• 한국멀티미디어학회논문지
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• 제22권11호
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• pp.1269-1279
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• 2019

In medical image analysis, segmentation is considered as a vital process since it partitions an image into coherent parts and extracts interesting objects from the image. In this paper, we consider automatic segmentations of OCT retinal images to find six layer boundaries using convolutional neural networks. Segmenting retinal images by layer boundaries is very important in diagnosing and predicting progress of eye diseases including diabetic retinopathy, glaucoma, and AMD (age-related macular degeneration). We applied well-known CNN architecture for general image segmentation, called Segnet, U-net, and CNN-S into this problem. We also proposed a shortest path-based algorithm for finding the layer boundaries from the outputs of Segnet and U-net. We analysed their performance on public OCT image data set. The experimental results show that the Segnet combined with the proposed shortest path-based boundary finding algorithm outperforms other two networks.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2012년도 추계학술대회
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• pp.874-877
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• 2012

This paper proposes the new method based on contour following method with directional angle to segment the cell into the nuclei. The object image was the Thyroid Gland cell image that was diagnosed as normal and abnormal(two types of abnormal : follicular neoplastic cell, and papillary neoplastic cell), respectively. The nuclei were successfully diagnosed as normal and abnormal. this paper, improved method of digital image analysis required in basic medical science for diagnosis of cells was proposed. The object image was the Thyroid Gland cell image with difference of chromatin patterns. To segment the cell nucleus from background, the region segmentation algorithm by edge tracing was proposed. And feature parameter was obtained from discrete Fourier transformation of image. After construct a feature sample group of each cells, experiment of discrimination was executed with any verification cells. As a result of experiment using features proposed in this paper, get a better segmentation rate(70-90%) than previously reported papers, and this method give shape to get objectivity and fixed quantity in diagnosis of cells. The methods described in this paper be used immediately for discrimination of neoplastic cells.

• Korean Journal of Radiology
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• 제21권1호
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• pp.88-100
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• 2020

Objective: We aimed to develop and validate a deep learning system for fully automated segmentation of abdominal muscle and fat areas on computed tomography (CT) images. Materials and Methods: A fully convolutional network-based segmentation system was developed using a training dataset of 883 CT scans from 467 subjects. Axial CT images obtained at the inferior endplate level of the 3rd lumbar vertebra were used for the analysis. Manually drawn segmentation maps of the skeletal muscle, visceral fat, and subcutaneous fat were created to serve as ground truth data. The performance of the fully convolutional network-based segmentation system was evaluated using the Dice similarity coefficient and cross-sectional area error, for both a separate internal validation dataset (426 CT scans from 308 subjects) and an external validation dataset (171 CT scans from 171 subjects from two outside hospitals). Results: The mean Dice similarity coefficients for muscle, subcutaneous fat, and visceral fat were high for both the internal (0.96, 0.97, and 0.97, respectively) and external (0.97, 0.97, and 0.97, respectively) validation datasets, while the mean cross-sectional area errors for muscle, subcutaneous fat, and visceral fat were low for both internal (2.1%, 3.8%, and 1.8%, respectively) and external (2.7%, 4.6%, and 2.3%, respectively) validation datasets. Conclusion: The fully convolutional network-based segmentation system exhibited high performance and accuracy in the automatic segmentation of abdominal muscle and fat on CT images.

• 스마트미디어저널
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• 제9권3호
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• pp.59-70
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• 2020

This paper presents a fully automatic tool to recognize the liver region from CT images based on a deep learning model, namely Multiple Filter U-net, MFUnet. The advantages of both U-net and Multiple Filters were utilized to construct an autoencoder model, called MFUnet for segmenting the liver region from computed tomograph. The MFUnet architecture includes the autoencoding model which is used for regenerating the liver region, the backbone model for extracting features which is trained on ImageNet, and the predicting model used for liver segmentation. The LiTS dataset and Chaos dataset were used for the evaluation of our research. This result shows that the integration of Multiple Filter to U-net improves the performance of liver segmentation and it opens up many research directions in medical imaging processing field.

• 대한의용생체공학회:의공학회지
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• 제22권3호
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• pp.231-239
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• 2001

This paper proposes a region segmenting method for the Pap-smear image. The proposed method uses a pixel classifier based on neural network, which consists of four stages : preprocessing, feature extraction, region segmentation and postprocessing. In the preprocessing stage, brightness value is normalized by histogram stretching. In the feature extraction stage, total 36 features are extracted from $3{\times}3$ or $5{\times}5$ window. In the region segmentation stage, each pixel which is associated with 36 features, is classified into 3 groups : nucleus, cytoplasm and background. The backpropagation network is used for classification. In the postprocessing stage, the pixel, which have been rejected by the above classifier, are re-classified by the relaxation algorithm. It has been shown experimentally that the proposed method finds the nucleus region accurately and it can find the cytoplasm region too.

