• 공업화학
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• 제17권2호
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• pp.217-222
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• 2006

폴리이미드는 높은 열안정성, 우수한 기계적, 전기적 성질을 가지고 있어 많은 연구가 진행되어 왔지만, 대부분의 유기용매에 불용인 관계로 그 용도가 제한되어 있다. 본 연구에서는 방향족 디아민인 2,2,-bis(3-amino-4-hydroxyphenyl) hexafluoropropane (BAPAF)와 3,3,-diamino-4,4- dihydroxybyphenyl (HAB)를 사용하고 방향족 디안하이드라이드인 4,4-(hexafluoroisopropylidene)diphthalic dianhydride (6FDA), pyromellitic dianhydride (PMDA), 4,4-oxydiphthalic dianhydride (OPDA), 3,3,4,4-benzophenone tetracarboxylic dianhydride (BTDA) 및 3,3,4,4-diphenylsulfone tetracarboxylic dianhydride (DSDA)를 사용하여 가용성 폴리이미드를 합성하였다. 폴리이미드의 성질은 NMR, FR-IR 및 TGA를 이용하여 조사하였으며, 유전상수는 축전용량을 측정하여 계산하였다. 히드록시기를 포함한 폴리이미드와 methacryloyl chloride를 반응시켜 감광성 폴리이미드를 합성하고, photolithography기술을 이용하여 micro-패턴을 형성하였다.

• Macromolecular Research
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• 제12권4호
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• pp.379-383
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• 2004

Poly(ethylene glycol)s (PEGs) are unique in their material properties, such as biocompatibility, non-toxicity, and water-solublizing ability, which are extremely useful for a variety of biomedical applications. In addition, a variety of functional PEGs with specific functionality at one or both chain ends have been synthesized for many specialized applications. Surface modifications using PEG have been demonstrated to decrease protein adsorption and platelet or cell adhesion on biomaterials. Furthermore, PEGs having anionic sulfonate terminal units have been proven to enhance the blood compatibility of materials, which has been demonstrated by the negative cilia concept. The preparation of telechelic PEGs having a sulfonic acid group at one end and a polymerizable methacryloyl group at the other is an interesting undertaking for providing macromers that can be used in various vinyl copolymerization and gel systems. In this paper, preliminary results on the synthesis and polymerization behavior of a novel PEG macromer is described with the aim of identifying a biocompatible material for applications in various blood-contacting devices.

• Journal of Periodontal and Implant Science
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• 제53권5호
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• pp.321-335
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• 2023

Purpose: The aim of this study was to investigate the efficacy of photo-crosslinked gelatin methacryloyl (GelMa) hydrogel containing calcium phosphate nanoparticles (CNp) when applying different fabrication methods for bone regeneration. Methods: Four circular defects were created in the calvaria of 10 rabbits. Each defect was randomly allocated to the following study groups: 1) the sham control group, 2) the GelMa group (defect filled with crosslinked GelMa hydrogel), 3) the CNp-GelMa group (GelMa hydrogel crosslinked with nanoparticles), and 4) the CNp+GelMa group (crosslinked GelMa loaded with nanoparticles). At 2, 4, and 8 weeks, samples were harvested, and histological and micro-computed tomography analyses were performed. Results: Histomorphometric analysis showed that the CNp-GelMa and CNp+GelMa groups at 2 weeks had significantly greater total augmented areas than the control group (P<0.05). The greatest new bone area was observed in the CNp-GelMa group, but without statistical significance (P>0.05). Crosslinked GelMa hydrogel with nanoparticles exhibited good biocompatibility with a minimal inflammatory reaction. Conclusions: There was no difference in the efficacy of bone regeneration according to the synthesized method of photo-crosslinked GelMa hydrogel with nanoparticles. However, these materials could remain within a bone defect up to 2 weeks and showed good biocompatibility with little inflammatory response. Further improvement in mechanical properties and resistance to enzymatic degradation would be needed for the clinical application.

• 대한화학회지
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• 제48권6호
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• pp.599-608
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• 2004

유연격자와 메타크릴로일 기 사이에 도입된 벤젠 고리와 메소겐 구조의 말단에 연결된 키랄 중심을 갖는 새로운 두 계열의 메타크릴레이트 단량체를 합성하였다. 이 두 계열에서 유연격자와 메소겐 기의 길이 변화에 따른 액정형성에 대한 효과를 조사하였다. 첫 번째 계열의 화합물들은 합성과정에서 얻어진 중간물질이나 최종물질에서 액정성을 보이지 않았다. 그러나 두 번째 계열에서는 중간물질 뿐만아니라 최종물질에서도 액정성을 보였다.

• 폴리머
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• 제35권5호
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• pp.409-418
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• 2011

A novel silicone (Si) containing vinylic monomer, N-(3-(triethoxysilyl)propyl) methacrylamide (TESPMA), based on 3-aminopropyltriethoxysilane (APTES) and methacryloyl chloride (MCl) has been synthesized for formulation of waterborne polyurethane (WPU). Two types of vinyl group containing Si, methacryloxypropyltriethoxysilane (MPTES) and triethoxyvinylsilane (TEVS), have been used as coupling reagents for comparison of the effects of Si kinds with TESPMA on the WPU. A series of new siliconized WPU, vinyl acetate/vinyl ester of versatic acid (VAc-Veova), TESPMA, MPTES and TEVS hybrid latexes have been successfully prepared by emulsion polymerization in the presence of WPU dispersion.

• 폴리머
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• 제32권2호
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• pp.189-192
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• 2008

Styrylpyrylium salt 화합물(DHSP)을 합성하고 광이량화시켜 cyclobutane형 이량체(DHSP dimer)를 합성하였다. 여기에 메타크릴레이트기를 도입하여 DMSP dimer를 합성하였다. DMSP dimer 광가교물의 FT-IR 분석 결과, 크랙 생성에 의해 cyclobutane환이 개열되어 styryl C=C 구조로 되돌아가는 것으로 판단되었다. 385 nm의 빛에 의하여 DHSP는 626 nm의 형광을 방출하는 반면 DHSP dimer는 매우 약한 형광만을 나타내었다. DMSP dimer의 광가교 필름에 microcrack을 생성시키고 $330{\sim}385\;nm$의 빛을 조사한 결과, 크랙 부분에서의 형광 방출이 확인되었다.