• Title/Summary/Keyword: management agent

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Characteristics of Viral Endothelial Cell Necrosis of Eel (VECNE) from Culturing Eel (Anguilla japonica, Anguilla bicolar) in Korea (국내 양식산 뱀장어(Anguilla japonica, Anguilla bicolar)에서 발생하는 바이러스성내피세포괴사증(VECNE)의 감염 특성)

  • Kim, Su Mi;Ko, Sang Mu;Jin, Ji Hye;Seo, Jung Soo;Lee, Nam Sil;Kim, Young Suk;Gu, Jeong Hui;Bae, Yu Ri
    • Korean Journal of Ichthyology
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    • v.30 no.4
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    • pp.185-193
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    • 2018
  • From 2017 to 2018, the disease has been monitored at four culturing eel farms in Incheon and Gyeonggi region in Korea. As a result, diseases with gill congestion frequently occurred. This disease occurred regardless of size of eel, but the frequency and cumulative mortality were high in eels within 3 months after stocking. The infected fish showed pathological histopathological features such as intense congestion and dilation in the central venous sinus (CVS) of gill filaments and hemorrhages in liver and kidney. Hexagonal viral particles measuring about 70 nm in diameter was observed in nuclei and cytoplasm of gill vascular endothelial cells. Molecular biologic diagnosis by both PCR and genetic analysis has been revealed that the causative agent of this disease is Japanese eel endothelial cells-infecting virus (JEECV), the cause of viral endothelial cell necrosis of eel (VECNE), which is mainly reported in Japan. This study is the first report on the characteristics of JEECV and VECNE infection in domestic eel farms.

Study on the Tensile Strength of Virgin Hair by High-Density Oxidative Dye Application (버진 헤어(Virgin hair)의 고명도(高明渡) 산화염모제 시술에 따른 모발 인장강도 연구)

  • Lim, Sun-Nye;Park, Jang-Soon
    • Journal of Digital Convergence
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    • v.17 no.8
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    • pp.447-452
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    • 2019
  • Modern people are investing a lot of time and economically in their appearance as a means of expressing their aesthetic desires. They have a lot of hair dyes that make up most of their appearance, but their hair damage is serious. Especially, they use hair dyes which are very popular among the hair cosmetics that make up most of their appearance, but their hair damage is serious. The purpose of this study is to investigate the hair tensile strength of hair with oxidative hair dye to induce styling while minimizing hair damage. The results showed that the Max. load, Max. stress, Max. elongation, break load, break stress, break elongation, maximum modulus and tangential modulus according to evaluation interval were significantly different between control and 8N-10N experimental groups. The maximum modulus and tangential modulus for the strain interval did not show tendency to increase or decrease constantly, although there was a difference between the control and experimental group. Therefore this study was conducted to investigate the correlation between hair loss and hair damage through the treatment of high grade oxidative hair dye, which is widely used in ield of industry. We want to provide application data.

Extracorporeal Life Support in Acute Poisoning (급성 중독에서 체외순환보조장치의 적용)

  • Lee, Si Jin;Han, Gap Su;Lee, Eui Jung;Kim, Do Hyun;Park, Kyoung Yae;Lee, Ji Young;Kim, Su Jin;Lee, Sung Woo
    • Journal of The Korean Society of Clinical Toxicology
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    • v.16 no.2
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    • pp.86-92
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    • 2018
  • Purpose: Cardiovascular or respiratory complications of acute intoxication are the most common causes of mortality. Advanced cardiac life support (ACLS) or specific antidotes help manage these cardiac or respiratory complications in acute intoxication. On the other hand, some cases do not respond to ACLS or antidotes and they require some special treatment, such as extracorporeal life support (ECLS). ECLS will provide the chance of recovery from acute intoxication. This study examined the optimal timing of ECLS in acute intoxication cases. Methods: This paper is a brief report of a case series about ECLS in acute poisoning. The cases of ECLS were reviewed and the effects of ECLS on the blood pressure and serum lactate level of the patients were analyzed. Results: A total of four cases were reviewed; three of them were antihypertensive agent-induced shock, and one was respiratory failure after the inhalation of acid. The time range of ECLS application was 4.8-23.5 hours after toxic exposure. The causes of ECLS implementation were one for recurrent cardiac arrest, two for shock that did not respond to ACLS, and one for respiratory failure that did not respond to mechanical ventilator support. Three patients showed an improvement in blood pressure and serum lactate level and were discharged alive. In case 1, ECLS was stared at 23.5 hours post toxic exposure; the patient died due to refractory shock and multiple organ failure. Conclusion: The specific management of ECLS should be considered when a patient with acute intoxication does not recovery from shock or respiratory failure despite ACLS, antidote therapies, or mechanical ventilator support. ECLS improved the hemodynamic and ventilator condition in complicated poisoned patients. The early application of ECLS may improve the tissue perfusion state and outcomes of these patients before the toxic damage becomes irreversible.

