• Proceedings of the Korean Information Science Society Conference
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• 2006.06a
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• pp.13-15
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• 2006

microRNA는 유전자의 전사 후 과정에서 negative regulation을 담당하는 small noncoding RNA의 한 증류이다. 최근까지 330여개의 인간 microRNA가 발견되었지만 그들의 기능이 밝혀진 것은 소수에 불과하다. microRNA의 기능은 3'UTR에 불완전 상보결합을 통해 negative regulation을 받게 되는 유전자의 기능으로부터 유추되는 것이 일반적이다. 특별히 유전체상에 군집화 된 microRNA들은 하나의 전사체로부터 발현되는 것으로 판단되며, 같은 또는 관련된 기능을 하거나 같은 목표 유전자를 조절하기 위한 functional family일 가능성이 높다. 또한 이러한 functional family는 하나의 전사체로부터 발현되기 때문에, 조직별로 조건별로 같은 발현 패턴을 보여야 한다. 본 연구에서는 발현데이터로부터 microRNA functional family를 탐색하기 위해, 5개의 연구 그룹에서 공개한 조직별 microRNA 발현데이터를 표준화 작업을 거친 후 통합하고 k-nearest neighbor 알고리즘을 이용해 결측치를 보정한 후 microRNA 발현사이의 correlation을 계산한다. 이때 데이터 통합에서 생기는 문제에 robust한 결과를 얻기 위해 실제 발현데이터가 아닌 rank 데이터부터 correlation을 측정한다. 계산된 spearman ranked correlation 결과와 microRNA의 genomic coordination 정보로부터 34개의 functional family를 정의할 수 있었다.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.20 no.3
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• pp.12-19
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• 2006

Micro-source units having power ratings in thousands of watts can provide power quality with higher reliability and efficiency than the conventional large scale units. This paper develops switching level model of micro-source and studies the characteristics of the micro-grid consisting of multiple micro-sources and interfaced with electric power system. The developed model adopts the space vector PWM to fully utilize the capacity of inverter. The interaction of the grid connected micro-sources and the characteristics of the control system parameters are investigated. Micro-sources and micro-grid are implemented using PSCAD/EMTDC. Simulation results show that the proposed model is efficient for studying micro-grid system.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.10 no.1
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• pp.1-7
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• 2011

Micromachining is gaining popularity due to recent advancements in MEMS(Micro Electro Mechanical Systems). Using conventional micromachining, it is relatively difficult to produce moving components in the order of microns. Photolithography for silicon material has high accuracy machining, but it has low aspect ratio. X-ray lithography has ultra high accuracy machining, but it has expensive cost. Micro-EDM(electro discharge machining) has been gaining popularity as a new alternative method to fabricate micro-structures. In this study, Micro-EDM machine is developed available for fabricate micro-structures and two processes such as side cut EDM and milling EDM is proposed. Several sets of experiment results have been performed to study the characteristics of the machining process.

• Transactions of Materials Processing
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• v.11 no.7
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• pp.620-627
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• 2002

The purpose of this paper is the development of an automated measurement system for micro spring based on the digital image processing technique. This micro spring can be used in various engineering applications such as filament, load bearing springs, hard disk suspension and many others. Main functionality of the micro spring inspection system is to measure the representative pitch of the micro spring. The derivative operators are used for edge detection in gray level image. Measurement system developed in this paper consisted of new auto feeding mechanism to take advantage of air pressure. In the process of development of the micro spring inspection system based on the image processing and analysis, strong background technology and know-how have been accumulated to measure micro mechanical parts.

• Journal of Industrial Technology
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• v.23 no.A
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• pp.21-27
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• 2003

The bio-micro pin is usually used for biochemistry analysis. The capability of manufacturing the micro-pin and array with effective and low-cost way is very important to developers. The micro-pin is composed of "sample channel" putting liquid into already fixed volume, "flat tip" having connection with printing quantity, and "head part" for preventing it from rotation of pin in the holder. We analyzed out printing variation in accordance with shape and tip size of the micro-pin point channel, In this study, we suggested the manufacturing progress and shape demand condition of the micro-pin which could put $0.2{\mu}{\ell}$-biochemistry material into the sample volume, and will be able to produce the micro-pin which can put $10n{\ell}$-biochemistry material into the sample volume in the future.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2005.05a
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• pp.278-281
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• 2005

Today, manufacturing capability at the micro or nano scale production field is requested strongly in view of parts and product miniaturization. Miniaturized parts and products will introduce lots of benefits in terms of high precision functionality and low energy consumption. This paper presents the results of micro milling machine tool development for micro machining process. Finite element analysis has been performed to know the relationship between design dimensional variables and structural stiffness in terms of static, dynamic, thermal aspects. Performance evaluation through machining has been tested and discussed for achievable machining characteristics.

• Journal of Integrative Natural Science
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• v.6 no.1
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• pp.12-15
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• 2013

To combine the micro rain radar and microwave radiometer cloud liquid water, we estimate the cloud physical thickness from the difference between the MTSAT-1R cloud top height and cloud base height of visual observation of Daegwallyeong weather station, and the cloud liquid water path of micro rain radar is obtained by multiplying the liquid water content of micro rain radar and the estimated cloud physical thickness. The trend of microwave radiometer liquid water path agrees with that of the micro rain radar during small precipitation. We study these characteristics of micro rain radar and microwave radiometer for small precipitation to obtain the combined cloud water content of micro rain radar and microwave radiometer, constantly operated regardless to the rainfall.

• Journal of the Semiconductor & Display Technology
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• v.10 no.2
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• pp.7-12
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• 2011

In this paper, a laser scattering mechanism are designed to detect micro defects such as dent, scratch, pinhole, etc. Its influential parameters are experimentally selected and scattering patterns of micro defects have been analyzed for silicon wafer in solar cell. As a result of experiments, scattered lights are rather increased in wafer surface with micro defects, in comparison to no micro ones. Scattering parameters are optimally selected for obtaining robust and high quality laser scattering images of micro defects. It is shown that scattered light components are linearly increased according to the increase of micro defect sizes, and the depth of micro-defects give a large influence on optical deflection.

• Journal of Power Electronics
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• v.13 no.2
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• pp.313-321
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• 2013

This paper describes the operation analysis results of a communication-based DC micro-grid using a hardware simulator developed in the lab. The developed hardware simulator is composed of distributed generation devices such as wind power, photovoltaic power and fuel cells, and energy storage devices such as super-capacitors and batteries. Whole system monitoring and control was implemented using a personal computer. The power management scheme was implemented in a main controller based on a TMS320F28335 chip. The main controller is connected with the local controller in each of the distributed generator and energy storage devices through the communication link based on a CAN or an IEC61850. The operation analysis results using the developed hardware simulator confirm the ability of the DC micro-grid to supply the electric power to end users.

• The KSFM Journal of Fluid Machinery
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• v.18 no.4
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• pp.22-29
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• 2015

In this study, an in-house program to predict steady state operation of micro gas turbines is constructed using MATLAB. The program consists of two parts: design and off-design simulations. The program is fully modular in its structure, and performance of each component (compressor, combustor, turbine, recuperative heat exchanger and pipe elements) is calculated in a separate calculation module using mass and energy balances as well as models for off-design characteristics. The off-design modules of compressor and turbine use performance maps, which are program inputs. The off-design operation of a micro gas turbine under development was predicted by the program. The prediction results were compared with those by commercial software, and the validity of the in-house program was confirmed.