• Childhood Kidney Diseases
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• 제1권2호
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• pp.189-194
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• 1997

Oligomeganephronia is a rare congenital form of bilateral renal hypoplasia histologically characterized by reduction in number and hypertrophy of nephrons. Clinically, this condition is presented in early infancy with vomiting, polyuria, polydipsia and dehydration. The problems are readily corrected, but slowly progressive renal failure follows accompanied by failure to thrive, short stature, and renal osteodystrophy. We experienced three cases of oligomeganephronia. Case 1. : A 3 2/12 years old female child was incidentally diagnosed as renal failure at age of 2 months when she was hospitalized due to pneumonia. She had open renal biopsy and was diagnosed as bilateral dysplastic kidney. On OPD follow-up, she progressed to end-stage renal failure (BUN/Cr 114/4.6 mg/dl) and had renal transplantation. The specimen was shrunk remarkably and light microscopy showed oligomeganephronia. Case 2. : A 14 8/12 years old female child with proteinuria was detected in an annual urine screening program for school children, she was diagnosed as renal failure (BUN/Cr 33.9/4.1 mg/dl), and had $5{\times}4{\times}3\;cm$ sized mass on abdominal CT scan. She had renal biopsy, and the specimen showed oligomeganephronia. She had hemodialysis for six months, and renal transplantation along with bilateral nephrectomy was performed. Case 3. : A 14 8/12 years old male child was diagnosed having chronic nephritis and chronic renal failure at 3 years old, progressed to end-stage renal failure (BUN/Cr 87/9.6 mg/dl) on OPD follow-up, and had a rephrectomy and renal transplantation. The biopsy specimen showed oligomeganephronic hypoplasia, secondary focal segmental glomerolosclerosis, and chronic interstitial nephritis. We report 3 cases of oligomeganephronia that progressed to end-stage renal failure and had successful renal transplantation with a brief review of related literatures.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제11권1호
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• pp.50-62
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• 1989

저자는 1982년 1월부터 1987년 12월까지 대구시내 주의료기관인 5개 종합병원에 입원가료한 바 있는 하악골 골절환자 677명을 대상으로 임상적 연구를 시행한 바 다음과 같은 결과를 얻었다. 발생빈도에 있어서 연도별로는 약간의 증가추세에 있었고, 월별로는 5월과 9월에 호발하였고 지역별로는 대구시(55.7%)가 많았으며 대도시 (63.0%)에서 다소 높았다. 연령별 및 성별에서 20대(38.3%)에서 가장 호발하였으며 10대(18.5%), 30대 (18.0%)의 순으로 나타났으며 남녀비는 4.64 : 1로서 남자에게서 호발하였다. 원인별로 볼때 구타(31.5%), 교통사고 (29.5%)와 추락(15.2%), 전도(15.1%)로 많은 비중을 나타내었으며,별로 보면 20-40시 사이에 구타가 가장 많았다. 골절부위별로는 하악골 단독골절이 95.5%였으며 중안면골 골절이 동반된 경우가 4.5%였으며 골절 부위 수는 총 1,033개로서 1인당 평균 1.53개였으며 정중부(39.8%), 우각부(25.2%), 과두부(22.7%)의 순이었으며 정중부를 제외한 좌우측 비교에서 좌측이 364례로서 우측의 257례보다 많았다. 수상후 24시간이내에 전체의 62.9%가 내원하였으며, 1차 진료기관을 거친 경우가 42.4%였으며 유형별로는 일반의원(44.6%), 일반병원(27.9%) 및 치과의원(25.4%)의 순으로 나타났다. 처치내용별로는 관혈적정복수술이 전체의 55.0%를 차지하였고 37.2%는 비관혈적 정복수술을 받았으며, 소아에서는 주로 비관혈적 정복수술이 50.6%를 차지하였다.

