• Title/Summary/Keyword: miR27a

Search Result 286, Processing Time 0.024 seconds

Effects of Hearing Handicap on Depression and Self-efficacy in the Elderly at Home (재가노인의 청력장애가 우울과 자기효능감에 미치는 영향)

  • Lee, Young Mi;Ha, Eun-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.20 no.2
    • /
    • pp.571-579
    • /
    • 2019
  • The purpose of this study was to identify levels of hearing handicap, depression, and self-efficacy, and to determine the effect of hearing handicap on depression and self-efficacy in home-based elderly. Data were collected from August to September 2017. Two hundred and seventy eight elderly living at home in three cities participated in this study. Data were analyzed using the independent t-test, one-way ANOVA, Scheffe's test, Pearson's correlation coefficients, and by multiple regression analysis using SPSS Ver. 20.0 for Windows. Mean levels of hearing handicap, depression, and self-efficacy were 10.91 (${\pm}19.83$), 4.75 (${\pm}3.90$), and 46.87 (${\pm}6.75$) respectively. A statistically significant positive correlation was observed between hearing handicap and depression (r=.228, p<.001), and significant negative correlations were found between hearing handicap and self-efficacy (r=-.284, p<.001) and between depression and self-efficacy (r=-.526, p<.001). Hearing handicap had a negative effect on self-efficacy (${\beta}=-.161$, p=.008) and its explanatory power was 27.2%. The study results suggest that the developments of multidisciplinary interventions and education programs are important to prevent or minimize hearing handicap in the elderly.

Community Structure of Fish and Distribution Characteristics of Phoxinus phoxinus and Rhynchocypris kumgangensis in the Gihwacheon Stream of Namhangang River, Korea (남한강 지류 기화천의 어류 군집 구조 및 연준모치와 금강모치의 분포 특성)

  • Jeon, Hyoung-Joo;Baek, Jeong-Ik;Kim, Kyung-Hwan;Kim, Seung-Yong;Lee, Wan-Ok;Kwak, Ihn-Sil;Song, Mi-Young
    • Korean Journal of Ichthyology
    • /
    • v.31 no.2
    • /
    • pp.90-100
    • /
    • 2019
  • This study was carried out from March to November, 2013 to investigate the fish community structure and distribution characteristics of Phoxinus phoxinus and Rhynchocypris kumgangensis appearing in Gihwacheon Stream, Pyeongchang. A total of 6 families and 19 species of fish emerged during the survey period. The dominant species were R. kumgangensis (Individuals 44.7%, Biomass 30.2%) and P. phoxinus (Individuals 27.7%, Biomass 15.9%). Endemic species were 10 species including Pseudopungtungia tenuicorpus, Coreoleuciscus splendidus, Hemibarbus mylodon, Gobiobotia brevibarba, Microphysogobio longidorsalis, R. kumgangensis, Zacco koreanus, Korecobitis rotundicaudata, Iksookimis koreensis and Coreoperca herzi. Endogenous species were P. tenuicorpus, G. brevibarba and P. phoxinus. Hemibarbus mylodon was a natural monument. Oncherhynchus mykiss was exotic species and translocated species was Oncorhynchus masou masou. The dominant species, R. kumgangensis, appeared at all survey sites. Except for St.6, the b value was more than 3.0 and the slope of K value showed positive correlation. P. phoxinus appeared in St. 3~St. 6 and St. 3 and St. 4 only showed stable populations.

