• Journal of Digital Convergence
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• v.15 no.9
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• pp.261-271
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• 2017

This study was conducted to identify sexual knowledge, sexual attitude, and sexual behavior that are perceived by psychiatric patients, and analyzes their differences and relations. Participants were 222 adult psychiatric patients hospitalized in two psychiatric hospitals located at K city of J province. Data were collected from March 11 to April 15, 2016 by using structured questionnaires. Collected data were analyzed through independent t-test, One-way ANOVA, $Scheff{\acute{e}}$ test, Pearson's Correlation Coefficients using SPSS/WIN 20.0 program. The mean score of sexual knowledge was 2.60, sexual attitude was 2.74, and sexual behavior was 0.49. The sexual knowledge of patients differed significantly according to parent attitude(${\rho}$<.01), and sexual behavior showed the difference according to diagnosis(${\rho}$<.05). Sexual knowledge had a significant positive correlation with sexual attitude(r=.75, ${\rho}$<.001) and sexual behavior(r=.15, ${\rho}$<.05). There were also positive correlation between the sexual attitude and active sexual behaviour(r=.20, ${\rho}$<.01), the subcategory of sexual behaviour. These results of study suggest that psychiatric nurses should appropriately assess sexual problems of psychiatric patients and include them in nursing interventions.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6505-6510
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• 2014

Objective: This study was conducted to identify whether polymorphic variants of set domain-containing protein 8 (SET8) and tumor protein p53 (TP53) codon 72, either independently or jointly, might be associated with increased risk for cervical cancer. Methods: We genotyped SET8 and TP53 codon 72 polymorphisms of peripheral blood DNA from 114 cervical cancer patients and 200 controls using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and direct DNA sequencing. Results: The frequency of SET8 CC (odds ratios (OR) = 2.717, 95% CI=1.436-5.141) or TP53 GG (OR=2.168, 95% CI=1.149-4.089) genotype was associated with an increased risk of cervical cancer on comparison with the SET8 TT or TP53 CC genotypes, respectively. In additional, interaction between the SET8 and TP53 polymorphisms increased the risk of cervical cancer in a synergistic manner, with the OR being 9.913 (95% CI=2.028-48.459) for subjects carrying both SET8 CC and TP53 GG genotypes. Conclusion: These data suggest that there are significant associations between the miR-502-binding site SNP in the 3'-UTR of SET8 and the TP53 codon 72 polymorphism with cervical cancer in Chinese, and there is a gene-gene interaction.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.46 no.3
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• pp.241-247
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• 2001

Boundary line method was adopted to analyze the relationships between rice yield and meteorological conditions during rice growing period. Boundary lines of yield responses to mean temperature($T_a$) and sunshine hour( $S_{h}$) and diurnal temperature range($T_r$) were well-fitted to hyperbolic functions of f($T_a$) =$$\beta$_{0t}$(1-EXP(-$$\beta$_{1t}$ $\times$ ($T_a$) ) and f( $S_{h}$)=$$\beta$_{0t}$((1-EXP($$\beta$_{1t}$$\times$ $S_{h}$)), to quadratic function of f($T_r$) =$\beta$$_{0r}$(1-($T_r$ 1r)$^2$), respectively. to take into account to, the sterility caused by low temperature during reproductive stage, cooling degree days [$T_c$ =$\Sigma$(20-$T_a$] for 30 days before heading were calculated. Boundary lines of yield responses to $T_c$ were fitted well to exponential function of f($T_c$) )=$\beta$$_{0c}$exp(-$$\beta$_{1c}$$\times$$T_c$ ). Excluding the constants of $\beta$$_{0s}$ from the boundary line functions, formed are the relative function values in the range of 0 to 1. And these were used as yield indices of the meteorological elements which indicate the degree of influence on rice yield. Assuming that the meteorological elements act multiplicatively and independently from each other, meteorological yield index (MIY) was calculated by the geometric mean of indices for each meteorological elements. MIY in each growth period showed good linear relationship with rice yield. The MIY's during 31 to 45 days after transplanting(DAT) in vegetative stage, during 30 to 16 days before heading (DBH) in reproductive stage and during 20 days after heading (DAH) in ripening stage showed greater explainablity for yield variation in each growth stage. MIY for the whole growth period was calculated by the following three methods of geometric mean of the indices for vegetative stage (MIVG), reproductive stage (HIRG) and ripening stage (HIRS). MI $Y_{I}$ was calculated by the geometric mean of meteorological indices showing the highest determination coefficient n each growth stage of rice. That is, (equation omitted) was calculated by the geometric mean of all the MIY's for all the growth periods devided into 15 to 20 days intervals from transplanting to 40 DAH. MI $Y_{III}$ was calculated by the geometric mean of MIY's for 45 days of vegetative stage (MIV $G_{0-45}$ ), 30 days of reproductive stage (MIR $G_{30-0}$) and 40 days of ripening stage (MIR $S_{0-40}$). MI $Y_{I}$, MI $Y_{II}$ and MI $Y_{III}$ showed good linear relationships with grain yield, the coefficients of determination being 0.651, 0.670 and 0.613, respectively.and 0.613, respectively.

