• 생물정신의학
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• 제14권2호
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• pp.122-128
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• 2007

Objectives : The aim of this study was to investigate relationships between psychotic symptoms and cognitive functions in schizophrenia. Methods : The study group was composed of 36 schizophrenic patients. Positive, negative, and disorganization symptoms were assessed using the PANSS. Verbal, visuospatial, attention, memory, and executive functions were assessed using a battery of cognitive tests. Results : Correlation analysis between symptom vs. cognitive measures showed that (a) positive symptoms were significantly correlated with no cognitive measures, (b) negative symptoms were significantly correlated with all cognitive measures, and (c) disorganization symptoms were significantly correlated with executive and memory measures. Correlation analyses between symptom vs. cognitive factors showed that negative-disorganization factor is significantly correlated with executive-memory factor. Conclusion : Significant relationships were confined mostly to frontal symptoms vs. frontal cognitive functions. Thus, the relationships may be mediated mainly by variations in severity of frontal pathology among patients.

• 한국의학물리학회지:의학물리
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• 제21권1호
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• pp.42-51
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• 2010

뇌 기능 연구 분야에서는 MRI, PET, MEG 영상 시스템 등을 이용한 인지기능에 대한 정량적 평가 연구가 계속적으로 이루어 지고 있다. 최근에는 컴퓨터 기술을 응용하여 인지 기능의 정량적 분석을 효과적으로 하고자 시도되고 있다. 본 연구에서는 터치 스크린을 이용하여 인지 기능의 정량적 평가를 할 수 있는 소프트웨어 패키지를 구현하였다. 여기서 구현된 내용은 집중력, 숫자 기억력, 조합 기억력, 위상 기억력, 시각 및 근육 반응, 청각 반응 등으로 되어 있다. 우리는 구현된 소프트웨어에 대하여 실험적 검증과정을 거치고자 20~59세까지의 연령 및 성별에 따른 80명을 대상으로 실험을 수행하였다. 남녀 모두 40세 이후의 연령에서 인지기능의 감쇄가 일어나는 결과를 정량적 획득하였다. 본 연구에서는 고가 장비인 영상 시스템뿐만 아니라 상대적으로 간소화된 소프트웨어를 이용하여서도 인지기능의 정량적 평가가 가능함을 보여주고 있다. 이러한 방법을 적용하여 다양한 그룹의 인지 기능의 정량적 평가 및 비교를 수행하는 데 비용과 시간을 줄일 수 있을 것으로 보인다.

• 한국산학기술학회논문지
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• 제21권9호
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• pp.358-372
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• 2020

본 연구는 성인의 인지예비능, 주관적 기억감퇴, 우울 및 삶의 질 등과 같은 요인들이 인지기능에 미치는 직·간접 효과를 규명하고자 하였다. 연구 대상자는 만 40세 이상 80세 미만의 성인 남녀 253명을 대상으로 설문 조사하였고, 본 연구에 사용된 도구는 인지기능 척도, 우울 척도, 삶의 질, 주관적 기억감퇴, 인지예비능 척도를 사용하였다. 데이터 결과는 SPSS 25.0를 이용하여 분석하였고, PROCESS macro for SPSS Version 3.3과 부트스트래핑 방법을 활용하였다. 연구결과, 성인의 인지예비능은 우울과 삶의 질에 영향을 미치는 것으로 나타났으며, 인지예비능과 인지기능의 다중 매개 결과는 우울 및 주관적 기억감퇴에서 매개효과가 나타나지 않았다. 그러나 삶의 질은 성인의 인지예비능과 주관적 인지기능 간의 관계에서 완전매개효과를 나타냈다. 본 연구결과를 토대로 성인들은 다양한 활동과 지속적인 훈련을 통해 인지예비능을 꾸준히 축적하여 인지기능이 긍정적인 방향으로 이어지도록 하는 것이 필요하다. 또한 건강한 성인들을 대상으로 한 인지예비능과 인지기능을 위한 많은 연구들이 실행되기를 제언한다.

