• Title/Summary/Keyword: malaysia

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Conventional versus Doxorubicin-Eluting Beads Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma: a Tertiary Medical Centre Experience in Malaysia

  • Rahman, F Abdul;Naidu, J;Ngiu, CS;Yaakob, Y;Mohamed, Z;Othman, H;Jarmin, R;Elias, MH;Hamid, N Abdul;Mokhtar, N Mohd;Ali, RA Raja
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.8
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    • pp.4037-4041
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    • 2016
  • Background: Hepatocellular carcinoma (HCC) is a common cancer that is frequently diagnosed at an advanced stage. Transarterial chemoembolisation (TACE) is an effective palliative treatment for patients who are not eligible for curative treatment. The two main methods for performing TACE are conventional (c-TACE) or with drug eluting beads (DEB-TACE). We sought to compare survival rates and tumour response between patients undergoing c-TACE and DEB-TACE at our centre. Materials and Methods: A retrospective cohort study of patients undergoing either treatment was carried out from January 2009 to December 2014. Tumour response to the procedures was evaluated according to the modified Response Evaluation Criteria in Solid Tumors (mRECIST). Kaplan-Meier analysis was used to assess and compare the overall survival in the two groups. Results: A total of 79 patients were analysed (34 had c-TACE, 45 had DEB-TACE) with a median follow-up of 11.8 months. A total of 20 patients in the c-TACE group (80%) and 12 patients in the DEB-TACE group (44%) died during the follow up period. The median survival durations in the c-TACE and DEB-TACE groups were $4.9{\pm}3.2$ months and $8.3{\pm}2.0$ months respectively (p=0.008). There was no statistically significant difference noted among the two groups with respect to mRECIST criteria. Conclusions: DEB-TACE demonstrated a significant improvement in overall survival rates for patients with unresectable HCC when compared to c-TACE. It is a safe and promising approach and should potentially be considered as a standard of care in the management of unresectable HCC.

Identification of Cryptosporidium from Dairy Cattle in Pahang, Malaysia

  • Hisamuddin, Nur Hazirah;Hashim, Najat;Soffian, Sharmeen Nellisa;Amin, Mohd Hishammfariz Mohd;Wahab, Ridhwan Abdul;Mohammad, Mardhiah;Isa, Muhammad Lokman Md;Yusof, Afzan Mat
    • Parasites, Hosts and Diseases
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    • v.54 no.2
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    • pp.197-200
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    • 2016
  • Cryptosporidium, a protozoan parasite, can cause cryptosporidiosis which is a gastrointestinal disease that can infect humans and livestock. Cattle are the most common livestock that can be infected with this protozoan. This study was carried out to determine the prevalence of Cryptosporidium infection in cattle in Kuantan, Pahang, Malaysia and to find out the association between the occurrence of infection and 3 different ages of cattle (calves less than 1 year, yearling, and adult cattle). The samples were processed by using formol-ether concentration technique and stained by modified Ziehl Neelsen. The results showed that 15.9% (24/151) of cattle were positive for Cryptosporidium oocysts. The occurrence of Cryptosporidium in calves less than 1 year was the highest with the percentage of 20.0% (11/55) followed by yearling and adult cattle, with the percentage occurrence of 15.6 % (7/45) and 11.8% (6/51), respectively. There was no significant association between the occurrence and age of cattle and presence of diarrhea. Good management practices and proper hygiene management must be taken in order to reduce the infection. It is highly important to control the infection since infected cattle may serve as potential reservoirs of the infection to other animals and humans, especially animal handlers.

Stratifying Patients with Haematuria into High or Low Risk Groups for Bladder Cancer: a Novel Clinical Scoring System

