• Title/Summary/Keyword: magnification process

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An Immunohistochemical Study of Tumor Angiogenesity in Follicular Thyroid Carcinoma (여포상 갑상선암종의 종양맥관형성도)

  • Chung Woong-Youn;Lee Mi-Kyung;Chang Hang-Suk;Park Cheong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.14 no.2
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    • pp.191-198
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    • 1998
  • Objectives: We performed an immunohistochemical study to examine the place of neovascularization in the tumorigenic process of follicular thyroid carcinoma and to determine whether tumor angiogenic activity in follicular carcinoma plays a role in tumor aggression. Materials & Methods: We studied 63 follicular thyroid carcinomas and compared with 22 follicular adenomas. The areas of capsular invasion, vascular invasion and cellular atypism of the tumor were confimed on H & E stains. The paraffin embedded tissues were stained by the use of monoclonal antibodies against Ag CD34. Microvesseles were counted in the area of highest vascular density at 200 times magnification. The microvessel densities(MVD) were analized in relation to histologic type and location of the tumors. Results: There were 59 minimal invasive types and 4 widely invasive types of carcinoma. In the histologic specimens of carcinomas, capsular invasion was identified in all the cases, vascular invasion in 46 and cellular atypism in 24. Mean values of the MVDs of the minimal invasive carcinomas, the widely invasive carcinomas and the adenomas were $263.8{\pm}69.2,\;256.l{\pm}49.3\;and\;241.5{\pm}159.4$, respectively and there was no significant difference between each group. In follicular carcinomas, there was a regional difference of the MVDs. The areas of tumor showing cellular atypism and adjacent to or penetrating the capsule, in which represents the tumorigenic process of carcinoma, had a higher rate of vascularization, than other areas of the tumor(p<0.05). However, these features were not noted in the follicular adenomas. Conclusion: Although there was no significant difference of the MVD between follicular carcinomas and adenomas, there was a regional difference of the MVD within the carcinomas and the values were significantly higher in the more malignant areas, as indicated by cellular atypism and capsular invasion. Therefore, tumor angiogenic activity measured by MVD may play a role in tumor aggression in follicular thyroid carcinoma.

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Nucleus Recognition of Uterine Cervical Pap-Smears using Fuzzy Reasoning Rule (퍼지 추론 규칙을 이용한 자궁 경부진 핵 인식)

  • Kim, Kwang-Baek;Song, Doo-Heon
    • Journal of the Korea Society of Computer and Information
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    • v.13 no.3
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    • pp.179-187
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    • 2008
  • In this paper, we apply a set of algorithms to classily normal and cancer nucleus from uterine cervical pap-smear images. First, we use lightening compensation algorithm to restore color images that have defamation through the process of obtaining $1{\times}400$ microscope magnification. Then, we remove the background from images with the histogram distributions of RGB regions. We extract nucleus areas from candidates by applying histogram brightness, Kapur method, and our own 8-direction contour tracing algorithm. Various binarization, cumulative entropy, masking algorithms are used in that process. Then, we are able to recognize normal and cancer nucleus from those areas by using three morphological features - directional information, the size of nucleus, and area ratio - with fuzzy membership functions and deciding rules we devised. The experimental result shows our method has low false recognition rate.

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Analysis of Material Properties According to Compounding Conditions of Polymer Composites to Reduce Thermal Deformation (열변형 저감을 위한 고분자 복합소재 배합 조건에 따른 재료특성 분석)

  • Byun, Sangwon;Kim, Youngshin;Jeon, Euy sik
    • Journal of the Semiconductor & Display Technology
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    • v.21 no.1
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    • pp.148-154
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    • 2022
  • As the 4th industrial age approaches, the demand for semiconductors is increasing enough to be used in all electronic devices. At the same time, semiconductor technology is also developing day by day, leading to ultraprecision and low power consumption. Semiconductors that keep getting smaller generate heat because the energy density increases, and the generated heat changes the shape of the semiconductor package, so it is important to manage. The temperature change is not only self-heating of the semiconductor package, but also heat generated by external damage. If the package is deformed, it is necessary to manage it because functional problems and performance degradation such as damage occur. The package burn in test in the post-process of semiconductor production is a process that tests the durability and function of the package in a high-temperature environment, and heat dissipation performance can be evaluated. In this paper, we intend to review a new material formulation that can improve the performance of the adapter, which is one of the parts of the test socket used in the burn-in test. It was confirmed what characteristics the basic base showed when polyamide, a high-molecular material, and alumina, which had high thermal conductivity, were mixed for each magnification. In this study, functional evaluation was also carried out by injecting an adapter, a part of the test socket, at the same time as the specimen was manufactured. Verification of stiffness such as tensile strength and flexural strength by mixing ratio, performance evaluation such as thermal conductivity, and manufacturing of a dummy device also confirmed warpage. As a result, it was confirmed that the thermal stability was excellent. Through this study, it is thought that it can be used as basic data for the development of materials for burn-in sockets in the future.