• 한국엔터테인먼트산업학회논문지
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• 제13권6호
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• pp.277-286
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• 2019

본 연구의 목적은 전산화 인지재활과 전통적 인지훈련이 경도 외상성 뇌손상 환자의 작업기억과 실행기능에 미치는 영향을 탐색하기 위함이다. 본 연구는 재활병원에서 재활치료를 받는 경도 외상성 뇌손상 환자 20명이 참여하였다. 대상자들은 실험군 10명과 대조군 10명으로 할당되었다. 실험군은 전산화 인지재활과 전통적인 인지훈련을 30분씩 60분을 받았으며, 대조군은 전통적인 인지훈련을 60분 수행하였다. 두 군은 하루 60분, 주 5회, 4주 동안 배정된 훈련을 수행하였다. 작업기억과 실행기능을 평가하기 위하여, 숫자외우기 검사(정방향, 역방향)와 MVPT-3의 시각기억, 그리고 선추적 검사와 스트룹 검사 A와 B를 중재 전과 후에 실시하였다. 두 군 간 변화량 비교에서 실험군은 대조군보다 시각기억과 스트룹 검사 A에서 유의하게 더 큰 향상을 보였다. 이러한 결과는 전산화 인지재활과 전통적 인지훈련이 전통적인 인지훈련보다 작업기억과 실행기능에 긍정적인 변화를 제공할 수 있음을 시사한다.

• The Journal of Korean Physical Therapy
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• 제27권5호
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• pp.375-380
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• 2015

Purpose: The purpose of this study was to evaluate the impact of differences in computer-aided cognitive rehabilitation aimed at stroke patients on cognitive function and daily life. Methods: The study subjects were Gwangju, Jeonnam including the attention group (group I), memory group (group II), and visual perception group (group III), who were randomly placed in each of a 10 by one problem solving group (group IV). The PSSCogRehab was applied to all subjects who underwent eight weeks once a week after 20 minutes in each group by strengthening mediation 10 minutes 30 minutes total, with a five minute break in the middle. Results: Cognitive function and activities of daily living is security and inter-group differences before intervention, and post-test results in the memory training group II, the intervention group I, III, IV and more on cognitive function and activities of daily living compared to it was effective. Conclusion: The results of computer-aided cognitive rehabilitation measuring cognitive function and ADL in patients with stroke in accordance with the group I, III, and IV group cognitive function and activities of daily living compared to IV showed that it was more effective.

• 대한통합의학회지
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• 제12권1호
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• pp.83-96
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• 2024

Purpose : This study was conducted to determine the effects of a brain spinning program on cognitive function, body composition, health related fitness and physical self-efficacy of children and adolescents. Methods : This study, 34 children and adolescents were selected and divided into two groups : the exercise group (n=16), which received a brain spinning program and the control group (n=16), which did not receive any exercise program. The program was conducted for 30 minutes three times a week for 4 weeks, and the cognitive function, body composition, health related fitness and physical self-efficacy were measured both before and after the program. Results : The exercise group, which received a brain spinning program showed a significant increase in short-term memory (p<.05) and working memory (p<.01), and muscle mass increased significantly only in the exercise group (p<.05). In addition, left grip strength increased in the exercise group (p<.01), and the maximum oxygen intake decreased significantly only in the control group (p<.05), and Sit-forward bend increased significantly only in the exercise group (p<.01). Physical self-efficacy significantly increased only in the exercise group (p<.05). Conclusion : In summary, short-term memory, cognitive efficiency, working memory, muscle mass, left grip strength, maximum oxygen intake, and left forward bending in children and adolescents significantly increased after the 4-week brain spinning program. However, the control group that was not provided with the 4-week brain spinning program showed a significant increase in body weight and a significant decrease in maximum oxygen intake. In conclusion, the 4-week brain spinning program has positive effects on short-term memory, cognitive function, muscle mass, muscle strength, cardiorespiratory endurance, flexibility, and physical self-efficacy.