• 대한의용생체공학회:의공학회지
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• 제28권6호
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• pp.791-797
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• 2007

This paper proposes a semiautomatic vertebra segmentation method that overcomes limitations of both manual segmentation requiring tedious user interactions and fully automatic segmentation that is sensitive to initial conditions. The proposed method extracts fence surfaces between vertebrae, and segments a vertebra using fence-limited region growing. A fence surface is generated by a deformable model utilizing valley information in a valley emphasized Gaussian image. Fence-limited region growing segments a vertebra using gray value homogeneity and fence surfaces acting as barriers. The proposed method has been applied to ten patient data sets, and produced promising results accurately and efficiently with minimal user interaction.

• 한국멀티미디어학회논문지
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• 제17권12호
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• pp.1412-1417
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• 2014

The corpus callosum is the largest part of the brain, which is related to many neurological diseases. Snake model or active contour model is widely used in medical image processing field, especially image segmentation they look into the nearby edge, localizing them accurately. In this paper, corpus callosum segmentation using the snake model, is proposed. We tested a snake model on brain MRI. Then we compared the result with an active shape approach and found that snake model had better segmentation accuracy also faster than active shape approach.

• 대한의용생체공학회:의공학회지
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• 제20권2호
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• pp.149-154
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• 1999

자기공명영상은 다른 의료영상에 비해서 보다 정확한 해부학적인 진단 정보를 제공해 주므로 널리 이용되고 있다. 본 논문에서는 이차원 축단면 뇌 자기총명영상을 분할하는 자동화 알고리즘과 병별에 의해서 손상된 슬라이스를 검출하는 알고리즘을 제안하였다. 영상분활 과정은 두단계로 구성되어 있는데, 첫 단계에서는 이진화와 형태학적 연산을 이용하여 대뇌영역을 추출하고, 둘째 단계에서는 FCM(Fuzzy C-means)알고리즘을 이용하여 추출된 대뇌 내부의 각 조직을 분할하였다. FCM알고리즘은 분할하는 조직의 수가 증가할수록 급격하게 많은 실행시간을 요구하므로 제안하는 두단계 영상분할 과정을 통하여 실행시간을 향상시켰다. 병변 인식은 해부학적지식과 패턴매칭을 이용하였다.

• International Journal of Computer Science & Network Security
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• 제23권5호
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• pp.53-64
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• 2023

Early detection of endometrial carcinoma in uterus is essential for effective treatment. Endometrial carcinoma is the worst kind of endometrium cancer among the others since it is considerably more likely to affect the additional parts of the body if not detected and treated early. Non-invasive medical computer vision, also known as medical image processing, is becoming increasingly essential in the clinical diagnosis of various diseases. Such techniques provide a tool for automatic image processing, allowing for an accurate and timely assessment of the lesion. One of the most difficult aspects of developing an effective automatic categorization system is the absence of huge datasets. Using image processing and deep learning, this article presented an artificial endometrium cancer diagnosis system. The processes in this study include gathering a dermoscopy images from the database, preprocessing, segmentation using hybrid Fuzzy C-Means (FCM) and optimizing the weights using the Whale Optimization Algorithm (WOA). The characteristics of the damaged endometrium cells are retrieved using the feature extraction approach after the Magnetic Resonance pictures have been segmented. The collected characteristics are classified using a deep learning-based methodology called Long Short-Term Memory (LSTM) and Bi-directional LSTM classifiers. After using the publicly accessible data set, suggested classifiers obtain an accuracy of 97% and segmentation accuracy of 93%.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권10호
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• pp.2788-2808
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• 2023

Brain tumors are one of the most threatening malignancies for humans. Misdiagnosis of brain tumors can result in false medical intervention, which ultimately reduces a patient's chance of survival. Manual identification and segmentation of brain tumors from Magnetic Resonance Imaging (MRI) scans can be difficult and error-prone because of the great range of tumor tissues that exist in various individuals and the similarity of normal tissues. To overcome this limitation, the Amended Convolutional Neural Network (ACNN) model has been introduced, a unique combination of three techniques that have not been previously explored for brain tumor detection. The three techniques integrated into the ACNN model are image tissue preprocessing using the Kalman Bucy Smoothing Filter to remove noisy pixels from the input, image tissue segmentation using the Isotonic Regressive Image Tissue Segmentation Process, and feature extraction using the Marr Wavelet Transformation. The extracted features are compared with the testing features using a sigmoid activation function in the output layer. The experimental findings show that the suggested model outperforms existing techniques concerning accuracy, precision, sensitivity, dice score, Jaccard index, specificity, Positive Predictive Value, Hausdorff distance, recall, and F1 score. The proposed ACNN model achieved a maximum accuracy of 98.8%, which is higher than other existing models, according to the experimental results.