  • Tan, Guan Hee;Shah, Shamsul Azhar;Ann, Ho Sue;Hemdan, Siti Nurhafizah;Shen, Lim Chun;Abdul Galib, Nurudin Al-Fahmi;Singam, Praveen;Kong, Ho Chee Christopher;Hong, Goh Eng;Bahadzor, Badrulhisham;Zainuddin, Zulkifli Md
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6327-6330
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    • 2013
  • Haematuria is a common presentation of bladder cancer and requires a full urologic evaluation. This study aimed to develop a scoring system capable of stratifying patients with haematuria into high or low risk groups for having bladder cancer to help clinicians decide which patients need more urgent assessment. This cross-sectional study included all adult patients referred for haematuria and subsequently undergoing full urological evaluation in the years 2001 to 2011. Risk factors with strong association with bladder cancer in the study population were used to design the scoring system. Accuracy was determined by the area under the receiver operating characteristic (ROC) curve. A total of 325 patients with haematuria were included, out of which 70 (21.5%) were diagnosed to have bladder cancer. Significant risk factors associated with bladder cancer were male gender, a history of cigarette smoking and the presence of gross haematuria. A scoring system using 4 clinical parameters as variables was created. The scores ranged between 6 to 14, and a score of 10 and above indicated high risk for having bladder cancer. It was found to have good accuracy with an area under the ROC curve of 80.4%, while the sensitivity and specificity were 90.0% and 55.7%, respectively. The scoring system designed in this study has the potential to help clinicians stratify patients who present with haematuria into high or low r isk for having bladder cancer. This will enable high-risk patients to undergo urologic assessment earlier.

Knowledge, Attitude and Behavior of Healthcare Providers towards Breast Cancer in Malaysia: a Systematic Review

  • Azeem, Eman;Gillani, Syed Wasif;Siddiqui, Ammar;HA, Al Shammary;Poh, Vinci;Sulaiman, Syed Azhar Syed;Baig, Mirza
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5233-5235
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    • 2015
  • Breast cancer is the most common cancer among women in Malaysia. Therefore, it is highly important for the public to be educated on breast cancer and to know the steps to detect it early on. Healthcare providers are in the prime position to provide such education to the public due to their high knowledge regarding health and their roles in healthcare. The present systematic review involved studies conducted in recent years to analyze the knowledge, attitudes and behavior of Malaysian healthcare providers regarding breast cancer, in attempts to obtain an overall picture of how well equipped our healthcare providers are to provide optimal breast cancer education, and to see their perceptions and actual involvement in said education. The systematic review was conducted via a primary search of various databases and journal websites, and a secondary search of references used by eligible studies. Criteria for eligibility included being published from the year 2008 till present, being conducted in Malaysia, and being written in the English language. A total of two studies were eligible for this review. Findings show that Malaysian future and current healthcare providers have moderate knowledge on breast cancer, have a positive towards involvement of breast cancer education, but have poor actual involvement.

Anthraquinones from Cell Suspension Culture of Morinda elliptica

  • Jasril, Jasril;Lajis, N.H.;Abdullah, M.A.;Ismail, N.H.;Ali, A.M.;Marziah, M.;Ariff, A.B.;Kitajima, M.;Takayama, H.;Aimi, N.
    • Natural Product Sciences
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    • v.6 no.1
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    • pp.40-43
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    • 2000
  • The chemical investigation on the cell suspension culture of Morinda elliptica L. yielded eight anthraquinones, two of which, anthragallol-1,2-dimethyl ether (3) and purpurin-1-methyl ether (4), have not been isolated from the original plant. Other compounds isolated include nordamnacanthal (1), alizarin-1-methyl ether (2), rubiadin (5), soranjidiol (6), $lucidin-{\omega}-methyl$ ether (7), and morindone (8). The structures of anthraquinones were established based on spectral studies.

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Predicting required licensed spectrum for the future considering big data growth

  • Shayea, Ibraheem;Rahman, Tharek Abd.;Azmi, Marwan Hadri;Han, Chua Tien;Arsad, Arsany
    • ETRI Journal
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    • v.41 no.2
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    • pp.224-234
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    • 2019
  • This paper proposes a new spectrum forecasting (SF) model to estimate the spectrum demands for future mobile broadband (MBB) services. The model requires five main input metrics, that is, the current available spectrum, site number growth, mobile data traffic growth, average network utilization, and spectrum efficiency growth. Using the proposed SF model, the future MBB spectrum demand for Malaysia in 2020 is forecasted based on the input market data of four major mobile telecommunication operators represented by A-D, which account for approximately 95% of the local mobile market share. Statistical data to generate the five input metrics were obtained from prominent agencies, such as the Malaysian Communications and Multimedia Commission, OpenSignal, Analysys Mason, GSMA, and Huawei. Our forecasting results indicate that by 2020, Malaysia would require approximately 307 MHz of additional spectrum to fulfill the enormous increase in mobile broadband data demands.

