• 약학회지
• /
• 제36권1호
• /
• pp.26-36
• /
• 1992

The metabolic profile of triprolidine, 2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl-1-propenyl)] pyridine, was determined in rat urine and bile. The free fractions of urinary and biliary extracts were obtained without hydrolysis, and the conjugated fractions of extracts were obtained with enzyme hydrolysis using ${\beta}-glucuronidase$ from Escherichia coli. The mixture of N-methyl-N-trimethylsilyltrifluoroacetamide/trimethylsilyl chloride (100 : 1, v/v) was used to derivatize the extracts and then analyzed by gas chromatography/mass spectrometry. Hydroxymethyltriprolidine, hydroxytriprolidine, triprolidine carboxylic acid, dihydroxytriprolidine 1, dihydroxytriprolidine 2, oxotriprolidine carboxylic acid and unchanged triprolidine were detected in rat urine and bile, which were obtained after oral treatment with triprolidine hydrochloride. The maximum urinary excretion rate of triprolidine and hydroxymethyltriprolidine which were extracted from free fraction was at 1 to 2 hours after drug administration. Hydroxymethyltriprolidine was detected in conjugated fraction, and the maximum urinary excretion rate of that metabolite was at 2 to 3 hours in rat. In rat bile analysis, triprolidine was detected only in free fraction and its biliary excretion rate showed the maximum within 30 minutes after drug administration and decreased continuously thereafter. The excretion percentage of triprolidine and hydroxymethyltriprolidine to the initial dose of the parent drug in bile and urine of rats were all low.

• Advances in aircraft and spacecraft science
• /
• 제9권3호
• /
• pp.169-193
• /
• 2022

By the present paper, both experimental and analytical models have been proposed to study the vibration behavior of partially bio-sourced sandwich panel with orthogonally stiffened core. For a variable mass fraction of Alfa fibers from 5% to 15%, impregnated in a Medapoxy STR resin, this panel were manufactured by molding the orthogonally stiffened core then attached it with both skins. Using simply supported boundary conditions, a free vibration test was carried out using an impact hammer for predicting the natural frequencies, the mode shapes and the damping coefficient versus the fibers content. In addition, an analytical model based on the Higher order Shear Deformation Theory (HSDT) was developed to predict natural frequencies and the mode shapes according to Navier's solution. From the experimental test, we have found that the frequency increases with the increase in the mass fraction of the fibers until 10%. Beyond this fraction, the frequencies give relatively lower values. For the analytical model, variation of the natural frequencies increased considerably with side-to-thickness ratio (a/H) and equivalent thickness of the core to thickness of the face (h_s/h). We concluded that, the vibration behavior was significantly influenced by geometrical and mechanical properties of the partially bio-sourced sandwich panel.

• 분석과학
• /
• 제26권6호
• /
• pp.401-406
• /
• 2013

유정란의 부화과정 동안 소모되는 산소와 배출되는 이산화탄소의 양을 기체질량분석기를 사용하여 측정하였다. 20 일에 걸친 유정란과 무정란의 인공부화 과정 동안 기체 시료를 채취하기 위해 밀폐된 구조의 시료 챔버를 제작하였다. 2~4 일 간격으로 시료 챔버 안에 유정란을 1 시간 동안 방치한 후, 실린지를 이용해 밀폐된 시료 챔버로부터 2 mL의 기체 시료를 채취한 후 기체질량분석기를 사용하여 분석하였다. 인공부화를 시작한 후 약 10 일 후부터 닭 배아의 산소 소모량과 이산화탄소 배출량이 급격히 증가하였다. 20 일 후에는 시간당 23 mL의 산소를 소모하고 16 mL의 이산화탄소를 배출하였다. 전체 부화 기간 동안 산소의 농도는 4.3 mol% 감소하였고 이산화탄소의 농도는 3.1 mole% 증가하여 소모된 산소의 몰수와 배출된 이산화탄소의 몰수가 같지 않았다. 한편, 동일한 기간 동안 질소의 농도는 약 1.3 mol% 증가하였으며 그 증가된 농도는 소모된 산소와 배출된 이산화탄소의 농도변화량의 차이와 비슷한 값을 보였다. 따라서 질소의 몰분율 증가는 소모된 산소와 배출된 이산화탄소 간의 몰분율 차이에 의한 것임을 알 수 있었다. 본 연구에서는 기체의 조성 변화량을 정확히 측정하여 유정란의 부화과정 중 호흡현상을 설명할 수 있었다.

