• Title/Summary/Keyword: medical material

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Expression patterns of PRDM10 during mouse embryonic development

  • Park, Jin-Ah;Kim, Keun-Cheol
    • BMB Reports
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    • v.43 no.1
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    • pp.29-33
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    • 2010
  • It is well known that PR/SET family members participate in transcriptional regulation via chromatin remodeling. PRDM10 might play an essential role in gene expression, but no such evidence has been observed so far. To assess PRDM10 expression at various stages of mouse development, we performed immunohistochemistry using available PRDM10 antibody. Embryos were obtained from three distinct developmental stages. At E8.5, PRDM10 expression was concentrated in the mesodermal and neural crest populations. As embryogenesis proceeded further to E13.5, PRMD10 expression was mainly in mesoderm-derived tissues such as somites and neural crest-derived populations such as the facial skeleton. This expression pattern was consistently maintained to the fetal growth period E16.5 and adult mouse, suggesting that PRDM10 may function in tissue differentiation. Our study revealed that PRDM10 might be a transcriptional regulator for normal tissue differentiation during mouse embryonic development.

Study on Evaluation of Material Property of Micro Handpiece for dentistry and Surface Quality (치과용 시술기구(Micro Handpiece)재료의 특성평가 및 표면품질에 대한 연구)

  • Son, Jae-Hwan;Han, Chang-Woo;Choi, Sang-Il;Kim, Yong-Jung;Choi, Chang-Jin
    • Journal of the Korean Society of Industry Convergence
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    • v.9 no.3
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    • pp.221-228
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    • 2006
  • As Industrialization gets more and more advanced, human technological medical apparatus for dentistry has been developed. Such a medical apparatus have to let precision revolution and torque control facilitate. Consequently, Development of Micro hand-piece with strong durability should be required. Moreover, It's also very important to evaluate performance of such a Micro hand-piece, Evaluation of Mechanical property of Material and ANOVA have been known as useful methods in the field of Quality Evaluation. For Verification of Quality Evaluation, It has been evaluated by One-way layout ANOVA based on the data of Surface Roughness Test. Anyhow, This test has been respectively carried out by 3 kinds of Test and Superior performance has appeared in the Test result.

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Development of Multi-wavelength Laser Medical Therapy Apparatus (다파장 레이저치료기의 개발)

  • Cheon, Min-Woo;Kim, Seong-Hwan;Park, Yong-Pil;Lee, Ho-Sik;Kim, Tae-Gon
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.20 no.8
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    • pp.736-741
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    • 2007
  • Low level laser therapy has various therapy effects, This paper performed the basic study for fabricating the low level laser therapy apparatus, and one of the goals of this paper was to make this apparatus used handily. The apparatus has been fabricated using the laser diode and microprocessor unit. The apparatus used a 660nm, 785nm and 850nm laser diode for laser medical therapy and was designed for a pulse width modulation type to increase stimulation effects. To raise the stimulus effect of the human body, the optical irradiation frequency could be set up. In result, the $1{\sim}10\;Hz$ irradiation frequency could be controlled stably.

The Effect of LED Light Irradiation on Skin Injury Cure of Rat (LED 광원이 Rat의 피부 창상 치유에 미치는 영향)

  • Cheon, Min-Woo;Kim, Seong-Hwan;Park, Yong-Pil;Kim, Tae-Gon;Yu, Seong-Mi
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.20 no.12
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    • pp.1087-1092
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    • 2007
  • We developed the 4-channel Light Medical Therapy Apparatus for Skin Injury Cure using a high brightness LED. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity and reservation. In this paper, the designed device was used to find out how high brightness LED light affects the skin injury of SD-Rat(Sprague-Dawley Rat). In the experiment, $1\;cm^2$ wounds on the skin injury of SD-Rat(Sprague-Dawley Rat) were made. Light irradiation group and none light irradiation group divided, each group was irradiated one hour a day for 14 days. In result, compared with none light irradiation group, the lower incidence of inflammation and faster recovery was shown in light irradiation group.

A New Measurement Method of a Radial Pulse Wave Using Multiple Hall Array Devices

  • Lee, Sang-Suk;An, Myoung-Chone;Ahn, Sung-Hoon
    • Journal of Magnetics
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    • v.14 no.3
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    • pp.132-136
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    • 2009
  • This study investigated the radial pulse waveform obtained by a medical pulsimeter sensor. A pulse-sensing part array consisting of multiple Hall devices was located over a skin-contacting part with a hard magnetic material. The periodic movement of the magnetic material of the skin-contacting part affected the magnetic field in the pulse-sensing part array and was detected by multiple Hall devices. The analysis of a radial pulse waveform that is measured noninvasively by detecting the changes of the magnetic field can be used to develop a new diagnostic algorithm of oriental medical apparatus.