• Biomolecules & Therapeutics
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• v.23 no.2
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• pp.189-194
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• 2015

P450 1A2 is responsible for the metabolism of clinically important drugs and the metabolic activation of environmental chemicals. Genetic variations of P450 1A2 can influence its ability to perform these functions, and thus, this study aimed to characterize the functional significance of three P450 1A2 allelic variants containing nonsynonymous single nucleotide polymorphisms (P450 $1A2^*8$, R456H; $^*15$, P42R; $^*16$, R377Q). Variants containing these SNPs were constructed and the recombinant enzymes were expressed and purified in Escherichia coli. Only the P42R variant displayed the typical CO-binding spectrum indicating a P450 holoenzyme with an expression level of ~ 170 nmol per liter culture, but no P450 spectra were observed for the two other variants. Western blot analysis revealed that the level of expression for the P42R variant was lower than that of the wild type, however the expression of variants R456H and R377Q was not detected. Enzyme kinetic analyses indicated that the P42R mutation in P450 1A2 resulted in significant changes in catalytic activities. The P42R variant displayed an increased catalytic turnover numbers ($k_{cat}$) in both of methoxyresorufin O-demethylation and phenacetin O-deethylation. In the case of phenacetin O-deethylation analysis, the overall catalytic efficiency ($k_{cat}/K_m$) increased up to 2.5 fold with a slight increase of its $K_m$ value. This study indicated that the substitution P42R in the N-terminal proline-rich region of P450 contributed to the improvement of catalytic activity albeit the reduction of P450 structural stability or the decrease of substrate affinity. Characterization of these polymorphisms should be carefully examined in terms of the metabolism of many clinical drugs and environmental chemicals.

• Journal of Digital Convergence
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• v.18 no.6
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• pp.353-361
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• 2020

The aim of this study was to identify the factors related to clinical practice stress in nursing college students. The participants comprised 160 students in a nursing college. Data collection was conducted from December 1, 2019 to December 15, 2019. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient and a multiple regression analysis. The average score for clinical practice stress was 3.19 out of a maximum of 5. clinical practice stress had a statistically significant relationship with self-esteem(r=.22, p=.005), nursing professionalism(r=-.26, p=.001) and cognitive emotion control strategy(r=.38, p<.001). The factors affecting clinical practice stress were maladaptive cognitive emotion control strategy(β=.46, p<.001), nursing professionalism(β=-.20, <.001), grade(β=.20, p=.002), motivation for nursing choice(β=-.15, p=.019); the explanatory power of the model was 35.5%. Therefore, in order to reduce the stress on clinical practice, it is necessary to develop a program that can lower the maladaptive cognitive emotion control strategy along with improving the nursing professionalism in stress situations.