A Comparative Study on the Marginal Fit between Castable Ceramic(Dicor) Crowns and Metal-Ceramic Crowns (주조도재관과 도재전장주조관의 치경부 변연적합도에 관한 비교 연구)

  • Kim, Jeong-Ho;Yang, Jae-Ho;Lee, Sun-Hyung
    • The Journal of Korean Academy of Prosthodontics
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    • v.26 no.1
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    • pp.51-61
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    • 1988
  • The recently introduced castable glass ceramics incorporate properties characteristic of natural teeth and they are regarded as an ideal material to restore lost tooth structure. The purpose of this study was to compare the marginal fit of castable ceramic crown with that of the metal-ceramic crown in the process of heat treatment. Two master dies for castable ceramic crowns and metal-ceramic crowns were fabricated from being cast with the base metal. Each master die was duplicated with addition silicone and hard stone. Ten castable ceramic crowns were made on each hard stone die and their marginal openings were measured three times first, after casting; second, after ceramming; third, after shading. The other ten metal-ceramic crowns were made on each hard stone die and their marginal openings were measured three times : first, after casting; second, after degassing; third, after porcelain veneering. Each crown was seated on its master die with the constant force delivered by loading jig. And then, marginal openings were measured on four locations by optical projector at X50 magnification. The results were as follows: 1. The mean marginal openings of castable ceramic crowns were $31.1{\pm}12.7{\mu}m$ after casting; $44.6{\pm}12.8{\mu}m$ after ceramming; $51.2{\pm}16.8{\mu}m$ after shading. 2. The mean marginal openings of the metal-ceramic crowns were $26.2{\pm}13.8{\mu}m$ after casting; $29.8{\pm}10.3{\mu}m$ after degassing; $38.0{\pm}14.5{\mu}m$ after porcelain veneering. 3. There was significant increase in the marginal opening of castable ceramic crowns after ceramming, while metal-ceramic crowns sho(wed significant increase after porcelain veneering (p<0.05). 4. Marginal fit of metal-ceramic crown was better than that of castable ceramic crown (p<0.01).

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A Simple Method to Determination the Rotation Angle Between an Image and its Diffraction Pattern with LACBED Patterns (LACBED 패턴으로부터 전자현미경 상에 대한 회절도형의 회전각을 측정하는 간단한 방법)

  • Kim, Hwang-Su;Kim, Jong-Pil
    • Applied Microscopy
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    • v.33 no.3
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    • pp.187-193
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    • 2003
  • When electron microscope images and selected area diffraction patterns of crystalline materials are being compared, it is important to know for the rotation of the diffraction pattern with respect to the image caused by the magnetic lens in the Electron Microscope. A well-known method to determine this rotation is to use a test crystal of $MoO_3$. But this method of determination of the rotation angle contains an uncertainty of $180^{\circ}$. Thus one has to devise another way to eliminate this uncertainty. In this paper we present a new and simple method of determining this rotation without any complexity. The method involves a process of obtaining LACBED patterns of crystalline materials. For the J2010 electron microscope, the rotation is determined to be $180^{\circ}$ and this angle remains unchanged for changing of the magnification and the camera length.

A Study of Deformation Depicted on Moschino's Collection -Focusing on 2006~2010 Year Collection- (모스키노 컬렉션에 표현된 데포르마시옹에 관한 연구 -2006~2010년의 Collection을 중심으로-)

  • Lee, Jee-Yeon;Cho, Jean-Suk
    • The Research Journal of the Costume Culture
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    • v.19 no.3
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    • pp.488-500
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    • 2011
  • [ $D{\'{e}}formation$ ]is one of the most important cultural factor which puts people at ease and gives a sense of security. This study, in the process, analyzes the works of Moschino. Moschino's designs are rated to have approached the sublime when it comes to transforming the psychological anxiety of everyday living into a laughter. After selecting one hundred-two of Moschino's designs from the Internet Web site(www.cft.or.kr, www.samsungdesign.net), this study examines and analyzes the characteristics and types of deformation found in them. The result as follows. The examination of deformation found in Moschino designs can be classified into a transformation, distortion, exaggeration, and illusion. Transformation, a conscious change of the existing form or function, was shown as the change of an existing position, form, function and designation of a new function. Distortion, an interpretation away from the reality or a "wrong interpretation," was shown by placing opposing factors in left-right position as an extreme asymmetry. Exaggeration, always beyond the realm of reality, was shown thorough an enlargement or a magnification of a specific part and a repetition of a detail factors. Illusion, through a distortion of reality results in something that looks new, was expressed through the effects of wearing a two-pieces, an expression of details, effects of wearing accessories, and an expression of a dynamism. Therefore, Moschino has reflected the desire of homo modern to transform the existing situation through many techniques of deformation.