• Clinical and Experimental Pediatrics
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• 제60권3호
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• pp.86-93
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• 2017

Purpose: To evaluate the clinical spectrum of posttransplantation lymphoproliferative disorder (PTLD) after solid organ transplantation (SOT) in children. Methods: We retrospectively reviewed the medical records of 18 patients with PTLD who underwent liver (LT) or kidney transplantation (KT) between January 1995 and December 2014 in Seoul National University Children's Hospital. Results: Eighteen patients (3.9% of pediatric SOTs; LT:KT, 11:7; male to female, 9:9) were diagnosed as having PTLD over the last 2 decades (4.8% for LT and 2.9% for KT). PTLD usually presented with fever or gastrointestinal symptoms in a median period of 7 months after SOT. Eight cases had malignant lesions, and all the patients except one had evidence of Epstein-Barr virus (EBV) involvement, assessed by using in situ hybridization of tumor tissue or EBV viral load quantitation of blood. Remission was achieved in all patients with reduction of immunosuppression and/or rituximab therapy or chemotherapy, although 1 patient had allograft kidney loss and another died from complications of chemotherapy. The first case of PTLD was encountered after the introduction of tacrolimus for pediatric SOT in 2003. The recent increase in PTLD incidence in KT coincided with modification of clinical practice since 2012 to increase the tacrolimus trough level. Conclusion: While the outcome was favorable in that all patients achieved complete remission, some patients still had allograft loss or mortality. To prevent PTLD and improve its outcome, monitoring for EBV infection is essential, which would lead to appropriate modification of immunosuppression and enhanced surveillance for PTLD.

• Pediatric Infection and Vaccine
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• 제15권2호
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• pp.188-194
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• 2008

목 적 : 가와사끼병의 재발에 있어서의 임상양상 및 관련된 인자를 찾아보고자 하였다 방 법 : 2004년 1월부터 2007년 12월까지 세브란스 어린이병원 소아청소년과에서 가와사끼병으로 2회이상 치료받은 환아 20명을 대상으로 하여 초기 발병시와 재발시의 입원기록을 후향적으로 비교분석 하였다. 결 과 : 재발한 가와사끼병 환자 20명의 남여 성비는 1.2:1이었으며 평균연령은 $37.2{\pm}19.9$개월이었고, 재발 간격은 평균 3.3개월이었다. 첫 발병시보다 재발시에 발열 기간이 더 짧았고 발진이 적었으나 혈액학적 소견, 치료 결과 및 합병증은 차이가 없었다. 재발시 3명(15%)에서 정맥용 면역글로불린 초기치료에 반응하지 않았다. 재발 하지 않은 그룹에 비해 재발한 그룹에서 적혈구 침강속도 수치가 더 높았다. 결 론 : 가와사끼병은 재발하는 경우에는 비전형적 가와사끼병으로 표현될 수 있으므로 소아청소년과 의사는 이런 특징을 유념하여 진단과 치료를 수행하여야 할 것이다.

• 한국생활과학회지
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• 제16권4호
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• pp.849-854
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• 2007

Body fat proportion is a major issue in health. The prevalence of obesity in childhood has been increasing on thesedays. A series of indirect estimates of body fat have been developed. There are hydrodensitometry, BIA and anthropometry equation for body fat. Hydrodensitometry has been regarded as a common criterion method. BIA made it possible to analyze body fat mass more related to hydrodensitometry than anthropometry. The purpose of this unvestigation were to compare body fat and other body composition between boys & girls and to know which anthropometry equation for body fat was most closely associated with BIA in boys & girls respectively. The subjects were 148 4th grade elementary school students(male:70, female:78). They underwent BIA(InBody 3.0, Biospace Korea)to determine body fat and other body composition. Anthropometric measurements were taken of height, weight, skinfolds and circumferences. The results obtained are summarized as follow: 1) Weight, BMI and Rohrer index were $39.9{\pm}7.2kg$, $20.5{\pm}8.0$, $138.2{\pm}17.0$ for boys and $35.9{\pm}6.7kg$, $18.2{\pm}2.6$, $96.6{\pm}13.6$ for girls. 2) Total body fat and percent body fat determined by BIA were $10.3{\pm}4.3kg$, $25.4{\pm}6.6%$ for the boys group and $9.3{\pm}3.8kg$, $25.1{\pm}6.0%$ for girls. 3) Mean triceps skinfold thickness was $20.5{\pm}6.1mm$ in boys, $17.0{\pm}5.1mm$ in girls and mean WHR was $0.88{\pm}0.4$ in bodys, $0.82{\pm}0.4$ in female and the values were significantly different by sex. 4) Correlational nanlyses showed that estimation of body fat by BIA measurement seemed to be closely associated with Rohere index(boys r=0.854, girls r=0.909). Kim's equation was highly correlated with the body fat in girls(r=0.910) but less correlated in boys(r=0.710). We need to develop specific anthropometric equations based on age and sex to determine body fat for children.

