• 제목/요약/키워드: medical development

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Gypenoside XVII protects against myocardial ischemia and reperfusion injury by inhibiting ER stress-induced mitochondrial injury

  • Yu, Yingli;Wang, Min;Chen, Rongchang;Sun, Xiao;Sun, Guibo;Sun, Xiaobo
    • Journal of Ginseng Research
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    • 제45권6호
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    • pp.642-653
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    • 2021
  • Background: Effective strategies are dramatically needed to prevent and improve the recovery from myocardial ischemia and reperfusion (I/R) injury. Direct interactions between the mitochondria and endoplasmic reticulum (ER) during heart diseases have been recently investigated. This study was designed to explore the cardioprotective effects of gypenoside XVII (GP-17) against I/R injury. The roles of ER stress, mitochondrial injury, and their crosstalk within I/R injury and in GP-17einduced cardioprotection are also explored. Methods: Cardiac contractility function was recorded in Langendorff-perfused rat hearts. The effects of GP-17 on mitochondrial function including mitochondrial permeability transition pore opening, reactive oxygen species production, and respiratory function were determined using fluorescence detection kits on mitochondria isolated from the rat hearts. H9c2 cardiomyocytes were used to explore the effects of GP-17 on hypoxia/reoxygenation. Results: We found that GP-17 inhibits myocardial apoptosis, reduces cardiac dysfunction, and improves contractile recovery in rat hearts. Our results also demonstrate that apoptosis induced by I/R is predominantly mediated by ER stress and associated with mitochondrial injury. Moreover, the cardioprotective effects of GP-17 are controlled by the PI3K/AKT and P38 signaling pathways. Conclusion: GP-17 inhibits I/R-induced mitochondrial injury by delaying the onset of ER stress through the PI3K/AKT and P38 signaling pathways.

국내의료로봇의 도전과 과제 (Challenge and Problem of Medical Robot Surgery Research)

  • 김광기
    • 대한의용생체공학회:의공학회지
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    • 제30권4호
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    • pp.271-278
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    • 2009
  • Recently, robot research and development was interesting the inside and outside of the country. Medical robot surgery showed diverse advantages according to advanced technical robot research. Also the academic society, research institute and industry showed concerning to the medical robot system. There is a growing need to introduce medical research for aging society. The surgical landscape is quickly changing because of the major driving force of robotics. Robot system and biomedical engineering research as defined a new engine of development show present ways of future revitalization of medical robot system. Medical robot system will be even more utilized when we keeps trying to combine high biomedical technique, IT research, and robot technique. In this review article, we begin with a short historical review of medical robotics, followed by an overview of clinical applications where robots have been applied.

한의사 가운 디자인 제안 (Proposal for the Design of the Oriental Medical Doctor's Gown)

  • 서옥경
    • 대한가정학회지
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    • 제41권11호
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    • pp.113-121
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    • 2003
  • Recently the status of oriental medicine in Korea has been more increased as the alternative medicine which overcome the limitations of western medicine. With the increased status, the development of the oriental medical doctor's gown which is distinguished from that of western medical doctor has been brought up among the oriental medical doctors' group since the middle of 1990. We carried out the former study to know the development's direction of the present oriental medical doctor's gown by the survey the requisites for the oriental medical doctor's gown which they want(OK Suh, 2002). We aim to propose the developed design of the oriental medical doctor's gown which meet their request and has honored tradition according to the data of the former survey. As the result of the production designing of the oriental medical doctor's gown considering tradition, practicality, appreciation of the beautiful etc., in our study, we could lead to distribute 800 gowns through the Association of Korean Oriental Medicine supporting by the brand of Amorepacific's Sulhasoo.

스마트 수술 의료시스템의 비즈니스 생태계 분석 : 특허 네트워크 분석을 중심으로 (Analysis of Business Ecosystem in Smart Surgical Medical System : Focused on Patent Network Analysis)

  • 송영화;최진우;김민수
    • Journal of Information Technology Applications and Management
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    • 제26권2호
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    • pp.75-87
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    • 2019
  • Currently, the nation's medical industry is changing due to the rapid development of technology. In addition, medical accidents occurring in the medical industry are gradually increasing amid the drastic changes. Therefore, a possible solution to medical accidents in the changing health care industry is needed. Accordingly, this study uses network-centrality analysis to examine the business ecosystem of smart surgical medical systems to find ways to increase the efficiency of surgery as well as the resolution of medical accident problems, and to suggest the direction of development of the medical system in the future from a systematic business ecosystem perspective.

한 대학병원의 진료과별 업무성과 평가 도구 개발 과정 (Development of Performance Evaluation Protocols for Physicians in a University Hospital)

  • 김창엽;김선민
    • 한국의료질향상학회지
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    • 제5권2호
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    • pp.296-310
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    • 1998
  • Background : Performance evaluation of medical care providers has become more important than before in Korea. Especially in university hospitals, job contents of medical staffs are so complicated that evaluation is not easily performed. In addition, in order that the feedback of evaluation be successful, acceptance of staffs to be evaluated is essential. This study is aimed at the development of items for evaluation and weighting of each item in one university hospital, and clustering departments by different weight given by medical staffs. Methods : Through resource group meeting. performance items were listed up by categories of education, research, medical services, and other activities in and out of the hospital. For each item, all the medical staffs were asked how important they thought, compared with publishing one original article. By factor analysis, the items in each category were grouped into a few subgroups. In turn, cluster analysis was done for the purpose of grouping departments by priority the medical staffs gave. Results and Conclusion : Among five major categories, medical staffs regard education, research, and medical services more important than other activities in and out of the hospital. Five categories consisted of two or three components. Departments in hospital were grouped into three. However, characteristics of each group was not clearly delineated. This result suggests that more comprehensive tool should be developed and applied in the process of performance evaluation in university hospitals.