Malaysia's Flawed Democracy: A Stumbling Block Towards Becoming a First World Developed Nation

  • Juli Ooi
    • SUVANNABHUMI
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    • v.15 no.2
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    • pp.271-303
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    • 2023
  • In 1991, Malaysia, under the leadership of then-Prime Minister Mahathir Mohamad, launched an ambitious 30-year national development program known as Vision 2020. The goal of this program was to transform Malaysia into a First World developed nation by the year 2020. One of the aspirations of the program was to create a psychologically liberated, secure, ethical, and mature democratic society. Vision 2020 is a failure and Malaysia is still not a mature democracy. This article identifies four main areas that make up a flawed democracy practiced in Malaysia, and shows how they work against the country's aspirations to become a developed nation. The electoral system is rigged to help the incumbent remain in power. The widespread practices of money politics have become a curse to the country. The press and media organizations are restricted. Civil society activities are suppressed. As a result of these issues, Malaysia will not be able to achieve the status of a developed nation, lacking democratic accountability and inclusive institutions.

A Study of the Cultural Characteristics and Meanings of the Encounter between Malaysian Migration Policy and Korean Retirement Migration in Malaysia (말레이시아의 이민정책과 한국인 은퇴이주의 조우(遭遇))

  • Hong, Suk-Joon
    • The Journal of the Korea Contents Association
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    • v.16 no.4
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    • pp.555-568
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    • 2016
  • This study aims to examine the characteristics and meanings of the encounter between Malaysian migration policy and Korean retirement migration in contemporary Malaysia. For this purpose, I describe and analyze the features and implications of migration policy in Malaysia, and understand the cultural characteristics and meanings of migration policy, especially Malaysian migration policy in Malaysia, and examine and explore the characteristics and meanings of retirement migration, especially Korean retirement migration to Malaysia in contemporary Malaysia, in the socio-cultural context. The research outcomes of this study are followings. Firstly, because of the misunderstanding and misuse of MM2H(Malaysia My 2nd Home) program and Malaysian migration policy among Korean retirement migrants in contemporary Malaysia, Korean retirement migration in Malaysia cannot be regarded one of the appropiate and effective migration policy for Koreans. It has been utilized as an instrument of their children's education among Koreans in Malaysia. Secondly, in this regard, it has been increased the number of Koreans to return to Korea without any constructive results in their children's education and their successful retirement lives in Malaysia. It is noted to understand that Korean retirement migration to Malaysia is the movement and migration of the special forms of human migration or human exchange and cooperation in the socio-cultural context. The cultural characteristics and meanings of Korean retirement migration to Malaysia has been one of the important cultural phenomena between Korea and Malaysia in contemporary Malaysia. In this sense, it is expected that this study can be contributed to understand the cultural characteristics and meanings of the encounter and exchange between Malaysian migration policy and Korean retirement migration to Malaysia in contemporary Malaysia, and to enhance the exchange and cooperation between Korea and Malaysia through human exchange and migration, especially Korean retirement migration to Malaysia in contemporary Malaysia.

The First Report of Penicillium georgiense in Malaysia

  • Yee, Teh Li;Zakaria, Latiffah
    • Mycobiology
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    • v.42 no.3
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    • pp.274-278
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    • 2014
  • Penicillium georgiense was isolated from sandy beach soil from Batu Ferringhi beach, Penang Island, Malaysia. The identification was based on morphological characteristics and phylogenetic analysis of internal transcribed spacer regions and ${\beta}$-tubulin sequences. To the best of our knowledge, this is the first report of P. georgiense in Malaysia.

A Review of Ocean Wave Power Extraction; the primary interface

  • Nik, W.B. Wan;Muzathik, A.M.;Samo, K.B.;Ibrahim, M.Z.
    • International Journal of Fluid Machinery and Systems
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    • v.2 no.2
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    • pp.156-164
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    • 2009
  • This paper aims to describe the importance of data, data collection methods, parameters to estimate the potential of wave energy and environmental impacts. The technical and economical status in wave energy conversion is outlined. Power and energy efficiency relationships are discussed. Many different types of wave-energy converters have been detailed. The progress in wave energy conversion in Malaysia is reviewed.