• 생물정신의학
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• 제23권4호
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• pp.199-204
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• 2016

Objectives Although forgetfulness is a common complaint among menopausal depressed women, there is still a debate about the relationship between memory impairment and menopause. The aim of this study is to examine whether menopause is related to cognitive decline among women with depressive disorders. We hypothesized that postmenopausal depressed women show generally poorer performance than premenopausal depressed women on various cognitive function tests. Methods With a retrospective chart review, we identified a total of 87 female patients (45 premenopausal patients and 42 postmenopausal patients) who were hospitalized with depressive disorders from 2000 to 2016. Demographic and clinical variables and cognitive test results were compared between two groups. Results Education year is longer in premenopausal group than postmenopausal group whereas clinical characteristics (illness duration, recurrence, and symptom severity) and mean Intelligence Quotient (IQ) were similar between two groups. The postmenopausal group took longer time for Bender-Gestalt Test (BGT) recall, Trail Making Test (TMT)-A, and TMT-B than the premenopausal group. After controlling for age and education, significant difference was remained for BGT recall (p = 0.029). Conclusions Postmenopausal state may be related with decline of visuospatial memory function, in particular, among depressed female patients. Other areas of cognitive function including complex attention, verbal memory, auditory memory, and working memory might be interpreted while considering age and education level.

• 국제물리치료학회지
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• 제9권4호
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• pp.1591-1595
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• 2018

The number of healthy older adults is rapidly increasing recently owing to the increase of the elderly population. Therefore, programs for improving the cognitive functions of these healthy seniors are actively being expanded. This study aimed to prevent the decline of cognitive function due to aging by applying a program enhancing cognitive functions to healthy older adults. The objective of this study was to evaluate the effects of Korean computer-based cognitive rehabilitation program (CoTras), which is commonly used in cognitive therapy for the aging, on the memory of the elderly. The subjects had scored at least 24 points in MMSE-K. CoTras was applied once a week (30 minutes) for one month. Electronic pegboard programs were used as an evaluation tool: order memory (difficulty=low) and location memory (difficulty=medium). The order and location memories were compared before and after the intervention. The Wilcoxon signed rank-sum test was used for the study at the significance level of ${\alpha}=.05$. The results showed that CoTras significantly improved order memory and location memory. Therefore, CoTras can be applied to the healthy elderly for improving that memory improvement training has a positive impact on healthy older adults result in the development of memory enhancement programs can be expanded in the future.

• 셀메드
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• 제13권14호
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• pp.14.1-14.9
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• 2023

Administration of Scopolamine can be considered a psychopharmacological model of Alzheimer's disease (AD). We made an animal model of Alzheimer's disease (AD) by administering Scopolamine to Blab/c mice. In this study, we investigated the effects of Resplex Alpha on memory impairment and cognitive function in mice in a mouse animal model of Scopolamine-induced memory impairment. Through Y-mazed and passive avoidance behavioral assays, we observed that Resplex Alpha recovered Scopolamine-induced short-term memory and cognitive functions. The results of our study imply that Resplex Alpha may be beneficial in the prevention of Alzheimer's disease (AD).

• International Journal of Internet, Broadcasting and Communication
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• 제14권3호
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• pp.230-242
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• 2022

The purpose of this study was to verify the effectiveness of the computerized cognitive rehabilitation program in which areas and to suggest effective ways to utilize the program in the future, being conducted for 20 college students. We lasted this study from May 3 to 23, 2021. As a result of analyzing the groups using the Computer-based Cognitive Rehabilitation Program (CoTras), in terms of the difference in accuracy for the case of visual perception group B was statistically significantly improved than group C(p<0.05). In the case of attention, memory, and orientation, there was no significant difference between groups(p>0.05). In the case of reaction time difference, there was no significant difference between groups in visual perception, concentration, memory, and orientation(p>0.05). And in order to improve attention and visual perception, it is recommended to conduct the program three times with a duration of 20 minutes, and in order to improve orientation and memory, it can be said that it is helpful to conduct one experiment for at least 30 minutes rather than conducting short and frequent experiments. Through this study, we found that it is effective to apply different times according to each area to improve cognitive function. In other words, depending on the purpose of which cognitive function is to be improved, the duration of the program should be applied differently.