• 제목/요약/키워드: matrix correlation

검색결과 782건 처리시간 0.029초

Mathematical explanation on the POD applications for wind pressure fields with or without mean value components

  • Zhang, Jun-Feng;Ge, Yao-Jun;Zhao, Lin;Chen, Huai
    • Wind and Structures
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    • 제23권4호
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    • pp.367-383
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    • 2016
  • The influence mechanism of mean value components, noted as $P_0$, on POD applications for complete random fields $P_C(t)$ and fluctuating random fields $P_F(t)$ are illustrated mathematically. The critical philosophy of the illustration is introduction of a new matrix, defined as the correlation function matrix of $P_0$, which connect the correlation function matrix of $P_C(t)$ and $P_F(t)$, and their POD results. Then, POD analyses for several different wind pressure fields were presented comparatively as validation. It's inevitable mathematically that the first eigenmode of $P_C(t)$ resembles the distribution of $P_0$ and the first eigenvalue of $P_C(t)$ is close to the energy of $P_0$, due to similarity of the correlation function matrixs of $P_C(t)$ and $P_0$. However, the viewpoint is not rigorous mathematically that the first mode represents the mean pressure and the following modes represent the fluctuating pressure when $P_C(t)$ are employed in POD application. When $P_C(t)$ are employed, POD results of all modes would be distorted by the mean value components, and it's impossible to identify $P_0$ and $P_F(t)$ separately. Consequently, characteristics of the fluctuating component, which is always the primary concern in wind pressure field analysis, can only be precisely identified with $P_0$ excluded in POD.

Expression of RECK and MMPs in Hepatoblastoma and Neuroblastoma and Comparative Analysis on the Tumor Metastasis

  • Xu, Meng;Wang, Hai-Feng;Zhang, Huan-Zhi
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권9호
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    • pp.4007-4011
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    • 2015
  • Objective: To explore the expression of RECK and relevant matrix metalloproteinases (MMPs) in hepatoblastoma (HB) and neuroblastoma (NB) and their clinical significance in the tumor metastasis. Materials and Methods: Forty-five wax-stone samples of HB and 43 wax-stone samples of NB removed by surgical resection and confirmed by pathology in Linyi Yishui Central Hospital were selected. According to presence and absence of metastasis, both NB and HB samples were divided into metastatic group and non-metastatic group, namely NB metastatic group (n=28), NB non-metastatic group (n=15), HB metastatic group (n=15) and HB non-metastatic group (n=30). The expression of RECK, membrane type-1 matrix metalloproteinase (MT1-MMP) in HB tissue and RECK, MMP-14 in NB tissue was detected using immunohistochemical method, and the correlation between RECK and MT1-MMP, MMP-14 was analyzed. Results: The metastatic rate of NB was dramatically higher than that of HB, with statistical significance (P=0.003). The positive rate of RECK expression in NB group (30.2%) was slightly lower than in HB group (40.0%), but no significant difference was presented (P=0.338). The positive rate of MMPs expression in NB metastatic group was evidently higher than in HB metastatic group (P=0.024). The results of Spearman correlation analysis revealed that the expression of RECK in HB and NB tissues had a significantly-negative correlation with MT1-MMP and MMP-14, respectively (r=-0.499, P=0.012; r=-0.636, P=0.000). Conclusions: In HB and NB tissues, RECK is expressed lowly, while relevant MMPs highly, and RECK inhibits the tumor invasion and metastasis through negative regulation of relevant MMPs.

Changes in Matrix Metalloproteinase and Tissue Inhibitors of Metalloproteinase in Patients with Rotator Cuff Tears

