• Journal of the Architectural Institute of Korea Structure & Construction
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• v.34 no.1
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• pp.27-32
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• 2018

This work provides the analytical methods to represent the updated form of stiffness or flexibility matrices using the measurements of the first few natural frequencies and the corresponding mode shapes. This study derives the mathematical forms on the variance of stiffness or flexibility matrices to minimize the performance index in the satisfaction of the eigen-function including the residual force depending on the measured data. The proposed methods can be utilized in detecting damage and updating the parameter matrices deviated from the analytical parameter matrices. The validity of the proposed methods is investigated in a numerical experiment of truss structure and the numerical results of stiffness-based and flexibility-based methods are compared. The sensitivity to the external noise is also examined for applying to the practical work.

• Structural Engineering and Mechanics
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• v.64 no.3
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• pp.311-321
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• 2017

This paper presents the details of analytical studies carried out towards the prediction of flexural capacity and load-deflection behaviour of Laced Steel-Concrete Composite (LSCC) beams. Analytical expressions for flexural capacity of the beams are derived in accordance with the basic principles of conventional Reinforced Concrete (RC) beams, but incorporated with relevant modifications to account for the composite nature of the cross-section. The ultimate flexural capacity of the two LSCC beams predicted using the derived expressions is found to be approximately 20% lower than those obtained due to measurement from experiments. Further to these, two simple methods are also proposed on the basis of unit load method and equivalent steel beam method to determine the non-linear load-deflection response of the LSCC beams for monotonic loading. Upon validation of the proposed methods by comparing the predicted responses with those of experiments and finite element analysis, it is found that the methods are useful to find nonlinear response of such composite beams.

• Journal of Food Hygiene and Safety
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• v.3 no.4
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• pp.203-209
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• 1988

This study was performed to develop the simple and rapid determination method of preservatives in Yogurt and Soybean.sauce. 1. The analytical method by HPLC system was as follow: The sample was diluted, centrifuged, filtered, if necessary, and analyzed by HPLC system with UV detector. 2. The analytical method by GLC system was as follow: The sample was extracted directly with ether, added cone. sulfuric acid to destroy emulsion and analyzed by the GLC system with FID. 3. The recovery rates of preservatives by the above methods were higher than 99.0 %. 4. Total running time for the above methods was less than 50 minutes. Especially, the running time for dilution method by HPLC system was one-third of that for GLC method.

• Structural Engineering and Mechanics
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• v.13 no.2
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• pp.211-230
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• 2002

The objective of this study is to investigate the dynamic behavior of elastic beams subjected to moving loads. Although analytical methods are available, they have limitations with respect to complicated structures. The use of computer technology in recent years is an effective way to solve the problem; thus using the latest technology this study establishes a finite-element solution procedure to investigate dynamic behaviors of a typical elastic beam having a set of constant geometric properties and various span lengths. Both the dead load of the beam and traffic load are applied in which the traffic load is considered a concentrated moving force with various traveling passage speeds on the beam. Dynamic behaviors including deflection, shear, and bending moment due to moving loads are obtained by both analytical and finite element methods; for simple structures, they have an excellent agreement. The numerical results show that based on analytical methods the fundamental mode is good enough to estimate the dynamic deflection along the beam, but is not sufficient to simulate the total response of the shear force or the bending moment. The linear dynamic behavior of the elastic beams subjected to multiple exciting loads can easily be found by linear superposition, and the geometric nonlinear results caused by large deformation and axial force of the beam are always underestimated with only a few exceptions which are indicated. In order to make the results useful, they have been nondimensionalized and presented in graphical form.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.30 no.1
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• pp.58-66
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• 2020

Objectives: The objective of this study was to develop formaldehyde samples for quality control (QC) and to test the applicability of proficiency analytical testing in Korea. Methods: We made formaldehyde samples with certified standard solutions (formaldehyde in water or acetonitrile) and 2,4-dinitrophenylhydrazine (2,4-DNPH)-coated silicagel tubes. Four levels of formaldehyde concentration were tested for storage stability at room temperature and at 4℃ over three months. Analytical proficiency testing was performed with four or 36 institutes. Results: Formaldehyde sample tubes were easily made through the injection of standard solutions and the average efficiencies of recovery were 95-101%. The coefficients of variation (CV) of the formaldehyde samples were 1.39-2.55%. The recovery efficiencies fell between 90% and 110% at the concentration range of 1-10 ㎍/sample over three months storage at refrigerated and room temperature. The CVs were less than 5% in the proficiency analytical testing. By adjusted proficient ranges, 64% of the results of the second proficiency analytical testing were acceptable. Conclusions: The formaldehyde samples made by injection on 2,4-DNPH-coated silicagel tubes were stable and applicable for quality control.

