• 한국초전도ㆍ저온공학회논문지
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• 제22권4호
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• pp.1-5
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• 2020

Heart consists of myocardium cells and the electrophysiological activity of the cells generate magnetic fields. By measuring this magnetic field, magnetocardiogram (MCG), functional diagnosis of the heart diseases is possible. Since the strength of the MCG signals is weak, typically in the range of 1-10 pT, we need sensitive magnetic sensors. Conventionally, superconducting quantum interference devices (SQUID)s were used for the detection of MCG signals due to its superior sensitivity to other magnetic sensors. However, drawback of the SQUID is the need for regular refill of a cryogenic liquid, typically liquid helium for cooling low-temperature SQUIDs. Efforts to eliminate the need for the refill in the SQUID system have been done by using cryocooler-based conduction cooling or use of non-cryogenic sensors, or room-temperature sensors. Each sensor has advantage and disadvantage, in terms of magnetic field sensitivity and complexity of the system, and we review the recent trend of MCG technology.

• Progress in Superconductivity
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• 제11권2호
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• pp.147-151
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• 2010

We have developed a high-$T_c$ SQUID magnetocardiogram (MCG) system for small laboratory animals. White noise of the measurement system was about 30 fT/$Hz^{1/2}$ when measured in a magnetically shielded room. We optimized the measurement position to obtain clear MCG wave from rat's small heart by using grid measurements. With the optimization, the MCG signal was successfully detected with the peak amplitude of about 30 pT. We could observe well defined P-, QRS-, and T-waves from the rat MCG. The results suggest that the developed system has a strong potential to monitor the progress of the heart disease model by using a laboratory rat.

• 대한의용생체공학회:의공학회지
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• 제27권2호
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• pp.59-63
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• 2006

Magnetocardiogram (MCG) topography is a useful diagnostic technique that employs multi-channel magnetocardiograms. Measurement of artifact-free MCG signals is essenctial to obtain MCG topography or map for a diagnosis of human heart. Principal component analysis (PCA) combined with an artificial neural network (ANN) is proposed to remove a pulse-type artifact in the MCG signals. The algorithm is composed of a PCA module which decomposes the obtained signal into its principal components, followed by an ANN module for the classification of the components automatically. In the experiments with volunteer subjects, 97% of the decisions that were made by the ANN were identical to those by the human experts. Using the proposed technique, the MCG topography was successfully obtained without the artifact.

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 2006년도 High Temperature Superconductivity Vol.XVI
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• pp.9-9
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• 2006

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 2004년도 High Temperature Superconductivity Vol.XIV
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• pp.54-54
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• 2004

• 한국초전도학회:학술대회논문집
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• 한국초전도학회 2005년도 High Temperature Superconductivity Vol.XV
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• pp.11-11
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• 2005

• Progress in Superconductivity
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• 제6권1호
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• pp.56-63
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• 2004

We consider design factors for a SQUID sensor array to construct a 52-channel magnetocardiogram (MCG) system that can be used to measure tangential components of the cardiac magnetic fields. Nowadays, full-size multichannel MCG systems, which cover the whole signal area of a heart, are developed to improve the clinical analysis with high accuracy and to provide patients with comfort in the course of measurement. To design the full-size MCG system, we have to make a compromise between cost and performance. The cost is involved with the number of sensors, the number of the electronics, the size of a cooling dewar, the consumption of refrigerants for maintenance, and etc. The performance is the capability of covering the whole heart volume at once and of localizing current sources with a small error. In this study, we design the cost-effective arrangement of sensors for MCG by considering an adequate sensor interval and the confidence region of a tolerable localization error, which covers the heart. In order to fit the detector array on the cylindrical dewar economically, we removed the detectors that were located at the corners of the array square. Through simulations using the confidence region method, we verified that our design of the detector array was good enough to obtain whole information from the heart at a time. A result of the simulation also suggested that tangential-component MCG measurement could localize deeper current dipoles than normal-component MCG measurement with the same confidence volume; therefore, we conclude that measurement of the tangential component is more suitable to an MCG system than measurement of the normal component.

• Progress in Superconductivity
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• 제5권1호
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• pp.38-44
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• 2003

The aim of this study is to confirm clinical usefulness of magnetocardiogram (MCG) by analyzing MCG data of health subjects and patients with Wolff-Parkinson-White (WPW) syndrome and dilated cardiomyopathy (DCM). Measurement of MCG signals was done with a home-made 40-channel SQUID system. MCG signals of 30 healthy subjects were measured as the reference of MCG signals. Among the DCM patients, 7 patients showed abnormal the direction of T wave vector. For a WPW syndrome patient, we measured the MCG signals before and after the surgery. and compared the difference. From the measured magnetic field distribution, current vector map was obtained to show the myocardium current activity. By comparing the MCG signals and current maps, we showed the differences in the analysis results between the healthy subjects and patients with heart diseases.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2003년도 somma/kms meeting
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• pp.303-303
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• 2003

• Progress in Superconductivity
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• 제4권2호
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• pp.121-126
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• 2003

The single layer direct-coupled YBCO SQUID magnetometers have been fabricated and characterized for the purpose of the measurement of weak magnetic signals in unshielded environment. Two types of magnetometers have been designed and fabricated using 10 mm$\times$ 10 mm substrates. We could operate the conventional 3-mm-wide solid pickup loop magnetometers more stably than the 12-parallel-line pickup loop magnetometers in laboratory environment. We developed a first-order electronic gradiometer system using the SQUID sensors with axial displacement of 80 mm without any mechanical alignment of magnetometers. The system with a software filter using calculation of discrete Fourier transform could record clearly weak pulse signal of 100 pT in a magnetically disturbed environment.