• 대한소아치과학회지
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• 제46권2호
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• pp.147-157
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• 2019

이 연구는 상악 측절치 선천결손을 보이는 초기 혼합치열기 아동의 골격 및 치아치조 특성을 평가하고자 하였다. 부산대학교 치과병원 소아치과에 교정진단 및 치료를 목적으로 내원한 초기 혼합치열기의 상, 하악 유견치가 모두 존재하는 아동 중, 상악 측절치를 제외한 나머지 치아 결손이 없는 38명의 상악 측절치 결손군과 대상 기준을 만족시키는 동일한 치령의 대조군 38명을 선정하였다. 각 군의 측모 두부계측 방사선분석과 모형 분석의 측정값을 비교하여 상악 측절치 결손군의 골격 및 치아치조 특성을 평가하였다. 성별에 따른 결손의 총 비율은 남아가 더 높았고 편측 결손군에서는 남아의 비율이 더 높았지만 양측 결손군에서는 여아의 비율이 더 높았다. 모형 분석에서 결손군은 대조군에 비해 상악 전방부 폭경 대 장경 비가 크게 나타났고(p = 0.003), 총악궁둘레는 작게 나타났다(p = 0.04). 측모 두부계측 방사선분석 결과, 골격 및 치아적 측면에서는 유의한 차이가 없었고, 연조직 외형에서 결손군이 대조군에 비해 nasolabial angle이 큰 값을 나타냈다(p = 0.039). 상악 측절치 결손 아동의 골격 및 치아치조 특징에 유념하여 뚜렷한 안모 및 기능 이상을 보이기 이전에 조기 진단 후 적절한 관리를 통해 기능적 결함의 가능성을 최소화 시키는 것이 추천된다.

• 한국과학교육학회지
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• 제14권1호
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• pp.58-69
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• 1994

In this study, with the problem of "What is the desirable illustrations?", the problem points of the existing textbooks were analyzed, and the opinions of experts concerning desirable illustrations were examined through questionaire survey, and by developing 'Analysis Framework of Illustrations', and Korean-Japanese 'science' textbooks were analyzed and compared with. The conclusions for the direction of korean 'science' textbooks are summarized as follows : 1) The numbers of korean illustrations should be more about two than one of per one page of the existing textbooks. 2) The korean illustrations for the 6th grade should be more largely inserted. 3) The more econmic space utilizing measure should be groped for looking at from the such side. 4) Though the kinds of Korean illustrations are mostly composed of photographs, pictures, illustrations, cartoons, etc. should be positively utilized. and the shapes of photographs should be diversified by such as square, round shape,omissions of background and others. 5) The distribution of players by sex should be considered envenly for male and female from the ascendency of male (1.5: 1). 6) It was found that it is desirable for the formation of role of illustrations of 20% for motive inducement, 45% for guidance for experimentation, 30% for presentation of data, and 5% for presentation of the results of experimentation. 7) The illustrations for guidance for experimentation should present important stages of experimentation process regardless the number of illustration. 8) It would be advantageous for motive induction to find the subject matters as possible as from the children's close actual life. 9) It is necessary to induce more freely method in utilizing Printing plate for inserting illustrations. 10) It is the result of research that the existing Korean textbooks are not suitable in inducing interest, and the positive strategy to induce interest is demanded. 11) It is required to select their location freely in accordance with the content regardless the. 12) In order to develop such illustrations, it is required to cultivate expert illustrators, and more economic investment is required for development of illustrations. The emphasis matters of revision of the 6th educational process of 'Inducement of study motive and emphasis on interest' is the change of presenting form and method of illustrations, which is expected to be rewarded with much good fruits.