Investigation of Micromorphological Characteristics of Acupuncture Needle Tip Using SEM-EDX (SEM-EDX를 이용한 침 끝의 미세 부착물의 조성에 대한 관찰)

  • Jang, In-Soo;Son, Dong-Hyuk;Song, Ho-Seop;Lee, In-Hwan;Park, Jong-Bae
    • Journal of Acupuncture Research
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    • v.22 no.6
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    • pp.135-140
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    • 2005
  • Objectives : There have been several studies about the quality of acupuncture needle tip recently. We have investigated the condition of the tip of the acupuncture needles in the last studies. In the former studies, we discovered the metallic scuff, lumps and irregularities of the acupuncture needle tips under the microscope. But, no information was available on those foreign materials' identity. Methods : We have selected 200 needles of 1000 pieces from several companies by randomized methods. And we observed the tip of the 6 needles selected finally at ${\times}1000\;or\;{\times}3000$ magnification and analyzed the components of the metallic scuff, lumps and irregularities of the needle tips with a SEM-EDX analyser. Results : We found that the identity of the metallic scuff, lumps and irregularities of the needle tips were metallic materials and silicon. For example, A point was composed of Fe(69.78%), Cr(17.71%), Ni(8.11%), Zn(2.04%), Si(1.23%), Mn(1.12%), and B point was composed of Si(66.40%), Fe(26.76%), Cr(6.84%). Conclusion : The results of this study confirm that there is a real possibility of the remaining of metallic materials and silicon in body of patient, after acupuncture treatment. Therefore, it is necessary to intensify our efforts to make needles of good quality and to concentrate on manufacturing process of acupuncture needles completely to be free from danger in acupuncture treatment.

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Nonlinear 3D Image Correlator Using Fast Computational Integral Imaging Reconstruction Method (고속 컴퓨터 집적 영상 복원 방법을 이용한 비선형 3D 영상 상관기)

  • Shin, Donghak;Lee, Joon-Jae
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.10
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    • pp.2280-2286
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    • 2012
  • In this paper, we propose a novel nonlinear 3D image correlator using a fast computational integral imaging reconstruction (CIIR) method. In order to implement the fast CIIR method, the magnification process was eliminated. In the proposed correlator, elemental images of the reference and target objects are picked up by lenslet arrays. Using these elemental images, reference and target plane images are reconstructed on the output plane by means of the proposed fast CIIR method. Then, through nonlinear cross-correlations between the reconstructed reference and the target plane images, the pattern recognition can be performed from the correlation outputs. Nonlinear correlation operation can improve the recognition of 3D objects. To show the feasibility of the proposed method, some preliminary experiments are carried out and the results are presented by comparing the conventional method.

Image Magnification using Fuzzy Method for Ultrasound Image of Abdominal Muscles (복부 초음파 영상에서의 퍼지 기법을 이용한 영상 확대)

  • Kim, Kwang-Baek;Lee, Hae-Jung
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.4
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    • pp.23-28
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    • 2011
  • Ultrasound images for the abdominal muscles are complicated enough to have difficulty in interpreting their results. For better interpretation, magnifying the original image is necessary but its magnified image could be deteriorated and suffer from information loss. Thus, in this paper, we propose a magnifying method that reduces the gap between the original image and the magnified one in quality using a fuzzy method with weights for its brightness and interpolation. The proposed method extracts information of pixels in magnified image that have most similar characteristics of the original one by applying fuzzy membership function. In the process, the difference in the brightness between pixels of the magnified image and the original one using bilinear interpolation method and the weight value using the interpolation from multiplied values of four pixels are supplied to the fuzzy membership function. In this experiment, the proposed method reduces the cloudy phenomenon appears commonly compared to the bilinear interpolation method among those qualitative issues of image interpretation.

The Comparison of the Benign Tumors Originating from the Peripheral Nerves (말초 신경에 발생한 양성 종양의 비교)

  • Kim, Joon-Buhm;Cha, Jin-Han;Kim, Sang-Yoon
    • Archives of Reconstructive Microsurgery
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    • v.1 no.1
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    • pp.39-44
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    • 1992
  • Benign peripheral nerve tumors, although infrequent, must be considered as a possible cause of pain and disability in the extremities. There are three varieties of these tumors that are of clinical importance: neurilemmomas, neurofibromas, and post-traumatic neuroma. Neurilemmomas are the most common primary solitary tumor of the peripheral nerve trunks, and are almost always benign, Neurofibromas may occur as a solitary nerve tumor, but can present as multiple lesions as in von Recklinghausen's disease. Clinically, this tumor may presents as a solitary mass in the subcutaneous tissue which is centrally located with the nerve fibers travelling through the tumor mass. Traumatic neuroma is the proliferation of nerve elements with connective tissue during the process of regeneration from severed nerves undergoing Wallerian degeration, and is therefore not a true neoplasm. A neuroma-in-countinuity is the result of partial severance of a nerve, or of a crushing or traction injury in which all or part of the epineurium and perineurium is intact. We experienced each of the three varieties. With magnification, the neurilemmoma was removed by meticulous dissection from the parent nerve preserving the normal fascicles to which it was attached. The neurofibroma was excised and the nerve was reconstructed with interposed vein graft and the neuroma-in-continuity was excised and reconstructed with sural nerve graft. We report histologic characteristics of each tumors and the methods to repair the nerve defects after tumor excision with brief discussion.

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