  • Kwon, Oh-Soo;Kim, Young-Yul;Ha, Ji Yoon;Kang, Han Bit
    • Clinics in Shoulder and Elbow
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    • 제17권2호
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    • pp.64-67
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    • 2014
  • Background: The purpose of this study was to determine whether in patients with rotator cuff tears a correlation exists between molecular changes and clinical parameters such as age, duration of symptom, range of motion, and tear size. Molecular changes of matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) were assessed by measuring messenger RNA (mRNA) levels of the two proteins. Methods: The rotator cuff tissue from was obtained from the edge of a torn tendon revealed after debridement by a motorized shaver. Using the sample of rotator cuff tissue, the reverse transcription polymerase chain reaction was performed to quantify MMP-2 and TIMP-2 mRNA expression. To determine whether mRNA levels and the clinical variables, such as age, defect size, range of motion (ROM) of shoulder, and duration of symptoms, show any correlation, Spearman's correlation coefficients were used to test for significant differences. Results: There was an inverse correlation between the mRNA levels of MMP-2 and TIMP-2 from the torn rotator cuff tendons regardless of the clinical variables. However, comparison of mRNA levels versus clinical parameters such as age, defect size, range of motion and duration of symptoms revealed a number of findings. We found a significant correlation between age and mRNA levels of MMP-2 from torn cuffs (r = 0.513, p = 0.021). Further, we found a significant correlation between defect size in the full thickness tears and mRNA levels of MMP-2 (r = 0.454, p = 0.045). Conversely, no significant association between mRNA levels of MMP-2 and ROM or duration of symptom was found. Conclusions: Our results suggest that both MMP-2 and TIMP-2 may be involved in the disease process of rotator cuff tears. Although the level of mRNA expression of MMP-2 and TMP-2 remain constant in torn rotator cuffs irrespective of the clinical variables, their levels may be influenced by age and defect size, which could account to change in tendon degradation and the healing process.

비소세포폐암에서 Matrix Metalloproteinase(MMPs)-2, 9와 Tissue Inhibitor of Metalloproteinase(TIMPs)-1, 2의 발현과 생존율과의 관계 (The Relationship Between Expression of Matrix Metalloproteinases(MMPs)-2, 9 and Tissue Inhibitors of Metalloproteinase(TIMPs)-1, 2 and Survival Time in Resected Non-Small Cell Lung Cancer)

  • 김학렬;양세훈;정은택
    • Tuberculosis and Respiratory Diseases
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    • 제52권5호
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    • pp.453-462
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    • 2002
  • 연구배경 : MMPs는 종양 전이의 주된 장벽인 기저막과 세포외 기질을 분해하여 암세포의 침습 및 전이에 주된 역할을 하며, TIMP는 MMP에 의한 기저막 단백질 분해를 억제하는 인자로 알려져있다. MMP의 발현은 임상 병기가 진행할수록 증가하며 주위 림프절 전이와 관계가 있으며, TIMP의 발현은 주위 림파절로 전이가 일어나면 감소 또는 증가하는 것으로 알려져 있다. 대상 및 방법 : 비소세포폐암으로 진단 받고 근치적 절제술을 시행 받은 74명 환자를 대상으로 paraffin에 보관된 조직에서 면역조직화학염색법을 이용하여 MMP-2, 9, TIMP-l, 2 항체로 발현을 검색하였으며, 발현에 따른 생존율을 Kaplan-Meier, Log-rank로 검색하였다. 결 과 : MMP-2, 9의 발현은 각각 25/74례 (34%), 19/74(26%)였고, TIMP-l, 2의 발현은 각각 27/74(36%), 32/74(43%)였다. 임상 병기에 따른 MMP-2, 9 발현은 병기의 진행에 따라 유의하게 증가하였고, TIMP-2는 유의하게 감소하였다. 임상 림프절의 전이에 따른 발현은 MMP-2, 9에서만 전이의 진행에 따라 유의하게 증가하였다. MMP-2 발현에 따른 중간 생존기간은 양성군이 20개월, 음성군이 34개월로 양성군이 유의하게 낮았으며, TIMP-2은 34개월, 18개월로 양성군이 유의하게 높았다. MMP-2/TIMP-2에 따른 중간 생존기간은 음성/양성이 유의하게 높았다. 결 론 : MMP-2, 9 발현은 종양의 진행과 림프절의 전이에 관여할 것으로 사료되며, MMP-2와 TIMP-2의 발현은 역비레 관계가 있다.

