• 한국수자원학회논문집
• /
• 제41권3호
• /
• pp.315-324
• /
• 2008

본 연구는 조건부가치평가법 중 이중양분선택형 질문을 사용하여 안양천 유역의 수질개선에 대한 지불의사를 추정하였다. 선형로짓모형에서 전체 응답자의 지불의사액은 4,930원이었으며 서울지역 거주민과 경기지역 거주민의 차이는 없는 것으로 추정되었다. 응답자들은 전반적으로 조건부 시장을 잘 받아들였으며 가구당 월평균 3,860원에서 5,101원의 지불의사를 가지고 있는 것으로 분석되었다. 이 값을 전체지역으로 확장하면 연간 약 83.0억원에서 109.7억원에 해당한다. 본 연구는 정책결정자들이 향후 유역과 관련된 사업에서 의사결정과정에 유용한 연구과정과 정량적인 정보를 제공할 것으로 기대한다.

• Animal Bioscience
• /
• 제34권8호
• /
• pp.1253-1270
• /
• 2021

Assessment of male fertility is based on the evaluation of sperm. Semen evaluation measures various sperm quality parameters as fertility indicators. However, semen evaluation has limitations, and it requires the advancement and application of strict quality control methods to interpret the results. This article reviews the recent advances in evaluating various sperm-specific quality characteristics and methodologies, with the help of different assays to assess sperm-fertility status. Sperm evaluation methods that include conventional microscopic methods, computer-assisted sperm analyzers (CASA), and flow cytometric analysis, provide precise information related to sperm morphology and function. Moreover, profiling fertility-related biomarkers in sperm or seminal plasma can be helpful in predicting fertility. Identification of different sperm proteins and diagnosis of DNA damage has positively contributed to the existing pool of knowledge about sperm physiology and molecular anomalies associated with different infertility issues in males. Advances in methods and sperm-specific evaluation has subsequently resulted in a better understanding of sperm biology that has improved the diagnosis and clinical management of male factor infertility. Accurate sperm evaluation is of paramount importance in the application of artificial insemination and assisted reproductive technology. However, no single test can precisely determine fertility; the selection of an appropriate test or a set of tests and parameters is required to accurately determine the fertility of specific animal species. Therefore, a need to further calibrate the CASA and advance the gene expression tests is recommended for faster and field-level applications.

• 사상체질의학회지
• /
• 제34권2호
• /
• pp.48-64
• /
• 2022

Objectives The purpose of this study was to review and evaluate the clinical evidence of the efficacy and safety of treatment based on Sasang constitutional medicine (SCM) for post-stroke patients by systematic review and meta-analysis. Methods Randomized controlled trials (RCTs), published in 10 electronic databases up to December 2020, were searched. For the included studies, Cochrane's risk of bias assessment was performed to analyze the methodological quality. The strength of evidence was evaluated using the grading of recommendations assessment, development, and evaluation system based on the results of analyses. All review processes were performed by two independent researchers. Results Five RCTs were finally included. All included RCTs were conducted for one month on post-stroke patients in 60-80s, four studies on Tae-Eum patients and one study on So-Yang patients. Four types of constitution-specific herbal medicine (Chungpyesagan-tang, Cheongsimsanyak-tang, Yeoldahanso-tang, and Yangkyuksanhwa-tang) and constitution-specific acupuncture therapy were identified as interventions. More than half of the included studies were evaluated as low quality due to the high-risk of bias in selection, performance, and detection. The combination of constitution-specific herbal medicine, acupuncture, and conventional treatment was more effective in improving the patients' motor impairment, dysphagia, aphasia, and depression than conventional treatment alone. No serious adverse events by SCM treatment were reported. Conclusions SCM treatment may improve the sequelae of post-stroke patients safely in combination with conventional treatment. Since the quality of clinical evidence included in this study was low, higher quality clinical evidence obtained in well-designed clinical studies will be needed.