• Childhood Kidney Diseases
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• 제18권2호
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• pp.98-105
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• 2014

목적: Nafamostat mesilate는 출혈성 경향이 있는 성인 환자에서 지속적 신대체 요법시 항응고제로 사용되고 있지만 소아에서의 경험은 잘 알려지지 않았다. 본 연구는 출혈 성향이 높은 소아에서 지속적 신대체 요법을 시행하는 경우에 항응고제로서 Nafamostat mesilate의 용량, 효과, 및 안전성에 대하여 알아보기 위해 수행하였다. 방법: 2011년 1월부터 2013년 10월까지 최소 24시간이상 지속적신대체요법을 받은 40명의 소아환자들을 대상으로 하여 의무기록을 후향적으로 분석하였다. 환자들은 출혈 위험군(그룹 1: 항응고제 사용 안함, 그룹 2: 항응고제로 Nafamostat mesilate 사용)과 출혈 위험이 없는 군(그룹 3: 항응고제로 헤파린 사용)으로 분류하였다. 결과: 40명의 환자 중에서 남아는 25명 여아는 15명 이었으며 평균 나이는 $8.2{\pm}6.6$세 이었다. 지속적신대체요법의 평균 시간은 13일 이었다. 평균 혈액 필터 수명은 그룹 1에서는 39.3시간 이었고, 그룹 3에서는 11.3시간이었다. 그룹 2에서는 Nafamostat mesilate 사용 전에는 7.5시간 이었으나 Nafamostat mesilate 사용 후에는 27.4시간으로 연장되었으며 통계학적으로 유의하였다(P=0.001). 평균 혈액 필터 수명은 Nafamostat mesilate을 사용한 그룹에서는 헤파린을 사용한 그룹보다 통계적으로 의미 있게 연장되었다(P=0.018). Nafamostat mesilate 사용한 군에서 의미있는 출혈이 동반되지는 않았다. 결론: Nafamostat mesilate은 출혈 성향이 높은 소아에서 지속적 신대체 요법을 시행하는 경우에 헤파린을 대체해서 사용될 수 있는 항응고제로 생각된다.

• 한국보건간호학회지
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• 제8권2호
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• pp.101-113
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• 1994