• Ocean Systems Engineering
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• v.3 no.2
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• pp.79-95
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• 2013

Suction anchors are widely adopted in mooring systems. However there are still challenges in predicting the failure mode and ultimate pullout capacity of the anchor. Previously published methods for predicting the inclined pullout capacity of suction anchors are mainly based on experimental data or the FEM analysis. In the present work, an analytical method that is capable of predicting the failure mode and ultimate pullout capacity of the suction anchor in clay under inclined loading is developed. This method is based on a rational mechanical model for suction anchors and the knowledge of the mechanism that the anchor fails in seabed soils. In order to examine the analytical model, the failure angle and pullout capacity of suction anchors from FEM simulation, numerical solution and laboratory tests in uniform and linear cohesive soils are employed to compare with the theoretical predictions and the agreement is satisfactory. An analytical method that can evaluate the optimal position of the attachment point is also proposed in the present study. The present work proves that the failure mode and pullout capacity of suction anchors can be reasonably determined by the developed analytical method.

• Journal of Microbiology and Biotechnology
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• v.27 no.2
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• pp.388-394
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• 2017

Although several analytical methods for measuring total antioxidant capacity (TAC) have been applied to biological samples, there were often dissimilar results due to the different principles of methods applied. Thus, this study aimed to validate four conventional analytical methods for measuring plasma TAC, including the ABTS assay, DPPH assay, FRAP assay, and ORAC assay, by comparing with urinary 8-isoprostane concentration. In addition, TAC results were compared with antioxidant enzyme activities including superoxide dismutase (SOD) and glutathione peroxidase in erythrocyte, and catalase in plasma. Plasma TAC measure by ABTS assay was strongly correlated with the result by FRAP assay. Plasma TAC by FRAP and ORAC assays were negatively correlated with erythrocyte SOD activity. The agreement among the four TAC assay methods and 8-isoprostane was determined using 95% prediction limits of linear regression, expressed as the mean of 8-isoprostane ${\pm}95%$ prediction limits. The ABTS method better agreed with 8-isoprostane than the other methods, demonstrating narrow prediction of limits. Furthermore, only plasma TAC determined by the ABTS assay was inversely correlated with urinary 8-isoprostane (r = -0.35, p < 0.05). In summary, the ABTS assay would be an appropriate method to measure overall plasma antioxidant capacity and predict the body's antioxidant status.

• Geomechanics and Engineering
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• v.30 no.1
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• pp.11-26
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• 2022

One of the most important issues in tunneling, is the squeezing phenomenon. Squeezing can occur during excavation or after the construction of tunnels, which in both cases could lead to significant damages. Therefore, it is important to predict the squeezing and consider it in the early design stage of tunnel construction. Different empirical, semi-empirical and theoretical-analytical methods have been presented to determine the squeezing. Therefore, it is necessary to examine the ability of each of these methods and identify the best method among them. In this study, squeezing in a part of the Alborz service tunnel in Iran was estimated through a number of empirical, semi- empirical and theoretical-analytical methods. Among these methods, the most robust model was used to obtain a database including 300 data for training and 33 data for testing in order to develop a machine learning (ML) method. To this end, three ML models of Gaussian process regression (GPR), artificial neural network (ANN) and support vector regression (SVR) were trained and tested to propose a robust model to predict the squeezing phenomenon. A comparative analysis between the conventional and the ML methods utilized in this study showed that, the GPR model is the most robust model in the prediction of squeezing phenomenon. The sensitivity analysis of the input parameters using the mutual information test (MIT) method showed that, the most sensitive parameter on the squeezing phenomenon is the tangential strain (ε_θ^α) parameter with a sensitivity score of 2.18. Finally, the GPR model was recommended to predict the squeezing phenomenon in tunneling projects. This work's significance is that it can provide a good estimation of the squeezing phenomenon in tunneling projects, based on which geotechnical engineers can take the necessary actions to deal with it in the pre-construction designs.

• BMB Reports
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• v.45 no.6
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• pp.323-330
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• 2012

The glycome consists of all glycans (or carbohydrates) within a biological system, and modulates a wide range of important biological activities, from protein folding to cellular communications. The mining of the glycome for disease markers represents a new paradigm for biomarker discovery; however, this effort is severely complicated by the vast complexity and structural diversity of glycans. This review summarizes recent developments in analytical technology and methodology as applied to the fields of glycomics and glycoproteomics. Mass spectrometric strategies for glycan compositional profiling are described, as are potential refinements which allow structure-specific profiling. Analytical methods that can discern protein glycosylation at a specific site of modification are also discussed in detail. Biomarker discovery applications are shown at each level of analysis, highlighting the key role that glycoscience can play in helping scientists understand disease biology.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2004.10a
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• pp.503-510
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• 2004

One of the methods improving the seismic behavior of a structure is the frame with reduced beam section (RBS) which cuts a segment of flanges of the beam near the beam-to-column connection so that the section with reduced flanges has smaller flexural strength than the beam end. It is difficult to analyze the RBS frame because RBS portion has circular-cut type flange. And inelastic response of the steel frame with the RBS is very sensitive to the RBS model. In this paper, the analytical models of RBS portion are investigated and the results of the inelastic analysis for RBS analytical models are compared and then the analytical model for RBS is determined based on the results of inelastic analysis. Inelastic behavior of the RBS frame and its dynamic characteristics are investigated for selected analytical model of RBS.