• Title/Summary/Keyword: micro analysis

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An Efficient Functional Analysis Method for Micro-array Data Using Gene Ontology

  • Hong, Dong-Wan;Lee, Jong-Keun;Park, Sung-Soo;Hong, Sang-Kyoon;Yoon, Jee-Hee
    • Journal of Information Processing Systems
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    • 제3권1호
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    • pp.38-42
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    • 2007
  • Microarray data includes tens of thousands of gene expressions simultaneously, so it can be effectively used in identifying the phenotypes of diseases. However, the retrieval of functional information from a large corpus of gene expression data is still a time-consuming task. In this paper, we propose an efficient method for identifying functional categories of differentially expressed genes from a micro-array experiment by using Gene Ontology (GO). Our method is as follows: (1) The expression data set is first filtered to include only genes with mean expression values that differ by at least 3-fold between the two groups. (2) The genes are then ranked based on the t-statistics. The 100 most highly ranked genes are selected as informative genes. (3) The t-value of each informative gene is imposed as a score on the associated GO terms. High-scoring GO terms are then listed with their associated genes and represent the functional category information of the micro-array experiment. A system called HMDA (Hallym Micro-array Data analysis) is implemented on publicly available micro-array data sets and validated. Our results were also compared with the original analysis.

몬테카를로 시뮬레이션에 의한 미소 비커스 경도의 Weibull 통계 해석 (Weibull Statistical Analysis of Micro-Vickers Hardness using Monte-Carlo Simulation)

  • 김선진;공유식;이상열
    • 대한기계학회논문집A
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    • 제33권4호
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    • pp.346-352
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    • 2009
  • In the present study, the Weibull statistical analysis using the Monte-Carlo simulation has been performed to investigate the micro-Vickers hardness measurement reliability considering the variability. Experimental indentation test were performed with a micro-Vickers hardness tester for as-received and quenching and tempering specimens in SCM440 steels. The distribution of micro-Vickers hardness is found to be 2-parameter Weibull distribution function. The mean values and coefficients of variation (COV) for both data set are compared with results based on Weibull statistical analysis. Finally, Monte-Carlo simulation was performed in order to evaluate the effect of sample size on the micro-Vickers hardness measurement reliability. For the parent distribution with shape parameter 30.0 and scale parameter 200.0 (COV=0.040), the number of sample data required to obtain the true Weibull parameters was founded by 20. For the parent distribution with shape parameter 10.0 and scale parameter 200.0 (COV=0.1240), the number of sample data required to obtain the true Weibull parameters was founded by 30.

마이크로 웨이브 탐색기의 김발 구조물 진동해석(II) : 유한요소해석 (Vibration Analysis for Gimbal Structure of a Micro Wave Seeker(II) : Finite Element Analysis)

  • 장영배;전홍걸;이석규;윤재윤;박영필
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2000년도 춘계학술대회논문집
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    • pp.514-518
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    • 2000
  • Micro wave seeker consists of a gimbal structure, a antenna and many RF parts. And Missile's propelling powers excite a gimbal structure, a antenna and many RF parts. Therefore, We must inquire into external forces to act on a micro wave seeker before everything. We must inquire into design parameters and then estimate dynamic characteristics of a gimbal structure with a finite element model to reflect part's characteristics for design for a gimbal structure in consideration of vibration features. In this paper, a gimbal structure of a micro wave seeker is modeled in finite element method and then updated by using the experimental modal data. Before we make a finite element model of a gimbal structure of a micro wave seeker, we make a finite element model of a sub-structure and compare with the experimental modal data.

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미세형상 가공을 위한 Micro Slot 가공에서의 공구변형에 의한 가공오차 보상 (Machining Error Compensation for Tool Deflection in Micro Slot-Cutting Processes for Fabrication of Micro Shapes)

  • 손종인;윤길상;서태일
    • 한국공작기계학회논문집
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    • 제17권2호
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    • pp.121-127
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    • 2008
  • Micro end-milling has been becoming an important machining process to manufacture a number of small products such as micro-devices, bio-chips, micro-patterns and so on. Despite the importance of micro end-milling, many related researches have given grand efforts to micro end-milling phenomenon, for example, micro end-milling mechanism, cutting force modeling and machinability. This paper strongly concerned actual problem, micro tool deflection, which causes excessive machining errors on the workpiece. To solve this problem, machining error prediction method was proposed through a series of test micro cutting and analysis of their SEM images. An iterative algorithm was applied in order to obtain corrected tool path which allows reducing machining errors in spite of tool deflection. Experiments are carried out to validate the proposed approaches. In result, remarkable error reduction could be obtained.

