• 대한전기학회논문지:전기물성ㆍ응용부문C
• /
• 제55권2호
• /
• pp.88-92
• /
• 2006

We present a microfluidic system with microvalves and a micropump that are easily integrated on the same substrate using the same fabrication process. The fabricated microfluidic system is suitable for use as a disposable device and its characteristics are optimized for use as a micro chemical analysis system (micro-TAS) and lab-on-a-chip. The system is realized by means of a polydimethylsiloxane (PDMS)-glass chip and an indium tin oxide (ITO) heater. We demonstrate the integration of the micropump and microvalves using a new thermopneumatic-actuated PDMS-based microfluidic system. A maximum pumping rate of about 730 nl/min is observed at. a duty ratio of 1 $\%$ and a frequency of 2 Hz with a fixed power of 500 mW. The measured power at flow cut-off is 500 mW for the microvalve whose channel width, depth and membrane thickness were 400 $\mu$m, 110 $\mu$m, and 320 $\mu$m, respectively.

• Applied Science and Convergence Technology
• /
• 제24권5호
• /
• pp.196-202
• /
• 2015

Human blood consists of 55% of plasma and 45% of blood cells such as white blood cell (WBC) and red blood cell (RBC). In plasma, there are many kinds of promising biomarkers, which can be used for the diagnosis of various diseases and biological analysis. For diagnostic tools such as a lab-on-a-chip (LOC), blood plasma separation is a fundamental step for accomplishing a high performance in the detection of a disease. Highly efficient separators can increase the sensitivity and selectivity of biosensors and reduce diagnostic time. In order to achieve a higher yield in blood plasma separation, we propose a novel fluid wing structure that is optimized by COMSOL simulations by varying the fluidic channel width and the angle of the bifurcation. The fluid wing structure is inspired by the inertial particle separator system in helicopters where sand particles are prevented from following the air flow to an engine. The structure is ameliorated in order to satisfy biological and fluidic requirements at the micro scale to achieve high plasma yield and separation efficiency. In this study, we fabricated the fluid wing structure for the efficient microfluidic blood plasma separation. The high plasma yield of 67% is achieved with a channel width of $20{\mu}m$ in the fabricated fluidic chip and the result was not affected by the angle of the bifurcation.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2003년도 추계학술대회 논문집 전기물성,응용부문
• /
• pp.286-289
• /
• 2003

We investigated the influence of the properties of substrate material on the separation efficiency in microchip electrophoresis. We fabricated the various microchips and studied separation efficiency in microchannels composed of a single material such as quartz, glass, polydimethylsiloxane (PDMS), and polymethylmetha crylate (PMMA), as well as hybrid micro channels composed of different materials. New fabrication process for glass chip was suggested and some treatment is added to improve fabrication process in other chip. Separation efficiency was compared by measuring migration times and bandwidths of EOF and analytes in each microchip. The efficiency is the function of migration time, which is affected by the electroosmotic flow (EOF), and bandwidth of an analyte. EOF is highly dependent upon the characteristics of a microchannel wall surface. Migration time was more reproducible in silica chips than that of PDMS chip and more band broadening was observed in the microchip composed of hybrid material due to non-uniformity of surface charge density at the walls of the channel.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2007년도 춘계학술대회B
• /
• pp.2666-2671
• /
• 2007

This work presents microchannel heat sink shape optimization procedure using Kriging method. Design variables relating to microchannel width, depth and fin width are selected, and thermal resistance has been taken as objective function. Design points are selected through a three-level fractional factorial design of sampling method. Navier-Stokes and energy equations for laminar flow and conjugate heat transfer are solved at these design points using a finite volume solver. Solutions are carefully validated with experimental results. Using the numerically evaluated objective function, a surrogate model (Kriging) is constructed and optimum point is searched by sequential quadratic programming. The process of shape optimization greatly improves the thermal performance of microchannel heat sink under constant pumping power.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2001년도 춘계학술대회논문집E
• /
• pp.430-435
• /
• 2001

This paper introduces a pressure correction method for microflow computation. Conventional CFD methods with no slip boundary condition fail to predict the rarefaction effect of the wall when simulating gas microflows in the slip-flow regime. Pressure correction method with an appropriate slip boundary condition is an efficient tool in analyzing microscale flows. The present unstructured SIMPLE algorithm adopts both the classical Maxwell boundary condition and Langmuir boundary condition proposed by Myong. The simulation results of microchannel flows show that the proposed method has an effective predictive capability for microscale flows.