간호사의 역할갈등 측정을 위한 도구 개발 연구 (Development of a Role Conflict Scale for Clinical Nurses)

  • 김문실;박상연
    • 대한간호학회지
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    • 제25권4호
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    • pp.741-750
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    • 1995
  • The purpose of this study was to develop a role conflict scale for nurses in hospitals. The process of study was as follows. The first step was the study of selected literature on role conflict in general and to translate into Korean language the role conflict and ambiguity scale developed by House. From this process, a scale for role conflict inventory-general was made by consulting with two professors majored in educational evaluation and one professor who is an authory on educational administration. In the second step, 24 clinical nurses were asked to describe the situations having job-related role conflict. In the third step, the role conflict inventory-specific was derived from the role conflict inventory -general, and data selected from the step two. The confidence and clarity of this role conflict inventory-specific was strengthed by consulting one clinical psychologist, two professors of nursing college and ten doctoral students of nursing. With this tool being tested, the results are summarized as follows. 1. Reliability Internal consistency reliability was tested by cronbach alpha, corrected item total correlation and correlation matrix. The cronbach alpha level was .94 and one item among 37 items was below .35 and the rest items were .42 above in the corrected item total correlation. There was no negative correlation in the correlation matrix. 2. Construct validity In the construct validity test, four factors have an eigen value 1.0 over, Factor 1 represented role ambiguity, composed of 15 items with .90 reliability level. Factor 2 represented deficiency of ability and skill, composed of 11 items with .90 of reliability level. Factor 3 represented working environment, composed of 6 items with .85 of reliability level. Final factor represented deficiency of job-related collaboration, composed of 5 items with .69 reliability level. These results contribute to measuring the level of role conflict for nurses, and to the managment of the nurses' role conflict.

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혼합모형을 이용한 반복 측정된 변수들 간의 상관분석 (Assessing Correlation between Two Variables in Repeated Measurements using Mixed Effect Models)

  • 한경화;정인경
    • 응용통계연구
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    • 제28권2호
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    • pp.201-210
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    • 2015
  • 생명과학 또는 의학 연구에서는 반복 측정된 변수들 간의 상관 관계를 보고자 하는 경우가 발생한다. 반복 측정된 것을 고려하지 않으면 상관관계를 과소 추정하는 경향이 나타나므로 이를 고려해야 하며, 선형혼합모형의 분산-공분산 행렬을 이용하여 상관관계를 추정할 수 있다. 본 연구에서는 변수들의 반복 측정이 동시에 된 경우와 그렇지 않은 경우로 나누어 혼합모형을 이용한 상관계수의 추정방법을 소개한다. 고속 음향 복사력 임펄스 영상(acoustic radiation force impulse imaging; ARFI)으로 간과 비장에서 각각 세 번씩 전단파 속도를 반복 측정하고 복부 초음파 검사로 비장 길이를 측정한 자료에서 전단파 속도와 비장 길이 간의 상관 관계를 분석하기 위해 본 논문에서 소개한 방법들을 적용하였고 SAS의 PROC MIXED를 이용하는 방법을 제시하였다.

Correlation plot for a contingency table

  • Hong, Chong Sun;Oh, Tae Gyu
    • Communications for Statistical Applications and Methods
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    • 제28권3호
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    • pp.295-305
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    • 2021
  • Most graphical representation methods for two-dimensional contingency tables are based on the frequencies, probabilities, association measures, and goodness-of-fit statistics. In this work, a method is proposed to represent the correlation coefficients for each of the two selected levels of the row and column variables. Using the correlation coefficients, one can obtain the vector-matrix that represents the angle corresponding to each cell. Thus, these vectors are represented as a unit circle with angles. This is called a CC plot, which is a correlation plot for a contingency table. When the CC plot is used with other graphical methods as well as statistical models, more advanced analyses including the relationship among the cells of the row or column variables could be derived.