Maternity means all the women who are capable to conceive. In the aspect of health and medical care. however. it means the women who are now in pregnancy or have already given birth to a baby or are in a period of being recoverd from physiological changes occurred by pregnancy. According to the rapidly changing social structure. both the Quality and Quantity of the capacity of childbirth experienced by women are changing. Our society. having established a great economical growth by virtue of the highly developing and growing industrialization and urbanization. stimulates the women's advance into society and thereby increasing the number of employed women. When the women's participation in society is increased. their age of marriage is also affected. Which means there are a decrease of the capacity of childbirth in terms of quantity and a trend for women to have less children and to deliver a baby in their old age in terms of quality. On the contrary. since the number of multipara who want to have a baby in their old age is increasing. as a counter functional effect to the political project of decrease of a birth rate. concern has been focussed on childbirth in old age in the present study. And also such kind of the childbirth may be danger to the health of both mother and baby. Therefore the present study intended to provide some basic data of health education in the part of the health management of both mother and baby in the general hospital. based on understanding the realities of childbirth in. old age and things related to them. To achieve such a purpose of the present study. an analytical study by means of SPSS. was done using the data of 269 clinical records on both the newborn .babies and their mothers who had been supported by public general hospitals located in Seoul for 3 years from Jan. 1. 1991 to Dec. 31. 1993. Some significant results from the analytic study are as follows: 1. It appeared that the average age of normal. natural delivery was 33.8 years old and the average age of delivery through the cesarean operation was 35.4 years old. 2. It appeared that danger factors to childbirth women were types of the delivery and placental extrusion and danger factors to newborn babies are not so outstanding. 3. It appeared that the variables of the childbirth capacity which showed a significant difference according to each age group of women were the number of pregnancy. number of still birth, and number of existing children. That is. the age group of 'more than 35 years' had more frequency of experience In all 3 variables than the age group of 'less than 35 years'. 4. It appeared that the variables of the childbrith capacity which showed a significant difference a according to the sex of a newborn baby were number of pregnancy, number of still birth, and number of existing children. That is, the age group of 'more than 35 years' had more frequency of experience in all 3 variables than the age group of 'less than 35 years'. 5. It appeared that the health index of newborn babies which showed a significant difference was only 5 minute APGAR. That is, the health index 9.46 in the age group of 'more than 35 years' was less than an index of 9.72 in the age group of 'less than 35 years'. 6. Since a counter correlation of -0.10, as Pearson Correlation Coefficient, was showed between the age of childbirth mothers and the weight of newborn babies, it indicated that the higher age of childbirth woman, the lesser the weight of newborn baby. 7. It appeared that the number of women who had confirmed the sex of their baby before their delivery were 45 women, $67.2\%$ of total 67 women who had delivered a baby. and the expected sex by women in childbed was male with $73.1\%$ of total childbirth women expecting male birth and with their expression of feeling of female delivery. very regretful' by $39.3\%$ of total childbirth women. The results as shown above may indicate that instead of the possibility of danger to both the mother delivering a baby in old age and the baby delivered, the expectation of getting a son motivates childbirth in old age. As a conclusion, in a dimension of general hospital as well as national reform. it is required that a program of health education for childbirth in late maternal age have to be developed in the part of the health management of both mother and baby in the near future.

• 초등상담연구
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• 제11권2호
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• pp.153-169
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• 2012

초등학생의 또래관계가 발달에 미치는 영향을 알아보기 위한 방법으로 먼저, 또래관계를 어떻게 소집단 형태로 묶는(grouping) 것이 가장 합리적인 방법인가를 찾아내는 것이 연구의 목적이었다. 이에 따라 지각자료와 심리적 선호도 자료에 의한 또래관계 소집단 분류의 방법 간에는 서로 어떤 차이가 있는지를 알아보는 것이 연구문제로 설정되었다. 연구 대상은 부산과 울산의 초등학교 중학년인 3-4학년 아동 가운데 남자는 3학년, 여자는 4학년의 2학급이었다. 연구 문제를 검증하기 위한 질문지는 두 가지로 지각 자료 질문지와 심리적 선호도 질문지였다. 지각 자료는 공유인접수를 바탕으로 상관관계의 값을 적용하여 또래관계의 소집단으로 분류 되었으며, 선호도 자료는 이자관계를 확장하여 삼자관계 이상의 소집단으로 또래관계를 분류하는 방법을 적용하였다. 본 연구의 결과, 여자 아동의 경우에는 지각 자료에 의한 소집단과 선호도 자료에 의한 소집단간에 매우 유사한 분류의 일치성이 나타났지만, 남자 아동의 경우에는 두 가지 분류 방법간에 분류의 차이가 나타났다. 이러한 결과로 볼 때, 남자 아동의 경우에는 개별 아동간의 심리적 불일치에도 불구하고 또래관계를 형성할 가능성이 있지만, 여자 아동의 경우에는 심리적으로 일치될 때 또래관계가 형성되는 것으로 확인되었다. 이러한 결과는 양성간의 또래관계 형성 과정이 다를 수 있음을 시사한다. 따라서 남자 아동의 또래관계를 합리적으로 분류하기 위한 후속연구로 담임 교사에 의한 소집단 분류, 지각 자료에 의한 소집단 분류, 선호도 자료에 의한 소집단 분류의 세 가지 분류 방법 간의 적합성에 대한 비교 작업이 수행될 필요성이 있었다.