Effect of Suicidal Risk, Meaning in Life on Age-dependent Life Respect in Patients at Public Hospital (자살위험성과 생의 의미가 생의 주기별 생명존중인식에 미치는 영향 -공공의료기관 이용환자를 중심으로-)

  • Wang, Mi-Suk;Hwang, Sun-Suk;Jung, Hyun-Chul;Han, Suk-Jung;Kang, Kyung-Ah
    • Journal of Korean Public Health Nursing
    • /
    • v.27 no.1
    • /
    • pp.113-128
    • /
    • 2013
  • Purpose: The purpose of this study was to investigate the degree of suicidal risk, meaning in life, and life respect in various ages of patients and identify factors influencing their life respect. Method: The participants were 229 patients in a public hospital who completed questionnaires. Data were analyzed using descriptive statistics, t-test, Fisher's exact test, ANOVA with Duncan post hoc test, and multiple regression. Results: There was a negative correlation between the meaning of life and life respect in the old age group (r=-.23, p=.02) and all subjects (r=-.14, p=.01) after controlling for age. Factors significantly influencing life respect were gender (${\beta}$=0.11, p=.050) and educational status (${\beta}$=-0.17, p=.022), and the multiple regression model explained 16.7% of the variance in all subjects (p<.001). In the early adulthood group, factors significantly influencing the life respect were gender (${\beta}$=0.18, p<.001) and suicidal thoughts (${\beta}$=0.21, p=.028), and the multiple regression model explained 6.8% of variance in all subjects (p=.001). Conclusion: The results of this study suggest that suicidal prevention and educational programs for increasing an appreciation of life should consider subject's characteristics, such as gender and educational status.

Correlation among Depression, Death Anxiety, and Quality of Life of Aged Women (여성노인의 우울, 죽음불안, 삶의 질의 관계)

  • Park, Kyung-Eun;Kwon, Mi-Hyoung;Kwon, Young-Eun
    • Journal of Korean Public Health Nursing
    • /
    • v.27 no.3
    • /
    • pp.527-538
    • /
    • 2013
  • Purpose: This study was conducted in order to provide basic data for development of a nursing intervention program needed in living successfully in elderly women's later years by examining the relationship among depression, death anxiety, and quality of life of elderly women. Methods: Subjects were 115 elderly women over 65 years old who were capable of verbal/nonverbal communication and could understand/answer the questionnaire in H region. Data collection was conducted after receiving written consent using a structured questionnaire. The data analysis was performed using descriptive statistics, t-test, ANOVA, Duncan's multiple range test and Pearson's Correlation Coefficient using the SPSS 12.0/WIN program. Results: Results of this study showed that the degree of depression in elderly women was $4.14{\pm}3.22$ on average and the degrees of death anxiety and quality of life were $2.41{\pm}0.55$ and $3.72{\pm}0.59$ on average, respectively. No significant correlation was observed between depression and death anxiety however, depression showed negative correlation (r=-.448, p<.001) with quality of life and death anxiety also showed negative correlation (r=-.219, p<.05) with quality of life. Conclusion: We can predict that depression and death anxiety negatively affect quality of life of elderly women.

DETECTION OF BLACK-PIGMENTED BACTERIA IN INFECTED ROOT CANALS (감염근관에서 Black-Pigmented Bacteria의 동정에 대한 연구)

  • Kwon, Eun-Kyoung;Kim, Eun-Sook;Kwak, Ju-Seog;Lee, Hwang;Lee, Su-Jong;Im, Mi-Kyung
    • Restorative Dentistry and Endodontics
    • /
    • v.27 no.1
    • /
    • pp.54-65
    • /
    • 2002
  • Black-pigmented bacteria have been implicated in the endodontic infections. This group of microorganisms includes Porphyromonas endodontalis, Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens. The organisms display a wide variety of virulence factors that may be pertinent to acute endodontic infections. The aim of this study was to identify P. endodontalis, P. gingivalis, P. intermedia, and P. nigrescens by using special potency disk test, filter paper spot test, 165 rRNA gene-directed PCR, and API 32A. Microbial samples were collected from root canals of 33 intact teeth with necrotic pulp and/or apical periodontitis. Conventional laboratory methods were used for identification of the strains of black pigmented bacteria. Eighteen of 33 samples were positive for the growth of black-pigmented bacteria Five colonies were cultured from each pure cultured colonies from Brucella agar plate. Seventy seven colonies were positive for the growth of black-pigmented bacteria. Thirty three of 77(42.6%) were identifed as P. nigrescens, 10 of 77(12.9%)were P. gingivalis, 6 of 77(7.8%) were P. endodontalis, 10 of 77(12.9%) were P. intermedia. On the contrary the reference strains of P. nigrescens, experimental strains of P nigrescens was sensitive to kanamycin in special potency disk test. 165 rRNA gene PCR and API test after rapid presumptative identification methods, such as special potency disk test and filter paper spot test, would be accurate detection methods for black-pigemented bacteria.

