• Journal of Digital Convergence
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• v.11 no.1
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• pp.315-320
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• 2013

We have investigated the variation of spherical aberration of the anterior and posterior surface in a Korean sample population with various age between 20 to 71 years old. We used Pentacam (Oculus Inc., Germany) to measure the corneal radius, asphericity, and spherical aberration of 290 patients with normal cornea. There were negative correlation between corneal anterior radius and spherical aberration(r = -0.22, p<0.0001), and, there were negative correlation between corneal posterior radius and spherical aberration(r=-0.27, p < 0.0001). There were positive correlation between anterior asphericity and spherical aberration(r = 0.24, p < 0.0001), however there were negative correlation between posterior asphericity and spherical aberration(r = -0.17, p=0.00288).The average of anterior spherical aberration and posterior spherical aberration was $0.482{\pm}0.099{\mu}m$ and $-0.098{\pm}0.029{\mu}m$. The average of spherical aberration was $0.385{\pm}0.097{\mu}m$. There were significant positive correlations between anterior spherical aberration and age(r = 0.227, p<0.0001), and there were positive correlations between posterior aberration and age(r = 0.349, p<0.0001). It is considered that this data can be used as basic information for furture studies for improving the quality of vision of modern human and, through the analysis of the spherical aberration of cornea was to provide a better understanding of the optical part of the Korean's eye.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.429-437
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• 2019

This study was a descriptive study to investigate the factors influencing on attitude toward withdrawal of life-sustaining treatment of nursing students' consciousness of biomedical ethics, good death recognition and meaning of life. The subjects of this study were 293 nursing students attending college at P city. Data were collected for two weeks from May 1, 2018 to May 11, 2018. The statistical method was performed with SPSS WIN 22.0 using a complex sampling analysis, pearson's correlation coefficients, and a multiple regression analysis. The result of this study was significant positive correlation between attitude toward withdrawal of life-sustaining treatment and consciousness of biomedical ethics(r=.266, p<.001), good death recognition(r=.373, p<.001), meaning of life(r=.122, p=.037). The meaning of life was significant positive correlation consciousness of biomedical ethics(r=.294, p<.001), good death recognition(r=.230, p<.001). The good death recognition was significant positive correlation consciousness of biomedical ethics(r=.306, p<.001). Factors Influencing on the attitude toward withdrawal of life-sustaining treatment was good death recognition(${\beta}=.32$, p<.001) and consciousness of biomedical ethics(${\beta}=.16$, p=.004). These factors explained about 16% of the variance. Therefore it is necessary to develop an educational program to positively raise the attitude of consciousness of biomedical ethics and good death recognition.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1998.11a
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• pp.137-137
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• 1998

Stability, efficacy, absorption and toxicity of a new nasal spray formulation including salmon calcitonin were studied in the laboratory animals. After the effects of many excipients on the stability of salmon calcitonin were evaluated using HPLC system, we selected taurine. Our experimental composition of salmon calcitonin contains taurine as a stabilizer and HPMC (hydroxypropylmethyl cellulose) as an adhesive polymer. After intranasal administration of salmon calcitonin formulations, Mia$\^$(R)/, Men$\^$(R)/ and experimental composition, 22 IU to rats, the reduction percentages of calcium concentration in plasma (ΔD%) were 16.3%, 12.9% and 20.8%, respectively. After intranasal administration of Mia$\^$(R)/, Men$\^$(R)/ and experimental composition to rats, C$\sub$MAX/ (205${\pm}$161, 244${\pm}$117, and 330${\pm}$202 pg/$m\ell$, respectively) and AUC (41585${\pm}$22070, 41191${\pm}$19125, and 63357${\pm}$43126 pg. min/$m\ell$, respectively) were calculated. The permeation coefficients 10$\^$-7/,cm/sec) of salmon calcitonin in Mia$\^$(R)/, Men$\^$(R)/ and experimental composition using Ussing chamber with rabbit nasal mucosa were 4.7${\pm}$1.5, 0.75${\pm}$0.4 and 5.3${\pm}$1.1, respectively. The experimental composition with taurine and HPMC was proved to be excellent because it improved the stability of salmon calcitonin and inhanced the absorption of salmon calcitonin and was not irritative to the nasal mucosa.