• 한국응용곤충학회지
• /
• 제36권1호
• /
• pp.88-95
• /
• 1997

매미나방(Lymantria dispar)에서 추출된 카이로몬을 이용하여 난기생천적인 짚시알깡충좀벌(Ooencyrtus kuvanae)에 대한 유인성을 olfactormeter로 측정하였다. 매미나방알의 인편과 털에서 추출한 카이로몬은 79.9%의 유인성을 나타내어 알에서 추출한 카이로몬의 67.6%보다 높은 유인력을 나타내었다. 짚시알깡충좀벌의 탐색시간은 인편과 털의 추출물에서 115.5초 인편과 털을 제거하지 않은 알에서 113.2초로 유사하였다. 정상적으로 산란된 기주알에 대해서는 91.0%가 유인되어서 난소에서 적출한 미성숙알의 15%보다 크게 높았으며 탐침까지의 시간은 84.2초로 난수에서 적출한 알의 114.0초보다 짧았다. 생식부속샘에서 분비되는 접착물질은 88%로서 가장 높은 반응을 보였고, 탐색시간은 89.2초, 최초탐침시간은 26.8초를 나타냈다. 6종류의 유기용매를 사용하여 추출한 카이로몬을 대상으로 짚시알깡충좀벌의 유인도를 조사한 결과 n-hexane의 추출물에서 가장활발한 반응을 나타냈으며 자연난에서 우화한 것이 인공난에서 우화한것보다 3배이상 높은 반응을 보였다.

• 천문학회보
• /
• 제38권2호
• /
• pp.40.1-40.1
• /
• 2013

We perform a set of N-body/SPH simulations of galaxy interactions between early- and late-type galaxies with the mass ratio of 2 to 1. We show that mass transfer during a fly by interaction (the closest approach distance ~50kpc) can cause the morphology transformation of an early-type galaxy to a late type. In our simulations, we vary the orbital parameters of the interactions and the cold gas fraction of the late-type galaxy to compare how the morphology transformation is affected by the amount of mass transfer and orbital angular momentum of cold gas accreted to the early type. We also include hot halo gas in the galaxy models and show the location of the tidal bridge can be influenced by the shock generated during the collision.

• Mass Spectrometry Letters
• /
• 제7권1호
• /
• pp.12-15
• /
• 2016

Results of free and bound myo-inositol in infant formula (IF) are presented. Inositol was analyzed by HILIC ultra-performance liquid chromatography coupled with mass spectrometer. The levels of free myo-inositol in 27 Australian and 4 EU originated IF samples were 300-600 mg/kg of powder or 1.6-3.1 mg/100 kJ. The amount of bound inositol in lipid fraction of IF was, on average, 10% of free myo-inositol.

• Nuclear Engineering and Technology
• /
• 제38권1호
• /
• pp.69-80
• /
• 2006

Fluid-elastic instability in an air-water two-phase cross-flow has been experimentally investigated using two different arrays of straight tube bundles: normal square (NS) array and rotated square (RS) array tube bundles with the same pitch-to-diameter ratio of 1.633. Experiments have been performed over wide ranges of mass flux and void fraction. The quantitative tube vibration displacement was measured using a pair of strain gages and the detailed orbit of the tube motion was analyzed from high-speed video recordings. The present study provides the flow pattern, detailed tube vibration response, damping ratio, hydrodynamic mass, and the fluid-elastic instability for each tube bundle. Tube vibration characteristics of the RS array tube bundle in the two-phase flow condition were quite different from those of the NS array tube bundle with respect to the vortex shedding induced vibration and the shape of the oval orbit of the tube motion at the fluid-elastic instability as well as the fluid-elastic instability constant.

• 한국환경과학회지
• /
• 제1권2호
• /
• pp.25-31
• /
• 1992

Authors Investigated the particulate size distribution in work environment of Banwol and Changwon industry complex. Size distributions of particles exposured to workers in welding and in grounding process were evaluated by personal cascade impactors. Personal air samplers with personal cascade impactor were attached to the workers. The mass median diameter measured in welding sites were 0.3 to 3.BUm and in grinding sites were 1.5 to 2.6htn. Respirable matter fractions were ranged 32.67 to 65.055. Respirable matter fractions were calculated from the sixte distribution data by the respirable particle mass of the ACGIH criteria. The study relating to characteristics of particle of other industries and particulate sixte distribution is more needed in the near future

• 한국산업보건학회지
• /
• 제1권1호
• /
• pp.62-67
• /
• 1991

석탄광산에서 발생하는 갱내 부유분진의 입경분포와 부유분진 중에서 호흡성 분진이 차지하는 비율을 파악하기 위하여 태백, 화순, 점촌 지역의 일부 석탄광산을 대상으로 조사한 결과를 요약하면 다음과 같다. 1. 굴진막상의 부유분진의 입경이 가장 작으며 대표입경이 ACGlH(1989)에서 정의한 호흡성 분진의 입경보다 작고 채탄막장의 입경은 호흡성 분진의 입경과 같으며 선탄장의 입경도 기관지 침착성 분진의 입경을 나타내고 있다. 2. 굴진부서의 공기 중에 부유하고 있는 분진 중에서 호흡성 분진이 차지하는 비율이 다른 부서에 비하여 가장 높게 나타났다.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 2004년도 한국우주과학회보 제13권1호
• /
• pp.24-24
• /
• 2004

Using stellar population synthesis techniques, we explore the photometric signatures of white dwarf progenitor dominated galactic halos, in order to constrain the fraction of halo mass that may be locked-up in white dwarf stellar remnants. We first construct a 10＾9 M_sun stellar halo using the canonical Salpeter initial stellar mass distribution, and then allow for an additional component of low-and intermediate-mass stars, which ultimately give rise to white dwarf remnants. (omitted)