Chronic Fatigue and Related Factors in Adults (성인의 만성피로와 그 관련 요인에 대한 연구)

  • Byun Young-Soon;Park Mi-Sook
    • Journal of Korean Academy of Fundamentals of Nursing
    • /
    • v.8 no.3
    • /
    • pp.302-313
    • /
    • 2001
  • Purpose: To identify characteristics of chronic fatigue, difference between the duration of fatigue and characteristics of chronic fatigue, and association between chronic fatigue and related factors in adults. Method: The subjects for this study were 180 adults who had experienced fatigue for over one month The measurement tools were the Revised Fatigue Scale by Chalder et al. (1993), the Visual Analogue Scale-energy developed by Lee et al. (1991), the BEPSI (Brief Encounter Psychosocial Instrument) by Frank & Zyzanski (1988), Zung's self rating depression scale (1965) and life style items including exercise sleep, drinking smoking and diet as developed by the researchers. Results : Those who complained of fatigue over six months experienced higher disturbances in their daily life compared to those who had suffered from fatigue less than six months. There were a significant correlation between severity of fatigue and depression (r=.46, p<.001), stress (r=.41, p<.001), and sleep (r=.20, p<.01) Statistically significant relationships were found between severity of fatigue and amount of exercise per week (F=3.79. p<.05) disturbed sleep (t=-2.66, p<.01), number of times awakened during the night (F=3.48, p<.05) types of drinking (F=2.65, p<.05), and diet regularity (F=5.83, p<.01). The construction of a multiple regression model revealed an adjusted $R^2$ of .27 with the depression score serving the major predictor variables for severity of fatigue. Men and people in the younger age group were more energetic than women and those in other age groups. Also married people experienced more fatigue than people who were single. divorced or separated. Conclusion: In nursing interventions for fatigue, medical personnel should consider sociodemographic characteristics of the clients, ways to reduce of stress and counter disturbances in daily life and develop strategies for a health promoting life style.

  • PDF

First Record of Two Euplotes Ciliates (Ciliophora: Spirotrichea: Euplotida) from Korea

  • Park, Mi-Hyun;Kim, Se-Joo;Min, Gi-Sik
    • Animal Systematics, Evolution and Diversity
    • /
    • v.26 no.1
    • /
    • pp.21-27
    • /
    • 2010
  • Two marine euplotid ciliates, i.e. Euplotes cristatus Kahl, 1932 and E. minuta Yocom, 1930, were collected from the public waterfront of Incheon on the Yellow Sea and from the Songjeong Beach, Busan, in the Strait of Korea, respectively. These two species were verified as unrecorded species in Korea. These species were described based on live observation, protargol impregnation, and silver nitrate impregnation. In addition, the small subunit ribosomal DNA (SSU rDNA) sequences of the two species were compared with previously known sequences of the Euplotes species. Euplotes cristatus has an elongated oval form, size in vivo of $60-84{\times}38-68\;{\mu}m$, 35-50 adoral zone of membranelles (AZM), 10 frontoventral cirri (FVC), 5 transverse cirri (TC), 4-5 caudal cirri (CC), 8 dorsal kineties (DK), 10-16 dorsal cilia of middle DK, and silverline system of single-vannus type. Euplotes minuta has a small ovoid form ($44-53{\times}26-35\;{\mu}m$ in vivo), 31-41 AZM, 10 FVC, 5 TC, 4 CC, 9 DK, 10-12 dorsal cilia of middle DK, and silverline system of single-vannus type.

