• 제목/요약/키워드: mass configuration

검색결과 397건 처리시간 0.019초

Oligomeric Structure of the ATP-dependent Protease La (Lon) of Escherichia coli

  • Park, Seong-Cheol;Jia, Baolei;Yang, Jae-Kyung;Le Van, Duyet;Shao, Yong Gi;Han, Sang Woo;Jeon, Young-Joo;Chung, Chin Ha;Cheong, Gang-Won
    • Molecules and Cells
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    • 제21권1호
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    • pp.129-134
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    • 2006
  • Lon, also known as protease La, belongs to a class of ATP-dependent serine protease. It plays an essential role in degradation of abnormal proteins and of certain short-lived regulatory proteins, and is thought to possess a Ser-Lys catalytic dyad. To examine the structural organization of Lon, we performed an electron microscope analysis. The averaged images of Lon with end-on orientation revealed a six-membered, ring-shaped structure with a central cavity. The side-on view showed a two-layered structure with an equal distribution of mass across the equatorial plane of the complex. Since a Lon subunit possesses two large regions containing nucleotide binding and proteolytic domains, each layer of the Lon hexamer appears to consist of the side projections of one of the major domains arranged in a ring. Lon showed a strong tendency to form hexamers in the presence of $Mg^{2+}$, but dissociated into monomers and/or dimers in its absence. Moreover, $Mg^{2+}$-dependent hexamer formation was independent of ATP. These results indicate that Lon has a hexameric ring-shaped structure with a central cavity, and that the establishment of this configuration requires $Mg^{2+}$, but not ATP.

Grain Geometry, Performance Prediction and Optimization of Slotted Tube Grain for SRM

  • Nisar, Khurram;Liang, Guozhu
    • 한국추진공학회:학술대회논문집
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    • 한국추진공학회 2008년 영문 학술대회
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    • pp.293-300
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    • 2008
  • Efficient designing of SRM Grains in the field of Rocketry is still the main test for most of the nations of world for scientific studies, commercial and military applications. There is a strong need to enhance thrust, improve the effectiveness of SRM and reduce mass of motor and burning time so as to allow the general design to increase the weight of payload/on board electronics. Moreover burning time can be increased while keeping the weight of the propellant and thrust in desired range, so as to give the time to control / general design group in active phase for incorporating delayed cut off if required. A mathematical design, optimization & analysis technique for Slotted Tube Grain has been discussed in this paper. In order to avoid the uncertainties that whether the Slotted Tube grain configuration being designed is best suited for achieving the set design goals and optimal of all the available designs or not, an efficient technique for designing SRM Grain and then getting optimal solution is must. The research work proposed herein addresses and emphasizes a design methodology to design and optimize Slotted Tube Grain considering particular test cases for which the design objectives and constraints have been given. In depth study of the optimized solution have been conducted thereby affects of all the independent parametric design variables on optimal solution & design objectives have been examined and analyzed in detail. In doing so, the design objectives and constraints have been set, geometric parameters of slotted tube grain have been identified, performance prediction parameters have been calculated, thereafter preliminary designs completed and finally optimal design reached. A Software has been developed in MATLAB for designing and optimization of Slotted Tube grains.

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Vortex induced vibration and its controlling of long span Cross-Rope Suspension transmission line with tension insulator

  • Tu, Xi;Wu, Ye;Li, Zhengliang;Wang, Zhisong
    • Structural Engineering and Mechanics
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    • 제78권1호
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    • pp.87-102
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    • 2021
  • Long span cross-rope suspension structure is an innovative structural system evolved from typical Cross-Rope Suspension (CRS) guyed tower, a type of supporting system with short span suspension cable supporting overhead power transmission lines. In mountainous areas, the span length of suspension cable was designed to be extended to hundreds or over one thousand meters, which is applicable for crossing deep valleys. Vortex Induced Vibration (VIV) of overhead power transmission lines was considered to be one of the major factors of its fatigue and service life. In this paper, VIV and its controlling by Stockbridge damper for long span CRS was discussed. Firstly, energy balance method and finite element method for assessing VIV of CRS were presented. An approach of establishing FE model of long span CRS structure with dampers was introduced. The effect of Stockbridge damper for overall vibration of CRS was compared in both theoretical and numerical approaches. Results indicated that vibration characteristics of conductor in long span CRS compared with traditional tower-line system. Secondly, analysis on long span CRS including Stockbridge damper showed additional dampers installed were essential for controlling maximum dynamic bending stresses of conductors at both ends. Moreover, factors, including configuration and mass of Stockbridge damper, span length of suspension cable and conductor and number of spans of conductor, were assessed for further discussion on VIV controlling of long span CRS.