Development of Laser Diode Medical Therapy Apparatus for Blood Stream Improvement (혈류 개선용 레이저다이오드 치료기 개발)

  • Cheon, Min-Woo;Kim, Seong-Hwan;Park, Yong-Pil
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.06a
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    • pp.496-496
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    • 2007
  • Low level laser therapy has various therapy effects. This paper performed the basic study for fabricating the low level laser therapy apparatus, and one of the goals of this paper was to make this apparatus used handily. The apparatus has been fabricated using the laser diode and microprocessor unit. The apparatus used a 7850m Laser diode for blood stream improvement and was designed for a pulse width modulation type to increase stimulation effects. In result, we could get the light power of 785nm wavelength.

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Miniaturized meander-line dual-band implantable antenna for biotelemetry applications

  • Rajagopal Kangeyan;Madurakavi Karthikeyan
    • ETRI Journal
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    • v.46 no.3
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    • pp.413-420
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    • 2024
  • A dual-band bio-implantable compact antenna with a meander-line structure is presented. The proposed meander-line antenna resonates at the industrial, scientific, and medical (2.4 GHz) and wireless medical telemetry (1.4 GHz) bands. The meander-line structure is selected as a radiating patch given its versatile and effective design. With a dimension of only 10 mm × 10 mm × 0.635 mm, the designed antenna is compact. Considering a skin phantom, the proposed antenna was designed, optimized, and simulated. The Rogers RT/duroid 6010 substrate material with high dielectric constant was used to fabricate the meander-line dual-band implantable antenna, which was validated experimentally. The superstrate was made of the same material. Experiments were conducted on skin-mimicking gel. The designed meander-line antenna has a high peak gain of -21 dBi at 2.4 GHz, and its maximum specific absorption rate is compliant with IEEE safety standards.

The characteristic study of hybrid X-ray detector using CdTe and Zns:AgCl phosphor (CdTe 와 ZnS:AgCl phosphor를 이용한 Hybrid형 X선 검출기의 특성연구)

  • Seok, Dae-Woo;Kang, Sang-Sik;Kim, Jin-Young;Park, Ji-Koon;Mun, Chi-Woong;Nam, Sang-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.05c
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    • pp.71-74
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    • 2003
  • Photoconductor for direct detection fiat-panel imager present a great materials challenge, since their requirement include high X-ray absorption, ionization and charge collection, low leakage current and large area deposition, CdTe is practical material. We report studies of detector sensitivity, That is an CdTe with $5{\mu}m$ thickness on glass. That is hybrid layer of depositting ZnS:AgCl phosphor with $100{\mu}m$ on CdTe. The leakage current of hybrid is similar to it of a-Se, but photocurrent is larger than a-Se. Both of them have high spatial resolution, but hybrid has higher sensitivity than a-Se at comparable bias voltage.

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Image Quality of Amorphous Selenium DR system using MTF measurement (MTF 측정을 통한 비정질 셀레늄 기반의 디지털 방사선 검출기의 영상 질 평가에 관한 연구)

  • Seok, Dae-Woo;Park, Ji-Koon;Choi, Jang-Yong;Nam, Sang-Hee;Kang, Shin-Won
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.11a
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    • pp.384-387
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    • 2003
  • In this paper, the evaluation of image quality was performed for digital radiography which is developing in using amorphous selenium as a photoconductor material for the purpose of offering basic research data and measurement technique about Medical Imaging Quality. So Modulation Transfer Function as a main factor of imaging quality evaluation was investigated by slit method. For measurement of MTF, Nuclear associates. 07-624 Slit camera image was obtained to study the variation of MTF corresponding to changing spatial frequency. And Presampling MTF was estimated by slit camera image with $10\;{\mu}m$ width at Digital Radiography. In this study, the obtained data demonstrates that the clinical value of a direct conversion type digital radiation detector using the amorphous selenium, which is being developed by domestic technology.

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An Explainable Deep Learning-Based Classification Method for Facial Image Quality Assessment

  • Kuldeep Gurjar;Surjeet Kumar;Arnav Bhavsar;Kotiba Hamad;Yang-Sae Moon;Dae Ho Yoon
    • Journal of Information Processing Systems
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    • v.20 no.4
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    • pp.558-573
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    • 2024
  • Considering factors such as illumination, camera quality variations, and background-specific variations, identifying a face using a smartphone-based facial image capture application is challenging. Face Image Quality Assessment refers to the process of taking a face image as input and producing some form of "quality" estimate as an output. Typically, quality assessment techniques use deep learning methods to categorize images. The models used in deep learning are shown as black boxes. This raises the question of the trustworthiness of the models. Several explainability techniques have gained importance in building this trust. Explainability techniques provide visual evidence of the active regions within an image on which the deep learning model makes a prediction. Here, we developed a technique for reliable prediction of facial images before medical analysis and security operations. A combination of gradient-weighted class activation mapping and local interpretable model-agnostic explanations were used to explain the model. This approach has been implemented in the preselection of facial images for skin feature extraction, which is important in critical medical science applications. We demonstrate that the use of combined explanations provides better visual explanations for the model, where both the saliency map and perturbation-based explainability techniques verify predictions.