• Journal of Wellbeing Management and Applied Psychology
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• v.6 no.4
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• pp.51-61
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• 2023

Purpose: This study aims to provide basic data to improve disaster nursing competency by identifying nursing students' disaster awareness, disaster preparedness, and disaster nursing competency and confirming the relationship among them. Research design, data, and methodology: The subjects of this study were 310 students attending the Department of Nursing at E University in Gyeonggi-do, and the data was collected from April 13 to May 24, 2023. Results: Disaster awareness averaged 72.91±7.46 points, disaster preparedness averaged 2.82±2.81 points, and disaster nursing competency averaged 44.11±10.76 points. Disaster preparedness and disaster nursing competency were significantly higher in subjects with disaster nursing education experience than in those without experience. Disaster awareness showed a significant positive correlation with disaster preparedness (r=.20, p <.001), and also with disaster nursing competency (r=.37, p <.001). Disaster preparedness showed a significant positive correlation with disaster nursing competency (r=.49, p <.001). It was found that the disaster nursing competency was high when the disaster awareness (B=0.472, p<.001), and the disaster preparedness (B=1.561, p<.001) was high. Conclusions: The results show it is possible to improve students' disaster nursing competency by strengthening education on disaster awareness and disaster preparedness. Thus, specific efforts and future research are needed to develop disaster nursing education.

• The Journal of the Convergence on Culture Technology
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• v.7 no.4
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• pp.105-112
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• 2021

The purpose of this study was to investigate the influence of Consciousness of biomedical ethics on nursing professionalism among nursing students. Data were collected among 192 nursing students in G city, from May 20 to 27, 2021. The collected data was analyzed a using t-test, One way ANOVA, Pearson's correation coeffcient and Stepwise multiple regression using SPSS 20.0 WIN program. The average score for Consciousness of biomedical ethics was 3.28±0.41 and nursing professionalism was 3.32±0.85. nursing professionalism showed a positve correlation(r=.55, p=.000) with Consciousness of biomedical ethics, Models including the variables, Organ transplant, Euthanasia, explained 37%, 16.5% of the variance in the nursing professionalism. Based on the outcome of this study, steps should be taken to design intervention program that emphasize a improve nursing professionalism for nursing students.

• The Korea Journal of Herbology
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• v.20 no.4
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• pp.1-10
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• 2005

Objectives : We investigated the anti-aging effect on skin with the extract of the needles of red pine, Pinus densiflora. Methods : We measured various effects related to skin such as the anti-oxidant effect, the protection against ultraviolet (UV) irradiation, the inhibition of reactive oxygen species (ROS) generation, the induction of heat shock protein 70 (HSP70), the reduction of matrix metalloproteinase-2 (MMP-2) synthesis and senescent cell. Results : The results were as follows : The extract of the needles of red pine (RP) had the potent anti-oxidant effect and the ROS scavenging effect. Also RP preserved the systemic anti-oxidant enzyme system (superoxide dismutase and catalase) from UVB irradiation. RP protected the cell membrane from the damages induced by UVB irradiation. RP induced HSP70, a mediator of resistance to UVB irradiation. RP reduced the synthesis of MMP-2 induced by UVB irradiation. And RP inhibited the amount of senescent-associated (SA) ${\beta}-galactosidase$ staining, as a marker of replicative senescence. Conclusions : The results of our study indicate that the extract of the needles of red pine, Pinus densiflora, has anti-aging effects on skin.

• Journal of Korean society of Dental Hygiene
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• v.14 no.3
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• pp.303-310
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• 2014

Objectives : The purpose of the study is to investigate the effects of bite force by gender and physical features. Methods : A self-reported questionnaire was filled out by 212 college students in Chungnam province from October to December, 2013. The questionnaire consisted of oral health condition. The bite force of the first molar teeth was measured. Results : Males showed the greater bite force than females(p<0.001). Those who had temporomandibular joint(TMJ) disorder suffered from mouth opening difficulty and weaker bite force than those who had not(p<0.05). Those who had malocclusion showed weaker bite force (p<0.01). Those who had a habit of chewing gums tended to have greater bite force than those who had not(p<0.05). The bite force was correlated with height(r=0.309), weight(r=0.345), and BMI(r=0.249)(p<0.01). Conclusions : Males showed greater bite force than females. The temporomandibular joint (TMJ) disorder, subjective malocclusion, and eating habit also affected the bite force.