습식 화학적 식각 방법에 의한 시간에 따른 GaAs(100) 단결정 웨이퍼에서의 마이크로 구멍의 제작 및 분석 (Fabrication and Time-Dependent Analysis of Micro-Hole in GaAs(100) Single Crystal Wafer Using Wet Chemical Etching Method)

  • 이하영;곽민섭;임경원;안형수;이삼녕
    • 한국재료학회지
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    • 제29권3호
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    • pp.155-159
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    • 2019
  • Surface plasmon resonance is the resonant oscillation of conduction electrons at the interface between negative and positive permittivity material stimulated by incident light. In particular, when light transmits through the metallic microhole structures, it shows an increased intensity of light. Thus, it is used to increase the efficiency of devices such as LEDs, solar cells, and sensors. There are various methods to make micro-hole structures. In this experiment, micro holes are formed using a wet chemical etching method, which is inexpensive and can be mass processed. The shape of the holes depends on crystal facets, temperature, the concentration of the etchant solution, and etching time. We select a GaAs(100) single crystal wafer in this experiment and satisfactory results are obtained under the ratio of etchant solution with $H_2SO_4:H_2O_2:H_2O=1:5:5$. The morphology of micro holes according to the temperature and time is observed using field emission - scanning electron microscopy (FE-SEM). The etching mechanism at the corners and sidewalls is explained through the configuration of atoms.

대량 처리 엔진(ElasticSearch)을 이용한 시스템 및 어플리케이션 성능 모니터링 시스템에 관한 연구 (A Study on System and Application Performance Monitoring System Using Mass Processing Engine(ElasticSearch))

  • 김승천;장희돈
    • 디지털융복합연구
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    • 제17권9호
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    • pp.147-152
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    • 2019
  • 사물인터넷(IoT), 빅데이터(BigData) 및 인공지능(AI)과 같은 최신 IT 기술로 인터넷 비즈니스가 성장함에 따라 인프라가 빠르게 성장하고 있습니다. 그러나 대부분의 회사에서는 제한된 수의 사람들이 많은 하드웨어와 소프트웨어를 관리해야합니다. 따라서 시스템 운영 상태, IT 서비스 및 주요 핵심성과지표(KPI, Key Performance Indicator)를 모니터링하기 위한 PEMS (Polestar Enterprise Management System)을 적용합니다. 실시간 모니터 스크리닝은 시스템 오작동 및 빠른 응답을 방지합니다. PEMS를 사용하면 IT 하드웨어 및 소프트웨어와 관련된 구성 정보를 한눈에 볼 수 있으며 전체 종단 간 성능을 모니터링하여 문제가 실시간으로 발생하는 시기를 확인할 수 있습니다.

3축 분력 측정이 가능한 대형 공구동력계 개발 (Development of Large-scale Tool Dynamometer for Measuring Three-axis Individual Force)

  • 김중선;왕덕현
    • 한국기계가공학회지
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    • 제18권5호
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    • pp.29-36
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    • 2019
  • In modern society in which the fourth industrial revolution has come to the fore and rapid technology innovations are taking place, a phenomenon of making and selling small quantities of various products that consumers want instead of mass producing one item has emerged. As the market is moving toward the multi-item small-sized production system, there is a need for a system in which a machine independently judges and carries out machining and post-processing. In order for a machine to judge processing on its own, it is necessary to measure the force applied to a product. This study aimed to develop a large-scale dynamometer that enables three-axis measurement using octagonal ring load cells. As for the device's configuration, four octagonal ring load cells, which were previously researched, were used to enable three-axis measurement. It was reconfigured by modifying the attachment position of the octagonal ring load cells' strain gauge and the Wheatstone bridge of each axis, and a system was set up to allow the monitoring of data measured through the monitor. The configured device calculated a strain rate by an experiment, and this rate was compared with the theoretical strain rate to find a correction value. The correction value was entered into a formula, deriving a modified formula. The modified formula was entered into the device, which completed the large-scale dynamometer.

흉부 디지털 영상의 병변 유무 판단을 위한 딥러닝 모델 (A Deep Learning Model for Judging Presence or Absence of Lesions in the Chest X-ray Images)

  • 이종근;김선진;곽내정;김동우;안재형
    • 한국정보통신학회논문지
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    • 제24권2호
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    • pp.212-218
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    • 2020
  • 흉부 영상을 통해 진단 가능한 병변은 무기폐, 심비대, 덩어리, 기흉, 삼출 등 그 종류가 수십 가지에 이른다. 흉부 병변의 정확한 진단과 위치 및 크기를 판단하기 위해 일반적으로 전산화단층촬영(CT) 검사가 필요하지만, 전산화단층촬영은 검사 비용과 방사선 피폭 등의 단점이 있다. 따라서 본 논문에서는 흉부 병변 진단의 일차적 선별도구로서 방사선검사(X-ray) 영상에서 병변 유무 판단을 위한 딥러닝 알고리즘을 제안한다. 제안하는 알고리즘은 병변의 유무 판단에 최적화하기 위해 다양한 구성 방법들을 비교하여 설계하였다. 실험 결과, 기존 알고리즘보다 병변 유무 판단률이 약 1% 정도 향상되었다.