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국제보건의료교육과정 개발을 위한 방향성 고찰 (A Study on Direction for the Development of Global Health Education in Korea)

  • 오승민
    • 의학교육논단
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    • 제15권2호
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    • pp.93-99
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    • 2013
  • As a result of the globalization of diseases and the delivery of health care, physicians today are required to understand global health (GH) including the global burden of disease, health inequities, and effective medical aid. Interest in GH among medical students has also increased significantly. To meet these needs and to reflect an increasing focus on social accountability in medical education, global health education (GHE) programs have already been well-established, particularly in North America. Korea's official developmental aid (ODA) volume almost tripled from 2006 to 2011. Korea has committed to double its ODA/gross national income ratio over the next three years. With these increases, interest in GH among medical students has significantly increased. Despite significant interest among medical students, GHE programs have not been properly established in Korea. To develop GHE programs in Korea, proposed GHE curriculum frameworks were reviewed and core values, guiding principles, and GH competencies were identified in the context of the current literature. To identify key themes essential to the development of GHE programs in Korea, the curriculum frameworks should be focused on a global context and should be taught from the perspective of the social, political, and economic causes of ill health.

가톨릭대학교 의과대학 진로지도 교육체제 (Career Path Education System at the College of Medicine, The Catholic University of Korea)

  • 유동미;강화선
    • 의학교육논단
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    • 제26권1호
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    • pp.19-26
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    • 2024
  • This study examines a systematic and effective approach to career guidance in medical education, with a particular focus on the 6-year integrated career guidance education framework implemented at the College of Medicine, The Catholic University of Korea. Based on the "New SLICE" educational development principles, this framework comprehensively addresses the needs of medical students in career planning and development. It is structured into three phases: understanding yourself, exploring options, and choosing a specialty. The first phase, understanding yourself, helps students to recognize their strengths, weaknesses, aptitudes, and potentials, thereby setting the direction for future career choices. This phase includes various psychological tests and Self-Development and Portfolio courses. The second phase, exploring options, enables students to engage in related activities such as research and practical training, providing direct and indirect experiences across various fields. This phase offers courses including Medical Field Experience, Career Guidance through the Learning Community & Advisory Professors, and Student Participation in Professor Research Projects. The final phase, choosing a specialty, involves students making decisions based on in-depth self-assessment and exploration of majors, with a capstone project being a significant component. Maximizing the efficiency of career decision-making requires integration between the basic medical curriculum and postgraduate education. Including the period up to residency entrance in the framework is necessary for effective career guidance education.

Imaging Human Structures

  • Kim Byung-Tae;Choi Yong;Mun Joung Hwan;Lee Dae-Weon;Kim Sung Min
    • 대한의용생체공학회:의공학회지
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    • 제26권5호
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    • pp.283-294
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    • 2005
  • The Center for Imaging Human Structures (CIH) was established in December 2002 to develop new diagnostic imaging techniques and to make them available to the greater community of biomedical and clinical researchers at Sungkyunkwan University. CIH has been involved in 5 specific activities to provide solutions for early diagnosis and improved treatment of human diseases. The five area goals include: 1) development of a digital mammography system with computer aided diagnosis (CAD); 2) development of digital radiological imaging techniques; 3) development of unified medical solutions using 3D image fusion; 4) development of multi-purpose digital endoscopy; and, 5) evaluation of new imaging systems for clinical application

우리나라 전공의 교육 및 관련 인증기관에 대한 통합적 관리계획 (Integrated Management Plan for Graduate Medical Education and Accreditation Bodies in Korea)

  • 임기영
    • 의학교육논단
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    • 제20권3호
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    • pp.123-127
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    • 2018
  • Graduate medical education is the most important phase among the three stages of medical education. It links basic medical education and continuing professional development. It is also a critical period in acquiring meaningful knowledge, skills and professionalism. The residents should be able to develop the core common competencies on top of their specialozeds field's expertise, in order to function as independent and qualified physicians. Despite the obvious importance of graduate medical education, the system in Korea has been designed and executed to meet the needs of the hospitals in the perspective of manpower management, rather than to educate and empower the residents. As a result, graduate medical education in Korea lacks clear educational objectives and systemic, resident-centered curriculums. Yet, we have no accreditation body to evaluate graduate medical education programs. In order to normalize graduate medical education, an integrated and unified institution that manages the whole process of the graduate medical education is desperately needed. Special attention should be given to the role of medical schools in educating the core common competencies. The Korean Association of Medical Colleges, the Korean Institute for Medical Education and Evaluation, and the Korean Academy of Medical Sciences should cooperate intimately to establish a new organization for the systemic management and development of graduate medical education.

Scout 영상 기반의 의료영상 정보시스템 구현 (Implementation of a scout image-based medical image information system)

  • 김재준
    • 전자공학회논문지CI
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    • 제44권3호
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    • pp.43-48
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    • 2007
  • 초고속 인터넷의 발달과 휴대용 임베디드시스템이 보편화된 유비쿼터스 환경 아래에서 의료영상처리 분야에도 언제 어디서든지 원하는 환자에 대한 정보를 검색하고 판독할 수 있는 시스템에 대한 연구 및 개발이 활발하게 이루어지고 있다. 특히, scout 영상은 진단 목적 이외에 새로운 응용분야에서 필요로 하고 있다. 유비쿼터스 시스템 개발로 의료 영상 뷰어는 PACS 시스템 및 웹브라우저와 결합한 병원에서 활용되고 있다. 본 논문은 무선 환경에서 잠재력을 보여주고 있는 이동단말기 기반의 의료영상 뷰잉시스템을 구현하였다.