• Journal of Yeungnam Medical Science
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• v.4 no.1
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• pp.1-15
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• 1987

Magnetic Resonance (M.R.) is rapidly emerging technique that provides high quality images and potentially provides much more diagnostic information than do conventional imaging modalities. M.R.I. is conceptually quite different from currently used imaging methods. The complex nature of M.R.I. allows a great deal of flexibility in image product ion and available information, and key points are as follows. 1. M.R.I. offers a non-invasive technique with which to gene rate in vivo human images without ionizing radiation and with no known adverse biological effects. 2. Imaging mechanism of M.R.I. is quite different from conventional imaging modality and for more accurate diagnostic application, It is necessary for physician to understand imaging mechanism of M.R.I. 3. M.R. makes available basic chemical parameters that may provide to be useful for diagnostic medical imaging and more specific pathophysiologic information which are not available by alternate techniques. 4. M.R. can be produced by number of different methods. This flexibility allows the imaging technique to be applicated for particular clinical purpose. Multiplanar and three dimensional imaging may extend the imaging process beyond the single section available with current CT. 5. Future directions include efforts to; a. Further development of hard ware b. More fasternning scan time c. Respiratory and cardiac gated imaging d. Imaging of additional nuclei except hydrogen e. Further development of contrast media f. M.R. in vivo spectroscopy g. Real time M.R. imaging.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.10 s.89
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• pp.938-943
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• 2004

In this paper, we propose a T-shaped DGS for CPW and provide the closed-form solutions for power loss rate, and bandwidth of the DGS. The proposed T-shaped DGS structure has a range of capacitance(C) 5.5 times wider than the dumbbell-shaped DGS structure. In addition we also analyze relations between R, L, C values of the DGS equivalent circuit and total loss rate, BW, $\omega_0$ of the DGS.

• The Journal of the Korea Contents Association
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• v.15 no.11
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• pp.559-570
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• 2015

As national R&D is increased in scale, technology transfer has garnered more attention in terms of utilizing R&D outcomes. In this study, we analyzed influencing factors to technology transfer, as a way of utilizing R&D results, using data on national R&D. The analyses was performed with 3 subjects: university, government research institute and industry. When royalty is used as a dependent variable to measure the performance outcomes of technology transfers, the analysis showed that R&D funds have positive influence on all three subjects. In terms of government research institute, the influence was significant whether the location is the capital area or Daejeon city. With regards to industry, factors such as whether the project is a cooperative research, applied research, and the research to technology transfer period were found to have remarkable influence. On the other hand, when the number of cases of technology transfer was used as a dependent variable, the analysis indicated that R&D funds have significant impact on university, while for government research institute, the significant influencing factors include both R&D funds and the research to technology transfer period, and for industry have positive influence on applied research. It is therefore necessary to make differentiated policies considering the R&D organizations in order to improve the efficiency of technology transfer performance.

• Journal of Microbiology and Biotechnology
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• v.18 no.5
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• pp.964-967
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• 2008

Two structural protein genes, VP19 and VP466, of white spot syndrome virus (WSSV) were cloned and expressed in Sf21 insect cells using a baculovirus expression system for the development of injection and oral feeding vaccines against WSSV for shrimps. The cumulative mortalities of the shrimps vaccinated by the injection of rVP19 and rVP466 at 15 days after the challenge with WSSV were 50.2% and 51.8%, respectively. For the vaccination by oral feeding of rVP19 and rVP466, the cumulative mortalities were 49.2% and 89.2%, respectively. These results show that protection against WSSV can be generated in the shrimp, using the viral structural protein as a protein vaccine.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.83.3-83.3
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• 2019

New high-resolution spectra and multi-band photometric data of BS Cas were obtained at the Bohyunsan Optical Astronomy Observatory in 2018 and at the Jincheon Station of the Chungbuk National University Observatory in 2011, respectively. We measured the radial velocities (RVs) for both components, and the effective temperature of the more massive star was determined to be $6262{\pm}56K$. In addition, historical light curves showed strong time-dependant light variations at the total eclipse. These variations were modeled by a cool spot on the more massive component. Finally, the physical parameters of BS Cas by a simultaneous analysis of our RV curves with the photometric light curves were presented. Individual masses and radii of both components were deduced as $M_1= 0.59{\pm}0.07M_{\odot}$, $M_2=1.47{\pm}0.15M_{\odot}$, $R_1=0.94{\pm}0.03R_{\odot}$ and $R_2=1.47{\pm}0.05R_{\odot}$.