• 한국조리학회지
• /
• 제15권3호
• /
• pp.356-372
• /
• 2009

본 연구에서는 국내 식품, 조리, 외식, 관광 관련 대표 학술지에 게재된 한식당의 서비스 품질 관련 논문 분석을 통해서 한식당 서비스 품질 연구의 학문적 경향을 고찰하고자 하였다. 연구 결과, 선정된 7개의 학술지에 게재된 한식당 서비스 품질 관련 연구는 2000~2008년 동안 총 26편이었으며, 그 중 100석 이상 규모의 중 대형 전문한식당을 대상으로 한 연구가 14편을 차지하였다. 방법론적인 측면에서 한식당의 서비스 품질 측정에 가장 빈번하게 사용된 척도는 Parasuraman et al.(1988)의 SERVQUAL, Stevens et al.(1995)의 DINESERV, Brady & Cronin(2001) 등의 척도로 나타났다. 내용적인 측면에서 한식당의 서비스 품질과 관련된 연구 동향을 고찰한 결과, 고객의 인지된 서비스 품질 중 직원과 고객 간의 상호작용 품질이 물리적 품질이나 전문적 품질보다 고객의 행동 반응에 더 큰 영향력을 지니는 것으로 조사되었다. 이러한 결과를 통해, 한식당 서비스 품질 고찰을 통한 제도적 연구를 위해서는 체계적으로 검증된 척도로써 고객의 인지된 서비스 품질을 파악하는 것이 우선적으로 시행되어야 하며, 연구 방법론에 있어서도 다양성을 모색하고, 연구 주제에 적합한 연구 방법을 시도해야 할 것으로 판단된다. 또한, 국내 한식당 서비스 품질과 관련된 대부분의 연구들이 고객의 인지된 서비스 품질과 만족도, 행동 의도의 인과관계 고찰과 같은 특정 주제에 집중된 경향을 보이고 있었으므로, 이러한 경향에서 벗어나기 위해서는 창의적인 연구 주제를 발굴하고 다양하고 과학적인 분석방법을 설계하는 것이 필요할 것으로 여겨진다.

• Journal of Acupuncture Research
• /
• 제28권6호
• /
• pp.1-17
• /
• 2011

Objectives : This study aimed to review randomized controlled trials of acupuncture performed in South Korea that used sham acupuncture as a control group. Methods : The following databases were searched through the end of September 2011: Koreanstudies information service system (KISS), Korean medical database (KMbase), national discovery OR science leaders (NDSL), oriental medicine advance searching integrated system (OASIS), and research information service system (RISS). The following search terms were used: acupuncture AND (sham or placebo). The reference lists of searched articles and Korea institute of oriental medicine (KIOM) reports(2005~2009) were identified. The following data were extracted: year/first author, disease, number of participants, blinding, intervention, outcome, and result. Where appropriate, we performed meta-analysis. The methodological quality was assessed according to the Jadad scale and 'risk of bias' by Cochrane Handbook procedure. Results : Twenty-nine studies were included in this review. In eighteen studies, penetrating sham controls were used as the control intervention, whereas the remaining eleven studies adopted non-penetrating sham controls such as the Park Sham Device or blunt auricular acupuncture. Nine studies showed statistically significant difference in outcomes. Twelve studies concerning insomnia after stroke, chronic tension-type headache, idiopathic Parkinson's disease, Hwa-Byung, and smoking cessation were included in meta-analysis. A meta-analysis of insomnia after stroke only found significant difference(MD -4.31, 95% Cl -6.19 to -2.42, $p$<0.00001). In general, all of the studies showed low methodological quality(Jadad score: mean 2.1). Risk of bias by Cochrane Handbook procedure varied. Conclusions : The results of this study could not suggest conclusive evidence that acupuncture is more effective than sham acupuncture in several diseases. In the future, more studies with rigorous acupuncture trials using sham controls should be conducted.