Effects of Heterodera trifolii on Fusarium wilt disease in radish plants (클로버씨스트선충이 무시들음병 발병에 미치는 효과)

  • Ko, Hyoung-Rai;Park, Eun-Hyeong;Kang, Eun-Hye;Choi, Hyo-Won;Lee, Youngkee;Kim, Jeomsoon;Hong, Sung Kee
    • Korean Journal of Environmental Biology
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    • v.39 no.1
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    • pp.1-5
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    • 2021
  • Radish is one of the major vegetable crops and has been damaged economically by the causal agent of Fusarium wilt disease, Fusarium oxysporum f. sp. raphani (FO) in the highlands of Gangwon province, Korea. Recently, clover cyst nematode, Heterodera trifolii(HT), occurred in highland of Jeongseon area and poses a threat to radish plants. The nematodes, besides causing direct damage to radish plants, possess the capability to synergize with other plant pathogens, leading to the development of a disease complex. The aim of this study was to investigate the interaction between FO and HT in radish plants. The length of plants co-infected with both FO and HT was shorter than that of plants infected with FO alone, but there was no statistically significant difference. However, the disease severity was much higher in the plants co-infected with both FO and HT(1.60±0.97) compared to FO alone(0.20±0.42)(df=3, F=10.17, p<0.001). Disease incidence was also about two-fold higher in plants co-infected with both FO and HT (80%) compared to FO alone (44%). These results suggested that the clover cyst nematode should be considered in the management of Fusarium wilt disease in the highlands of Gangwon province.

A Study on the Activation Plan for Professional Sport League through Exploration of Inducing Factors of Match Fixing (승부조작 유발요인 탐색을 통한 프로스포츠 활성화 방안)

  • Bang, Shin-Woong;Park, In-Sil;Kim, Wook-Ki
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.3
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    • pp.153-170
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    • 2021
  • This study was attempted to derive strategic implications for activating professional sports by conducting in-depth interviews with professional sports officials such as players, teams, federations, agencies, etc., by searching for factors that cause match fixing and deriving preventive strategies based on them. Eight people with more than 3 years of experience working in professional sports were selected using the snowball sampling technique. Data were collected and analyzed by applying a semi-structured in-depth interview method for them. As a result of the analysis, five core categories (the learning effect from the cartel for entering university, the culture learned in a camp training, the manifestation of the latent learning effect, the negative effect of the human network, the personal disposition) were derived as factors causing match-fixing. As for the strategy to prevent match fixing, first, improving the college entrance examination system oriented on individual capability, second, improving the education system for student athlete, third, establishing a prevention system, fourth, continuing education, fifth, and activating the agent system as the core categories. Implications for the derived research results and future research directions were discussed.