완전 디지털 능동배열 레이다의 적응형 부엽제거 알고리즘에 관한 연구 (Analysis of Adaptive Side-Lobe Canceller Algorithm for Fully Digital Active Array Radar)

  • 양우용;박민규;홍성원;김찬홍
    • 한국전자파학회논문지
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    • 제29권5호
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    • pp.375-382
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    • 2018
  • 레이다는 강한 재밍신호를 제거하기 위해 부엽제거 알고리즘을 이용하여 상대적으로 약한 표적신호를 획득한다. 본 논문에서는 완전 디지털 능동배열 레이다에서 적용 가능한 새로운 적응형 부엽제거 알고리즘을 제안한다. 먼저 부엽제거 빔 신호를 이용하여 공분산 행렬을 구한다. 그리고 부엽제거 빔 신호와 주빔 신호와의 상관행렬을 산출한 후, 적응형 부엽제거 빔 형성 계수를 획득한다. 그 후 수신되는 주빔 신호와의 연산을 통해 최종적으로 재밍신호가 제거된 표적신호를 구한다. 시뮬레이션 신호로의 적용 결과를 통해 제안된 알고리즘이 부엽제거에 효과적임을 확인하였고, 실제 레이다에 적용하기 위한 여러 고려사항들을 분석하여 체계 적용성을 높였다.

스테레오 음향학적 에코 제거를 위한 Soft Decision 기반 필터 확장 기법 (Spectro-Temporal Filtering Based on Soft Decision for Stereophonic Acoustic Echo Suppression)

  • 이철민;배수현;김정훈;김남수
    • 한국통신학회논문지
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    • 제39C권12호
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    • pp.1346-1351
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    • 2014
  • 본 논문은 스테레오 환경에서 발생하는 음향학적 에코 신호를 효율적으로 제거하기 위하여 시간 및 주파수 상관관계 (spectro-temporal correlation) 를 고려한 필터링을 제안하였다. 기존의 에코 패스를 직접 추정하는 방식에서 벗어나 동시 통화 검출 기법 없이 에코 스펙트럼을 추정하는 음향학적 에코 억제 기법 (acoustic echo suppression, AES) 을 적용하였다. 개선된 에코 추정을 위해 확장된 파워 스펙트럼 밀도 행렬 (extended power spectrum density matrix) 과 에코 과추정 조절 행렬 (echo overestimation control matrix) 을 도입하였다. 또한, 주파수 영역에서 음성이 존재하지 않을 확률을 적용한 soft decision 기반의 본 기법을 통해 스테레오 환경에서의 음향학적 에코 신호 제거 성능이 기존 기법에 비해 보다 향상됨을 확인하였다.

웨이브렛 분해를 이용한 유색잡음 환경하의 도래각 추정 (Direction of Arrival Estimation in Colored Noise Using Wavelet Decomposition)

  • 김명진
    • 대한전자공학회논문지SP
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    • 제37권6호
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    • pp.48-59
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    • 2000
  • 안테나 센서 어레이를 이용하여 수신되는 전파의 도래각을 추정하는 방식으로서 MUSIC(multiple signal classification)과 같은 고유분해(eigendecomposition)를 기반으로 한 방식은 백색잡음 환경하에서는 고분해능의 우수한 성능을 보이지만 유색잡음이 존재하는 환경에서는 성능이 크게 저하된다. 본 논문에서는 주기성을 가진 신호에 잡음이 더해진 선호를 웨이브렛 영역으로 변환하여 신호와 잡음을 분리하는 방법을 사용하여 유색잡음이 있는 환경에서 도래각 추정 문제를 접근하였다. 배경잡음만 있는 경우 센서 어레이 출력을 이산 웨이브렛 분해를 하여 얻은 멀티스케일 성분들의 공분산 행렬은 밴드화된 행렬로 근사화 할 수 있는데 비하여 협대역 신호는 멀티스케일 성분간의 상관성은 급속히 감소하는 현상을 보이지 않고 공분산 행렬에서는 신호성분이 전체 행렬에 분포한다. 어레이 출력의 공분산 행렬을 웨이브렛 영역으로 변환하여 유색잡음에 해당하는 특정 밴드를 삭제하고 MUSIC과 같은 기존의 공간 스펙트럼 추정방식을 적용하여 도래각을 추정 한 다음 그 결과로 부터 신호성분을 합성하여 삭제한 밴드를 채우는 과정을 반복하여 정확한 도래각을 얻는 방안을 제안하였다. 제안된 알고리즘의 성능을 여러 가지 형태의 상관함수 특성을 가진 유색잡음 환경에서 모의실험을 통하여 기존 방식과 비교 분석하였다.

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