• 동의신경정신과학회지
• /
• 제34권3호
• /
• pp.259-274
• /
• 2023

Objectives: The purpose of this study was to provide clinical evidence to support the use of auricular blood-letting therapy (ABT) for headaches. Methods: Studies were identified by a comprehensive search of five databases. Randomized controlled trials (RCTs) that investigated the effects of the ABT for headaches were included. Two authors independently extracted the data and assessed the methodological quality of the included studies using Cochrane's risk-of-bias tool. If two or more studies reported the same outcome, a meta-analysis was performed. Meta-analysis results for dichotomous variables are expressed as risk ratios (RRs) and 95% confidence intervals (CIs). Results: A total of eight RCTs were included in this review. The total effective rate (TER) was the most commonly used outcome measurement. Among the eight RCTs, five were included in the metaanalysis. The TER was not statistically significantly different in the ABT group compared to the medication group (two studies, n=55, RR=1.24, 95% CI: 0.78 to 1.96, p=0.36, I² =86%). However, the TER of the combined ABT and medication group was significantly different compared to the medication alone group (four studies, n=159, RR=1.23, 95% CI: 1.12 to 1.35, p<0.0001, I² = 0%). Pain and mental health-related outcomes in the combined ABT and medication group were significantly different from the control groups. The methodological quality of the included RCTs was generally low. Conclusions: ABT combined with medication may be effective for treating headaches. However, the number of studies included was small, so the results were insufficient, and statistically significant effects were not confirmed for a single implementation of ABT. Thus, well-designed further studies based on the findings of this study are recommended.

• 재활치료과학
• /
• 제12권2호
• /
• pp.25-42
• /
• 2023

목적 : 본 연구에서는 뇌성마비 아동을 대상으로 작업치료 중재를 시행한 국내 단일대상연구들의 연구 특성을 종합적으로 분석하고 방법론적 질적 수준을 확인하여 근거 기반을 위한 기초자료를 제공하고자 하였다. 연구방법 : 본 연구는 2022년 5월 20일부터 29일까지 Research Information Sharing Service (RISS), National Digital Science Library (NDSL), Koreanstudies Information Service System (KISS), E-article에 게재된 문헌들을 대상으로 하였다. 검색어는'뇌성마비' AND '단일대상연구' OR '개별대상연구'였다. 11편의 논문을 최종 선택하여 일반적 특성과 방법론적 질적 수준을 분석하였다. 결과 : 11편의 분석 논문에서 방법론적 질적 수준은 중간 수준인 연구가 가장 많았다. 대상자는 학령전기 아동과 경직성 편마비 아동이 가장 많았고, 실험설계는 단일대상연구 설계에서 중재 제거 설계가 가장 많았으며 그 중에서 ABA 설계가 가장 많았다. 중재의 종류는 보조기기, 강제유도치료, 신경발달치료 접근, 감각통합치료가 각각 2편이었고, 상지운동훈련, 상호작용 메트로놈, 인지 기반 작업수행이 각각 1편이었다. 측정 도구는 최소 2개에서 최대 4개를 사용하여 종속변인을 측정하였고, 자세조절능력, 보행 및 균형, 손기능, 상지기능 등에서 긍정적인 효과 및 유의한 향상이 나타났다. 결론 : 본 연구는 작업치료 중재를 적용한 뇌성마비 대상자의 특성과 중재 회기 및 시간, 중재효과, 측정도구와 방법론적 질적 수준을 제시함으로써 뇌성마비를 대상으로 작업치료 중재를 적용할 때 도움이 될 것으로 확인된다.