Thermal Properties of Corn-Starch Filled Biodegradable Polymer Bio-Composites (옥수수 전분을 충전제로 첨가한 생분해성 고분자 복합재료의 열적성질)

  • Kim, Hee-Soo;Yang, Han-Seung;Kim, Hyun-Joong;Lee, Young-Kyu;Park, Hee-Jun
    • Journal of the Korean Wood Science and Technology
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    • v.32 no.5
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    • pp.29-38
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    • 2004
  • In this study, we investigated the thermal properties of corn-starch filled polybutylene succinate-adipate (PBS-AD) bio-composites. Thermal analysis (TA) is used to describe the analytical method for measuring the chemical property and weight loss of composite materials as a function of temperature. The thermal stability of corn-starch was lower than that of pure PBS-AD. As corn-starch loading increased, the thermal stability and degradation temperature of the bio-composites decreased and the ash content increased. It can be seen that the degree of compatibility and interfacial adhesion of the bio-composites decreased because of the increasing mixing ratio of the corn-starch. As the content of corn-starch increased, there was no significant change in the glass transition temperature (Tg) and the melting temperature (Tm) for the bio-composites. The storage modulus (E') and loss modulus (E") of the corn-starch flour filled PBS-AD bio-composites were higher than those of PBS-AD, because of the incorporation of corn-starch increased the stiffness of the bio-composites. At higher temperatures, the decreased storage modulus (E') of bio-composites was due to the increased polymer chain mobility of the matrix polymer. From these results, we can expect that corn-starch has potential as a reinforcing filler for bio-composites. Furthermore, we recommend using a coupling agent to improve the interfacial adhesion between corn-starch and biodegradable polymer.

The anti-inflammatory effect of Lithospermum Erythrorhizon on lipopolysaccharide - induced inflammatory response in RAW 264.7 cells (LPS로 유도한 RAW 264.7 세포의 염증반응에서 자초(紫草)의 항염증 효과)

  • Choi, Sun-Bok;Bae, Gi-Sang;Jo, Il-Joo;Park, Kyoung-Chel;Seo, Seung-Hee;Kim, Dong-Goo;Shin, Joon-Yeon;Gwak, Tae-Sin;Lee, Jung-Hyun;Lee, Guem-San;Park, Sung-Joo;Song, Ho-Joon
    • The Korea Journal of Herbology
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    • v.28 no.2
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    • pp.67-73
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    • 2013
  • Objective : Lithospermum Erythrorhizon (LE) has been used as an anti-bacterial and anti-inflammatory agent. However, it is unclear that LE aqueous extract could show the anti-inflammatory effects in RAW 264.7cells. The purpose of this study was to investigate the anti-inflammatory effect of aqueous extract from LE on lipopolysaccharide (LPS) - induced inflammatory response. Methods : To measure out the cytotoxicity of LE, we performed the MTT assay. To evaluate the anti-inflammatory effects of LE, we examined the inflammatory mediators such as nitric oxide (NO), prostaglandin E2 ($PGE_2$) and pro-inflammatory cytokines (tumor necrosis factor (TNF)-${\alpha}$, interleukin, (IL)-$1{\beta}$ and (IL)-6) on RAW 264.7 cells. We also examined molecular mechanisms such as mitogen-activated protein kinases (MAPKs) and nuclear factor-B (NF-${\kappa}B$) activation by western blot. Results : Aqueous Extract from LE itself did not have any cytotoxic effect in RAW 264.7 cells. Aqueous extract from LE inhibited LPS-induced productions of inflammatory mediators such as NO, $PGE_2$, and pro-inflammatory cytokines including TNF-${\alpha}$, IL-$1{\beta}$ and IL-6 in RAW 264.7cells. In addition, LE inhibited the phosphorylation of p38 kinases (p38), c-Jun $NH_2$-terminal kinase (JNK), and NF-${\kappa}B$ activation in RAW 264.7 cells. Conclusion : LE down-regulated LPS-induced production of inflammatory mediators through the inhibition of p38, JNK and NF-${\kappa}B$ activation. Taken together, these results could provide the evidence for the anti-inflammatory effects of LE. Therefore, LE may be a novel target in the management of inflammation and help to support a potential strategy for prevention and therapy of inflammatory diseases.