소형 GM 냉동기를 이용한 수소 액화에 관한 시뮬레이션 연구 (A Simulation Study on the Hydrogen Liquefaction through Compact GM Refrigerator)

  • 정하늘;한단비;양원균;백영순
    • 한국수소및신에너지학회논문집
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    • 제33권5호
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    • pp.534-540
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    • 2022
  • Liquid hydrogen has the best storage capacity per unit mass and is economical among storage methods for using hydrogen as fuel. As the demand for hydrogen increases, the need to develop a storage and supply system of liquid hydrogen is emphasizing. In order to liquefy hydrogen, it is necessary to pre-cool it to a maximum inversion temperature of -253℃. The Gifford-McMahon (GM) refrigerator is the most reliable and commercialized refrigerator among small-capacity cryogenic refrigerators, which can extract high-efficiency hydrogen through liquefied hydrogen production and boil of gas re-liquefaction. Therefore, in this study, the optimal conditions for liquefying gas hydrogen were sought using the GM cryocooler. The process was simulated by PRO/II under various cooling capacities of the GM refrigerator. In addition, the flow rate of hydrogen was calculated by comparing with specific refrigerator capacity depending on the pressure and flow rate of a refrigerant medium, helium. Simulations were performed to investigate the optimal values of the liquefaction flow rate and compression pressure, which aim for the peak refrigeration effect. Based on this, a liquefaction system can be selected in consideration of the cycle configuration and the performance of the refrigerator.

유전자 알고리즘 PSGA를 이용한 복합재료 헬리콥터 블레이드 최적 구조설계 (Optimal Structural Design of Composite Helicopter Blades using a Genetic Algorithm-based Optimizer PSGA)

  • 장세훈;정성남
    • Composites Research
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    • 제35권5호
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    • pp.340-346
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    • 2022
  • 본 연구에서는 복합재료 블레이드에 대한 최적 구조설계 프레임워크를 구성하고, 이를 헬리콥터 블레이드에 적용하여 최적 구조설계를 수행하였다. 단면 형상의 경우 C형 및 D형 스파를 선택할 수 있게 구성하였으며, 최적설계 프레임워크는 유전자 알고리즘과 입자 군집 최적화 알고리즘을 결합한 PSGA를 활용하였다. 단면의 기하학적 모델링은 B-spline을 이용하여 구현하였고, 유한요소 모델 생성 프로그램 Gmsh를 통해 단면 유한요소모델을 만든 뒤 단면 해석 프로그램인 Ksec2D를 사용하여 구조해석 결과를 도출하였다. 본 최적설계 프레임워크를 HART II 블레이드에 적용하여 최적 구조설계를 수행한 결과, C형 스파 모델은 기준 형상 대비 무게 7.39%, D형 스파 모델은 6.65% 감소하였으며, 이때 전단중심은 모두 공력중심과 인접한(5% 이내) 결과를 도출하였다. 본 연구를 통해 일반적인 헬리콥터 블레이드의 단면에 적용할 수 있는 최적 구조설계 프레임워크의 유효성을 확인하였다.

3 MWth 급 매체순환연소 시스템의 운전변수 변화에 따른 성능 예측 (Performance Prediction of 3 MWth Chemical Looping Combustion System with Change of Operating Variables)

  • 류호정;남형석;황병욱;김하나;원유섭;김대욱;김동원;이규화;전명훈;백점인
    • 한국수소및신에너지학회논문집
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    • 제33권4호
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    • pp.419-429
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    • 2022
  • Effects of operating variables on temperature profile and performance of 3 MWth chemical looping combustion system were estimated by mass and energy balance analysis based on configuration and dimension of the system determined by design tool. Air reactor gas velocity, fuel reactor gas velocity, solid circulation rate, and solid input percentage to fluidized bed heat exchanger were considered as representative operating variables. Overall heat output and oxygen concentration in the exhaust gas from the air reactor increased but temperature difference decreased as air reactor gas velocity increased. Overall heat output, required solid circulation rate, and temperature difference increased as fuel reactor gas velocity increased. However, overall heat output and temperature difference decreased as solid circulation rate increased. Temperature difference decreased as solid circulation rate through the fluidized bed heat exchanger increased. Effect of each variables on temperature profile and performance can be determined and these results will be helpful to determine operating range of each variable.