Relationship between Musculoskeletal Pain and Job Satisfaction of the Physical Therapists in Elderly Care Facilities (노인요양시설 물리치료사의 근골격계 통증과 직무만족도의 관련성 연구)

  • Lee, Kyoung-Suk;Lee, Wan-Hee;Yun, Mi-Jung
    • The Korean Journal of Health Service Management
    • /
    • v.6 no.4
    • /
    • pp.49-60
    • /
    • 2012
  • The purpose of this study aim to analyze factors that influence the job satisfaction of physical therapist in working in Elderly Care Facilities. The participants were 173 physical therapist was using a self-administered questionnaire. Data was collected from June 12 to 15, 2012 and analyzed by SPSS 12.0. The average physical therapist's job satisfaction was $3.27{\pm}.49$ points. There was significant difference according to work motivation in job satisfaction. 83.4% of participants felt pain. The major causes of the pain were 'repeating the same job constantly(25.5%).' There were statistically significant correlations between pain on movement patterns(r=-.163, p<0.01), duration of pain(r=-.174, p<0.01) and job satisfaction. Multiple regression analysis revealed that job satisfaction became significantly high with work motivation is more definitely. It is necessary to develop job satisfaction management program and musculoskeletal pain policy for physical therapist.

Comparison of Biological Activities of Korean Halophytes

  • Lee, Jeong Min;Yim, Mi-Jin;Lee, Dae-Sung;Lee, Myeong Seok;Park, Yun Gyeong;Jeon, Jae Hyuk;Choi, Grace
    • Natural Product Sciences
    • /
    • v.24 no.4
    • /
    • pp.247-252
    • /
    • 2018
  • Halophytes are expected to possess abundant secondary metabolites and various biological activities because of habitat in extreme environments. In this study, we collected 14 halophytes (Asparagus oligoclonos, Calystegia soldanella, Carex pumila, Chenopodium glaucum, Elymus mollis, Glehnia littoralis, Limonium tetragonum, Messerschmidia sibirica, Rosa rugosa, Salsola komarovii, Spergularia marina, Suaeda glauca, Suaeda maritima, and Vitex rotundifolia) native to Korea and compared their total polyphenol contents, antioxidant and anti-inflammatory activities. The total polyphenol contents of R. rugosa (27.28%) and L. tetragonum (13.17%) were significantly higher than those of the other 12 halophytes and L. tetragonum, R. rugosa, and M. sibirica showed significantly greater antioxidant activities than the other 11 halophytes, as determined by DPPH (2,2-diphenyl-1-picrylhydrazyl). A. oligoclonos, E. mollis, and C. pumila showed significantly greater anti-inflammatory activities than the other 11, as determined by NO (Nitric oxide) and $PGE_2$ (Prostaglandin $E_2$) levels. In contrast, these three extracts had normal and low total polyphenol contents among the 14 halophytes. Consequently, the total polyphenol content in the 14 studied halophytes appeared to be related to antioxidant, but not anti-inflammatory activity levels.

Near Infrared Reflectance Spectroscopy for Non-Invasive Measuring of Internal Quality of Apple Fruit

  • Sohn, Mi-Ryeong;Park, Woo-Churl;Cho, Rae-Kwang
    • Near Infrared Analysis
    • /
    • v.1 no.1
    • /
    • pp.27-30
    • /
    • 2000
  • In this study, we investigated the feasibility of non-destructive determination of internal quality factors of Fuji apple fruit using near infrared(NIR) reflectance spectroscopy and developed the calibration models. As the reference methods, refractometer, titration and texture analyzer for sugar content, acidity and firmness were used, respectively. Samples were scanned from 1100∼2500nm with InfraAlyzer 500C spectrometer and SESAME software was used for data analysis. A multiple linear regression(MLR) analysis was performed to develop the calibrations. The correlation coefficient(R) and standard error of prediction(SEP) were as follows; 0.91, 0.41$^{\circ}$Brix for sugar content, 0.90, 0.04% for acidity and 0.84, 0.094 kg for firmness, respectively. This study shows that NIR spectroscopy can be used to evaluate the sugar content acidity and firmness of apple fruit with acceptable accuracy.