Priority Determination of the Projects for Ecological Restoration of the Stream : Case Study for Han River Estuary (생태하천 복원사업 우선순위 선정에 대한 연구: 한강하구를 중심으로)

  • Seonuk Baek;Junhak Lee;Seungmin Lee;Haneul Lee;Hung Soo Kim;Soojun Kim
    • Journal of Wetlands Research
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    • v.25 no.1
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    • pp.64-73
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    • 2023
  • Before 2022, there was a lot of confusion in the process of planning and implementing the projects for ecological restoration of the stream due to dualization the principal agent of stream management. Because the Ministry of Environment took charge of the project in 2022, securing the health of aquatic ecosystem of stream became an essential factor in the project. Therefore, in this study, the streams that require the project for ecological restoration was selected in Han River estuary, where it is essential to secure the health of the stream aquatic ecosystem as blackish water zone and Ramsar wetland are located. Physical, chemical, spatial/humanistic, health of aquatic ecosystems evaluation indexes were calculated based on the detailed facts and figures of the project for ecological restoration of the stream in the beginning. Ranking, re-scaling, z-score, and t-score normalization methods were applied to the calculated evaluation index, and the values were compared and analyzed. After that, the entropy weight method was applied to each evaluation index. Through this process, the streams(Mokgamcheon, Anyangcheon etc.) that require the project for ecological restoration were selected for the purpose of securing the health of the aquatic ecosystem in Han River estuary. The result of this study can be used as basic research data in the process of selecting the priority determination of the projects for ecological restoration of the stream.

Success Strategies for In-Bound City Tourism - Focused on Daegu Metropolitan City - (인바운드 도시관광을 위한 성공전략: 대구광역시를 중심으로)

  • Kim, Dong-Joon;Park, Shin-Il
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.2
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    • pp.13-25
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    • 2019
  • This study conducted individual in-depth interviews of tourists from Taiwan, Hong Kong and Thailand who visited Daegu. According to the analysis, Taiwan's target audience conducted an interview at the Chimac Festival in July 2018 at Duryu Park and was a university student as an individual female tourist. She got the information through SNS. The accommodation was guest house and medium and low cost hotel. The main tourist attractions included Seomun Market Night Market, Eworld and Dongseongno. The meals were Anjirang Gopchang and Galbijim in Dongin-dong. Next, the Hong Kong tourist interview was held in May 2018 at the Kwandeung Festival in Duryu Park, and was an individual tourist as a man. Lastly, an interview with a Thai tourist was held in April 2018 at the Donghwa Temple Cherry Blossom Festival in Palgongsan Mountain, and he purchased a travel agent product as a man. Participants of the tour in Daegu were interested in unusual experiences such as beauty, wedding, theme parks, and restaurants that are unique to Korea. What was disappointing was that there were not enough shopping facilities, such as duty free shops, and that the table in the restaurant was inconvenient, and that there were not enough signboards by language for foreigners.

A Study on the Use of Contrast Agent and the Improvement of Body Part Classification Performance through Deep Learning-Based CT Scan Reconstruction (딥러닝 기반 CT 스캔 재구성을 통한 조영제 사용 및 신체 부위 분류 성능 향상 연구)

  • Seongwon Na;Yousun Ko;Kyung Won Kim
    • Journal of Broadcast Engineering
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    • v.28 no.3
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    • pp.293-301
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    • 2023
  • Unstandardized medical data collection and management are still being conducted manually, and studies are being conducted to classify CT data using deep learning to solve this problem. However, most studies are developing models based only on the axial plane, which is a basic CT slice. Because CT images depict only human structures unlike general images, reconstructing CT scans alone can provide richer physical features. This study seeks to find ways to achieve higher performance through various methods of converting CT scan to 2D as well as axial planes. The training used 1042 CT scans from five body parts and collected 179 test sets and 448 with external datasets for model evaluation. To develop a deep learning model, we used InceptionResNetV2 pre-trained with ImageNet as a backbone and re-trained the entire layer of the model. As a result of the experiment, the reconstruction data model achieved 99.33% in body part classification, 1.12% higher than the axial model, and the axial model was higher only in brain and neck in contrast classification. In conclusion, it was possible to achieve more accurate performance when learning with data that shows better anatomical features than when trained with axial slice alone.