• 대한기계학회논문집B
• /
• 제31권9호
• /
• pp.733-740
• /
• 2007

Microchannel heat sink shape optimization is performed using Kriging method. Design variables relating to microchannel width, depth and fin width are selected, and thermal resistance has been taken as objective function. Design points are selected through a three-level fractional factorial design of sampling method. Navier-Stokes and energy equations for laminar flow and conjugate heat transfer are solved at these design points using a finite volume solver. Solutions are carefully validated with experimental results. Using the numerically evaluated objective function, a surrogate model (Kriging) is constructed and optimum point is searched by sequential quadratic programming. The process of shape optimization greatly improves the thermal performance of microchannel heat sink under constant pumping power.

• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 2003년도 The Fifth Asian Computational Fluid Dynamics Conference
• /
• pp.118-120
• /
• 2003

The behavior of viscous fingerings caused by an external force is investigated by using a two­phase lattice Boltzmann method. The effects of the modified capillary number, the viscosity contrast, and the modified Darcy-Rayleigh number on the instability of interfaces are found. The calculated wave numbers are in good agreement with the theoretical ones in the range of wave numbers smaller than 10, but the calculated ones tend to become smaller than the theoretical ones in higher wave numbers.

• 한국가시화정보학회:학술대회논문집
• /
• 한국가시화정보학회 2007년도 추계학술대회
• /
• pp.66-70
• /
• 2007

현재 많은 연구들이 작은 크기에 여러 공정을 집적시킬 수 있는 장점을 가진 마이크로 장치의 개발과 활용에 집중되고 었다. 마이크로 장치에서 가장 중요한 것은 미세 유동의 효율적인 제어이다. 본 연구에서는 마이크로 장치에 직접 적용 가능한 표면 개질 된 마이크로 채널의 유동에 대하여 고려하였다. 표면 개질(surface treatment)은 물리적, 화학적인 작용을 통해서 채널 내부 표면의 습윤성을 변화시켜 유동을 제어하는 방법이다. 친수성(glass)을 가지는 마이크로 채널 내부의 일부를 소수성(teflon)으로 개질 후, 고속카메라를 이용하여 채널 내부를 흐르는 유체의 유동 경계면 변화를 분석하였다. 또한 유동 해석을 위한 상용 코드(CFD-ACE)를 이용하여 유동에 대한 수치 해석을 진행하여 가시화된 실험 결과와 비교 분석하였다. 실험 결과와 수치 해석 결과를 통해, 친수성과 소수성 표면 배열에 따른 일시적인 유동 변화를 관찰하였다. 본 연구 결과를 통해 마이크로 채널 유동의 최적화 상태를 찾을 수 있으며, 보다 용이한 미세 유동 제어가 가능하다.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2002년도 학술대회지
• /
• pp.483-486
• /
• 2002

Injection of microbubbles and/or polymer solution has been known to be a promising method for the reduction of frictional drag of water-borne vehicles. Naval Architects have been interested in friction drag reduction technology, since the friction drag of a commercial ship can be over $70{\%}$ of total resistance. The reduction of friction drag is also important for autonomous underwater vehicles and naval submarines to improve their durability and survivability In this study two sets of experiments were carried out for the friction drag reduction of 2-D channel wall and flat plate in the circulating water channels in Chungnam National University. Preliminary results from the experiments are presented and discussed.

• 대한전기학회논문지:전기물성ㆍ응용부문C
• /
• 제51권9호
• /
• pp.449-454
• /
• 2002

A rectangular straight microchannel, integrated with the resistance temperature detectors(RTDs) for temperature sensing and a micro-heater for generating the Temperature gradient along the channel, was fabricated. Its dimension is 57${\mu}{\textrm}{m}$(H)$\times$200${\mu}{\textrm}{m}$(W)$\times$48,050${\mu}{\textrm}{m}$(L), and RTDs were placed at the inner-channel wall. Si wafer was used as a substrate. For the fabrication of RTDs, 5300$\AA$ thick Pt/Ti layer was sputtered on a Pyrex glass wafer. Finally, the glass wafer was bonded with Si wafer by anodic bonding, so that the RTDs are located inside the microchannel. Temperature coefficient of resistance(TCR) values of the fabricated Pt-RTDs were 2800~2950ppm$^{\circ}C$ and the variation of TCR value In the range of O~10$0^{\circ}C$ was less than 0.3％. Therefore, it was proved that the fabricated Pt-RTDs without annealing were excellent as temperature sensors. The temperature distribution in the microchannel was investigated as a function of mass flow rate and heating power. The temperature increase rate diminished with decreasing the applied power and increasing the mass flow rate. It was confirmed from the comparison with the simulation results that the temperature measured inside the microchannel is more accurate than measuring the temperature measured at the outer wall. The proposed temperature sensing method and microchannel are expected to be useful in microfluidics researches.