• 한방재활의학과학회지
• /
• 제33권3호
• /
• pp.135-148
• /
• 2023

Objectives To investigate the effectiveness of acupuncture in the treatment of post-disaster musculoskeletal pain by reviewing relevant clinical studies. Methods A systematic search was conducted across 10 electronic databases to identify relevant clinical studies on acupuncture treatment for post-disaster musculoskeletal pain until May 2023. The methodological quality was evaluated using the Cochrane Risk of Bias 2 and Risk of Bias Assessment tool for non-randomized studies tools. Results Six articles were analyzed, including two randomized controlled trials (RCTs), two before-after studies, one qualitative research, and one case series. Overall, acupuncture therapy showed some improvement in pain scale among musculoskeletal pain survivors. However, no significant improvement was observed in the Short-Form McGill Pain Questionnaire (SF-MPQ-2). Subgroup analysis of participants who completed at least four acupuncture sessions revealed a significant effect on the SFMPQ-2. Additionally, a significant improvement in 36-Item Short Form Survey (SF36P) was observed after 6 months of treatment, but the 2-month treatment period did not show statistically significant effects on SF-36P improvement. The evaluation of the methodological quality of the RCTs identified some concerns of bias. Conclusions The results suggest that acupuncture is effective in alleviating post-disaster musculoskeletal pain. However, considering the limited number of selected studies and the inclusion of subjective evaluation measures, caution should be exercised in interpreting the results. Further large-scale follow-up studies are needed to determine the optimal frequency and duration of acupuncture treatment. Well-designed controlled trials should be conducted to provide more robust evidence regarding the effectiveness of acupuncture for post-disaster musculoskeletal pain.

• 대한한방내과학회지
• /
• 제33권4호
• /
• pp.448-464
• /
• 2012

Objectives : This study reviews the latest articles in Korea and other countries that studied oriental medicine treatment on poststroke depression. Methods : Korean articles were retrieved from the 9 major Korean web article search engines. Foreign articles were retrieved from PubMed. Article published date was from 2000 up to September 2012. There were no restrictions on the types of publication, but articles not available in full text were excluded. The methodological quality was assessed according to Cochrane's assessment of risk of bias and Newcastle-Ottawa quality assessment scale. Results : Twenty-two articles were included in this study. Eleven articles were published in Korea, the rest were published in China. Nine articles were randomized controlled trials (RCT), one article was a non-randomized study (NRS), four articles were case reports, three articles were cross-sectional studies, two articles were comparative studies. In RCT articles, risk of selection bias and performance bias were generally high, risk of detection bias was unclear. The NRS article took four stars in Newcastle-Ottawa quality assessment. Comparison Hamilton rating scale for depression score between oriental medicine treated group and western medicine treated group revealed that there was no remarkable difference in mean score changes after treatment on PSD. Conclusions : The results of this study suggest that oriental medicine treatment is as effective as western medicine treatment for PSD. In the future, more rigorous oriental medicine treatment studies should be conducted.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권19호
• /
• pp.8361-8366
• /
• 2014

This meta-analysis was performed to assess the implementation effects of clinical pathways in patients with gastrointestinal cancer. A comprehensive search was conducted in the Cochrane Library, PubMed, EMBASE, Web of Science and Chinese Biomedical Literature Database (from inception to May 2014). Selection of studies, assessing risk of bias and extracting data were performed by two reviewers independently. Outcomes were analyzed by fixed-effects and random-effects model meta-analysis and reported as mean difference (MD), standardized mean difference (SMD) and odds ratio (OR) with 95% confidence intervals (CI). The Jadad methodological approach was used to assess the quality of included studies and the meta-analysis was conducted with RevMan 5.1 software. Nine citations (eight trials) involving 642 patients were included. The aggregate results showed that a shorter average length of stay [MD = -4.0; 95% CI (-5.1, -2.8); P < 0.00001] was observed with the clinical pathways as compared with the usual care. A reduction in inpatient expenditure [SMD = -1.5; 95% CI (-2.3, -0.7); P = 0.0001] was also associated with clinical pathways, along with higher patient satisfaction [OR = 4.9; 95% CI (2.2, 10.6); P < 0.0001]. Clinical pathways could improve the quality of care in patients with gastrointestinal cancer, as evidenced by a significant reduction in average length of stay, a decrease in inpatient expenditure and an improvement in patient satisfaction. Therefore, indicators and mechanisms within clinical pathways should be a focus in the future.