Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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Effectiveness of Auricular Blood-letting Therapy for Headaches: A Systematic Review and Meta-Analysis

두통에 대한 이혈 방혈요법의 유효성 분석: 체계적 문헌고찰 및 메타분석

  • Kyoungeun Lee (Dong-eui University Korean Medicine Hospital) ;
  • Min-Ryeong Park (Department of Korean Medicine, Dong-Eui University College of Korean Medicine) ;
  • Ji-Won Lee (Department of Korean Medicine, Dong-Eui University College of Korean Medicine) ;
  • In-Jun Hwang (Department of Korean Medicine, Dong-Eui University College of Korean Medicine) ;
  • Boram Lee (KM Science Research Division, Korea Institute of Oriental Medicine) ;
  • Jong Cheol Seo (Department of Acupuncture and Moxibustion, Dong-Eui University College of Korean Medicine) ;
  • Chan-Young Kwon (Department of Oriental Neuropsychiatry, Dong-Eui University College of Korean Medicine)
  • 이경은 (동의대학교부속한방병원) ;
  • 박민령 (동의대학교 한의과대학 한의학과) ;
  • 이지원 (동의대학교 한의과대학 한의학과) ;
  • 황인준 (동의대학교 한의과대학 한의학과) ;
  • 이보람 (한국한의학연구원 한의과학연구부) ;
  • 서종철 (동의대학교 한의과대학 침구학교실) ;
  • 권찬영 (동의대학교 한의과대학 한방신경정신과학교실)
  • Received : 2023.08.31
  • Accepted : 2023.09.18
  • Published : 2023.09.30
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Abstract

Objectives: The purpose of this study was to provide clinical evidence to support the use of auricular blood-letting therapy (ABT) for headaches. Methods: Studies were identified by a comprehensive search of five databases. Randomized controlled trials (RCTs) that investigated the effects of the ABT for headaches were included. Two authors independently extracted the data and assessed the methodological quality of the included studies using Cochrane's risk-of-bias tool. If two or more studies reported the same outcome, a meta-analysis was performed. Meta-analysis results for dichotomous variables are expressed as risk ratios (RRs) and 95% confidence intervals (CIs). Results: A total of eight RCTs were included in this review. The total effective rate (TER) was the most commonly used outcome measurement. Among the eight RCTs, five were included in the metaanalysis. The TER was not statistically significantly different in the ABT group compared to the medication group (two studies, n=55, RR=1.24, 95% CI: 0.78 to 1.96, p=0.36, I2 =86%). However, the TER of the combined ABT and medication group was significantly different compared to the medication alone group (four studies, n=159, RR=1.23, 95% CI: 1.12 to 1.35, p<0.0001, I2 = 0%). Pain and mental health-related outcomes in the combined ABT and medication group were significantly different from the control groups. The methodological quality of the included RCTs was generally low. Conclusions: ABT combined with medication may be effective for treating headaches. However, the number of studies included was small, so the results were insufficient, and statistically significant effects were not confirmed for a single implementation of ABT. Thus, well-designed further studies based on the findings of this study are recommended.

Keywords

Acknowledgement

This research was supported by the MSIT (Ministry of Science and ICT), Korea, under the Grand Information Technology Research Center support program (IITP-2023-2020-0-01791) supervised by the IITP (Institute for Information & communications Technology Planning & evaluation).

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