• The Journal of Korean Medicine
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• v.31 no.4
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• pp.20-37
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• 2010

Objective: This study was performed to investigate the effect of Yagwan-cheunghyeoltang (YCT) on insulin secretion in RIN-m5F cells. Methods: After treatment with various concentrations of YCT to RIN-m5F cells, cell viability, free radical-scavenging activity, SOD activity, and insulin secretion were measured. Additionally, insulin-related gene expressions were measured using real-time RT-PCR. Results: 1. YCT didn't show any influence on RIN-m5F cells viability. 2. YCT showed free radical-scavenging activity by 16% at $100{\mu}g/m{\ell}$ of concentration. 3. YCT showed enhancement of SOD activity by 60% at $100{\mu}g/m{\ell}$ of concentration. 4. YCT significantly increased insulin secretion in RIN-m5F cells in a dose-dependent manner. 5. YCT up-regulated INS-1, INS-2, IRS-1, IRS-2 and IRS-3 mRNA expressions compared to the control group. 6. YCT down-regulated INS-R, GCK, GLP-1R and GLP-2R mRNA expressions compared to the control group. Conclusion: YCT has pharmaceutical properties enhancing insulin production and controlling glucose-associated metabolism, and could be a candidate for drug development after further research.

• Child Health Nursing Research
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• v.17 no.4
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• pp.272-280
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• 2011

Purpose: This study was conducted to survey knowledge, compliance, and quality of life of mothers who have children with atopic dermatitis, and to determine whether above mentioned factors influence each other. Methods: The participants in this study were 165 mothers of children with atopic dermatitis recruited from one out-patient clinic in a hospital in Seoul. The data were collected between March 8, and April 16, 2010 using a structured questionnaire. Results: The mean score for participants' knowledge was 4.17/5, for compliance, 4.27/5 and for quality of life, 3.42/5. Among the five domains of quality of life, emotional status had the lowest score (3.20/5). Knowledge was significantly correlated with compliance (r=.215, p<.005). However, quality of life was not correlated with knowledge (r=-.069) and compliance (r=-.077). Conclusion: Accurate knowledge affects compliance of mothers of children with atopic dermatitis. Therefore, to increase the level of compliance, it is necessary to enhance the knowledge of the mothers. Results also suggest that interventions are needed to improve poor quality of life, particularly the emotional condition of mothers of children with atopic dermatitis.

• Journal of Korean Public Health Nursing
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• v.37 no.2
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• pp.193-204
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• 2023

Purpose: This study was undertaken to identify the association between CPR knowledge, attitude, and teacher efficacy on the performance confidence of CPR. We further investigated methods to enhance the performance ability of CPR among elementary, middle, and high school teachers. Methods: The study design was a descriptive survey conducted from October 15 to December 31, 2022, enrolling 155 elementary, middle, and high school teachers. The data were analyzed by applying Multiple regression, Pearson's correlation coefficient, one way ANOVA and Scheffé test using the SPSS/WIN 23.0 program. Results: The performance confidence of CPR among elementary, middle, and high school teachers showed a significant positive correlation with CPR knowledge (r=.49, p<.001), CPR attitude (r=.26, p<.001), and teacher efficacy (r=.25, p=.002). The factors affecting performance confidence in CPR were CPR knowledge (β=.49, p<.001), gender (β=-.26, p<.001), CPR attitude (β=.20, p=.003), health status (β=.14, p=.038), and teacher efficacy (β=.14, p=.032); these factors explained 40.5%. Conclusion: Results from the study indicate that performance confidence of CPR can be enhanced by providing frequent education on CPR knowledge and attitudes. Moreover, educational programs will aid in maintaining good health and enhance teacher efficacy.