The Korea Journal of Herbology (대한본초학회지)
- Volume 20 Issue 4
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- Pages.1-10
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- 2005
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
Anti-aging Effect on Skin with the needles of red pine, Pinus densiflora
적송엽(赤松葉)이 피부(皮膚)의 노화(老化)에 미치는 영향(影響)
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Park, Seong-Kyu
(Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER,Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
- Lee, Jong-Chan (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
- Ahn, Soo-Mi (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
- Lee, Jin-Young (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
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Kim, Youn-Joon
(Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
- Hwang, Jae-Sung (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
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Lee, Byeong-Gon
(Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
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Chang, Ih-Seoup
(Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER)
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박성규
((주)태평양 기술연구원 피부과학연구소,경희대학교 한의과대학 방제학교실) ;
- 이종찬 ((주)태평양 기술연구원 피부과학연구소) ;
- 안수미 ((주)태평양 기술연구원 피부과학연구소) ;
- 이진영 ((주)태평양 기술연구원 피부과학연구소) ;
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김연준
((주)태평양 기술연구원 피부과학연구소) ;
- 황재성 ((주)태평양 기술연구원 피부과학연구소) ;
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이병곤
((주)태평양 기술연구원 피부과학연구소) ;
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장이섭
((주)태평양 기술연구원 피부과학연구소)
- Published : 2005.12.30
Abstract
Objectives : We investigated the anti-aging effect on skin with the extract of the needles of red pine, Pinus densiflora. Methods : We measured various effects related to skin such as the anti-oxidant effect, the protection against ultraviolet (UV) irradiation, the inhibition of reactive oxygen species (ROS) generation, the induction of heat shock protein 70 (HSP70), the reduction of matrix metalloproteinase-2 (MMP-2) synthesis and senescent cell. Results : The results were as follows : The extract of the needles of red pine (RP) had the potent anti-oxidant effect and the ROS scavenging effect. Also RP preserved the systemic anti-oxidant enzyme system (superoxide dismutase and catalase) from UVB irradiation. RP protected the cell membrane from the damages induced by UVB irradiation. RP induced HSP70, a mediator of resistance to UVB irradiation. RP reduced the synthesis of MMP-2 induced by UVB irradiation. And RP inhibited the amount of senescent-associated (SA)