase students' understanding of contexts of textbook and to increase their interests about study. And if this assessment method is applied to class actively, students' feeling of uneasiness about assessment can be easily overcome and it can also give them positive perception about assessment.