Thermo-elastic analysis of rotating functionally graded micro-discs incorporating surface and nonlocal effects

  • Ebrahimi, Farzad;Heidar, Ebrahim
    • Advances in aircraft and spacecraft science
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    • 제5권3호
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    • pp.295-318
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    • 2018
  • This research studies thermo-elastic behavior of rotating micro discs that are employed in various micro devices such as micro gas turbines. It is assumed that material is functionally graded with a variable profile thickness, density, shear modulus and thermal expansion in terms of radius of micro disc and as a power law function. Boundary condition is considered fixed-free with uniform thermal loading and elastic field is symmetric. Using incompressible material's constitutive equation, we extract governing differential equation of four orders; to solution this equation, we utilize general differential quadrature (GDQ) method and the results are schematically pictured. The obtained result in a particular case is compared with another work and coincidence of results is shown. We will find out that surface effect tends to split micro disc's area to compressive and tensile while nonlocal parameter tries to converge different behaviors with each other; this convergence feature make FGIMs capable to resist in high temperature and so in terms of thermo-elastic behavior we can suggest, using FGIMs in micro devices such as micro turbines (under glass transition temperature).

좌굴과 상변화를 이용한 Micro Actuator의 개발 및 해석 (Development and Analysis for Micro Actuator Using Buckling Membrane and Phase Change)

  • 송귀은;김정식;김광호;이윤표
    • 대한기계학회논문집B
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    • 제28권6호
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    • pp.638-645
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    • 2004
  • A new micro actuation concept is introduced and studied in this paper. This idea is based on the thermo-pneumatic actuation principle. In order to improve the performance of a conventional thermo-pneumatic actuator, the idea of bistable buckling is added. By using a membrane which has the bistable buckling characteristics, the working pressure difference can be increased and as a result the work output can be increased. The analysis model for each phenomenon, bistable buckling and phase change, are suggested and the each model is verified with experimental data. From the comparison of the theoretical prediction with the experimental results, it can be concluded that these models are useful for such micro actuator analysis.

PSCAD/EMTDC를 이용한 DC Micro-grid의 동작 분석 (Operational Analysis of DC Micro-grid using PSCAD/EMTDC Software)

  • 이지헌;권기현;한병문
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2009년도 제40회 하계학술대회
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    • pp.446_447
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    • 2009
  • This paper describes operational analysis results of the DC micro-grid using detailed model of distributed generation. Detailed model of wind power generation, photo-voltaic generation, fuel-cell generation was implemented with the user-defined model of PSCAD/EMTDC software that is coded with C-language. Various simulation results confirm that the DC micro-grid can operate without any problem in both the interconnected mode and the islanded mode. The operation analysis result confirms that the DC micro-grid make it feasible to provide power to the load stably.

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소상공인의 경영성과 결정요인 (A Study on Determinants of Micro-enterprise Performance)

  • 오상영
    • 한국산학기술학회논문지
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    • 제13권12호
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    • pp.5759-5763
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    • 2012
  • 정부의 소상공인 정책자금, 교육, 컨설팅 지원에 대한 효과 분석을 통하여 정부지원정책이 경영성과에 미치는 영향과 소상공인특성이 경영성과에 미치는 영향을 고려한 구조모형 분석을 실시하였다. 연구 결과 소상공인특성 및 정부지원정책은 경영성과에 유의한 영향을 미치는 것으로 나타났으며 구조모형에서 유의한 독립변수는 고객진입용이성, 사업홍보용이성, 상품이동용이성, 고객확보용이성과 자금지원의 효과성, 교육지원규모, 교육지원의 효과성, 컨설팅지원규모의 만족도 등으로 나타났다.

주성분분석과 신경회로망의 융합을 통한 실리콘 웨이퍼의 마이크로 크랙 분류에 관한 연구 (A Study on Classification of Micro-Cracks in Silicon Wafer Through the Fusion of Principal Component Analysis and Neural Network)

  • 서형준;김경범
    • 한국정밀공학회지
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    • 제32권5호
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    • pp.463-470
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    • 2015
  • Solar cell is typical representative of renewable green energy. Silicon wafer contributes about 66 percent to its cost structure. In its manufacturing, micro-cracks are often occurred due to manufacturing process such as wire sawing, grinding and cleaning. Their detection and classification are important to process feedback information. In this paper, a classification method of micro-cracks is proposed, based on the fusion of principal component analysis(PCA) and neural network. The proposed method shows that it gives higher results than single application of two methods, in terms of shape and size classification of micro-cracks.

가스 용해를 고려한 금형내압제어 사출성형공정의 마이크로패턴 충전 해석 (Numerical Analysis of Micro-pattern Filling with Gas Dissolution by Injection Molding Process)

  • 박성호;유형민;이우일
    • 한국기계가공학회지
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    • 제13권4호
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    • pp.21-27
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    • 2014
  • The injection molding process has several advantages enabling it to produce large quantities of molded plastic products using a repetitive process. In recent years, it has been necessary to develop an injection molding process with micro/nano-sized patterns for application to the semiconductor industry and to the bio/nano manufacturing industry. In this study, we apply gas pressure to the inside of a mold and consider the gas dissolution phenomenon for a resin filling into a micro pattern with a line structure. Using numerical analysis, we calculate the filling ratio with respect to time for various internal gas pressures and various aspect ratios of the micro-patterns.